William Fleming

Professor

  • 3173 Citations
  • 30 h-Index
1982 …2021
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Hematopoietic Stem Cells Medicine & Life Sciences
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Stem Cells Medicine & Life Sciences
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Projects 1988 2021

Rcor1 Regulates Myelomonocytic Progenitor Cell Fate

Fleming, W.

National Institutes of Health

7/15/165/31/21

Project: Research projectResearch Project

Monocytes
Stem Cells
Hematopoiesis
Hematopoietic Stem Cells
Granulocytes

MOLECULAR GENETICS OF FANCONI ANEMIA

Olson, S., Bagby, G., Moses, R., Grompe, M., D'Andrea, A. D., Postlethwait, J. H., D'Andrea, A. D. & Fleming, W.

National Institutes of Health

7/1/945/31/21

Project: Research projectResearch Program Projects

Fanconi Anemia
Cytogenetics
Genes
Fanconi Anemia Complementation Group Proteins
Bone Marrow

X-ray biological irradiator for small animal and cell irradiation

Fleming, W.

National Institutes of Health

4/1/113/31/12

Project: Research projectBiomedical Research Support Shared Instrumentation Grants

research projects
X-radiation
irradiation
cesium
animals

Stem Cell-Based Therapies for Mitigation of Acute Radiation Syndromes

Fleming, W., Sellers, R., Kurland, I. J., Guha, C. & Chen, E. I.

National Institutes of Health

8/1/107/31/16

Project: Research projectResearch Program--Cooperative Agreements

Hematopoietic System
Regeneration
Endothelial Cells
Bone Marrow
Radiation

Endothelial Potential of Bone Marrow Derived Progenitors

Fleming, W.

National Institutes of Health

4/1/053/31/10

Project: Research projectResearch Project

Bone Marrow
Endothelial Cells
Vascular Endothelium
Hematopoietic Stem Cells
Bone Marrow Cells

Research Output 1982 2017

  • 3173 Citations
  • 30 h-Index
  • 57 Article
  • 1 Review article
2 Citations

The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model

Janghorban, M., Langer, E. M., Wang, X., Zachman, D., Daniel, C. J., Hooper, J., Fleming, W. H., Agarwal, A. & Sears, R. C., Nov 1 2017, In : PLoS One. 12, 11, e0188910

Research output: Contribution to journalArticle

Tumor Suppressor Proteins
Protein Phosphatase 2
phosphoprotein phosphatase
Phosphatases
Stem cells
9 Citations

Intestinal microbiota-derived metabolomic blood plasma markers for prior radiation injury

Broin, P., Vaitheesvaran, B., Saha, S., Hartil, K., Chen, E. I., Goldman, D., Fleming, W. H., Kurland, I. J., Guha, C. & Golden, A., 2015, In : International Journal of Radiation Oncology Biology Physics. 91, 2, p. 360-367 8 p.

Research output: Contribution to journalArticle

radiation injuries
blood plasma
Radiation Injuries
Metabolomics
metabolites
4 Citations

The corepressor Rcor1 is essential for normal myeloerythroid lineage differentiation

Yao, H., Goldman, D. C., Fan, G., Mandel, G. & Fleming, W. H., Nov 1 2015, In : Stem Cells. 33, 11, p. 3304-3314 11 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Lymphoid Progenitor Cells
Monocytes
B-Lymphocytes
Hematopoietic Stem Cells
5 Citations

The triterpenoid RTA 408 is a robust mitigator of hematopoietic acute radiation syndrome in mice

Goldman, D. C., Alexeev, V., Lash, E., Guha, C., Rodeck, U. & Fleming, W. H., Mar 1 2015, In : Radiation Research. 183, 3, p. 338-344 7 p.

Research output: Contribution to journalArticle

Acute Radiation Syndrome
bone marrow
radiation dosage
mice
stem cells
12 Citations

Corepressor Rcor1 is essential for murine erythropoiesis

Yao, H., Goldman, D. C., Nechiporuk, T., Kawane, S., McWeeney, S. K., Tyner, J. W., Fan, G., Kerenyi, M. A., Orkin, S. H., Fleming, W. H. & Mandel, G., May 15 2014, In : Blood. 123, 20, p. 3175-3184 10 p.

Research output: Contribution to journalArticle

Co-Repressor Proteins
Erythropoiesis
Genes
Erythroblasts
Colony-Stimulating Factor Receptors