β2 microglobulin as a surrogate marker for HIV infection

Good correlation with CD4 counts

Ajay Wanchu, S. Arora, A. Bhatnagar, A. Sud, P. Bambery, S. Singh

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

To determine if beta-2 microglobulin (β2M) levels were elevated in our HIV infected patient population and if it could be used as a surrogate marker for disease progression. Thirty-eight HIV infected individuals and 26 age and sex-matched controls were studied. Measurement of CD4 cell count was carried out on a flow cytometer using anti-human CD4 monoclonal antibody and β2M was measured by an enzyme immunoassay. Mean levels of HIV infected individuals were 1.29±0.52 mg/L and were significantly higher than 0.74±0.07 mg/L, the value of controls (p value

Original languageEnglish (US)
Pages (from-to)298-301
Number of pages4
JournalIndian Journal of Pathology and Microbiology
Volume47
Issue number2
StatePublished - Apr 2004
Externally publishedYes

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CD4 Lymphocyte Count
HIV Infections
Biomarkers
HIV
beta 2-Microglobulin
Immunoenzyme Techniques
Disease Progression
Monoclonal Antibodies
Population

Keywords

  • β microglobulin
  • CD4 counts
  • Disease progression
  • HIV infection

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Microbiology (medical)

Cite this

Wanchu, A., Arora, S., Bhatnagar, A., Sud, A., Bambery, P., & Singh, S. (2004). β2 microglobulin as a surrogate marker for HIV infection: Good correlation with CD4 counts. Indian Journal of Pathology and Microbiology, 47(2), 298-301.

β2 microglobulin as a surrogate marker for HIV infection : Good correlation with CD4 counts. / Wanchu, Ajay; Arora, S.; Bhatnagar, A.; Sud, A.; Bambery, P.; Singh, S.

In: Indian Journal of Pathology and Microbiology, Vol. 47, No. 2, 04.2004, p. 298-301.

Research output: Contribution to journalArticle

Wanchu, A, Arora, S, Bhatnagar, A, Sud, A, Bambery, P & Singh, S 2004, 'β2 microglobulin as a surrogate marker for HIV infection: Good correlation with CD4 counts', Indian Journal of Pathology and Microbiology, vol. 47, no. 2, pp. 298-301.
Wanchu, Ajay ; Arora, S. ; Bhatnagar, A. ; Sud, A. ; Bambery, P. ; Singh, S. / β2 microglobulin as a surrogate marker for HIV infection : Good correlation with CD4 counts. In: Indian Journal of Pathology and Microbiology. 2004 ; Vol. 47, No. 2. pp. 298-301.
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