Project Details
Description
While extensive progress has been made over the past decade in finding and
treating patients with hypertension, it has become increasingly obvious that
long term resolution of this problem will require a greater understanding of the
basic mechanisms involved so that preventive measures may be taken. Recent
studies have suggested that hypertension is the result of flaws in those systems
which normally regulate arterial pressure. The overall objective of this
proposal is to pursue studies designed to determine the mechanism(s) responsible
for the altered adrenal responses to angiotensin II in essential hypertension
and their pathophysiologic significance. Clinical studies will be conducted in
patients with essential hypertension and parallel studies in two control groups: normotensive subjects and patients with secondary forms of hypertension.
treating patients with hypertension, it has become increasingly obvious that
long term resolution of this problem will require a greater understanding of the
basic mechanisms involved so that preventive measures may be taken. Recent
studies have suggested that hypertension is the result of flaws in those systems
which normally regulate arterial pressure. The overall objective of this
proposal is to pursue studies designed to determine the mechanism(s) responsible
for the altered adrenal responses to angiotensin II in essential hypertension
and their pathophysiologic significance. Clinical studies will be conducted in
patients with essential hypertension and parallel studies in two control groups: normotensive subjects and patients with secondary forms of hypertension.
Status | Finished |
---|---|
Effective start/end date | 12/1/84 → 3/31/10 |
Funding
- National Institutes of Health
ASJC
- Medicine(all)
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