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The regulation of alpha-synuclein and neurodegeneration in Parkinson's Disease
Project: Research project
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Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner
Boutros, S. W., Krenik, D., Holden, S., Unni, V. K. & Raber, J., 2022, In: Oncotarget. 13, 1, p. 198-213 16 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Phosphorylation of the aggregate-forming protein alpha-synuclein on serine-129 inhibits its DNA-bending properties
Dent, S. E., King, D. P., Osterberg, V. R., Adams, E. K., Mackiewicz, M. R., Weissman, T. A. & Unni, V. K., Feb 1 2022, In: Journal of Biological Chemistry. 298, 2, 101552.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Effects of Alpha-Synuclein Targeted Antisense Oligonucleotides on Lewy Body-Like Pathology and Behavioral Disturbances Induced by Injections of Pre-Formed Fibrils in the Mouse Motor Cortex
Boutros, S. W., Raber, J. & Unni, V. K., 2021, In: Journal of Parkinson's Disease. 11, 3, p. 1091-1115 25 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Genetic deletion of Polo-like kinase 2 reduces alpha-synuclein serine-129 phosphorylation in presynaptic terminals but not Lewy bodies
Weston, L. J., Stackhouse, T. L., Spinelli, K. J., Boutros, S. W., Rose, E. P., Osterberg, V. R., Luk, K. C., Raber, J., Weissman, T. A. & Unni, V. K., Jan 1 2021, In: Journal of Biological Chemistry. 296, 100273.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
In vivo aggregation of presynaptic alpha-synuclein is not influenced by its phosphorylation at serine-129
Weston, L. J., Cook, Z. T., Stackhouse, T. L., Sal, M. K., Schultz, B. I., Tobias, Z. J. C., Osterberg, V. R., Brockway, N. L., Pizano, S., Glover, G., Weissman, T. A. & Unni, V. K., May 2021, In: Neurobiology of Disease. 152, 105291.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations