Projects per year
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- 7 Similar Profiles
alpha-Synuclein
Medicine & Life Sciences
Parkinson Disease
Medicine & Life Sciences
Neurons
Medicine & Life Sciences
Autophagy
Medicine & Life Sciences
Ubiquitin
Medicine & Life Sciences
Proteasome Endopeptidase Complex
Medicine & Life Sciences
Presynaptic Terminals
Medicine & Life Sciences
Synaptogyrins
Medicine & Life Sciences
Network
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Projects 2010 2021
Mechanisms of neuronal cell death in synucleinopathies
4/1/16 → 3/31/21
Project: Research project › Research Scientist Development Award - Research
Synucleins
Cell Death
Pathology
Neurons
Parkinsonian Disorders
The regulation of alpha-synuclein and neurodegeneration in Parkinson's Disease
8/1/10 → 5/31/15
Project: Research project › Clinical Investigator Award (CIA)
Synucleins
alpha-Synuclein
Parkinson Disease
Movement Disorders
General Hospitals
Research Output 1998 2016
- 3156 Citations
- 13 h-Index
- 15 Article
36
Citations
G2019s-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons
Volpicelli-Daley, L. A., Abdelmotilib, H., Liu, Z., Stoyka, L., Daher, J. P. L., Milnerwood, A. J., Unni, V., Hirst, W. D., Yue, Z., Zhao, H. T., Fraser, K., Kennedy, R. E. & West, A. B., Jul 13 2016, In : Journal of Neuroscience. 36, 28, p. 7415-7427 13 p.Research output: Contribution to journal › Article
alpha-Synuclein
Neurons
Phosphotransferases
Parkinson Disease
Antisense Oligonucleotides
13
Citations
Curcumin treatment improves motor behavior in α-synuclein transgenic mice
Spinelli, K. J., Osterberg, V. R., Meshul, C. K., Soumyanath, A. & Unni, V., Jun 2 2015, In : PLoS One. 10, 6, e0128510.Research output: Contribution to journal › Article
alpha-Synuclein
Curcumin
curcumin
Transgenic Mice
genetically modified organisms
84
Citations
Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export
Legati, A., Giovannini, D., Nicolas, G., López-Sánchez, U., Quintáns, B., Oliveira, J. R. M., Sears, R. L., Ramos, E. M., Spiteri, E., Sobrido, M. J., Carracedo, Á., Castro-Fernández, C., Cubizolle, S., Fogel, B. L., Goizet, C., Jen, J. C., Kirdlarp, S., Lang, A. E., Miedzybrodzka, Z., Mitarnun, W. & 21 others, May 27 2015, In : Nature Genetics. 47, 6, p. 579-581 3 p.Research output: Contribution to journal › Article
Phosphates
Mutation
Brain
Proto-Oncogene Proteins c-sis
Platelet-Derived Growth Factor beta Receptor
66
Citations
Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism
Osterberg, V., Spinelli, K., Weston, L., Luk, K., Woltjer, R. R. & Unni, V., Mar 3 2015, In : Cell Reports. 10, 8, p. 1252-1260 9 p.Research output: Contribution to journal › Article
Bearings (structural)
alpha-Synuclein
Parkinsonian Disorders
Neurons
Agglomeration
57
Citations
Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease
Spinelli, K. J., Taylor, J. K., Osterberg, V. R., Churchill, M. J., Pollock, E., Moore, C., Meshul, C. K. & Unni, V., 2014, In : Journal of Neuroscience. 34, 6, p. 2037-2050 14 p.Research output: Contribution to journal › Article
alpha-Synuclein
Parkinson Disease
Fluorescence Recovery After Photobleaching
Presynaptic Terminals
Synucleins