Vivek Unni

Associate Professor

  • 3102 Citations
  • 13 h-Index
19982021
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Projects 2010 2021

Mechanisms of neuronal cell death in synucleinopathies

Unni, V.

National Institutes of Health

4/1/163/31/21

Project: Research projectResearch Scientist Development Award - Research

Synucleins
Cell Death
Pathology
Neurons
Parkinsonian Disorders

The regulation of alpha-synuclein and neurodegeneration in Parkinson's Disease

Unni, V.

National Institutes of Health

8/1/105/31/15

Project: Research projectClinical Investigator Award (CIA)

Synucleins
alpha-Synuclein
Parkinson Disease
Movement Disorders
General Hospitals

Research Output 1998 2016

  • 3102 Citations
  • 13 h-Index
  • 15 Article
33 Citations

G2019s-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons

Volpicelli-Daley, L. A., Abdelmotilib, H., Liu, Z., Stoyka, L., Daher, J. P. L., Milnerwood, A. J., Unni, V. K., Hirst, W. D., Yue, Z., Zhao, H. T., Fraser, K., Kennedy, R. E. & West, A. B., Jul 13 2016, In : Journal of Neuroscience. 36, 28, p. 7415-7427 13 p.

Research output: Contribution to journalArticle

alpha-Synuclein
Neurons
Phosphotransferases
Parkinson Disease
Antisense Oligonucleotides
12 Citations

Curcumin treatment improves motor behavior in α-synuclein transgenic mice

Spinelli, K. J., Osterberg, V. R., Meshul, C. K., Soumyanath, A. & Unni, V. K., Jun 2 2015, In : PLoS One. 10, 6, e0128510.

Research output: Contribution to journalArticle

alpha-Synuclein
Curcumin
curcumin
Transgenic Mice
genetically modified organisms
77 Citations

Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

Legati, A., Giovannini, D., Nicolas, G., López-Sánchez, U., Quintáns, B., Oliveira, J. R. M., Sears, R. L., Ramos, E. M., Spiteri, E., Sobrido, M. J., Carracedo, Á., Castro-Fernández, C., Cubizolle, S., Fogel, B. L., Goizet, C., Jen, J. C., Kirdlarp, S., Lang, A. E., Miedzybrodzka, Z., Mitarnun, W. & 21 othersPaucar, M., Paulson, H., Pariente, J., Richard, A. C., Salins, N. S., Simpson, S. A., Striano, P., Svenningsson, P., Tison, F., Unni, V. K., Vanakker, O., Wessels, M. W., Wetchaphanphesat, S., Yang, M., Boller, F., Campion, D., Hannequin, D., Sitbon, M., Geschwind, D. H., Battini, J. L. & Coppola, G., May 27 2015, In : Nature Genetics. 47, 6, p. 579-581 3 p.

Research output: Contribution to journalArticle

Phosphates
Mutation
Brain
Proto-Oncogene Proteins c-sis
Platelet-Derived Growth Factor beta Receptor
62 Citations

Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism

Osterberg, V., Spinelli, K., Weston, L., Luk, K., Woltjer, R. & Unni, V., Mar 3 2015, In : Cell Reports. 10, 8, p. 1252-1260 9 p.

Research output: Contribution to journalArticle

Bearings (structural)
alpha-Synuclein
Parkinsonian Disorders
Neurons
Agglomeration
54 Citations

Presynaptic alpha-synuclein aggregation in a mouse model of Parkinson's disease

Spinelli, K. J., Taylor, J. K., Osterberg, V. R., Churchill, M. J., Pollock, E., Moore, C., Meshul, C. K. & Unni, V. K., 2014, In : Journal of Neuroscience. 34, 6, p. 2037-2050 14 p.

Research output: Contribution to journalArticle

alpha-Synuclein
Parkinson Disease
Fluorescence Recovery After Photobleaching
Presynaptic Terminals
Synucleins