ESTABLISHMENT OF SPECIFIC PATHOGEN FREE RHESUS AND PIGTA

    Project: Research project

    Description

    DESCRIPTION (Provided by applicant): Opportunistic human viruses and their simian counterparts are similar in their genetic makeup and induce a similar spectrum of diseases in their immunosuppressed hosts. Experimental lentivirus infections in rhesus macaques are widely recognized as the most import animal model for AIDS-related research and there is an urgent need to expand breeding programs to meet future AIDS vaccine and pathogenesis research program needs. Development of an Indian rhesus macaque breeding colony free of opportunistic viral agents is proposed to enhance the usefulness of this unique resource for studies focused on AIDS-related opportunistic infections. Housing space is proposed to provide a protected environment for this unique Expanded Specific Pathogen Free (ESPF) macaque resource and to facilitate enhanced macaque breeding efforts.
    StatusFinished
    Effective start/end date9/30/028/31/12

    Funding

    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health: $741,430.00
    • National Institutes of Health: $872,503.00
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health: $635,419.00
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health: $1,515,234.00
    • National Institutes of Health: $1,414,947.00
    • National Institutes of Health
    • National Institutes of Health: $1,316,833.00
    • National Institutes of Health: $666,852.00
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health: $133,775.00
    • National Institutes of Health
    • National Institutes of Health: $1,337,758.00
    • National Institutes of Health
    • National Institutes of Health: $1,252,364.00
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health
    • National Institutes of Health: $698,731.00
    • National Institutes of Health
    • National Institutes of Health

    Fingerprint

    Macaca mulatta
    pathogens
    Macaca
    breeding
    vertebrate viruses
    Lentivirus
    vaccines
    animal models
    research programs
    imports
    infection
    pathogenesis
    immunology
    genome
    funding
    therapeutics
    Primates

    ASJC

    • Medicine(all)