Xiaoquan Rao

Assistant Professor

  • 1335 Citations
  • 21 h-Index
20112019

Research output per year

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Research Output

  • 1335 Citations
  • 21 h-Index
  • 25 Article
  • 14 Review article
  • 1 Editorial
2019

Air pollution-derived particulate matter dysregulates hepatic Krebs cycle, glucose and lipid metabolism in mice

Reyes-Caballero, H., Rao, X., Sun, Q., Warmoes, M. O., Penghui, L., Sussan, T. E., Park, B., Fan, T. W. M., Maiseyeu, A., Rajagopalan, S., Girnun, G. D. & Biswal, S., Dec 1 2019, In : Scientific Reports. 9, 1, 17423.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Alpha2B-adrenergic receptor overexpression in the brain potentiate air pollution-induced behavior and blood pressure changes

Rao, X., Asico, L. D., Zanos, P., Mahabeleshwar, G. H., Gangwar, R. S., Xia, C., Duan, L., Cisse, Y. M., Rengasamy, P., Jose, P. A., Gould, T. D., Nelson, R., Biswal, S., Chen, L. C., Zhong, J. & Rajagopalan, S., Jan 1 2019, In : Toxicological Sciences. 169, 1, p. 95-107 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Alpha2b-adrenergic receptor regulates neutrophil recruitment in MSU-induced peritoneal inflammation

Duan, L., Chen, J., Razavi, M., Wei, Y., Tao, Y., Rao, X. & Zhong, J., 2019, In : Frontiers in immunology. 10, MAR, 501.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

MRP14 enhances the ability of macrophage to recruit T cells and promotes obesity-induced insulin resistance

Xia, C., Razavi, M., Rao, X., Braunstein, Z., Mao, H., Toomey, A. C., Wang, Y., Simon, D. I., Zhao, S., Rajagopalan, S. & Zhong, J., Dec 1 2019, In : International Journal of Obesity. 43, 12, p. 2434-2447 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathways

Rao, X., Zhao, S., Braunstein, Z., Mao, H., Razavi, M., Duan, L., Wei, Y., Toomey, A. C., Rajagopalan, S. & Zhong, J., Mar 2019, In : EBioMedicine. 41, p. 50-61 12 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Regulation of inflammation in autoimmune disease

Duan, L., Rao, X. & Sigdel, K. R., 2019, In : Journal of Immunology Research. 2019, 7403796.

Research output: Contribution to journalEditorial

Open Access
3 Scopus citations
2018

CITED2 restrains proinflammatory macrophage activation and response

Kim, G. D., Das, R., Rao, X., Zhong, J., Deiuliis, J. A., Ramirez-Bergeron, D. L., Rajagopalan, S. & Mahabeleshwar, G. H., Mar 1 2018, In : Molecular and Cellular Biology. 38, 5, e00452-17.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Dichotomous roles of co-stimulatory molecules in diabetes mellitus

Zhong, J. X., Chen, J., Rao, X. & Duan, L., 2018, In : Oncotarget. 9, 2, p. 2902-2911 10 p.

Research output: Contribution to journalReview article

Open Access

Effect of Particulate Matter Air Pollution on Cardiovascular Oxidative Stress Pathways

Rao, X., Zhong, J., Brook, R. D. & Rajagopalan, S., Mar 20 2018, In : Antioxidants and Redox Signaling. 28, 9, p. 797-818 22 p.

Research output: Contribution to journalReview article

40 Scopus citations

Monocyte DPP4 expression in human atherosclerosis is associated with obesity and dyslipidemia

Rao, X., Deiuliis, J. A., Mihai, G., Varghese, J., Xia, C., Frieman, M. B., Sztalryd, C., Sun, X. J., Quon, M. J., Taylor, S. I., Ajagopalan, S. & Zhong, J., Jan 1 2018, In : Diabetes care. 41, 1, p. e1-e3

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

S100 proteins as an important regulator of macrophage inflammation

Xia, C., Braunstein, Z., Toomey, A. C., Zhong, J. & Rao, X., Jan 5 2018, In : Frontiers in immunology. 8, JAN, 1908.

Research output: Contribution to journalReview article

Open Access
38 Scopus citations
2017

Airborne particulate matter induces nonallergic eosinophilic sinonasal inflammation in mice

Ramanathan, M., London, N. R., Tharakan, A., Surya, N., Sussan, T. E., Rao, X., Lin, S. Y., Toskala, E., Rajagopalan, S. & Biswal, S., Jul 1 2017, In : American journal of respiratory cell and molecular biology. 57, 1, p. 59-65 7 p.

Research output: Contribution to journalReview article

24 Scopus citations

DPP4 inhibitors and cardiovascular outcomes: safety on heart failure

Xia, C., Goud, A., D’Souza, J., Dahagam, C. H., Rao, X., Rajagopalan, S. & Zhong, J., May 1 2017, In : Heart Failure Reviews. 22, 3, p. 299-304 6 p.

Research output: Contribution to journalReview article

8 Scopus citations

Environmental stressors and cardio-metabolic disease: Part II-mechanistic insights

Münzel, T., Sørensen, M., Gori, T., Schmidt, F. P., Rao, X., Brook, F. R., Chen, L. C., Brook, R. D. & Rajagopalan, S., Feb 1 2017, In : European Heart Journal. 38, 8, p. 557-564 8 p.

Research output: Contribution to journalReview article

Open Access
105 Scopus citations

Environmental stressors and cardio-metabolic disease: Part I-epidemiologic evidence supporting a role for noise and air pollution and effects of mitigation strategies

Münzel, T., Sørensen, M., Gori, T., Schmidt, F. P., Rao, X., Brook, J., Chen, L. C., Brook, R. D. & Rajagopalan, S., Feb 1 2017, In : European Heart Journal. 38, 8, p. 550-556 7 p.

Research output: Contribution to journalReview article

Open Access
110 Scopus citations

Role of incretin axis in inflammatory bowel disease

Duan, L., Rao, X., Braunstein, Z., Toomey, A. C. & Zhong, J., Dec 6 2017, In : Frontiers in immunology. 8, DEC, 1734.

Research output: Contribution to journalReview article

Open Access
11 Scopus citations

Role of T Lymphocytes in Type 2 Diabetes and Diabetes-Associated Inflammation

Xia, C., Rao, X. & Zhong, J., 2017, In : Journal of Diabetes Research. 2017, 6494795.

Research output: Contribution to journalReview article

Open Access
49 Scopus citations

The regulatory role of DPP4 in atherosclerotic disease

Duan, L., Rao, X., Xia, C., Rajagopalan, S. & Zhong, J., Jan 1 2017, In : Cardiovascular Diabetology. 16, 1, 76.

Research output: Contribution to journalReview article

Open Access
9 Scopus citations
2016

Cardiovascular safety of dipeptidyl peptidase-4 inhibitors: Recent evidence on heart failure

Kankanala, S. R., Syed, R., Gong, Q., Ren, B., Rao, X. & Zhong, J., Jan 1 2016, In : American Journal of Translational Research. 8, 5, p. 2450-2458 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Extreme Air Pollution Conditions Adversely Affect Blood Pressure and Insulin Resistance: The Air Pollution and Cardiometabolic Disease Study

Brook, R. D., Sun, Z., Brook, J. R., Zhao, X., Ruan, Y., Yan, J., Mukherjee, B., Rao, X., Duan, F., Sun, L., Liang, R., Lian, H., Zhang, S., Fang, Q., Gu, D., Sun, Q., Fan, Z. & Rajagopalan, S., Jan 1 2016, In : Hypertension. 67, 1, p. 77-85 9 p.

Research output: Contribution to journalArticle

Open Access
63 Scopus citations

IL-6 Inhibition Reduces STAT3 Activation and Enhances the Antitumor Effect of Carboplatin

Wang, Z. Y., Zhang, J. A., Wu, X. J., Liang, Y. F., Lu, Y. B., Gao, Y. C., Dai, Y. C., Yu, S. Y., Jia, Y., Fu, X. X., Rao, X., Xu, J. F. & Zhong, J., 2016, In : Mediators of Inflammation. 2016, 8026494.

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Repeated ozone exposure exacerbates insulin resistance and activates innate immune response in genetically susceptible mice

Zhong, J., Allen, K., Rao, X., Ying, Z., Braunstein, Z., Kankanala, S. R., Xia, C., Wang, X., Bramble, L. A., Wagner, J. G., Lewandowski, R., Sun, Q., Harkema, J. R. & Rajagopalan, S., Jul 28 2016, In : Inhalation Toxicology. 28, 9, p. 383-392 10 p.

Research output: Contribution to journalArticle

14 Scopus citations
2015

Air pollution as a risk factor for type 2 diabetes

Rao, X., Patel, P., Puett, R. & Rajagopalan, S., Feb 1 2015, In : Toxicological Sciences. 143, 2, p. 231-241 11 p., kfu250.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

Ambient air pollution: An emerging risk factor for diabetes mellitus

Rao, X., Montresor-Lopez, J., Puett, R., Rajagopalan, S. & Brook, R. D., Jun 1 2015, In : Current diabetes reports. 15, 6, p. 1-11 11 p.

Research output: Contribution to journalReview article

50 Scopus citations
2014

Air pollution-mediated susceptibility to inflammation and insulin resistance: Influence of CCR2 pathways in mice

Liu, C., Xu, X., Bai, Y., Wang, T. Y., Rao, X., Wang, A., Sun, L., Ying, Z., Gushchina, L., Maiseyeu, A., Morishita, M., Sun, Q., Harkema, J. R. & Rajagopalan, S., Jan 2014, In : Environmental health perspectives. 122, 1, p. 17-26 10 p.

Research output: Contribution to journalArticle

Open Access
81 Scopus citations

CD36-dependent 7-ketocholesterol accumulation in macrophages mediates progression of atherosclerosis in response to chronic air pollution exposure

Rao, X., Zhong, J., Maiseyeu, A., Gopalakrishnan, B., Villamena, F. A., Chen, L. C., Harkema, J. R., Sun, Q. & Rajagopalan, S., Jan 1 2014, In : Circulation research. 115, 9, p. 770-780 11 p.

Research output: Contribution to journalArticle

Open Access
70 Scopus citations

MBD2 regulates TH17 differentiation and experimental autoimmune encephalomyelitis by controlling the homeostasis of T-bet/Hlx axis

Zhong, J., Yu, Q., Yang, P., Rao, X., He, L., Fang, J., Tu, Y., Zhang, Z., Lai, Q., Zhang, S., Kuczma, M., Kraj, P., Xu, J. F., Gong, F., Zhou, J., Wen, L., Eizirik, D. L., Du, J., Wang, W. & Wang, C. Y., 2014, In : Journal of Autoimmunity. 53, C, p. 95-104 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

T-cell costimulation protects obesity-induced adipose inflammation and insulin resistance

Zhong, J., Rao, X., Braunstein, Z., Taylor, A., Narula, V., Hazey, J., Mikami, D., Needleman, B., Rutsky, J., Sun, Q., Deiuliis, J. A., Satoskar, A. R. & Rajagopalan, S., Apr 1 2014, In : Diabetes. 63, 4, p. 1289-1302 14 p.

Research output: Contribution to journalArticle

Open Access
41 Scopus citations

The heterogenic properties of monocytes/macrophages and neutrophils in inflammatory response in diabetes

Rao, X., Zhong, J. & Sun, Q., Oct 29 2014, In : Life Sciences. 116, 2, p. 59-66 8 p.

Research output: Contribution to journalReview article

31 Scopus citations
2013

An emerging role of dipeptidyl peptidase 4 (DPP4) beyond glucose control: Potential implications in cardiovascular disease

Zhong, J., Rao, X. & Rajagopalan, S., Feb 1 2013, In : Atherosclerosis. 226, 2, p. 305-314 10 p.

Research output: Contribution to journalReview article

136 Scopus citations

A potential role for dendritic cell/macrophage-expressing DPP4 in obesity-induced visceral inflammation

Zhong, J., Rao, X., Deiuliis, J., Braunstein, Z., Narula, V., Hazey, J., Mikami, D., Needleman, B., Satoskar, A. R. & Rajagopalan, S., Jan 1 2013, In : Diabetes. 62, 1, p. 149-157 9 p.

Research output: Contribution to journalArticle

Open Access
94 Scopus citations

Exercise protects against diet-induced insulin resistance through downregulation of protein kinase Cβ in mice

Rao, X., Zhong, J., Xu, X., Jordan, B., Maurya, S., Braunstein, Z., Wang, T. Y., Huang, W., Aggarwal, S., Periasamy, M., Rajagopalan, S., Mehta, K. & Sun, Q., Dec 9 2013, In : PloS one. 8, 12, e81364.

Research output: Contribution to journalArticle

Open Access
17 Scopus citations

SUMO1 regulates endothelial function by modulating the overall signals in favor of angiogenesis and homeostatic responses

Yang, P., Zhang, Y., Xu, J., Zhang, S., Yu, Q., Pang, J., Rao, X., Kuczma, M., Marrero, M. B., Fulton, D., Kraj, P., Su, Y. & Wang, C. Y., Jan 1 2013, In : American Journal of Translational Research. 5, 4, p. 427-440 14 p.

Research output: Contribution to journalArticle

10 Scopus citations
2012

Effect of co-exposure to nickel and particulate matter on insulin resistance and mitochondrial dysfunction in a mouse model

Xu, X., Rao, X., Wang, T. Y., Jiang, S. Y., Ying, Z., Liu, C., Wang, A., Zhong, M., Deiuliis, J. A., Maiseyeu, A., Rajagopalan, S., Lippmann, M., Chen, L. C. & Sun, Q., Nov 5 2012, In : Particle and Fibre Toxicology. 9, 40.

Research output: Contribution to journalArticle

Open Access
21 Scopus citations

Effects of a Novel Pharmacologic Inhibitor of Myeloperoxidase in a Mouse Atherosclerosis Model

Liu, C., Desikan, R., Ying, Z., Gushchina, L., Kampfrath, T., Deiuliis, J., Wang, A., Xu, X., Zhong, J., Rao, X., Sun, Q., Maiseyeu, A., Parthasarathy, S. & Rajagopalan, S., Dec 10 2012, In : PloS one. 7, 12, e50767.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

Elevated Th17 and IL-23 in hypertensive patients with acutly increased blood pressure

Wang, J., Chen, J., Chen, C., Huang, S., Rao, X. & Zhong, J., Sep 24 2012, In : American Journal of Immunology. 8, 2, p. 27-32 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Protective Effects of Acyl-coA Thioesterase 1 on Diabetic Heart via PPARα/PGC1α Signaling

Yang, S., Chen, C., Wang, H., Rao, X., Wang, F., Duan, Q., Chen, F., Long, G., Gong, W., Zou, M. H. & Wang, D. W., Nov 30 2012, In : PloS one. 7, 11, e50376.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

The role of endoplasmic reticulum stress in autoimmune-mediated beta-cell destruction in type 1 diabetes

Zhong, J., Rao, X., Xu, J. F., Yang, P. & Wang, C. Y., 2012, In : Experimental Diabetes Research. 2012, 238980.

Research output: Contribution to journalReview article

Open Access
23 Scopus citations
2011

Cytochrome P450 2J2 is highly expressed in hematologic malignant diseases and promotes tumor cell growth

Chen, C., Wei, X., Rao, X., Wu, J., Yang, S., Chen, F., Ma, D., Zhou, J., Dackor, R. T., Zeldin, D. C. & Wang, D. W., Feb 2011, In : Journal of Pharmacology and Experimental Therapeutics. 336, 2, p. 344-355 12 p.

Research output: Contribution to journalArticle

63 Scopus citations

Loss of methyl-CpG-binding domain protein 2 enhances endothelial angiogenesis and protects mice against hind-limb ischemic injury

Rao, X., Zhong, J., Zhang, S., Zhang, Y., Yu, Q., Yang, P., Wang, M. H., Fulton, D. J., Shi, H., Dong, Z., Wang, D. & Wang, C. Y., Jun 28 2011, In : Circulation. 123, 25, p. 2964-2974 11 p.

Research output: Contribution to journalArticle

Open Access
59 Scopus citations