Project Details
Description
This application proposes the use of a genetic approach to define the potential roles of luteinizing hormone releasing hormone (LHRH) and its receptors in the brain. Specifically, the investigator proposes to employ the bacteriophage P1-derived Cre-loxP recombination system in a gene targeting approach to selectively delete the LHRH receptor gene from brain neurons and/or astrocytes, without affecting expression of the gene in endocrine tissues, such as the pituitary gland and ovaries.
Status | Finished |
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Effective start/end date | 3/1/98 → 2/28/02 |
Funding
- National Institutes of Health
ASJC
- Medicine(all)
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