Vivek Unni

Associate Professor

  • 3380 Citations
  • 14 h-Index
19982021
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  • 12 Similar Profiles
Synucleins Medicine & Life Sciences
alpha-Synuclein Medicine & Life Sciences
Parkinson Disease Medicine & Life Sciences
Neurons Medicine & Life Sciences
Autophagy Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Proteasome Endopeptidase Complex Medicine & Life Sciences
Synaptogyrins Medicine & Life Sciences

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Projects 2010 2021

Synucleins
Cell Death
Pathology
Neurons
Parkinsonian Disorders
Synucleins
alpha-Synuclein
Parkinson Disease
Movement Disorders
General Hospitals

Research Output 1998 2019

  • 3380 Citations
  • 14 h-Index
  • 17 Article
1 Citation (Scopus)

Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders

Schaser, A. J., Osterberg, V. R., Dent, S. E., Stackhouse, T. L., Wakeham, C. M., Boutros, S. W., Weston, L. J., Owen, N., Weissman, T. A., Luna, E., Raber, J., Luk, K. C., McCullough, A., Woltjer, R. R. & Unni, V., Dec 1 2019, In : Scientific Reports. 9, 1, 10919.

Research output: Contribution to journalArticle

Open Access
Lewy Bodies
alpha-Synuclein
DNA-Binding Proteins
DNA Repair
DNA Damage
1 Citation (Scopus)

Multicolor lineage tracing using in vivo time-lapse imaging reveals coordinated death of clonally related cells in the developing vertebrate brain

Brockway, N. L., Cook, Z. T., O'Gallagher, M. J., Tobias, Z. J. C., Gedi, M., Carey, K. M., Unni, V., Pan, Y. A., Metz, M. R. & Weissman, T. A., Jan 1 2019, In : Developmental Biology.

Research output: Contribution to journalArticle

Open Access
Time-Lapse Imaging
Vertebrates
Clone Cells
Brain
Cell Nucleus Division
50 Citations (Scopus)

G2019s-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons

Volpicelli-Daley, L. A., Abdelmotilib, H., Liu, Z., Stoyka, L., Daher, J. P. L., Milnerwood, A. J., Unni, V., Hirst, W. D., Yue, Z., Zhao, H. T., Fraser, K., Kennedy, R. E. & West, A. B., Jul 13 2016, In : Journal of Neuroscience. 36, 28, p. 7415-7427 13 p.

Research output: Contribution to journalArticle

Synucleins
Neurons
Phosphotransferases
Parkinson Disease
Antisense Oligonucleotides
15 Citations (Scopus)

Curcumin treatment improves motor behavior in α-synuclein transgenic mice

Spinelli, K. J., Osterberg, V. R., Meshul, C. K., Soumyanath, A. & Unni, V., Jun 2 2015, In : PLoS One. 10, 6, e0128510.

Research output: Contribution to journalArticle

Synucleins
Curcumin
curcumin
Transgenic Mice
genetically modified organisms
110 Citations (Scopus)

Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

Legati, A., Giovannini, D., Nicolas, G., López-Sánchez, U., Quintáns, B., Oliveira, J. R. M., Sears, R. L., Ramos, E. M., Spiteri, E., Sobrido, M. J., Carracedo, Á., Castro-Fernández, C., Cubizolle, S., Fogel, B. L., Goizet, C., Jen, J. C., Kirdlarp, S., Lang, A. E., Miedzybrodzka, Z., Mitarnun, W. & 21 others, Paucar, M., Paulson, H., Pariente, J., Richard, A. C., Salins, N. S., Simpson, S. A., Striano, P., Svenningsson, P., Tison, F., Unni, V., Vanakker, O., Wessels, M. W., Wetchaphanphesat, S., Yang, M., Boller, F., Campion, D., Hannequin, D., Sitbon, M., Geschwind, D. H., Battini, J. L. & Coppola, G., May 27 2015, In : Nature Genetics. 47, 6, p. 579-581 3 p.

Research output: Contribution to journalArticle

Phosphates
Mutation
Brain
Proto-Oncogene Proteins c-sis
Platelet-Derived Growth Factor beta Receptor