Vivek Unni

Assistant Professor

  • 2754 Citations
  • 12 h-Index
19982021

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  • 13 Similar Profiles
alpha-Synuclein Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences
Neurons Medicine & Life Sciences
Autophagy Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Proteasome Endopeptidase Complex Medicine & Life Sciences
Proteins Medicine & Life Sciences
Brain Medicine & Life Sciences

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Projects 2010 2021

Mechanisms of neuronal cell death in synucleinopathies

Unni, V.

National Institutes of Health

4/1/163/31/21

Project: Research projectResearch Scientist Development Award - Research

Cell Death
Pathology
Neurons
Synucleins
Electrons

The regulation of alpha-synuclein and neurodegeneration in Parkinson's Disease

Unni, V.

National Institutes of Health

8/1/105/31/15

Project: Research projectClinical Investigator Award (CIA)

alpha-Synuclein
Parkinson Disease
Synucleins
Proteins
Research

Research Output 1998 2016

  • 2754 Citations
  • 12 h-Index
  • 16 Article
12 Citations

G2019s-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons

Volpicelli-Daley, L. A., Abdelmotilib, H., Liu, Z., Stoyka, L., Daher, J. P. L., Milnerwood, A. J., Unni, V. K., Hirst, W. D., Yue, Z., Zhao, H. T., Fraser, K., Kennedy, R. E. & West, A. B. Jul 13 2016 In : Journal of Neuroscience. 36, 28, p. 7415-7427 13 p.

Research output: Research - peer-reviewArticle

alpha-Synuclein
Neurons
Phosphotransferases
Parkinson Disease
Antisense Oligonucleotides
8 Citations

Curcumin treatment improves motor behavior in α-synuclein transgenic mice

Spinelli, K. J., Osterberg, V. R., Meshul, C. K., Soumyanath, A. & Unni, V. K. Jun 2 2015 In : PLoS One. 10, 6, e0128510

Research output: Research - peer-reviewArticle

curcumin
genetically modified organisms
mice
alpha-Synuclein
Curcumin
47 Citations

Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

Legati, A. , Giovannini, D. , Nicolas, G. , López-Sánchez, U. , Quintáns, B. , Oliveira, J. R. M. , Sears, R. L. , Ramos, E. M. , Spiteri, E. , Sobrido, M. J. , Carracedo, Á. , Castro-Fernández, C. , Cubizolle, S. , Fogel, B. L. , Goizet, C. , Jen, J. C. , Kirdlarp, S. , Lang, A. E. , Miedzybrodzka, Z. , Mitarnun, W. & 21 others Paucar, M., Paulson, H., Pariente, J., Richard, A. C., Salins, N. S., Simpson, S. A., Striano, P., Svenningsson, P., Tison, F., Unni, V. K., Vanakker, O., Wessels, M. W., Wetchaphanphesat, S., Yang, M., Boller, F., Campion, D., Hannequin, D., Sitbon, M., Geschwind, D. H., Battini, J. L. & Coppola, G. May 27 2015 In : Nature Genetics. 47, 6, p. 579-581 3 p.

Research output: Research - peer-reviewArticle

Phosphates
Mutation
Brain
Proto-Oncogene Proteins c-sis
Platelet-Derived Growth Factor beta Receptor
45 Citations

Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism

Osterberg, V., Spinelli, K., Weston, L., Luk, K., Woltjer, R. & Unni, V. Mar 3 2015 In : Cell Reports. 10, 8, p. 1252-1260 9 p.

Research output: Research - peer-reviewArticle

Bearings (structural)
alpha-Synuclein
Neurons
Agglomeration
Parkinsonian Disorders
42 Citations

Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease

Spinelli, K. J., Taylor, J. K., Osterberg, V. R., Churchill, M. J., Pollock, E., Moore, C., Meshul, C. K. & Unni, V. K. 2014 In : Journal of Neuroscience. 34, 6, p. 2037-2050 14 p.

Research output: Research - peer-reviewArticle

alpha-Synuclein
Parkinson Disease
Proteins
Fluorescence Recovery After Photobleaching
Presynaptic Terminals