β-Adrenergic control of atrial natriuretic factor secretion from dispersed rat atrial myocytes

Daniel M. Gibbs

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

Adrenergic control of atrial natriuretic factor (ANF) secretion was studied using perifused, dispersed atrial myocytes. ANF secretion was stimulated by as little as 1 nM epinephrine (EPI) or the β-adrenergic agonist isoproterenol (ISO). The response to EPI was completely blocked by equimolar propranolol but not by phenoxybenzamine suggesting that, at least in this system, the adrenergic control of ANF secretion is mediated by β-adrenergic receptors.

Original languageEnglish (US)
Pages (from-to)73-78
Number of pages6
JournalRegulatory Peptides
Volume19
Issue number1-2
DOIs
StatePublished - Oct 1987

Keywords

  • Adrenergic receptor
  • Atrial natriuretic factor
  • Epinephrine

ASJC Scopus subject areas

  • Biochemistry
  • Physiology
  • Endocrinology
  • Clinical Biochemistry
  • Cellular and Molecular Neuroscience

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