PERIPHERAL AND CENTRAL HUMAN POSTURAL DISORDERS

Project: Research project

Description

Automatic postural adjustments responsible for human balance will be
studied in normal adults and in patients with disorders of posture
control. The goal of these studies is to define, quantitatively, the
normal repertoire of postural movement strategies in standing humans for
different speeds and directions, to address the question of relative
contribution of various types of sensory feedback versus central
programming in determination of postural strategy selection and then to
apply this approach to differentiating between the postural ataxia
associated with specific types of peripheral and central CNS-disordered
patients. The long term aim is to improve assessment and treatment of
patients with postural instability. Subjects will stand on a movable platform system. Postural adjustments to
a variety of different movement perturbations will be described by
analyzing the EMG activity of selected leg and lower trunk muscles and by
recording surface forces and motions of the ankle, knee, hip and neck
angles. Experiments are designed to test the hypothesis that the CNS
preprograms a discrete set of automatic postural strategies, each of which
is normally triggered within bounded stimulus conditions and that these
boundaries can change with neural pathology causing postural instability. Select groups of patients with peripheral vestibular deficits, peripheral
neuropathy and cerebellar deficits will be studied. The ability of
patients to select postural strategies appropriate to conditions as well as
the intactness of their postural synergy patterns will be determined.
StatusFinished
Effective start/end date1/1/8712/31/89

Funding

  • National Institutes of Health
  • National Institutes of Health

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Social Adjustment
Sensory Feedback
Aptitude
Ankle
Hip
Leg
Knee
Pathology
Muscles
Therapeutics
Direction compound

ASJC

  • Medicine(all)
  • Neuroscience(all)