Growth of rheusus cytomegalovirus in macrophages

Project: Research project

Description

DESCRIPTION (provided by applicant): The purpose of this proposal is to develop rhesus cytomegalovirus (RhCMV) as model system for studying human cytomegalovirus pathogenesis. Specifically, we will be studying the growth determinants of RhCMV in monocyte-derived macrophages (also infected by human immunodeficiency virus or simian immunodeficiency virus), by using a transposon mutagenesis system and bacterial artificial chromosome (BAC) technology.
StatusFinished
Effective start/end date9/1/038/31/05

Funding

  • National Institutes of Health: $48,928.00
  • National Institutes of Health: $46,420.00

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Cytomegalovirus
Macrophages
Growth
Bacterial Artificial Chromosomes
Simian Immunodeficiency Virus
Mutagenesis
HIV
Technology

ASJC

  • Medicine(all)
  • Immunology and Microbiology(all)