William Rooney

Professor

  • 4865 Citations
  • 44 h-Index
1988 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

2020

Imaging Mechanisms of Disease Progression in Multiple Sclerosis: Beyond Brain Atrophy

NAIMS Cooperative, May 1 2020, In : Journal of Neuroimaging. 30, 3, p. 251-266 16 p.

Research output: Contribution to journalReview article

1 Scopus citations

Modeling disease trajectory in Duchenne muscular dystrophy

Rooney, W. D., Berlow, Y. A., Triplett, W. T., Forbes, S. C., Willcocks, R. J., Wang, D. J., Arpan, I., Arora, H., Senesac, C., Lott, D. J., Tennekoon, G., Finkel, R., Russman, B. S., Finanger, E. L., Chakraborty, S., O'Brien, E., Moloney, B., Barnard, A., Sweeney, H. L., Daniels, M. J. & 2 others, Walter, G. A. & Vandenborne, K., Apr 14 2020, In : Neurology. 94, 15, p. E1622-E1633

Research output: Contribution to journalArticle

MR biomarkers predict clinical function in Duchenne muscular dystrophy

Barnard, A. M., Willcocks, R. J., Triplett, W. T., Forbes, S. C., Daniels, M. J., Chakraborty, S., Lott, D. J., Senesac, C. R., Finanger, E. L., Harrington, A. T., Tennekoon, G., Arora, H., Wang, D. J., Sweeney, H. L., Rooney, W. D., Walter, G. A. & Vandenborne, K., Mar 3 2020, In : Neurology. 94, 9, p. e897-e909

Research output: Contribution to journalArticle

3 Scopus citations

Observation of Reduced Homeostatic Metabolic Activity and/or Coupling in White Matter Aging

Anderson, V. C., Tagge, I. J., Li, X., Quinn, J. F., Kaye, J. A., Bourdette, D. N., Spain, R. I., Riccelli, L. P., Sammi, M. K., Springer, C. S. & Rooney, W. D., 2020, (Accepted/In press) In : Journal of Neuroimaging.

Research output: Contribution to journalArticle

Upper and lower extremities in Duchenne muscular dystrophy evaluated with quantitative MRI and proton MR spectroscopy in a multicenter cohort

Forbes, S. C., Arora, H., Willcocks, R. J., Triplett, W. T., Rooney, W. D., Barnard, A. M., Alabasi, U., Wang, D. J., Lott, D. J., Senesac, C. R., Harrington, A. T., Finanger, E. L., Tennekoon, G. I., Brandsema, J., Daniels, M. J., Lee Sweeney, H., Walter, G. A. & Vandenborne, K., Jun 2020, In : RADIOLOGY. 295, 3, p. 616-625 10 p.

Research output: Contribution to journalArticle

2019

Combined iron oxide nanoparticle ferumoxytol and gadolinium contrast enhanced MRI define glioblastoma pseudoprogression

Barajas, R. F., Hamilton, B. E., Schwartz, D., Mcconnell, H. L., Pettersson, D. R., Horvath, A., Szidonya, L., Varallyay, C. G., Firkins, J., Jaboin, J. J., Kubicky, C. D., Raslan, A. M., Dogan, A., Cetas, J. S., Ciporen, J., Han, S. J., Ambady, P., Muldoon, L. L., Woltjer, R., Rooney, W. D. & 1 others, Neuwelt, E. A., Mar 18 2019, In : Neuro-Oncology. 21, 4, p. 517-526 10 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
4 Scopus citations

Imaging outcome measures of neuroprotection and repair in MS: A consensus statement from NAIMS

Oh, J., Ontaneda, D., Azevedo, C., Klawiter, E. C., Absinta, M., Arnold, D. L., Bakshi, R., Calabresi, P. A., Crainiceanu, C., Dewey, B., Freeman, L., Gauthier, S., Henry, R., Inglese, M., Kolind, S., Li, D. K. B., Mainero, C., Menon, R. S., Nair, G., Narayanan, S. & 15 others, Nelson, F., Pelletier, D., Rauscher, A., Rooney, W., Sati, P., Schwartz, D., Shinohara, R. T., Tagge, I., Traboulsee, A., Wang, Y., Yoo, Y., Yousry, T., Zhang, Y., Sicotte, N. L. & Reich, D. S., Mar 12 2019, In : Neurology. 92, 11, p. 519-533 15 p.

Research output: Contribution to journalReview article

9 Scopus citations

Multisite reliability and repeatability of an advanced brain MRI protocol

on behalf of the NAIMS Cooperative, Jan 1 2019, (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

7 Scopus citations
2018

An automated statistical technique for counting distinct multiple sclerosis lesions

Dworkin, J. D., Linn, K. A., Oguz, I., Fleishman, G. M., Bakshi, R., Nair, G., Calabresi, P. A., Henry, R. G., Oh, J., Papinutto, N., Pelletier, D., Rooney, W., Stern, W., Sicotte, N. L., Reich, D. S. & Shinohara, R. T., Apr 1 2018, In : American Journal of Neuroradiology. 39, 4, p. 626-633 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Baseline NAWM structural integrity and CBF predict periventricular WMH expansion over time

Promjunyakul, N. O., Dodge, H. H., Lahna, D., Boespflug, E. L., Kaye, J. A., Rooney, W. D. & Silbert, L. C., Jun 12 2018, In : Neurology. 90, 24, p. e2107-e2118

Research output: Contribution to journalArticle

11 Scopus citations

Cerebral blood volume mapping with ferumoxytol in dynamic susceptibility contrast perfusion MRI: Comparison to standard of care

Varallyay, C. G., Nesbit, E., Horvath, A., Varallyay, P., Fu, R. R., Gahramanov, S., Muldoon, L., Li, X., Rooney, W. & Neuwelt, E., Jan 1 2018, (Accepted/In press) In : Journal of Magnetic Resonance Imaging.

Research output: Contribution to journalArticle

2 Scopus citations

Gradient nonlinearity effects on upper cervical spinal cord area measurement from 3D T 1 -weighted brain MRI acquisitions

for the North American Imaging in Multiple Sclerosis Cooperative(NAIMS), Mar 2018, In : Magnetic Resonance in Medicine. 79, 3, p. 1595-1601 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
12 Scopus citations

Multi-parametric T2* magnetic resonance fingerprinting using variable echo times

Wyatt, C. R., Smith, T., Sammi, M., Rooney, W. & Guimaraes, A., Sep 1 2018, In : NMR in Biomedicine. 31, 9, e3951.

Research output: Contribution to journalArticle

8 Scopus citations

Nigrosome 1 absence in de novo Parkinson disease

Brodsky, M., Lahna, D., Pollock, J., Pettersson, D., Grinstead, J. & Rooney, W., Mar 13 2018, In : Neurology. 90, 11, p. 522-523 2 p.

Research output: Contribution to journalShort survey

2 Scopus citations

Skeletal muscle magnetic resonance biomarkers correlate with function and sentinel events in Duchenne muscular dystrophy

Barnard, A. M., Willcocks, R. J., Finanger, E. L., Daniels, M. J., Triplett, W. T., Rooney, W. D., Lott, D. J., Forbes, S. C., Wang, D. J., Senesac, C. R., Harrington, A. T., Finkel, R. S., Russman, B. S., Byrne, B. J., Tennekoon, G. I., Walter, G. A., Sweeney, H. L. & Vandenborne, K., Mar 2018, In : PloS one. 13, 3, e0194283.

Research output: Contribution to journalArticle

18 Scopus citations

Two-year longitudinal changes in lower limb strength and its relation to loss in function in a large cohort of patients with duchenne muscular dystrophy

Batra, A., Harrington, A., Lott, D. J., Willcocks, R., Senesac, C. R., McGehee, W., Xu, D., Mathur, S., Daniels, M. J., Rooney, W. D., Forbes, S. C., Triplett, W., Deol, J. K., Arpan, I., Bendixen, R., Finkel, R., Finanger, E., Tennekoon, G., Byrne, B., Russman, B. & 3 others, Sweeney, H. L., Walter, G. & Vandenborne, K., Oct 1 2018, In : American Journal of Physical Medicine and Rehabilitation. 97, 10, p. 734-740 7 p.

Research output: Contribution to journalArticle

2017

Current and potential imaging applications of ferumoxytol for magnetic resonance imaging

Toth, G. B., Varallyay, C. G., Horvath, A., Bashir, M. R., Choyke, P. L., Daldrup-Link, H. E., Dosa, E., Finn, J. P., Gahramanov, S., Harisinghani, M., Macdougall, I., Neuwelt, A., Vasanawala, S. S., Ambady, P., Barajas, R., Cetas, J. S., Ciporen, J., DeLoughery, T. J., Doolittle, N. D., Fu, R. & 13 others, Grinstead, J., Guimaraes, A. R., Hamilton, B. E., Li, X., McConnell, H. L., Muldoon, L. L., Nesbit, G., Netto, J. P., Petterson, D., Rooney, W. D., Schwartz, D., Szidonya, L. & Neuwelt, E. A., Jul 2017, In : Kidney International. 92, 1, p. 47-66 20 p.

Research output: Contribution to journalReview article

73 Scopus citations

Pseudo-extravasation rate constant of dynamic susceptibility contrast-MRI determined from pharmacokinetic first principles

Li, X., Varallyay, C. G., Gahramanov, S., Fu, R. R., Rooney, W. & Neuwelt, E., 2017, (Accepted/In press) In : NMR in Biomedicine.

Research output: Contribution to journalArticle

The NAIMS cooperative pilot project: Design, implementation and future directions

on behalf of the NAIMS Cooperative Steering Committee, Oct 1 2017, (Accepted/In press) In : Multiple Sclerosis Journal.

Research output: Contribution to journalArticle

3 Scopus citations

Volumetric analysis from a harmonized multisite brain MRI study of a single subject with multiple sclerosis

Shinohara, R. T., Oh, J., Nair, G., Calabresi, P. A., Davatzikos, C., Doshi, J., Henry, R. G., Kim, G., Linn, K. A., Papinutto, N., Pelletier, D., Pham, D. L., Reich, D. S., Rooney, W., Roy, S., Stern, W., Tummala, S., Yousuf, F., Zhu, A., Sicotte, N. L. & 1 others, Bakshi, R., Aug 1 2017, In : American Journal of Neuroradiology. 38, 8, p. 1501-1509 9 p.

Research output: Contribution to journalArticle

35 Scopus citations
2016
21 Scopus citations

Corrections to Comorbidities of epilepsy: Current concepts and future perspectives. [Lancet Neurol, 15, (2015), 106-15]

Forbes, S. C., Willcocks, R. J., Rooney, W., Walter, G. A. & Vandenborne, K., Jan 1 2016, In : The Lancet Neurology. 15, 1, p. 28 1 p.

Research output: Contribution to journalComment/debate

Duchenne regulatory science consortium meeting on disease progression modeling for duchenne muscular dystrophy

members of the Duchenne Regulatory Science Consortium, Imaging-DMD Consortium and the CINRG Investigators, 2016, In : PLoS Currents. 8, MuscularDystrophy

Research output: Contribution to journalArticle

Immunopathology of Japanese macaque encephalomyelitis is similar to multiple sclerosis

Blair, T. C., Manoharan, M., Rawlings-Rhea, S. D., Tagge, I., Kohama, S. G., Hollister-Smith, J., Ferguson, B., Woltjer, R. L., Frederick, M. C., Pollaro, J., Rooney, W. D., Sherman, L. S., Bourdette, D. N. & Wong, S. W., Feb 15 2016, In : Journal of Neuroimmunology. 291, p. 1-10 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Magnetic resonance imaging of the proximal upper extremity musculature in boys with Duchenne muscular dystrophy

Willcocks, R. J., Triplett, W. T., Forbes, S. C., Arora, H., Senesac, C. R., Lott, D. J., Nicholson, T. R., Rooney, W., Walter, G. A. & Vandenborne, K., Oct 24 2016, (Accepted/In press) In : Journal of Neurology. p. 1-8 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Multicenter prospective longitudinal study of magnetic resonance biomarkers in a large duchenne muscular dystrophy cohort

Willcocks, R. J., Rooney, W., Triplett, W. T., Forbes, S. C., Lott, D. J., Senesac, C. R., Daniels, M. J., Wang, D. J., Harrington, A. T., Tennekoon, G. I., Russman, B. S., Finanger, E., Byrne, B. J., Finkel, R. S., Walter, G. A., Sweeney, H. L. & Vandenborne, K., 2016, (Accepted/In press) In : Annals of Neurology.

Research output: Contribution to journalArticle

64 Scopus citations
19 Scopus citations

Spatio-temporal patterns of demyelination and remyelination in the cuprizone mouse model

Tagge, I., O'Connor, A., Chaudhary, P., Pollaro, J., Berlow, Y., Chalupsky, M., Bourdette, D., Woltjer, R., Johnson, M. & Rooney, W., Apr 2016, In : PloS one. 11, 4, e0152480.

Research output: Contribution to journalArticle

26 Scopus citations
99 Scopus citations

Toward 20 T magnetic resonance for human brain studies: opportunities for discovery and neuroscience rationale

Budinger, T. F., Bird, M. D., Frydman, L., Long, J. R., Mareci, T. H., Rooney, W., Rosen, B., Schenck, J. F., Schepkin, V. D., Sherry, A. D., Sodickson, D. K., Springer, C. J., Thulborn, K. R., Uğurbil, K. & Wald, L. L., May 18 2016, (Accepted/In press) In : Magnetic Resonance Materials in Physics, Biology and Medicine. p. 1-23 23 p.

Research output: Contribution to journalArticle

32 Scopus citations
2015

Characterizing the white matter hyperintensity penumbra with cerebral blood flow measures

Promjunyakul, N., Lahna, D., Kaye, J. A., Dodge, H. H., Erten-Lyons, D., Rooney, W. D. & Silbert, L. C., Jun 8 2015, In : NeuroImage: Clinical. 8, p. 224-229 6 p.

Research output: Contribution to journalArticle

46 Scopus citations

Erratum: Myelin water mapping by spatially regularized longitudinal relaxographic imaging at high magnetic fields (Magnetic Resonance in Medicine (2014) 71 (375-387))

Labadie, C., Lee, J. H., Rooney, W. D., Jarchow, S., Aubert-Frécon, M., Springer, C. S. & Möller, H. E., Nov 2015, In : Magnetic Resonance in Medicine. 74, 5, 1 p.

Research output: Contribution to journalComment/debate

29 Scopus citations

MRI quantifies neuromuscular disease progression

Forbes, S. C., Willcocks, R. J., Rooney, W., Walter, G. A. & Vandenborne, K., 2015, (Accepted/In press) In : The Lancet Neurology.

Research output: Contribution to journalArticle

14 Scopus citations

Polyphenon E, non-futile at neuroprotection in multiple sclerosis but unpredictably hepatotoxic: Phase I single group and phase II randomized placebo-controlled studies

Lovera, J., Ramos, A., Devier, D., Garrison, V., Kovner, B., Reza, T., Koop, D., Rooney, W., Foundas, A. & Bourdette, D., Nov 15 2015, In : Journal of the Neurological Sciences. 358, 1-2, p. 46-52 7 p.

Research output: Contribution to journalArticle

27 Scopus citations
2014

Chemical shift-based MRI to measure fat fractions in dystrophic skeletal muscle

Triplett, W. T., Baligand, C., Forbes, S. C., Willcocks, R. J., Lott, D. J., DeVos, S., Pollaro, J., Rooney, W. D., Sweeney, H. L., Bönnemann, C. G., Wang, D. J., Vandenborne, K. & Walter, G. A., Jul 2014, In : Magnetic Resonance in Medicine. 72, 1, p. 8-19 12 p.

Research output: Contribution to journalArticle

50 Scopus citations

Examination of effects of corticosteroids on skeletal muscles of boys with DMD using MRI and MRS

Arpan, I., Willcocks, R. J., Forbes, S. C., Finkel, R. S., Lott, D. J., Rooney, W. D., Triplett, W. T., Senesac, C. R., Daniels, M. J., Byrne, B. J., Finanger, E. L., Russman, B. S., Wang, D. J., Tennekoon, G. I., Walter, G. A., Sweeney, H. L. & Vandenborne, K., Sep 1 2014, In : Neurology. 83, 11, p. 974-980 7 p.

Research output: Contribution to journalArticle

73 Scopus citations

Intratumor mapping of intracellular water lifetime: Metabolic images of breast cancer?

Springer, C. S., Li, X., Tudorica, L. A., Oh, K. Y., Roy, N., Chui, S. Y. C., Naik, A. M., Holtorf, M. L., Afzal, A., Rooney, W. D. & Huang, W., Jul 2014, In : NMR in biomedicine. 27, 7, p. 760-773 14 p.

Research output: Contribution to journalArticle

42 Scopus citations

Longitudinal relaxographic imaging of white matter hyperintensities in the elderly

Anderson, V., Obayashi, J. T., Kaye, J., Quinn, J., Berryhill, P., Riccelli, L. P., Peterson, D. & Rooney, W., 2014, In : Fluids and Barriers of the CNS. 11, 1, 24.

Research output: Contribution to journalArticle

7 Scopus citations

Loss of pons-to-hypothalamic white matter tracks in brainstem obesity

Purnell, J. Q., Lahna, D. L., Samuels, M. H., Rooney, W. D. & Hoffman, W. F., Dec 11 2014, In : International Journal of Obesity. 38, 12, p. 1573-1577 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Magnetic resonance imaging and spectroscopy assessment of lower extremity skeletal muscles in boys with duchenne muscular dystrophy: A multicenter cross sectional study

Forbes, S. C., Willcocks, R. J., Triplett, W. T., Rooney, W. D., Lott, D. J., Wang, D. J., Pollaro, J., Senesac, C. R., Daniels, M. J., Finkel, R. S., Russman, B. S., Byrne, B. J., Finanger, E. L., Tennekoon, G. I., Walter, G. A., Sweeney, H. L. & Vandenborne, K., Sep 2014, In : PloS one. 9, 9, 0106435.

Research output: Contribution to journalArticle

66 Scopus citations

Markers of cochlear inflammation using MRI

Floc'H, J. L., Tan, W., Telang, R. S., Vlajkovic, S. M., Nuttall, A., Rooney, W. D., Pontré, B. & Thorne, P. R., Jan 1 2014, In : Journal of Magnetic Resonance Imaging. 39, 1, p. 150-161 12 p.

Research output: Contribution to journalArticle

16 Scopus citations

Myelin water mapping by spatially regularized longitudinal relaxographic imaging at high magnetic fields

Labadie, C., Lee, J. H., Rooney, W. D., Jarchow, S., Aubert-Frécon, M., Springer, C. S. & Möller, H. E., Jan 1 2014, In : Magnetic Resonance in Medicine. 71, 1, p. 375-387 13 p.

Research output: Contribution to journalArticle

56 Scopus citations
12 Scopus citations
2013

Feasibility of shutter-speed DCE-MRI for improved prostate cancer detection

Li, X., Priest, R. A., Woodward, W. J., Tagge, I. J., Siddiqui, F., Huang, W., Rooney, W. D., Beer, T. M., Garzotto, M. G. & Springer, C. S., Jan 1 2013, In : Magnetic Resonance in Medicine. 69, 1, p. 171-178 8 p.

Research output: Contribution to journalArticle

24 Scopus citations
63 Scopus citations

Intrahepatic lipid, not visceral or muscle fat, is correlated with insulin resistance in older, female rhesus macaques

Chu, M. P., Klopfenstein, B. J., Krisky, C. M., Urbanski, H. F., Rooney, W. D., Kohama, S. G. & Purnell, J. Q., Oct 1 2013, In : Obesity. 21, 10, p. 2021-2028 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
97 Scopus citations