Xiaoquan Rao

Assistant Professor

  • 1141 Citations
  • 20 h-Index
20112019
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Research Output 2011 2019

  • 1141 Citations
  • 20 h-Index
  • 25 Article
  • 14 Review article
  • 1 Editorial
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Article
2019

Air pollution-derived particulate matter dysregulates hepatic Krebs cycle, glucose and lipid metabolism in mice

Reyes-Caballero, H., Rao, X., Sun, Q., Warmoes, M. O., Penghui, L., Sussan, T. E., Park, B., Fan, T. W. M., Maiseyeu, A., Rajagopalan, S., Girnun, G. D. & Biswal, S., Dec 1 2019, In : Scientific Reports. 9, 1, 17423.

Research output: Contribution to journalArticle

Open Access
Citric Acid Cycle
Particulate Matter
Air Pollution
Lipid Metabolism
Glucose
2 Citations (Scopus)

Alpha2B-Adrenergic Receptor Overexpression in the Brain Potentiate Air Pollution-induced Behavior and Blood Pressure Changes

Rao, X., Asico, L. D., Zanos, P., Mahabeleshwar, G. H., Singh Gangwar, R., Xia, C., Duan, L., Cisse, Y. M., Rengasamy, P., Jose, P. A., Gould, T. D., Nelson, R., Biswal, S., Chen, L. C., Zhong, J. & Rajagopalan, S., May 1 2019, In : Toxicological sciences : an official journal of the Society of Toxicology. 169, 1, p. 95-107 13 p.

Research output: Contribution to journalArticle

Blood pressure
Air Pollution
Air pollution
Adrenergic Receptors
Brain

Alpha2B-Adrenergic Receptor Regulates Neutrophil Recruitment in MSU-Induced Peritoneal Inflammation

Duan, L., Chen, J., Razavi, M., Wei, Y., Tao, Y., Rao, X. & Zhong, J., Jan 1 2019, In : Frontiers in immunology. 10, 1 p.

Research output: Contribution to journalArticle

Open Access
Neutrophil Infiltration
Uric Acid
Adrenergic Receptors
Inflammation
Gout
1 Citation (Scopus)

MRP14 enhances the ability of macrophage to recruit T cells and promotes obesity-induced insulin resistance

Xia, C., Razavi, M., Rao, X., Braunstein, Z., Mao, H., Toomey, A. C., Wang, Y., Simon, D. I., Zhao, S., Rajagopalan, S. & Zhong, J., Jan 1 2019, In : International Journal of Obesity.

Research output: Contribution to journalArticle

Insulin Resistance
Obesity
Macrophages
T-Lymphocytes
Proteins
1 Citation (Scopus)

Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathways

Rao, X., Zhao, S., Braunstein, Z., Mao, H., Razavi, M., Duan, L., Wei, Y., Toomey, A. C., Rajagopalan, S. & Zhong, J., Jan 1 2019, In : EBioMedicine.

Research output: Contribution to journalArticle

Open Access
Toll-Like Receptor 4
Macrophages
Up-Regulation
Monocytes
Atherosclerosis
2018
2 Citations (Scopus)

CITED2 restrains proinflammatory macrophage activation and response

Kim, G. D., Das, R., Rao, X., Zhong, J., Deiuliis, J. A., Ramirez-Bergeron, D. L., Rajagopalan, S. & Mahabeleshwar, G. H., Mar 1 2018, In : Molecular and Cellular Biology. 38, 5, e00452-17.

Research output: Contribution to journalArticle

Open Access
Macrophage Activation
Macrophages
PPAR gamma
Gene Expression
Hypoxia-Inducible Factor 1
1 Citation (Scopus)

Monocyte DPP4 expression in human atherosclerosis is associated with obesity and dyslipidemia

Rao, X., Deiuliis, J. A., Mihai, G., Varghese, J., Xia, C., Frieman, M. B., Sztalryd, C., Sun, X. J., Quon, M. J., Taylor, S. I., Ajagopalan, S. & Zhong, J., Jan 1 2018, In : Diabetes Care. 41, 1, p. e1-e3

Research output: Contribution to journalArticle

Open Access
Dyslipidemias
Monocytes
Atherosclerosis
Obesity
2016
11 Citations (Scopus)

Cardiovascular safety of dipeptidyl peptidase-4 inhibitors: Recent evidence on heart failure

Kankanala, S. R., Syed, R., Gong, Q., Ren, B., Rao, X. & Zhong, J., Jan 1 2016, In : American Journal of Translational Research. 8, 5, p. 2450-2458 9 p.

Research output: Contribution to journalArticle

Dipeptidyl-Peptidase IV Inhibitors
Heart Failure
Safety
Incretins
Publications
58 Citations (Scopus)

Extreme Air Pollution Conditions Adversely Affect Blood Pressure and Insulin Resistance: The Air Pollution and Cardiometabolic Disease Study

Brook, R. D., Sun, Z., Brook, J. R., Zhao, X., Ruan, Y., Yan, J., Mukherjee, B., Rao, X., Duan, F., Sun, L., Liang, R., Lian, H., Zhang, S., Fang, Q., Gu, D., Sun, Q., Fan, Z. & Rajagopalan, S., Jan 1 2016, In : Hypertension. 67, 1, p. 77-85 9 p.

Research output: Contribution to journalArticle

Open Access
Particulate Matter
Air Pollution
Soot
Insulin Resistance
Blood Pressure
5 Citations (Scopus)

IL-6 Inhibition Reduces STAT3 Activation and Enhances the Antitumor Effect of Carboplatin

Wang, Z. Y., Zhang, J. A., Wu, X. J., Liang, Y. F., Lu, Y. B., Gao, Y. C., Dai, Y. C., Yu, S. Y., Jia, Y., Fu, X. X., Rao, X., Xu, J. F. & Zhong, J., Jan 1 2016, In : Mediators of Inflammation. 2016, 8026494.

Research output: Contribution to journalArticle

Open Access
Carboplatin
Interleukin-6
Neoplasms
Colorectal Neoplasms
Tumor Microenvironment
11 Citations (Scopus)

Repeated ozone exposure exacerbates insulin resistance and activates innate immune response in genetically susceptible mice

Zhong, J., Allen, K., Rao, X., Ying, Z., Braunstein, Z., Kankanala, S. R., Xia, C., Wang, X., Bramble, L. A., Wagner, J. G., Lewandowski, R., Sun, Q., Harkema, J. R. & Rajagopalan, S., Jul 28 2016, In : Inhalation Toxicology. 28, 9, p. 383-392 10 p.

Research output: Contribution to journalArticle

Ozone
Innate Immunity
Insulin Resistance
Intra-Abdominal Fat
Insulin
2015
42 Citations (Scopus)

Air pollution as a risk factor for type 2 diabetes

Rao, X., Patel, P., Puett, R. & Rajagopalan, S., Jan 1 2015, In : Toxicological Sciences. 143, 2, p. 231-241 11 p., kfu250.

Research output: Contribution to journalArticle

Open Access
Air Pollution
Medical problems
Air pollution
Type 2 Diabetes Mellitus
Immune system
2014
64 Citations (Scopus)

Air pollution-mediated susceptibility to inflammation and insulin resistance: Influence of CCR2 pathways in mice

Liu, C., Xu, X., Bai, Y., Wang, T. Y., Rao, X., Wang, A., Sun, L., Ying, Z., Gushchina, L., Maiseyeu, A., Morishita, M., Sun, Q., Harkema, J. R. & Rajagopalan, S., Jan 1 2014, In : Environmental health perspectives. 122, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Open Access
CCR2 Receptors
Air Pollution
Insulin Resistance
Inflammation
Intra-Abdominal Fat
64 Citations (Scopus)

CD36-dependent 7-ketocholesterol accumulation in macrophages mediates progression of atherosclerosis in response to chronic air pollution exposure

Rao, X., Zhong, J., Maiseyeu, A., Gopalakrishnan, B., Villamena, F. A., Chen, L. C., Harkema, J. R., Sun, Q. & Rajagopalan, S., Jan 1 2014, In : Circulation research. 115, 9, p. 770-780 11 p.

Research output: Contribution to journalArticle

Open Access
Air Pollution
Atherosclerosis
Macrophages
Lipids
IDL Lipoproteins
25 Citations (Scopus)

MBD2 regulates T H 17 differentiation and experimental autoimmune encephalomyelitis by controlling the homeostasis of T-bet/Hlx axis

Zhong, J., Yu, Q., Yang, P., Rao, X., He, L., Fang, J., Tu, Y., Zhang, Z., Lai, Q., Zhang, S., Kuczma, M., Kraj, P., Xu, J. F., Gong, F., Zhou, J., Wen, L., Eizirik, D. L., Du, J., Wang, W. & Wang, C. Y., Jan 1 2014, In : Journal of Autoimmunity. 53, C, p. 95-104 10 p.

Research output: Contribution to journalArticle

Autoimmune Experimental Encephalomyelitis
Homeostasis
Epigenomics
Methylation
DNA Methylation
39 Citations (Scopus)

T-cell costimulation protects obesity-induced adipose inflammation and insulin resistance

Zhong, J., Rao, X., Braunstein, Z., Taylor, A., Narula, V., Hazey, J., Mikami, D., Needleman, B., Rutsky, J., Sun, Q., Deiuliis, J. A., Satoskar, A. R. & Rajagopalan, S., Apr 1 2014, In : Diabetes. 63, 4, p. 1289-1302 14 p.

Research output: Contribution to journalArticle

Open Access
Insulin Resistance
Obesity
Inflammation
T-Lymphocytes
Macrophages
2013
85 Citations (Scopus)

A potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammation

Zhong, J., Rao, X., Deiuliis, J., Braunstein, Z., Narula, V., Hazey, J., Mikami, D., Needleman, B., Satoskar, A. R. & Rajagopalan, S., Jan 1 2013, In : Diabetes. 62, 1, p. 149-157 9 p.

Research output: Contribution to journalArticle

Open Access
Abdominal Obesity
Dendritic Cells
Macrophages
Inflammation
Adenosine Deaminase
15 Citations (Scopus)

Exercise protects against diet-induced insulin resistance through downregulation of protein kinase Cβ in mice

Rao, X., Zhong, J., Xu, X., Jordan, B., Maurya, S., Braunstein, Z., Wang, T. Y., Huang, W., Aggarwal, S., Periasamy, M., Rajagopalan, S., Mehta, K. & Sun, Q., Dec 9 2013, In : PloS one. 8, 12, e81364.

Research output: Contribution to journalArticle

Open Access
protein kinase C
Nutrition
insulin resistance
protein kinases
Protein Kinases
10 Citations (Scopus)

SUMO1 regulates endothelial function by modulating the overall signals in favor of angiogenesis and homeostatic responses

Yang, P., Zhang, Y., Xu, J., Zhang, S., Yu, Q., Pang, J., Rao, X., Kuczma, M., Marrero, M. B., Fulton, D., Kraj, P., Su, Y. & Wang, C. Y., Jan 1 2013, In : American Journal of Translational Research. 5, 4, p. 427-440 14 p.

Research output: Contribution to journalArticle

Sumoylation
Ubiquitin
Endothelial cells
Swine
Endothelial Cells
2012
21 Citations (Scopus)

Effect of co-exposure to nickel and particulate matter on insulin resistance and mitochondrial dysfunction in a mouse model

Xu, X., Rao, X., Wang, T. Y., Jiang, S. Y., Ying, Z., Liu, C., Wang, A., Zhong, M., Deiuliis, J. A., Maiseyeu, A., Rajagopalan, S., Lippmann, M., Chen, L. C. & Sun, Q., Nov 5 2012, In : Particle and Fibre Toxicology. 9, 40.

Research output: Contribution to journalArticle

Open Access
Particulate Matter
Nickel
Insulin Resistance
Insulin
Toxicity
19 Citations (Scopus)

Effects of a Novel Pharmacologic Inhibitor of Myeloperoxidase in a Mouse Atherosclerosis Model

Liu, C., Desikan, R., Ying, Z., Gushchina, L., Kampfrath, T., Deiuliis, J., Wang, A., Xu, X., Zhong, J., Rao, X., Sun, Q., Maiseyeu, A., Parthasarathy, S. & Rajagopalan, S., Dec 10 2012, In : PloS one. 7, 12, e50767.

Research output: Contribution to journalArticle

Open Access
myeloperoxidase
atherosclerosis
Peroxidase
Atherosclerosis
mice
1 Citation (Scopus)

Elevated Th17 and IL-23 in hypertensive patients with acutly increased blood pressure

Wang, J., Chen, J., Chen, C., Huang, S., Rao, X. & Zhong, J., Sep 24 2012, In : American Journal of Immunology. 8, 2, p. 27-32 6 p.

Research output: Contribution to journalArticle

Interleukin-23
Interleukin-17
Blood Pressure
Healthy Volunteers
Hypertension
23 Citations (Scopus)

Protective Effects of Acyl-coA Thioesterase 1 on Diabetic Heart via PPARα/PGC1α Signaling

Yang, S., Chen, C., Wang, H., Rao, X., Wang, F., Duan, Q., Chen, F., Long, G., Gong, W., Zou, M. H. & Wang, D. W., Nov 30 2012, In : PloS one. 7, 11, e50376.

Research output: Contribution to journalArticle

Open Access
Peroxisome Proliferator-Activated Receptors
protective effect
heart
Diabetic Cardiomyopathies
cardiomyopathy
2011
59 Citations (Scopus)

Cytochrome P450 2J2 is highly expressed in hematologic malignant diseases and promotes tumor cell growth

Chen, C., Wei, X., Rao, X., Wu, J., Yang, S., Chen, F., Ma, D., Zhou, J., Dackor, R. T., Zeldin, D. C. & Wang, D. W., Feb 1 2011, In : Journal of Pharmacology and Experimental Therapeutics. 336, 2, p. 344-355 12 p.

Research output: Contribution to journalArticle

Hematologic Diseases
Cytochrome P-450 Enzyme System
Growth
Neoplasms
Heterografts
56 Citations (Scopus)

Loss of methyl-CpG-binding domain protein 2 enhances endothelial angiogenesis and protects mice against hind-limb ischemic injury

Rao, X., Zhong, J., Zhang, S., Zhang, Y., Yu, Q., Yang, P., Wang, M. H., Fulton, D. J., Shi, H., Dong, Z., Wang, D. & Wang, C. Y., Jun 28 2011, In : Circulation. 123, 25, p. 2964-2974 11 p.

Research output: Contribution to journalArticle

Open Access
Extremities
Nitric Oxide Synthase Type III
DNA Methylation
Wounds and Injuries
Vascular Endothelial Growth Factor Receptor-2