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Yoon-Jae Cho

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Calculated based on number of publications stored in Pure and citations from Scopus
19992023

Research activity per year

Search results

  • 2023

    Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma

    Chapman, O. S., Luebeck, J., Sridhar, S., Wong, I. T. L., Dixit, D., Wang, S., Prasad, G., Rajkumar, U., Pagadala, M. S., Larson, J. D., He, B. J., Hung, K. L., Lange, J. T., Dehkordi, S. R., Chandran, S., Adam, M., Morgan, L., Wani, S., Tiwari, A., Guccione, C., & 28 othersLin, Y., Dutta, A., Lo, Y. Y., Juarez, E., Robinson, J. T., Korshunov, A., Michaels, J. E. A., Cho, Y. J., Malicki, D. M., Coufal, N. G., Levy, M. L., Hobbs, C., Scheuermann, R. H., Crawford, J. R., Pomeroy, S. L., Rich, J. N., Zhang, X., Chang, H. Y., Dixon, J. R., Bagchi, A., Deshpande, A. J., Carter, H., Fraenkel, E., Mischel, P. S., Wechsler-Reya, R. J., Bafna, V., Mesirov, J. P. & Chavez, L., Dec 2023, In: Nature genetics. 55, 12, p. 2189-2199 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations
  • 2022

    AAV-vector based gene therapy for mitochondrial disease: progress and future perspectives

    Hanaford, A. R., Cho, Y. J. & Nakai, H., Dec 2022, In: Orphanet journal of rare diseases. 17, 1, 217.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    8 Scopus citations

  • Immune Checkpoint Inhibition as Single Therapy for Synchronous Cancers Exhibiting Hypermutation: An IRRDC Study

    Henderson, J. J., Das, A., Morgenstern, D. A., Sudhaman, S., Bianchi, V., Chung, J., Negm, L., Edwards, M., Kram, D. E., Osborn, M., Hawkins, C., Bouffet, E., Cho, Y. J. & Tabori, U., 2022, In: JCO Precision Oncology. 6, e2100286.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • MRI Radiogenomics of Pediatric Medulloblastoma: A Multicenter Study

    Zhang, M., Wong, S. W., Wright, J. N., Wagner, M. W., Toescu, S., Han, M., Tam, L. T., Zhou, Q., Ahmadian, S. S., Shpanskaya, K., Lummus, S., Lai, H., Eghbal, A., Radmanesh, A., Nemelka, J., Harward, S., Malinzak, M., Laughlin, S., Perreault, S., Braun, K. R. M., & 19 othersLober, R. M., Cho, Y. J., Ertl-Wagner, B., Ho, C. Y., Mankad, K., Vogel, H., Cheshier, S. H., Jacques, T. S., Aquilina, K., Fisher, P. G., Taylor, M., Poussaint, T., Vitanza, N. A., Grant, G. A., Pfister, S., Thompson, E., Jaju, A., Ramaswamy, V. & Yeom, K. W., Aug 2022, In: RADIOLOGY. 304, 2, p. 406-416 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    24 Scopus citations

  • Retraction Note: Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma (Nature Neuroscience, (2020), 10.1038/s41593-020-0628-4)

    Garancher, A., Suzuki, H., Haricharan, S., Chau, L. Q., Masihi, M. B., Rusert, J. M., Norris, P. S., Carrette, F., Romero, M. M., Morrissy, S. A., Skowron, P., Cavalli, F. M. G., Farooq, H., Ramaswamy, V., Jones, S. J. M., Moore, R. A., Mungall, A. J., Ma, Y., Thiessen, N., Li, Y., & 20 othersMorcavallo, A., Qi, L., Kogiso, M., Du, Y., Baxter, P., Henderson, J. J., Crawford, J. R., Levy, M. L., Olson, J. M., Cho, Y. J., Deshpande, A. J., Li, X. N., Chesler, L., Marra, M. A., Wajant, H., Becher, O. J., Bradley, L. M., Ware, C. F., Taylor, M. D. & Wechsler-Reya, R. J., Jan 2022, In: Nature Neuroscience. 25, 1, p. 127 1 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
  • 2021

    Barry Sheldon Russman

    Cho, Y. J., Jan 1 2021, Child Neurology: Its Origins, Founders, Growth and Evolution. Elsevier, p. 901-903 3 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Clinical Outcomes and Patient-Matched Molecular Composition of Relapsed Medulloblastoma

    Kumar, R., Smith, K. S., Deng, M., Terhune, C., Robinson, G. W., Orr, B. A., Liu, A. P. Y., Lin, T., Billups, C. A., Chintagumpala, M., Bowers, D. C., Hassall, T. E., Hansford, J. R., Khuong-Quang, D. A., Crawford, J. R., Bendel, A. E., Gururangan, S., Schroeder, K., Bouffet, E., Bartels, U., & 44 othersFisher, M. J., Cohn, R., Partap, S., Kellie, S. J., McCowage, G., Paulino, A. C., Rutkowski, S., Fleischhack, G., Dhall, G., Klesse, L. J., Leary, S., Nazarian, J., Kool, M., Wesseling, P., Ryzhova, M., Zheludkova, O., Golanov, A. V., McLendon, R. E., Packer, R. J., Dunham, C., Hukin, J., Fouladi, M., Faria, C. C., Pimentel, J., Walter, A. W., Jabado, N., Cho, Y. J., Perreault, S., Croul, S. E., Zapotocky, M., Hawkins, C., Tabori, U., Taylor, M. D., Pfister, S. M., Klimo, P., Boop, F. A., Ellison, D. W., Merchant, T. E., Onar-Thomas, A., Korshunov, A., Jones, D. T. W., Gajjar, A., Ramaswamy, V. & Northcott, P. A., Mar 1 2021, In: Journal of Clinical Oncology. 39, 7, p. 807-821 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • Mechanisms of targeted therapy resistance in a pediatric glioma driven by ETV6-NTRK3 fusion

    Keddy, C., Neff, T., Huan, J., Nickerson, J. P., Beach, C. Z., Akkari, Y., Ji, J., Moore, S., Nazemi, K. J., Corless, C. L., Beadling, C., Woltjer, R., Cho, Y. J., Wood, M. D. & Davare, M. A., Dec 2021, In: Cold Spring Harbor Molecular Case Studies. 7, 5, a006109.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations
  • 2020

    Erratum: Correction: Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide (Oncogene (2019) 38 42 (6867-6879))

    Nitta, R. T., Bolin, S., Luo, E., Solow-Cordero, D. E., Samghabadi, P., Purzner, T., Aujla, P. S., Nwagbo, G., Cho, Y. J. & Li, G., Feb 1 2020, In: Oncogene. 39, 9, p. 2029 1 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
    1 Scopus citations

  • Functional precision medicine identifies new therapeutic candidates for medulloblastoma

    Rusert, J. M., Juarez, E. F., Brabetz, S., Jensen, J., Garancher, A., Chau, L. Q., Tacheva-Grigorova, S. K., Wahab, S., Udaka, Y. T., Finlay, D., Seker-Cin, H., Reardon, B., Grobner, S., Serrano, J., Ecker, J., Qi, L., Kogiso, M., Du, Y., Baxter, P. A., Henderson, J. J., & 20 othersBerens, M. E., Vuori, K., Milde, T., Cho, Y. J., Li, X. N., Olson, J. M., Reyes, I., Snuderl, M., Wong, T. C., Dimmock, D. P., Nahas, S. A., Malicki, D., Crawford, J. R., Levy, M. L., van Allen, E. M., Pfister, S. M., Tamayo, P., Kool, M., Mesirov, J. P. & Wechsler-Reya, R. J., Dec 1 2020, In: Cancer Research. 80, 23, p. 5393-5407 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • Measure Twice: Promise of Liquid Biopsy in Pediatric High-Grade Gliomas

    Dietz, M. S., Beach, C. Z., Barajas, R., Parappilly, M. S., Sengupta, S. K., Baird, L. C., Ciporen, J. N., Han, S. J., Loret de Mola, R., Cho, Y. J., Nazemi, K. J., McClelland, S., Wong, M. H. & Jaboin, J. J., Mar 1 2020, In: Advances in Radiation Oncology. 5, 2, p. 152-162 11 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    4 Scopus citations

  • Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma

    Garancher, A., Suzuki, H., Haricharan, S., Chau, L. Q., Masihi, M. B., Rusert, J. M., Norris, P. S., Carrette, F., Romero, M. M., Morrissy, S. A., Skowron, P., Cavalli, F. M. G., Farooq, H., Ramaswamy, V., Jones, S. J. M., Moore, R. A., Mungall, A. J., Ma, Y., Thiessen, N., Li, Y., & 20 othersMorcavallo, A., Qi, L., Kogiso, M., Du, Y., Baxter, P., Henderson, J. J., Crawford, J. R., Levy, M. L., Olson, J. M., Cho, Y. J., Deshpande, A. J., Li, X. N., Chesler, L., Marra, M. A., Wajant, H., Becher, O. J., Bradley, L. M., Ware, C. F., Taylor, M. D. & Wechsler-Reya, R. J., Jul 1 2020, In: Nature Neuroscience. 23, 7, p. 842-853 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations
  • 2019

    BMI1 is a therapeutic target in recurrent medulloblastoma

    Bakhshinyan, D., Venugopal, C., Adile, A. A., Garg, N., Manoranjan, B., Hallett, R., Wang, X., Mahendram, S., Vora, P., Vijayakumar, T., Subapanditha, M., Singh, M., Kameda-Smith, M. M., Qazi, M., McFarlane, N., Mann, A., Ajani, O. A., Yarascavitch, B., Ramaswamy, V., Farooq, H., & 18 othersMorrissy, S., Cao, L., Sydorenko, N., Baiazitov, R., Du, W., Sheedy, J., Weetall, M., Moon, Y. C., Lee, C. S., Kwiecien, J. M., Delaney, K. H., Doble, B., Cho, Y. J., Mitra, S., Kaplan, D., Taylor, M. D., Davis, T. W. & Singh, S. K., Mar 7 2019, In: Oncogene. 38, 10, p. 1702-1716 15 p.

    Research output: Contribution to journal › Article › peer-review

    21 Scopus citations

  • Casein kinase 2 inhibition sensitizes medulloblastoma to temozolomide

    Nitta, R. T., Bolin, S., Luo, E., Solow-Codero, D. E., Samghabadi, P., Purzner, T., Aujla, P. S., Nwagbo, G., Cho, Y. J. & Li, G., Oct 17 2019, In: Oncogene. 38, 42, p. 6867-6879 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations

  • Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis

    Huang, M., Tailor, J., Zhen, Q., Gillmor, A. H., Miller, M. L., Weishaupt, H., Chen, J., Zheng, T., Nash, E. K., McHenry, L. K., An, Z., Ye, F., Takashima, Y., Clarke, J., Ayetey, H., Cavalli, F. M. G., Luu, B., Moriarity, B. S., Ilkhanizadeh, S., Chavez, L., & 18 othersYu, C., Kurian, K. M., Magnaldo, T., Sevenet, N., Koch, P., Pollard, S. M., Dirks, P., Snyder, M. P., Largaespada, D. A., Cho, Y. J., Phillips, J. J., Swartling, F. J., Morrissy, A. S., Kool, M., Pfister, S. M., Taylor, M. D., Smith, A. & Weiss, W. A., Sep 5 2019, In: Cell Stem Cell. 25, 3, p. 433-446.e7

    Research output: Contribution to journal › Article › peer-review

    Open Access
    49 Scopus citations

  • MR imaging-based radiomic signatures of distinct molecular subgroups of medulloblastoma

    Iv, M., Zhou, M., Shpanskaya, K., Perreault, S., Wang, Z., Tranvinh, E., Lanzman, B., Vajapeyam, S., Vitanza, N. A., Fisher, P. G., Cho, Y. J., Laughlin, S., Ramaswamy, V., Taylor, M. D., Cheshier, S. H., Grant, G. A., Young Poussaint, T., Gevaert, O. & Yeom, K. W., Jan 1 2019, In: American Journal of Neuroradiology. 40, 1, p. 154-161 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    81 Scopus citations

  • Tetanus in an unvaccinated child - Oregon, 2017

    Guzman-Cottrill, J. A., Lancioni, C., Eriksson, C., Cho, Y. J. & Liko, J., Mar 8 2019, In: Morbidity and Mortality Weekly Report. 68, 9, p. 231-232 2 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
    12 Scopus citations
  • 2018

    A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases

    Garzia, L., Kijima, N., Morrissy, A. S., De Antonellis, P., Guerreiro-Stucklin, A., Holgado, B. L., Wu, X., Wang, X., Parsons, M., Zayne, K., Manno, A., Kuzan-Fischer, C., Nor, C., Donovan, L. K., Liu, J., Qin, L., Garancher, A., Liu, K. W., Mansouri, S., Luu, B., & 34 othersThompson, Y. Y., Ramaswamy, V., Peacock, J., Farooq, H., Skowron, P., Shih, D. J. H., Li, A., Ensan, S., Robbins, C. S., Cybulsky, M., Mitra, S., Ma, Y., Moore, R., Mungall, A., Cho, Y. J., Weiss, W. A., Chan, J. A., Hawkins, C. E., Massimino, M., Jabado, N., Zapotocky, M., Sumerauer, D., Bouffet, E., Dirks, P., Tabori, U., Sorensen, P. H. B., Brastianos, P. K., Aldape, K., Jones, S. J. M., Marra, M. A., Woodgett, J. R., Wechsler-Reya, R. J., Fults, D. W. & Taylor, M. D., Feb 22 2018, In: Cell. 172, 5, p. 1050-1062.e14

    Research output: Contribution to journal › Article › peer-review

    Open Access
    61 Scopus citations

  • Combined BET bromodomain and CDK2 inhibition in MYC-driven medulloblastoma

    Bolin, S., Borgenvik, A., Persson, C. U., Sundström, A., Qi, J., Bradner, J. E., Weiss, W. A., Cho, Y. J., Weishaupt, H. & Swartling, F. J., May 1 2018, In: Oncogene. 37, 21, p. 2850-2862 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    64 Scopus citations

  • Developmental phosphoproteomics identifies the kinase CK2 as a driver of Hedgehog signaling and a therapeutic target in medulloblastoma

    Purzner, T., Purzner, J., Buckstaff, T., Cozza, G., Gholamin, S., Rusert, J. M., Hartl, T. A., Sanders, J., Conley, N., Ge, X., Langan, M., Ramaswamy, V., Ellis, L., Litzenburger, U., Bolin, S., Theruvath, J., Nitta, R., Qi, L., Li, X. N., Li, G., & 7 othersTaylor, M. D., Wechsler-Reya, R. J., Pinna, L. A., Cho, Y. J., Fuller, M. T., Elias, J. E. & Scott, M. P., Sep 11 2018, In: Science signaling. 11, 547, eaau5147.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    52 Scopus citations

  • Erratum: A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases (S0092867418301156 (2018) 172(5) (1050–1062.e14) (S0092867418301156) (10.1016/j.cell.2018.01.038))

    Garzia, L., Kijima, N., Morrissy, A. S., De Antonellis, P., Guerreiro-Stucklin, A., Holgado, B. L., Wu, X., Wang, X., Parsons, M., Zayne, K., Manno, A., Kuzan-Fischer, C., Nor, C., Donovan, L. K., Liu, J., Qin, L., Garancher, A., Liu, K. W., Mansouri, S., Luu, B., & 34 othersThompson, Y. Y., Ramaswamy, V., Peacock, J., Farooq, H., Skowron, P., Shih, D. J. H., Li, A., Ensan, S., Robbins, C. S., Cybulsky, M., Mitra, S., Ma, Y., Moore, R., Mungall, A., Cho, Y. J., Weiss, W. A., Chan, J. A., Hawkins, C. E., Massimino, M., Jabado, N., Zapotocky, M., Sumerauer, D., Bouffet, E., Dirks, P., Tabori, U., Sorensen, P. H. B., Brastianos, P. K., Aldape, K., Jones, S. J. M., Marra, M. A., Woodgett, J. R., Wechsler-Reya, R. J., Fults, D. W. & Taylor, M. D., May 31 2018, In: Cell. 173, 6, p. 1549 1 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
    26 Scopus citations

  • Erratum to: Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma (Nature Communications, (2018), 9, 1, (4121), 10.1038/s41467-018-06564-9)

    Kahn, S. A., Wang, X., Nitta, R. T., Gholamin, S., Theruvath, J., Hutter, G., Azad, T. D., Wadi, L., Bolin, S., Ramaswamy, V., Esparza, R., Liu, K. W., Edwards, M., Swartling, F. J., Sahoo, D., Li, G., Wechsler-Reya, R. J., Reimand, J., Cho, Y. J., Taylor, M. D., & 3 othersWeissman, I. L., Mitra, S. S. & Cheshier, S. H., Dec 1 2018, In: Nature communications. 9, 1, 4651.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
    2 Scopus citations

  • Notch1 regulates the initiation of metastasis and self-renewal of Group 3 medulloblastoma

    Kahn, S. A., Wang, X., Nitta, R. T., Gholamin, S., Theruvath, J., Hutter, G., Azad, T. D., Wadi, L., Bolin, S., Ramaswamy, V., Esparza, R., Liu, K. W., Edwards, M., Swartling, F. J., Sahoo, D., Li, G., Wechsler-Reya, R. J., Reimand, J., Cho, Y. J., Taylor, M. D., & 3 othersWeissman, I. L., Mitra, S. S. & Cheshier, S. H., Dec 1 2018, In: Nature communications. 9, 1, 4121.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations
  • 2017

    A first-in-class twist1 inhibitor with activity in oncogene-driven lung cancer

    Yochum, Z. A., Cades, J., Mazzacurati, L., Neumann, N. M., Khetarpal, S. K., Chatterjee, S., Wang, H., Attar, M. A., Huang, E. H. B., Chatley, S. N., Nugent, K., Somasundaram, A., Engh, J. A., Ewald, A. J., Cho, Y. J., Rudin, C. M., Tran, P. T. & Burns, T. F., Dec 2017, In: Molecular Cancer Research. 15, 12, p. 1764-1776 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    59 Scopus citations

  • Disrupting the CD47-SIRPα anti-phagocytic axis by a humanized anti-CD47 antibody is an efficacious treatment for malignant pediatric brain tumors

    Gholamin, S., Mitra, S. S., Feroze, A. H., Liu, J., Kahn, S. A., Zhang, M., Esparza, R., Richard, C., Ramaswamy, V., Remke, M., Volkmer, A. K., Willingham, S., Ponnuswami, A., McCarty, A., Lovelace, P., Storm, T. A., Schubert, S., Hutter, G., Narayanan, C., Chu, P., & 14 othersRaabe, E. H., Harsh, G., Taylor, M. D., Monje, M., Cho, Y. J., Majeti, R., Volkmer, J. P., Fisher, P. G., Grant, G., Steinberg, G. K., Vogel, H., Edwards, M., Weissman, I. L. & Cheshier, S. H., Mar 15 2017, In: Science translational medicine. 9, 381, eaaf2968.

    Research output: Contribution to journal › Article › peer-review

    293 Scopus citations

  • Functional validation of the oncogenic cooperativity and targeting potential of tuberous sclerosis mutation in medulloblastoma using a MYC-amplified model cell line

    Henderson, J. J., Wagner, J. P., Hofmann, N. E., Eide, C. A., Cho, Y. J., Druker, B. J. & Davare, M. A., Oct 2017, In: Pediatric Blood and Cancer. 64, 10, e26553.

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations

  • Other Embryonal and Pineal Malignancies of the Central Nervous System

    Gertsch, E., Cho, Y. J. & Pomeroy, S. L., May 11 2017, Swaiman's Pediatric Neurology: Principles and Practice: Sixth Edition. Elsevier Inc., p. 969-972 4 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Pediatric high-grade glioma: Biologically and clinically in need of new thinking

    Jones, C., Karajannis, M. A., Jones, D. T. W., Kieran, M. W., Monje, M., Baker, S. J., Becher, O. J., Cho, Y. J., Gupta, N., Hawkins, C., Hargrave, D., Haas-Kogan, D. A., Jabado, N., Li, X. N., Mueller, S., Nicolaides, T., Packer, R. J., Persson, A. I., Phillips, J. J., Simonds, E. F., & 4 othersStafford, J. M., Tang, Y., Pfister, S. M. & Weiss, W. A., 2017, In: Neuro-Oncology. 19, 2, p. 153-161 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    256 Scopus citations

  • Pediatric oncology enters an era of precision medicine

    Seibel, N. L., Janeway, K., Allen, C. E., Chi, S. N., Cho, Y. J., Glade Bender, J. L., Kim, A. R., Laetsch, T. W., Irwin, M. S., Takebe, N., Tricoli, J. V. & Parsons, D. W., May 2017, In: Current problems in cancer. 41, 3, p. 194-200 7 p.

    Research output: Contribution to journal › Article › peer-review

    37 Scopus citations

  • Target and Agent Prioritization for the Children's Oncology Group - National Cancer Institute Pediatric MATCH Trial

    Pediatric MATCH Target and Agent Prioritization Committee, May 1 2017, In: Journal of the National Cancer Institute. 109, 5

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    83 Scopus citations

  • The whole-genome landscape of medulloblastoma subtypes

    Northcott, P. A., Buchhalter, I., Morrissy, A. S., Hovestadt, V., Weischenfeldt, J., Ehrenberger, T., Gröbner, S., Segura-Wang, M., Zichner, T., Rudneva, V. A., Warnatz, H. J., Sidiropoulos, N., Phillips, A. H., Schumacher, S., Kleinheinz, K., Waszak, S. M., Erkek, S., Jones, D. T. W., Worst, B. C., Kool, M., & 67 othersZapatka, M., Jäger, N., Chavez, L., Hutter, B., Bieg, M., Paramasivam, N., Heinold, M., Gu, Z., Ishaque, N., Jäger-Schmidt, C., Imbusch, C. D., Jugold, A., Hübschmann, D., Risch, T., Amstislavskiy, V., Gonzalez, F. G. R., Weber, U. D., Wolf, S., Robinson, G. W., Zhou, X., Wu, G., Finkelstein, D., Liu, Y., Cavalli, F. M. G., Luu, B., Ramaswamy, V., Wu, X., Koster, J., Ryzhova, M., Cho, Y. J., Pomeroy, S. L., Herold-Mende, C., Schuhmann, M., Ebinger, M., Liau, L. M., Mora, J., McLendon, R. E., Jabado, N., Kumabe, T., Chuah, E., Ma, Y., Moore, R. A., Mungall, A. J., Mungall, K. L., Thiessen, N., Tse, K., Wong, T., Jones, S. J. M., Witt, O., Milde, T., Von Deimling, A., Capper, D., Korshunov, A., Yaspo, M. L., Kriwacki, R., Gajjar, A., Zhang, J., Beroukhim, R., Fraenkel, E., Korbel, J. O., Brors, B., Schlesner, M., Eils, R., Marra, M. A., Pfister, S. M., Taylor, M. D. & Lichter, P., Jul 19 2017, In: Nature. 547, 7663, p. 311-317 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    691 Scopus citations
  • 2016

    Advances in the biology and treatment of pediatric central nervous system tumors

    Vitanza, N. A. & Cho, Y. J., Feb 1 2016, In: Current Opinion in Pediatrics. 28, 1, p. 34-39 6 p.

    Research output: Contribution to journal › Review article › peer-review

    10 Scopus citations

  • Divergent clonal selection dominates medulloblastoma at recurrence

    Morrissy, A. S., Garzia, L., Shih, D. J. H., Zuyderduyn, S., Huang, X., Skowron, P., Remke, M., Cavalli, F. M. G., Ramaswamy, V., Lindsay, P. E., Jelveh, S., Donovan, L. K., Wang, X., Luu, B., Zayne, K., Li, Y., Mayoh, C., Thiessen, N., Mercier, E., Mungall, K. L., & 118 othersMa, Y., Tse, K., Zeng, T., Shumansky, K., Roth, A. J. L., Shah, S., Farooq, H., Kijima, N., Holgado, B. L., Lee, J. J. Y., Matan-Lithwick, S., Liu, J., Mack, S. C., Manno, A., Michealraj, K. A., Nor, C., Peacock, J., Qin, L., Reimand, J., Rolider, A., Thompson, Y. Y., Wu, X., Pugh, T., Ally, A., Bilenky, M., Butterfield, Y. S. N., Carlsen, R., Cheng, Y., Chuah, E., Corbett, R. D., Dhalla, N., He, A., Lee, D., Li, H. I., Long, W., Mayo, M., Plettner, P., Qian, J. Q., Schein, J. E., Tam, A., Wong, T., Birol, I., Zhao, Y., Faria, C. C., Pimentel, J., Nunes, S., Shalaby, T., Grotzer, M., Pollack, I. F., Hamilton, R. L., Li, X. N., Bendel, A. E., Fults, D. W., Walter, A. W., Kumabe, T., Tominaga, T., Collins, V. P., Cho, Y. J., Hoffman, C., Lyden, D., Wisoff, J. H., Garvin, J. H., Stearns, D. S., Massimi, L., Schüller, U., Sterba, J., Zitterbart, K., Puget, S., Ayrault, O., Dunn, S. E., Tirapelli, D. P. C., Carlotti, C. G., Wheeler, H., Hallahan, A. R., Ingram, W., MacDonald, T. J., Olson, J. J., Van Meir, E. G., Lee, J. Y., Wang, K. C., Kim, S. K., Cho, B. K., Pietsch, T., Fleischhack, G., Tippelt, S., Ra, Y. S., Bailey, S., Lindsey, J. C., Clifford, S. C., Eberhart, C. G., Cooper, M. K., Packer, R. J., Massimino, M., Garre, M. L., Bartels, U., Tabori, U., Hawkins, C. E., Dirks, P., Bouffet, E., Rutka, J. T., Wechsler-Reya, R. J., Weiss, W. A., Collier, L. S., Dupuy, A. J., Korshunov, A., Jones, D. T. W., Kool, M., Northcott, P. A., Pfister, S. M., Largaespada, D. A., Mungall, A. J., Moore, R. A., Jabado, N., Bader, G. D., Jones, S. J. M., Malkin, D., Marra, M. A. & Taylor, M. D., Jan 21 2016, In: Nature. 529, 7586, p. 351-357 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    242 Scopus citations

  • FBW7 suppression leads to SOX9 stabilization and increased malignancy in medulloblastoma

    Suryo Rahmanto, A., Savov, V., Brunner, A., Bolin, S., Weishaupt, H., Malyukova, A., Rosén, G., Čančer, M., Hutter, S., Sundström, A., Kawauchi, D., Jones, D. T. W., Spruck, C., Taylor, M. D., Cho, Y. J., Pfister, S. M., Kool, M., Korshunov, A., Swartling, F. J. & Sangfelt, O., Oct 17 2016, In: EMBO Journal. 35, 20, p. 2192-2212 21 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    54 Scopus citations

  • HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma

    Pei, Y., Liu, K. W., Wang, J., Garancher, A., Tao, R., Esparza, L. A., Maier, D. L., Udaka, Y. T., Murad, N., Morrissy, S., Seker-Cin, H., Brabetz, S., Qi, L., Kogiso, M., Schubert, S., Olson, J. M., Cho, Y. J., Li, X. N., Crawford, J. R., Levy, M. L., & 4 othersKool, M., Pfister, S. M., Taylor, M. D. & Wechsler-Reya, R. J., Mar 14 2016, In: Cancer Cell. 29, 3, p. 311-323 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    192 Scopus citations

  • IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma

    Svalina, M. N., Kikuchi, K., Abraham, J., Lal, S., Davare, M. A., Settelmeyer, T. P., Young, M. C., Peckham, J. L., Cho, Y. J., Michalek, J. E., Hernandez, B. S., Berlow, N. E., Jackson, M., Guillaume, D. J., Selden, N. R., Bigner, D. D., Nazemi, K. J., Green, S. C., Corless, C. L., Gultekin, S., & 4 othersMansoor, A., Rubin, B. P., Woltjer, R. & Keller, C., Jun 3 2016, In: Scientific Reports. 6, 27012.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    17 Scopus citations

  • Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

    Oh, S., Flynn, R. A., Floor, S. N., Purzner, J., Martin, L., Do, B. T., Schubert, S., Vaka, D., Morrissy, S., Li, Y., Kool, M., Hovestadt, V., Jones, D. T. W., Northcott, P. A., Risch, T., Warnatz, H. J., Yaspo, M. L., Adams, C. M., Leib, R. D., Breese, M., & 8 othersMarra, M. A., Malkin, D., Lichter, P., Doudna, J. A., Pfister, S. M., Taylor, M. D., Chang, H. Y. & Cho, Y. J., May 10 2016, In: Oncotarget. 7, 19, p. 28169-28182 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    53 Scopus citations

  • Medulloblastoma Genotype Dictates Blood Brain Barrier Phenotype

    Phoenix, T. N., Patmore, D. M., Boop, S., Boulos, N., Jacus, M. O., Patel, Y. T., Roussel, M. F., Finkelstein, D., Goumnerova, L., Perreault, S., Wadhwa, E., Cho, Y. J., Stewart, C. F. & Gilbertson, R. J., Apr 11 2016, In: Cancer Cell. 29, 4, p. 508-522 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    214 Scopus citations

  • PI-3K inhibitors preferentially target CD15+ cancer stem cell population in SHH driven medulloblastoma

    Singh, A. R., Joshi, S., Zulcic, M., Alcaraz, M., Garlich, J. R., Morales, G. A., Cho, Y. J., Bao, L., Levy, M. L., Newbury, R., Malicki, D., Messer, K., Crawford, J. & Durden, D. L., Mar 2016, In: PloS one. 11, 3, e0150836.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    22 Scopus citations

  • Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis

    Thompson, E. M., Hielscher, T., Bouffet, E., Remke, M., Luu, B., Gururangan, S., McLendon, R. E., Bigner, D. D., Lipp, E. S., Perreault, S., Cho, Y. J., Grant, G., Kim, S. K., Lee, J. Y., Rao, A. A. N., Giannini, C., Li, K. K. W., Ng, H. K., Yao, Y., Kumabe, T., & 87 othersTominaga, T., Grajkowska, W. A., Perek-Polnik, M., Low, D. C. Y., Seow, W. T., Chang, K. T. E., Mora, J., Pollack, I. F., Hamilton, R. L., Leary, S., Moore, A. S., Ingram, W. J., Hallahan, A. R., Jouvet, A., Fèvre-Montange, M., Vasiljevic, A., Faure-Conter, C., Shofuda, T., Kagawa, N., Hashimoto, N., Jabado, N., Weil, A. G., Gayden, T., Wataya, T., Shalaby, T., Grotzer, M., Zitterbart, K., Sterba, J., Kren, L., Hortobágyi, T., Klekner, A., László, B., Pócza, T., Hauser, P., Schüller, U., Jung, S., Jang, W. Y., French, P. J., Kros, J. M., van Veelen, M. L. C., Massimi, L., Leonard, J. R., Rubin, J. B., Vibhakar, R., Chambless, L. B., Cooper, M. K., Thompson, R. C., Faria, C. C., Carvalho, A., Nunes, S., Pimentel, J., Fan, X., Muraszko, K. M., López-Aguilar, E., Lyden, D., Garzia, L., Shih, D. J. H., Kijima, N., Schneider, C., Adamski, J., Northcott, P. A., Kool, M., Jones, D. T. W., Chan, J. A., Nikolic, A., Garre, M. L., Van Meir, E. G., Osuka, S., Olson, J. J., Jahangiri, A., Castro, B. A., Gupta, N., Weiss, W. A., Moxon-Emre, I., Mabbott, D. J., Lassaletta, A., Hawkins, C. E., Tabori, U., Drake, J., Kulkarni, A., Dirks, P., Rutka, J. T., Korshunov, A., Pfister, S. M., Packer, R. J., Ramaswamy, V. & Taylor, M. D., Apr 1 2016, In: The Lancet Oncology. 17, 4, p. 484-495 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    249 Scopus citations
  • 2015

    A five-gene hedgehog signature developed as a patient preselection tool for hedgehog inhibitor therapy in medulloblastoma

    Shou, Y., Robinson, D. M., Amakye, D. D., Rose, K. L., Cho, Y. J., Ligon, K. L., Sharp, T., Haider, A. S., Bandaru, R., Ando, Y., Geoerger, B., Doz, F., Ashley, D. M., Hargrave, D. R., Casanova, M., Tawbi, H. A., Rodon, J., Thomas, A. L., Mita, A. C., MacDonald, T. J., & 1 othersKieran, M. W., Feb 1 2015, In: Clinical Cancer Research. 21, 3, p. 585-593 9 p.

    Research output: Contribution to journal › Article › peer-review

    45 Scopus citations

  • EphrinB1 expression is dysregulated and promotes oncogenic signaling in medulloblastoma

    McKinney, N., Yuan, L., Zhang, H., Liu, J., Cho, Y. J., Rushing, E., Schniederjan, M. & MacDonald, T. J., Jan 2015, In: Journal of Neuro-Oncology. 121, 1, p. 109-118 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Medulloblastoma subgroups remain stable across primary and metastatic compartments

    Wang, X., Dubuc, A. M., Ramaswamy, V., Mack, S., Gendoo, D. M. A., Remke, M., Wu, X., Garzia, L., Luu, B., Cavalli, F., Peacock, J., López, B., Skowron, P., Zagzag, D., Lyden, D., Hoffman, C., Cho, Y. J., Eberhart, C., MacDonald, T., Li, X. N., & 9 othersVan Meter, T., Northcott, P. A., Haibe-Kains, B., Hawkins, C., Rutka, J. T., Bouffet, E., Pfister, S. M., Korshunov, A. & Taylor, M. D., Feb 18 2015, In: Acta Neuropathologica. 129, 3, p. 449-457 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    75 Scopus citations

  • Mitochondrial p32 is upregulated in Myc expressing brain cancers and mediates glutamine addiction

    Fogal, V., Babic, I., Chao, Y., Pastorino, S., Mukthavaram, R., Jiang, P., Cho, Y. J., Pingle, S. C., Crawford, J. R., Piccioni, D. E. & Kesari, S., 2015, In: Oncotarget. 6, 2, p. 1157-1170 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    37 Scopus citations

  • Proteomic profiling of high risk medulloblastoma reveals functional biology

    Staal, J. A., Lau, L. S., Zhang, H., Ingram, W. J., Hallahan, A. R., Northcott, P. A., Pfister, S. M., Wechsler-Reya, R. J., Rusert, J. M., Taylor, M. D., Cho, Y. J., Packer, R. J., Brown, K. J. & Rood, B. R., 2015, In: Oncotarget. 6, 16, p. 14584-14595 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    18 Scopus citations
  • 2014

    Activation of β-catenin/TCF targets following loss of the tumor suppressor SNF5

    Mora-Blanco, E. L., Mishina, Y., Tillman, E. J., Cho, Y. J., Thom, C. S., Pomeroy, S. L., Shao, W. & Roberts, C. W. M., Feb 13 2014, In: Oncogene. 33, 7, p. 933-938 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    65 Scopus citations

  • Arhgap36-dependent activation of Gli transcription factors

    Rack, P. G., Ni, J., Payumo, A. Y., Nguyen, V., Crapster, J. A., Hovestadt, V., Kool, M., Jones, D. T. W., Mich, J. K., Firestone, A. J., Pfister, S. M., Cho, Y. J. & Chen, J. K., 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 30, p. 11061-11066 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • BET bromodomain inhibition of MYC-amplified medulloblastoma

    Bandopadhayay, P., Bergthold, G., Nguyen, B., Schubert, S., Gholamin, S., Tang, Y., Bolin, S., Schumacher, S. E., Zeid, R., Masoud, S., Yu, F., Vue, N., Gibson, W. J., Paolella, B. R., Mitra, S. S., Cheshier, S. H., Qi, J., Liu, K. W., Wechsler-Reya, R., Weiss, W. A., & 5 othersSwartling, F. J., Kieran, M. W., Bradner, J. E., Beroukhim, R. & Cho, Y. J., 2014, In: Clinical Cancer Research. 20, 4, p. 912-925 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    263 Scopus citations

  • Could α5-GABA-A receptor activation be used as a target for managing medulloblastomas?

    Sengupta, S., Weeraratne, S. D., Cho, Y. J. & Pomeroy, S. L., Jul 1 2014, In: CNS oncology. 3, 4, p. 245-247 3 p.

    Research output: Contribution to journal › Editorial › peer-review

    Open Access
    3 Scopus citations

  • Cytogenetic prognostication within medulloblastoma subgroups

    Shih, D. J. H., Northcott, P. A., Remke, M., Korshunov, A., Ramaswamy, V., Kool, M., Luu, B., Yao, Y., Wang, X., Dubuc, A. M., Garzia, L., Peacock, J., Mack, S. C., Wu, X., Rolider, A., Morrissy, A. S., Cavalli, F. M. G., Jones, D. T. W., Zitterbart, K., Faria, C. C., & 73 othersSchüller, U., Kren, L., Kumabe, T., Tominaga, T., Ra, Y. S., Garami, M., Hauser, P., Chan, J. A., Robinson, S., Bognár, L., Klekner, A., Saad, A. G., Liau, L. M., Albrecht, S., Fontebasso, A., Cinalli, G., De Antonellis, P., Zollo, M., Cooper, M. K., Thompson, R. C., Bailey, S., Lindsey, J. C., Di Rocco, C., Massimi, L., Michiels, E. M. C., Scherer, S. W., Phillips, J. J., Gupta, N., Fan, X., Muraszko, K. M., Vibhakar, R., Eberhart, C. G., Fouladi, M., Lach, B., Jung, S., Wechsler-Reya, R. J., Fèvre-Montange, M., Jouvet, A., Jabado, N., Pollack, I. F., Weiss, W. A., Lee, J. Y., Cho, B. K., Kim, S. K., Wang, K. C., Leonard, J. R., Rubin, J. B., De Torres, C., Lavarino, C., Mora, J., Cho, Y. J., Tabori, U., Olson, J. M., Gajjar, A., Packer, R. J., Rutkowski, S., Pomeroy, S. L., French, P. J., Kloosterhof, N. K., Kros, J. M., Van Meir, E. G., Clifford, S. C., Bourdeaut, F., Delattre, O., Doz, F. F., Hawkins, C. E., Malkin, D., Grajkowska, W. A., Perek-Polnik, M., Bouffet, E., Rutka, J. T., Pfister, S. M. & Taylor, M. D., Mar 20 2014, In: Journal of Clinical Oncology. 32, 9, p. 886-896 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    236 Scopus citations