Vivek Unni

Associate Professor

  • 3222 Citations
  • 14 h-Index
19982021
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Synucleins Medicine & Life Sciences
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Projects 2010 2021

Synucleins
Cell Death
Pathology
Neurons
Parkinsonian Disorders
Synucleins
alpha-Synuclein
Parkinson Disease
Movement Disorders
General Hospitals

Research Output 1998 2016

  • 3222 Citations
  • 14 h-Index
  • 15 Article
40 Citations (Scopus)

G2019s-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons

Volpicelli-Daley, L. A., Abdelmotilib, H., Liu, Z., Stoyka, L., Daher, J. P. L., Milnerwood, A. J., Unni, V., Hirst, W. D., Yue, Z., Zhao, H. T., Fraser, K., Kennedy, R. E. & West, A. B., Jul 13 2016, In : Journal of Neuroscience. 36, 28, p. 7415-7427 13 p.

Research output: Contribution to journalArticle

Synucleins
Neurons
Phosphotransferases
Parkinson Disease
Antisense Oligonucleotides
14 Citations (Scopus)

Curcumin treatment improves motor behavior in α-synuclein transgenic mice

Spinelli, K. J., Osterberg, V. R., Meshul, C. K., Soumyanath, A. & Unni, V., Jun 2 2015, In : PLoS One. 10, 6, e0128510.

Research output: Contribution to journalArticle

Synucleins
Curcumin
curcumin
Transgenic Mice
genetically modified organisms
93 Citations (Scopus)

Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

Legati, A., Giovannini, D., Nicolas, G., López-Sánchez, U., Quintáns, B., Oliveira, J. R. M., Sears, R. L., Ramos, E. M., Spiteri, E., Sobrido, M. J., Carracedo, Á., Castro-Fernández, C., Cubizolle, S., Fogel, B. L., Goizet, C., Jen, J. C., Kirdlarp, S., Lang, A. E., Miedzybrodzka, Z., Mitarnun, W. & 21 othersPaucar, M., Paulson, H., Pariente, J., Richard, A. C., Salins, N. S., Simpson, S. A., Striano, P., Svenningsson, P., Tison, F., Unni, V., Vanakker, O., Wessels, M. W., Wetchaphanphesat, S., Yang, M., Boller, F., Campion, D., Hannequin, D., Sitbon, M., Geschwind, D. H., Battini, J. L. & Coppola, G., May 27 2015, In : Nature Genetics. 47, 6, p. 579-581 3 p.

Research output: Contribution to journalArticle

Phosphates
Mutation
Brain
Proto-Oncogene Proteins c-sis
Platelet-Derived Growth Factor beta Receptor
70 Citations (Scopus)

Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism

Osterberg, V., Spinelli, K., Weston, L., Luk, K., Woltjer, R. R. & Unni, V., Mar 3 2015, In : Cell Reports. 10, 8, p. 1252-1260 9 p.

Research output: Contribution to journalArticle

Bearings (structural)
alpha-Synuclein
Parkinsonian Disorders
Neurons
Agglomeration
58 Citations (Scopus)

Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease

Spinelli, K. J., Taylor, J. K., Osterberg, V. R., Churchill, M. J., Pollock, E., Moore, C., Meshul, C. K. & Unni, V., 2014, In : Journal of Neuroscience. 34, 6, p. 2037-2050 14 p.

Research output: Contribution to journalArticle

Synucleins
alpha-Synuclein
Parkinson Disease
Fluorescence Recovery After Photobleaching
Presynaptic Terminals