CENTER FOR AIDS RESEARCH

The proposed UW CFAR is organized around 6 core units:
Administration (including information transfer/publications and
research training); clinical and molecular retrovirology;
immunology, clinical research; biostatistics and epidemiology
(including International AIDS Research and AIDS Registry); and non-
human primate research. Two additional core units, behavioral
sciences research and radiological imaging research, are envisioned
via separate funding in future years. Over 75 faculty staff
investigators of the proposed CFAR participate in active or pending
research grants directly related to AIDS, HIV, or SIV and many of
these also have other active grants in closely related fields such
as non-primate retrovirology, molecular/cellular immunology, and
other STDs. Ten distinct AIDS related themes have been identified,
many involving parallel research in humans and non-human primates.
The proposed CFAR would help coordinate this research to ensure
efficient use of primates in research most relevant to human
infection. Six active and two pending institutional post-doctoral
research or clinical training grants at the UW are AIDS related.
The process of planning this proposal has helped to coordinate the
new allocations of 7450 sq. ft. of lab space to basic research on
HIV and SIV. The CFAR would fund alteration, renovation, and
equipping of a portion of these labs on the UW campus and at Fred
Hutchinson Cancer Research Center. Planning for relocation of the
HMC AIDS Clinic and the NIAID ACTU is already funded and underway.
The CFAR would fund creation and co-location of a CFAR Clinical
Research unit, including clinical and epidemiologic research
trainees at the same site as the AIDS clinic and ACTU.