Yiu Huen Tsang

Research Assistant Professor

  • 612 Citations
  • 12 h-Index
20072020

Research output per year

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Research Output

  • 612 Citations
  • 12 h-Index
  • 17 Article
  • 1 Editorial
Article

An inducible system for expression and validation of the specificity of short hairpin RNA in mammalian cells

Ma, H. T., On, K. F., Tsang, Y. H. & Poon, R. Y. C., Feb 1 2007, In : Nucleic acids research. 35, 4, e22.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations

Zhang, Y., Kwok-Shing Ng, P., Kucherlapati, M., Chen, F., Liu, Y., Tsang, Y. H., de Velasco, G., Jeong, K. J., Akbani, R., Hadjipanayis, A., Pantazi, A., Bristow, C. A., Lee, E., Mahadeshwar, H. S., Tang, J., Zhang, J., Yang, L., Seth, S., Lee, S., Ren, X. & 22 others, Song, X., Sun, H., Seidman, J., Luquette, L. J., Xi, R., Chin, L., Protopopov, A., Westbrook, T. F., Shelley, C. S., Choueiri, T. K., Ittmann, M., Van Waes, C., Weinstein, J. N., Liang, H., Henske, E. P., Godwin, A. K., Park, P. J., Kucherlapati, R., Scott, K. L., Mills, G. B., Kwiatkowski, D. J. & Creighton, C. J., Jun 12 2017, In : Cancer Cell. 31, 6, p. 820-832.e3

Research output: Contribution to journalArticle

104 Scopus citations

A-to-I-edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis

Xu, X., Wang, Y., Mojumdar, K., Zhou, Z., Jeong, K. J., Mangala, L. S., Yu, S., Tsang, Y. H., Rodriguez-Aguayo, C., Lu, Y., Lopez-Berestein, G., Sood, A. K., Mills, G. B. & Liang, H., Dec 2 2019, In : Journal of Clinical Investigation. 129, 12, p. 5343-5356 14 p.

Research output: Contribution to journalArticle

Open Access

A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer

Peng, X., Xu, X., Wang, Y., Hawke, D. H., Yu, S., Han, L., Zhou, Z., Mojumdar, K., Jeong, K. J., Labrie, M., Tsang, Y. H., Zhang, M., Lu, Y., Hwu, P., Scott, K. L., Liang, H. & Mills, G., May 14 2018, In : Cancer Cell. 33, 5, p. 817-828.e7

Research output: Contribution to journalArticle

35 Scopus citations

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

The Cancer Genome Atlas Research Network, Oct 30 2018, In : Cell Reports. 25, 5, p. 1304-1317.e5

Research output: Contribution to journalArticle

26 Scopus citations
Open Access
41 Scopus citations

Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression

Tsang, Y. H., Wang, Y., Kong, K., Grzeskowiak, C., Zagorodna, O., Dogruluk, T., Lu, H., Villafane, N., Bhavana, V. H., Moreno, D., Elsea, S. H., Liang, H., Mills, G. B. & Scott, K. L., Apr 2020, In : eLife. 9, e48963.

Research output: Contribution to journalArticle

Open Access

Engineering and functional characterization of fusion genes identifies novel oncogenic drivers of cancer

Lu, H., Villafane, N., Dogruluk, T., Grzeskowiak, C. L., Kong, K., Tsang, Y. H., Zagorodna, O., Pantazi, A., Yang, L., Neill, N. J., Kim, Y. W., Creighton, C. J., Verhaak, R. G., Mills, G. B., Park, P. J., Kucherlapati, R. & Scott, K. L., Jul 1 2017, In : Cancer Research. 77, 13, p. 3502-3512 11 p.

Research output: Contribution to journalArticle

9 Scopus citations

Functional annotation of rare gene aberration drivers of pancreatic cancer

Tsang, Y. H., Dogruluk, T., Tedeschi, P. M., Wardwell-Ozgo, J., Lu, H., Espitia, M., Nair, N., Minelli, R., Chong, Z., Chen, F., Chang, Q. E., Dennison, J. B., Dogruluk, A., Li, M., Ying, H., Bertino, J. R., Gingras, M. C., Ittmann, M., Kerrigan, J., Chen, K. & 4 others, Creighton, C. J., Eterovic, K., Mills, G. & Scott, K. L., Jan 25 2016, In : Nature Communications. 7, 10500.

Research output: Contribution to journalArticle

29 Scopus citations

Identification of variant-specific functions of PIK3CA by rapid phenotyping of rare mutations

Dogruluk, T., Tsang, Y. H., Espitia, M., Chen, F., Chen, T., Chong, Z., Appadurai, V., Dogruluk, A., Eterovic, A. K., Bonnen, P. E., Creighton, C. J., Chen, K., Mills, G. & Scott, K. L., Dec 15 2015, In : Cancer Research. 75, 24, p. 5341-5354 14 p.

Research output: Contribution to journalArticle

51 Scopus citations

In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer

Grzeskowiak, C. L., Kundu, S. T., Mo, X., Ivanov, A. A., Zagorodna, O., Lu, H., Chapple, R. H., Tsang, Y. H., Moreno, D., Mosqueda, M., Eterovic, K., Fradette, J. J., Ahmad, S., Chen, F., Chong, Z., Chen, K., Creighton, C. J., Fu, H., Mills, G., Gibbons, D. L. & 1 others, Scott, K. L., Dec 1 2018, In : Nature Communications. 9, 1, 2732.

Research output: Contribution to journalArticle

5 Scopus citations

Novel Functions of the Phosphatase SHP2 in the DNA Replication and Damage Checkpoints

Tsang, Y. H., Han, X., Man, W. Y., Lee, N. & Poon, R. Y. C., Nov 26 2012, In : PloS one. 7, 11, e49943.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

RNA editing derived epitopes function as cancer antigens to elicit immune responses

Zhang, M., Fritsche, J., Roszik, J., Williams, L. J., Peng, X., Chiu, Y., Tsou, C. C., Hoffgaard, F., Goldfinger, V., Schoor, O., Talukder, A., Forget, M. A., Haymaker, C., Bernatchez, C., Han, L., Tsang, Y. H., Kong, K., Xu, X., Scott, K. L., Singh-Jasuja, H. & 5 others, Lizee, G., Liang, H., Weinschenk, T., Mills, G. & Hwu, P., Dec 1 2018, In : Nature Communications. 9, 1, 3919.

Research output: Contribution to journalArticle

17 Scopus citations

Salt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death

Chen, H., Huang, S., Han, X., Zhang, J., Shan, C., Tsang, Y. H., Ma, H. T. & Poon, R. Y. C., Apr 2014, In : Cell Death and Disease. 5, 4, e1177.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Systematic characterization of A-to-I RNA editing hotspots in microRNAs across human cancers

Wang, Y., Xu, X., Yu, S., Jeong, K. J., Zhou, Z., Han, L., Tsang, Y. H., Li, J., Chen, H., Mangala, L. S., Yuan, Y., Eterovic, A. K., Lu, Y., Sood, A. K., Scott, K. L., Mills, G. B. & Liang, H., Jul 2017, In : Genome Research. 27, 7, p. 1112-1125 14 p.

Research output: Contribution to journalArticle

46 Scopus citations

Systematic Functional Annotation of Somatic Mutations in Cancer

Ng, P. K. S., Li, J., Jeong, K. J., Shao, S., Chen, H., Tsang, Y. H., Sengupta, S., Wang, Z., Bhavana, V. H., Tran, R., Soewito, S., Minussi, D. C., Moreno, D., Kong, K., Dogruluk, T., Lu, H., Gao, J., Tokheim, C., Zhou, D. C., Johnson, A. M. & 20 others, Zeng, J., Ip, C. K. M., Ju, Z., Wester, M., Yu, S., Li, Y., Vellano, C. P., Schultz, N., Karchin, R., Ding, L., Lu, Y., Cheung, L. W. T., Chen, K., Shaw, K. R., Meric-Bernstam, F., Scott, K. L., Yi, S., Sahni, N., Liang, H. & Mills, G., Mar 12 2018, In : Cancer Cell. 33, 3, p. 450-462.e10

Research output: Contribution to journalArticle

45 Scopus citations

The Genomic Landscape and Clinical Relevance of A-to-I RNA Editing in Human Cancers

Han, L., Diao, L., Yu, S., Xu, X., Li, J., Zhang, R., Yang, Y., Werner, H. M. J., Eterovic, A. K., Yuan, Y., Li, J., Nair, N., Minelli, R., Tsang, Y. H., Cheung, L. W. T., Jeong, K. J., Roszik, J., Ju, Z., Woodman, S. E., Lu, Y. & 4 others, Scott, K. L., Li, J. B., Mills, G. B. & Liang, H., Oct 12 2015, In : Cancer Cell. 28, 4, p. 515-528 14 p., 2143.

Research output: Contribution to journalArticle

168 Scopus citations
Editorial

Which path to follow? Utilizing proteomics to improve therapy choices for breast cancer patients

Blucher, A. S., Mills, G. B. & Tsang, Y. H., Jan 1 2020, (Accepted/In press) In : Expert Review of Proteomics.

Research output: Contribution to journalEditorial

Open Access