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Thomas (Tom) Shearer

Professor

  • 4953 Citations
  • 39 h-Index
1967 …2017
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  • 5 Similar Profiles
Calpain Medicine & Life Sciences
Lenses Medicine & Life Sciences
Crystallins Medicine & Life Sciences
Cataract Medicine & Life Sciences
Selenious Acid Medicine & Life Sciences
Proteolysis Medicine & Life Sciences
Selenium Medicine & Life Sciences
Calcium Medicine & Life Sciences

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Projects 1981 2007

CALCIUM ACTIVATED PROTEASE IN CATARACT FORMATION

Shearer, T. (. & Tootell, R.

National Institutes of Health

9/30/86 → …

Project: Research project

Calpain
Cataract
Lenses
Rodentia
Crystallins

BIOMARKERS FOR TOTAL BODY BURDEN OF FLUORIDE

Shearer, T. (. & Lampi, K.

National Institutes of Health

9/1/03 → 8/31/07

Project: Research project

Body Burden
Fluorides
Biomarkers
Fluoridation
Health

OLYMPUS BHTU CLINICAL LABORATORY RESEARCH MICROSCOPE

Shearer, T. (.

National Institutes of Health

8/1/87 → 7/31/88

Project: Research project

TRANSMISSION ELECTRON MICROSCOPE FACILITY

Shearer, T. (., Smith, J. & Landis, D.

National Institutes of Health

3/1/83 → 2/28/95

Project: Research project

apprentice
Research Personnel
minority
Students
Financial Management

MECHANISM OF SELENIUM INDUCED CATARACT

Shearer, T. (.

National Institutes of Health

9/30/81 → 12/31/04

Project: Research project

Selenium
Cataract
Selenious Acid
Crystallins
Lenses

Research Output 1967 2017

  • 4953 Citations
  • 39 h-Index
  • 197 Article
  • 1 Conference contribution

Contribution of calpain and caspases to cell death in cultured monkey RPE cells

Nakajima, E., Hammond, K. B., Hirata, M., Shearer, T. T. & Azuma, M., Oct 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 12, p. 5412-5420 9 p.

Research output: Contribution to journal › Article

Calpain
Caspases
Haplorhini
Cell Death
Cultured Cells
3 Citations (Scopus)

In Silico Ocular Pharmacokinetic Modeling: Delivery of Topical FK962 to Retina

Mori, A., Yabuta, C., Kishimoto, Y., Kozai, S., Ohtori, A., Shearer, T. T. & Azuma, M., Sep 1 2017, In : Journal of Ocular Pharmacology and Therapeutics. 33, 7, p. 556-566 11 p.

Research output: Contribution to journal › Article

Computer Simulation
Retina
Pharmacokinetics
Choroid
Ophthalmic Solutions
1 Citation (Scopus)

FK962 induces neurite outgrowth in cultured monkey trigeminal ganglion cells

Nakajima, E., Walkup, R. D., Shearer, T. T. & Azuma, M., Oct 24 2016, (Accepted/In press) In : Graefe's Archive for Clinical and Experimental Ophthalmology. p. 1-6 6 p.

Research output: Contribution to journal › Article

Trigeminal Ganglion
Glial Cell Line-Derived Neurotrophic Factor
Haplorhini
Neurites
Wound Healing
1 Citation (Scopus)

Selecting fuchs patients for drug trials involving endothelial cell proliferation

Shearer, T. T., Chamberlain, W., Fujii, A. & Azuma, M., Nov 1 2016, In : European Journal of Ophthalmology. 26, 6, p. 536-539 4 p.

Research output: Contribution to journal › Article

Fuchs' Endothelial Dystrophy
Endothelial Cells
Cell Proliferation
Cell Count
Pharmaceutical Preparations
11 Citations (Scopus)

Galectin-3 enhances extracellular matrix associations and wound healing in monkey corneal epithelium

Fujii, A., Shearer, T. T. & Azuma, M., Aug 1 2015, In : Experimental Eye Research. 137, p. 71-78 8 p.

Research output: Contribution to journal › Article

Galectin 3
Corneal Epithelium
Wound Healing
Haplorhini
Extracellular Matrix