• 1483 Citations
  • 18 h-Index
1982 …2018
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Research Output 1982 2018

  • 1483 Citations
  • 18 h-Index
  • 46 Article
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Article

1-(2-pyrimidinyl)piperazine antagonizes GABA-activated currents in cultured spinal neurones of the rat

Smith, S. & Hughes, D., Jul 31 1989, In : Brain Research. 493, 2, p. 366-367 2 p.

Research output: Contribution to journalArticle

Buspirone
gamma-Aminobutyric Acid
Flurazepam
Aminobutyrates
Neurons

15th Annual Spring Brain Conference, March 10-13, 2004, summary report

Anstrom, K., Bergles, D., Bradley, K., Cao, Y., Cestnick, L., Lee, S., Piedras-Rentería, E., Savoie, K., Smith, S. & Woolsey, T. A., Jun 2004, In : Somatosensory and Motor Research. 21, 2, p. 137-143 7 p.

Research output: Contribution to journalArticle

Neurophysiology
Brain
358 Citations (Scopus)

Ablation of P/Q-type Ca2+ channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the α(1A)-subunit

Jun, K., Piedras-Rentería, E. S., Smith, S., Wheeler, D. B., Lee, S. B., Lee, T. G., Chin, H., Adams, M. E., Scheller, R. H., Tsien, R. W. & Shin, H. S., Dec 21 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 26, p. 15245-15250 6 p.

Research output: Contribution to journalArticle

Dystonia
Ataxia
Synaptic Transmission
Purkinje Cells
Migraine Disorders
39 Citations (Scopus)

Baclofen and gamma-hydroxybutyrate withdrawal

LeTourneau, J. L., Hagg, D. & Smith, S., Jun 2008, In : Neurocritical Care. 8, 3, p. 430-433 4 p.

Research output: Contribution to journalArticle

Sodium Oxybate
Baclofen
Delirium
Tremor
Benzodiazepines

Bleeding from the gastrointestinal tract during prolonged ventilation

Smith, S., Bihari, J., Zandstra, D. F. & Stoutenbeek, C. P., Jun 1995, In : Intensive Care Medicine. 21, 6, p. 543-544 2 p.

Research output: Contribution to journalArticle

Anti-Ulcer Agents
Gastrointestinal Hemorrhage
Artificial Respiration
Ventilation
Gastrointestinal Tract
4 Citations (Scopus)

Caesium ions: A glycine-activated channel agonist in rat spinal cord neurones grown in cell culture

Smith, S. & McBurney, R. N., 1989, In : British Journal of Pharmacology. 96, 4, p. 940-948 9 p.

Research output: Contribution to journalArticle

Cesium
Glycine
Spinal Cord
Cell Culture Techniques
Ions
15 Citations (Scopus)

Caesium ions activate chloride channels in rat cultured spinal cord neurones.

Hughes, D., McBurney, R. N., Smith, S. & Zorec, R., Nov 1 1987, In : The Journal of physiology. 392, 1, p. 231-251 21 p.

Research output: Contribution to journalArticle

Cesium
Chloride Channels
Spinal Cord
Neurons
Ions
11 Citations (Scopus)

Calcium dependence of spontaneous neurotransmitter release

Williams, C. L. & Smith, S., 2017, (Accepted/In press) In : Journal of Neuroscience Research.

Research output: Contribution to journalArticle

Synapses
Neurotransmitter Agents
Calcium
Calcium-Sensing Receptors
28 Citations (Scopus)

Calcium regulation of spontaneous and asynchronous neurotransmitter release

Smith, S., Chen, W., Vyleta, N. P., Williams, C., Lee, C. H., Phillips, C. & Andresen, M., Sep 2012, In : Cell Calcium. 52, 3-4, p. 226-233 8 p.

Research output: Contribution to journalArticle

Synapses
Neurotransmitter Agents
Calcium
Transient Receptor Potential Channels
Calcium-Sensing Receptors
9 Citations (Scopus)

Calcium-sensing receptor: A high-affinity presynaptic target for aminoglycoside-induced weakness

Harnett, M. T., Chen, W. & Smith, S., Oct 2009, In : Neuropharmacology. 57, 5-6, p. 502-505 4 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Aminoglycosides
Calcium Channels
Inhibitory Concentration 50
Cations
18 Citations (Scopus)

Calcium-sensing receptor: A key target for extracellular calcium signaling in neurons

Jones, B. L. & Smith, S., Mar 30 2016, In : Frontiers in Physiology. 7, MAR, 116.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Calcium Signaling
Calcium
Neurons
Nerve Tissue
38 Citations (Scopus)

Calcium-sensing receptor activation depresses synaptic transmission

Phillips, C. G., Harnett, M. T., Chen, W. & Smith, S., Nov 12 2008, In : Journal of Neuroscience. 28, 46, p. 12062-12070 9 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Synaptic Transmission
Spermidine
Carisoprodol
Synapses
32 Citations (Scopus)

Cerebral blood flow is proportional to cardiac index in patients with septic shock

Smith, S., Padayachee, S., Modaresi, K. B., Smithies, M. N. & Bihari, D. J., Sep 1998, In : Journal of Critical Care. 13, 3, p. 104-109 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Septic Shock
Extremities
Doppler Ultrasonography
Regional Blood Flow
4 Citations (Scopus)

Choice of crystalloid and mortality in sepsis-all in the timing? To the editor

Jones, B. L. & Smith, S., 2014, In : Critical Care Medicine. 42, 12, p. e796

Research output: Contribution to journalArticle

Isotonic Solutions
Fluid Therapy
Hospital Mortality
Critical Illness
Sepsis
29 Citations (Scopus)

Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABA

Williams, C., Chen, W., Lee, C. H., Yaeger, D., Vyleta, N. P. & Smith, S., Sep 2012, In : Nature Neuroscience. 15, 9, p. 1195-1197 3 p.

Research output: Contribution to journalArticle

Calcium Channels
Synapses
gamma-Aminobutyric Acid
Action Potentials
Neurotransmitter Agents
14 Citations (Scopus)

Colorimetric enzymatic measurement of serum total 3α-hydroxy bile acid concentrations without extraction

Qureshi, M. Y., Smith, S. & Murphy, G. M., 1984, In : Journal of Clinical Pathology. 37, 3, p. 317-320 4 p.

Research output: Contribution to journalArticle

Hydroxy Acids
Enzyme Assays
Bile Acids and Salts
Serum
Sensitivity and Specificity
31 Citations (Scopus)

Conductance states activated by glycine and GABA in rat cultured spinal neurones

Smith, S., Zorec, R. & McBurney, R. N., Apr 1989, In : The Journal of Membrane Biology. 108, 1, p. 45-52 8 p.

Research output: Contribution to journalArticle

Glycine
gamma-Aminobutyric Acid
Neurons
Chlorides
Spinal Cord
4 Citations (Scopus)

Crystal violet reactions of coagulase negative staphylococci

Freeman, R., Burdess, D. & Smith, S., 1994, In : Journal of Clinical Pathology. 47, 3, p. 283-285 3 p.

Research output: Contribution to journalArticle

Gentian Violet
Coagulase
Staphylococcus
Staphylococcus saprophyticus
Bacteriophages
10 Citations (Scopus)

Distinct actions of voltage-activated Ca2+ channel block on spontaneous release at excitatory and inhibitory central synapses

Tsintsadze, T., Williams, C. L., Weingarten, D. J., Von Gersdorff, H. & Smith, S., Apr 19 2017, In : Journal of Neuroscience. 37, 16, p. 4301-4310 10 p.

Research output: Contribution to journalArticle

Synapses
Calcium Channels
Calcium Channel Blockers
Synaptic Transmission
Brain Stem
Critical Illness
Intensive Care Units
Central Nervous System
Drug Overdose
Neurologic Examination
1 Citation (Scopus)

Extravascular lung water as a predictor of mortality in acute respiratory distress syndrome

Smith, S. & Phillips, C. R., Jul 2008, In : Critical Care Medicine. 36, 7, p. 2221-2222 2 p.

Research output: Contribution to journalArticle

Extravascular Lung Water
Adult Respiratory Distress Syndrome
Mortality
143 Citations (Scopus)
Extravascular Lung Water
Adult Respiratory Distress Syndrome
Sepsis
Body Weight
Lung Injury
12 Citations (Scopus)

Fast inhibition of glutamate-activated currents by caffeine

Vyleta, N. P. & Smith, S., Sep 10 2008, In : PLoS One. 3, 9, e3155.

Research output: Contribution to journalArticle

caffeine
Caffeine
glutamates
Glutamic Acid
Excitatory Postsynaptic Potentials

Glucose variance in ICU patients receiving insulin infusions

Smith, S. & Hagg, D., May 2008, In : Chest. 133, 5, p. 1288 1 p.

Research output: Contribution to journalArticle

Insulin
Glucose
1 Citation (Scopus)
Brain Hypoxia-Ischemia
Calcium-Sensing Receptors
Intracranial Vasospasm
Magnesium Sulfate
Calcium Channel Blockers
8 Citations (Scopus)

Measurement of conjugated and unconjugated serum bile acid concentrations using 3alpha-hydroxysteroid dehydrogenase

Smith, S., Myszor, M., Setchell, K. D. R. & Murphy, G. M., 1983, In : Journal of Clinical Pathology. 36, 2, p. 235-236 2 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Membrane capacitance changes induced by thrombin and calcium in single endothelial cells cultured from human umbilical vein

Carter, T. D., Zupancic, G., Smith, S., Wheeler-Jones, C. & Ogden, D., Dec 15 1998, In : Journal of Physiology. 513, 3, p. 845-855 11 p.

Research output: Contribution to journalArticle

Human Umbilical Vein Endothelial Cells
Thrombin
Photolysis
Calcium
Membranes
12 Citations (Scopus)

Modulation of neuronal voltage-activated calcium and sodium channels by polyamines and Ph

Chen, W., Harnett, M. T. & Smith, S., Jul 2007, In : Channels. 1, 4, p. 281-290 10 p.

Research output: Contribution to journalArticle

Sodium Channels
Polyamines
Calcium Channels
Modulation
Electric potential
32 Citations (Scopus)

N-Acetylcysteine for patients with prolonged hypotension as prophylaxis for acute renal failure (NEPHRON)

Komisarof, J. A., Gilkey, G. M., Peters, D., Koudelka, C. W., Meyer, M. M. & Smith, S., Feb 2007, In : Critical Care Medicine. 35, 2, p. 435-441 7 p.

Research output: Contribution to journalArticle

Acetylcysteine
Acute Kidney Injury
Hypotension
Organ Dysfunction Scores
Placebos
7 Citations (Scopus)

Neuronal voltage-activated calcium channels: On the roles of the α(1E) and β3 subunits

Smith, S., Piedras-Renterìa, E. S., Namkung, Y., Shin, H. S. & Tsien, R. W., 1999, In : Annals of the New York Academy of Sciences. 868, p. 175-198 24 p.

Research output: Contribution to journalArticle

Calcium Channels
Neurons
Antisense Oligonucleotides
Electric potential
Gene Targeting
14 Citations (Scopus)

Optical tracking of phenotypically diverse individual synapses on solitary tract nucleus neurons

Jin, Y. H., Cahill, E. A., Fernandes, L. G., Wang, X., Chen, W., Smith, S. & Andresen, M., Feb 2 2010, In : Brain Research. 1312, p. 54-66 13 p.

Research output: Contribution to journalArticle

Solitary Nucleus
Synapses
Neurons
Glutamic Acid
Visceral Afferents
2 Citations (Scopus)

Patient-specific insulin-resistanceguided infusion improves glycemic control in cardiac surgery

Caddell, K. A., Komanapalli, C. B., Slater, M., Hagg, D., Tibayan, F. F., Smith, S., Ahmann, A., Guyton, S. W. & Song, H., Dec 2010, In : Annals of Thoracic Surgery. 90, 6, p. 1818-1823 6 p.

Research output: Contribution to journalArticle

Thoracic Surgery
Insulin
Glycemic Index
Blood Glucose
Hypoglycemia
10 Citations (Scopus)

Polyamine distribution in the rat intestinal mucosa

Hosomi, M., Smith, S., Murphy, G. M. & Dowling, R. H., 1986, In : Journal of Chromatography B: Biomedical Sciences and Applications. 375, C, p. 267-275 9 p.

Research output: Contribution to journalArticle

Spermidine
Polyamines
Intestinal Mucosa
Rats
Putrescine
10 Citations (Scopus)

Predicted body weight-indexed extravascular lung water is elevated in acute respiratory distress syndrome

Phillips, C. R. & Smith, S., Jan 2009, In : Critical Care Medicine. 37, 1, p. 377-378 2 p.

Research output: Contribution to journalArticle

Extravascular Lung Water
Adult Respiratory Distress Syndrome
Body Weight
28 Citations (Scopus)

Presynaptic external calcium signaling involves the calcium-sensing receptor in neocortical nerve terminals

Chen, W., Bergsman, J. B., Wang, X., Gilkey, G., Pierpoint, C. R., Daniel, E. A., Awumey, E. M., Dauban, P., Dodd, R. H., Ruat, M. & Smith, S., Jan 5 2010, In : PLoS One. 5, 1, e8563.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Calcium Signaling
Cations
nerve tissue
Calcium
116 Citations (Scopus)

Primary Afferent Activation of Thermosensitive TRPV1 Triggers Asynchronous Glutamate Release at Central Neurons

Peters, J. H., McDougall, S. J., Fawley, J. A., Smith, S. & Andresen, M., Mar 11 2010, In : Neuron. 65, 5, p. 657-669 13 p.

Research output: Contribution to journalArticle

Visceral Afferents
Glutamic Acid
Neurons
Neuronal Plasticity
Solitary Nucleus

Radioimmunoassay for unconjugated and conjugated ursodeoxycholic acid in normal sera

Myszor, M. F., Smith, S., Murphy, G. M. & Dowling, R. H., 1982, In : Clinical Science. 62, 2

Research output: Contribution to journalArticle

Ursodeoxycholic Acid
Radioimmunoassay
Serum
39 Citations (Scopus)

Recordings from Single Neocortical Nerve Terminals Reveal a Nonselective Cation Channel Activated by Decreases in Extracellular Calcium

Smith, S., Bergsman, J. B., Harata, N. C., Scheller, R. H. & Tsien, R. W., Jan 22 2004, In : Neuron. 41, 2, p. 243-256 14 p.

Research output: Contribution to journalArticle

Cations
Presynaptic Terminals
Calcium
Spermidine
Neocortex
32 Citations (Scopus)

Role of polyamines in intestinal adaptation in the rat

Hosomi, M., Stace, N. H., Lirussi, F., Smith, S., Murphy, G. M. & Dowling, R. H., 1987, In : European Journal of Clinical Investigation. 17, 5, p. 375-385 11 p.

Research output: Contribution to journalArticle

Polyamines
Spermidine
Spermine
Rats
Intestines
62 Citations (Scopus)

Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor

Vyleta, N. P. & Smith, S., Mar 23 2011, In : Journal of Neuroscience. 31, 12, p. 4593-4606 14 p.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Glutamic Acid
Calcium
Calcium Channels
Neurons

Strong G-Protein-Mediated Inhibition of Sodium Channels

Mattheisen, G. B., Tsintsadze, T. & Smith, S., May 29 2018, In : Cell Reports. 23, 9, p. 2770-2781 12 p.

Research output: Contribution to journalArticle

Voltage-Gated Sodium Channels
Sodium Channels
GTP-Binding Proteins
Calcium-Sensing Receptors
Neurons
99 Citations (Scopus)

Synaptic vesicle endocytosis: fast and slow modes of membrane retrieval

Smith, S., Renden, R. & Von Gersdorff, H., Nov 2008, In : Trends in Neurosciences. 31, 11, p. 559-568 10 p.

Research output: Contribution to journalArticle

Synaptic Vesicles
Endocytosis
Exocytosis
Membranes
Flicker Fusion
41 Citations (Scopus)

Synthesis and characterization of a series of diarylguanidines that are noncompetitive N-methyl-D-aspartate receptor antagonists with neuroprotective properties

Keana, J. F. W., McBurney, R. N., Scherz, M. W., Fischer, J. B., Hamilton, P. N., Smith, S., Server, A. C., Finkbeiner, S., Stevens, C. F., Jahr, C. & Weber, E., 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 14, p. 5631-5635 5 p.

Research output: Contribution to journalArticle

tenocyclidine
N-Methylaspartate
N-Methyl-D-Aspartate Receptors
Phencyclidine Receptors
Dizocilpine Maleate
72 Citations (Scopus)

Targeted disruption of the Ca2+ channel β3 subunit reduces N- and L- type Ca2+ channel activity and alters the voltage-dependent activation of P/Q-type Ca2+ channels in neurons

Namkung, Y., Smith, S., Lee, S. B., Skrypnyk, N. V., Kim, H. L., Chin, H., Scheller, R. H., Tsien, R. W. & Shin, H. S., Sep 29 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 20, p. 12010-12015 6 p.

Research output: Contribution to journalArticle

Neurons
Gene Targeting
Synaptic Transmission
Norepinephrine
6 Citations (Scopus)

Ultradian variation of blood glucose in intensive care unit patients receiving insulin infusions

Smith, S., Oveson, K. E., Strauss, W., Raven, K., Lefevre, M. C., Ahmann, A. & Hagg, D., Oct 2007, In : Diabetes Care. 30, 10, p. 2503-2505 3 p.

Research output: Contribution to journalArticle

Insulin Infusion Systems
Activity Cycles
Intensive Care Units
Blood Glucose
Prospective Studies
82 Citations (Scopus)

Vasopressin inhibits glutamate release via two distinct modes in the brainstem.

Bailey, T. W., Jin, Y. H., Doyle, M. W., Smith, S. & Andresen, M., Jun 7 2006, In : The Journal of neuroscience : the official journal of the Society for Neuroscience. 26, 23, p. 6131-6142 12 p.

Research output: Contribution to journalArticle

Arginine Vasopressin
Vasopressins
Brain Stem
Glutamic Acid
Neurons