Stephen Smith

Research output

Research output per year 1987 1989 2008 2010 2022

• 36 Article
• 6 Letter
• 2 Short survey
• 1 Review article

Research output per year

Research output per year

Search results

• 1-(2-pyrimidinyl)piperazine antagonizes GABA-activated currents in cultured spinal neurones of the rat

  Smith, S. M. & Hughes, D., Jul 31 1989, In: Brain research. 493, 2, p. 366-367 2 p.

  Research output: Contribution to journal › Article › peer-review

  • 1-(2-pyrimidinyl)piperazine 100%
  • Buspirone 72%
  • Flurazepam 40%
  • Aminobutyrates 38%
  • Neurons 32%

• 15^th Annual Spring Brain Conference, March 10-13, 2004, summary report

  Anstrom, K., Bergles, D., Bradley, K., Cao, Y., Cestnick, L., Lee, S., Piedras-Rentería, E., Savoie, K., Smith, S. M. & Woolsey, T. A., Jun 2004, In: Somatosensory and Motor Research. 21, 2, p. 137-143 7 p.

  Research output: Contribution to journal › Article › peer-review

• Ablation of P/Q-type Ca²⁺ channel currents, altered synaptic transmission, and progressive ataxia in mice lacking the α(1A)-subunit

  Jun, K., Piedras-Rentería, E. S., Smith, S. M., Wheeler, D. B., Lee, S. B., Lee, T. G., Chin, H., Adams, M. E., Scheller, R. H., Tsien, R. W. & Shin, H. S., Dec 21 1999, In: Proceedings of the National Academy of Sciences of the United States of America. 96, 26, p. 15245-15250 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Dystonia 100%
  • Ataxia 89%
  • Synaptic Transmission 79%
  • Purkinje Cells 48%
  • Migraine Disorders 42%
  389 Scopus citations

• Baclofen and gamma-hydroxybutyrate withdrawal

  LeTourneau, J. L., Hagg, D. S. & Smith, S. M., Jun 2008, In: Neurocritical Care. 8, 3, p. 430-433 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Sodium Oxybate 100%
  • Baclofen 83%
  • Delirium 30%
  • Tremor 28%
  • Benzodiazepines 27%
  42 Scopus citations

• Caesium ions: A glycine-activated channel agonist in rat spinal cord neurones grown in cell culture

  Smith, S. M. & McBurney, R. N., 1989, In: British Journal of Pharmacology. 96, 4, p. 940-948 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Cesium 100%
  • Glycine 67%
  • Ions 55%
  • Spinal Cord 54%
  • Cell Culture Techniques 50%
  4 Scopus citations

• Caesium ions activate chloride channels in rat cultured spinal cord neurones.

  Hughes, D., McBurney, R. N., Smith, S. M. & Zorec, R., Nov 1 1987, In: The Journal of Physiology. 392, 1, p. 231-251 21 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cesium 100%
  • Chloride Channels 83%
  • Spinal Cord 54%
  • Ions 41%
  • Neurons 40%
  16 Scopus citations

• Calcium regulation of spontaneous and asynchronous neurotransmitter release

  Smith, S. M., Chen, W., Vyleta, N. P., Williams, C., Lee, C. H., Phillips, C. & Andresen, M. C., Sep 2012, In: Cell Calcium. 52, 3-4, p. 226-233 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Synapses 100%
  • Neurotransmitter Agents 95%
  • Calcium 74%
  • Calcium-Sensing Receptors 48%
  • Transient Receptor Potential Channels 47%
  32 Scopus citations

• Calcium-sensing receptor: A high-affinity presynaptic target for aminoglycoside-induced weakness

  Harnett, M. T., Chen, W. & Smith, S. M., Oct 2009, In: Neuropharmacology. 57, 5-6, p. 502-505 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Calcium-Sensing Receptors 100%
  • Aminoglycosides 83%
  • Calcium Channels 64%
  • Cations 30%
  • Inhibitory Concentration 50 27%
  10 Scopus citations

• Calcium-sensing receptor activation depresses synaptic transmission

  Phillips, C. G., Harnett, M. T., Chen, W. & Smith, S. M., Nov 12 2008, In: Journal of Neuroscience. 28, 46, p. 12062-12070 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Calcium-Sensing Receptors 100%
  • Synaptic Transmission 70%
  • Spermidine 24%
  • Carisoprodol 10%
  • Cations 9%
  48 Scopus citations

• Cerebral blood flow is proportional to cardiac index in patients with septic shock

  Smith, S. M., Padayachee, S., Modaresi, K. B., Smithies, M. N. & Bihari, D. J., Sep 1998, In: Journal of Critical Care. 13, 3, p. 104-109 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Septic Shock 100%
  • Cerebrovascular Circulation 93%
  • Extremities 17%
  • Regional Blood Flow 13%
  • Doppler Ultrasonography 12%
  41 Scopus citations

• Coactivation of multiple tightly coupled calcium channels triggers spontaneous release of GABA

  Williams, C., Chen, W., Lee, C. H., Yaeger, D., Vyleta, N. P. & Smith, S. M., Sep 2012, In: Nature Neuroscience. 15, 9, p. 1195-1197 3 p.

  Research output: Contribution to journal › Article › peer-review

  • Calcium Channels 100%
  • Synapses 85%
  • Action Potentials 84%
  • Neurotransmitter Agents 81%
  40 Scopus citations

• Conductance states activated by glycine and GABA in rat cultured spinal neurones

  Smith, S. M., Zorec, R. & McBurney, R. N., Apr 1 1989, In: The Journal of Membrane Biology. 108, 1, p. 45-52 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Glycine 100%
  • Neurons 60%
  • Chlorides 14%
  • Spinal Cord 11%
  • Cell Culture Techniques 10%
  33 Scopus citations

• Construction and validation of an ultraviolet germicidal irradiation system using locally available components

  Schnell, E., Karamooz, E., Harriff, M. J., Yates, J. E., Pfeiffer, C. D. & Smith, S. M., Jul 2021, In: PloS one. 16, July, e0255123.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mechanical Ventilators 100%
  • Health Personnel 49%
  • Coronavirus 47%
  • Decontamination 47%
  • Equipment and Supplies 34%
  3 Scopus citations

• Crystal violet reactions of coagulase negative staphylococci

  Freeman, R., Burdess, D. & Smith, S., 1994, In: Journal of Clinical Pathology. 47, 3, p. 283-285 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gentian Violet 100%
  • Coagulase 85%
  • Staphylococcus 75%
  • Staphylococcus saprophyticus 19%
  • Bacteriophages 12%
  4 Scopus citations

• Distinct actions of voltage-activated Ca²⁺ channel block on spontaneous release at excitatory and inhibitory central synapses

  Tsintsadze, T., Williams, C. L., Weingarten, D. J., von Gersdorff, H. & Smith, S. M., Apr 19 2017, In: Journal of Neuroscience. 37, 16, p. 4301-4310 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Synapses 100%
  • Calcium Channels 73%
  • Calcium Channel Blockers 44%
  • Synaptic Transmission 25%
  • Brain Stem 24%
  16 Scopus citations

• Enhanced excitability of cortical neurons in low-divalent solutions is primarily mediated by altered voltage-dependence of voltage-gated sodium channels

  Martiszus, B. J., Tsintsadze, T., Chang, W. & Smith, S. M., May 2021, In: eLife. 10, e67914.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Voltage-Gated Sodium Channels 100%
  • Cortical Excitability 99%
  • Calcium-Sensing Receptors 73%
  • Neurons 45%
  • Membrane Potentials 35%
  5 Scopus citations

• Extravascular lung water in sepsis-associated acute respiratory distress syndrome: Indexing with predicted body weight improves correlation with severity of illness and survival

  Phillips, C. R., Chesnutt, M. S. & Smith, S. M., Jan 2008, In: Critical care medicine. 36, 1, p. 69-73 5 p.

  Research output: Contribution to journal › Article › peer-review

  • Extravascular Lung Water 100%
  • Adult Respiratory Distress Syndrome 74%
  • Sepsis 54%
  • Body Weight 48%
  • Lung Injury 44%
  159 Scopus citations

• Fast inhibition of glutamate-activated currents by caffeine

  Vyleta, N. P. & Smith, S. M., Sep 10 2008, In: PloS one. 3, 9, e3155.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Caffeine 100%
  • caffeine 99%
  • glutamates 85%
  • Glutamic Acid 79%
  • Excitatory Postsynaptic Potentials 39%
  14 Scopus citations

• Large, Stable Spikes Exhibit Differential Broadening in Excitatory and Inhibitory Neocortical Boutons

  Ritzau-Jost, A., Tsintsadze, T., Krueger, M., Ader, J., Bechmann, I., Eilers, J., Barbour, B., Smith, S. M. & Hallermann, S., Jan 12 2021, In: Cell Reports. 34, 2, 108612.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Plastic Property 100%
  • Neocortex 96%
  • Neurotransmitter 95%
  • Interneurons 91%
  • Communication 78%
  12 Scopus citations

• Membrane capacitance changes induced by thrombin and calcium in single endothelial cells cultured from human umbilical vein

  Carter, T. D., Zupancic, G., Smith, S. M., Wheeler-Jones, C. & Ogden, D., Dec 15 1998, In: Journal of Physiology. 513, 3, p. 845-855 11 p.

  Research output: Contribution to journal › Article › peer-review

  • DM-nitrophen 100%
  • Human Umbilical Vein Endothelial Cells 72%
  • Photolysis 71%
  • Thrombin 66%
  • Calcium 46%
  10 Scopus citations

• Modulation of neuronal voltage-activated calcium and sodium channels by polyamines and Ph

  Chen, W., Harnett, M. T. & Smith, S. M., 2007, In: Channels. 1, 4, p. 281-290 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Polyamines 100%
  • Sodium Channels 99%
  • Calcium Channels 90%
  • Polyamine 90%
  • Spermidine 44%
  13 Scopus citations

• N-Acetylcysteine for patients with prolonged hypotension as prophylaxis for acute renal failure (NEPHRON)

  Komisarof, J. A., Gilkey, G. M., Peters, D. M., Koudelka, C. W., Meyer, M. M. & Smith, S. M., Feb 2007, In: Critical care medicine. 35, 2, p. 435-441 7 p.

  Research output: Contribution to journal › Article › peer-review

  • Acetylcysteine 100%
  • Acute Kidney Injury 84%
  • Hypotension 82%
  • Organ Dysfunction Scores 39%
  • Placebos 27%
  37 Scopus citations

• Neuronal voltage-activated calcium channels: On the roles of the α(1E) and β₃ subunits

  Smith, S. M., Piedras-Renterìa, E. S., Namkung, Y., Shin, H. S. & Tsien, R. W., Jan 1 1999, In: Annals of the New York Academy of Sciences. 868, p. 175-198 24 p.

  Research output: Contribution to journal › Article › peer-review

  • Calcium 100%
  • Antisense Oligonucleotide 93%
  • Calcium Channels 72%
  • Neuron 66%
  • Current Density 48%
  7 Scopus citations

• Optical tracking of phenotypically diverse individual synapses on solitary tract nucleus neurons

  Jin, Y. H., Cahill, E. A., Fernandes, L. G., Wang, X., Chen, W., Smith, S. M. & Andresen, M. C., Feb 2 2010, In: Brain research. 1312, p. 54-66 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Solitary Nucleus 100%
  • Synapses 74%
  • FM1 43 56%
  • Neurons 50%
  • Glutamic Acid 20%
  14 Scopus citations

• Patient-specific insulin-resistanceguided infusion improves glycemic control in cardiac surgery

  Caddell, K. A., Komanapalli, C. B., Slater, M. S., Hagg, D., Tibayan, F. A., Smith, S., Ahmann, A., Guyton, S. W. & Song, H. K., Dec 2010, In: Annals of Thoracic Surgery. 90, 6, p. 1818-1823 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Thoracic Surgery 100%
  • Insulin 75%
  • Glycemic Index 37%
  • Blood Glucose 34%
  • Hypoglycemia 26%
  3 Scopus citations

• Presynaptic external calcium signaling involves the calcium-sensing receptor in neocortical nerve terminals

  Chen, W., Bergsman, J. B., Wang, X., Gilkey, G., Pierpoint, C. R., Daniel, E. A., Awumey, E. M., Dauban, P., Dodd, R. H., Ruat, M. & Smith, S. M., Jan 5 2010, In: PloS one. 5, 1, e8563.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Calcium-Sensing Receptors 100%
  • Calcium Signaling 89%
  • Cations 76%
  • Calcium 34%
  • (R)-2-(1-(1-naphthyl)ethyl-aminom-ethyl)indole 26%
  34 Scopus citations

• Primary Afferent Activation of Thermosensitive TRPV1 Triggers Asynchronous Glutamate Release at Central Neurons

  Peters, J. H., McDougall, S. J., Fawley, J. A., Smith, S. M. & Andresen, M. C., Mar 11 2010, In: Neuron. 65, 5, p. 657-669 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Visceral Afferents 100%
  • Glutamic Acid 57%
  • TRPV1 receptor 43%
  • Neurons 40%
  • Solitary Nucleus 40%
  144 Scopus citations

• Recordings from Single Neocortical Nerve Terminals Reveal a Nonselective Cation Channel Activated by Decreases in Extracellular Calcium

  Smith, S. M., Bergsman, J. B., Harata, N. C., Scheller, R. H. & Tsien, R. W., Jan 22 2004, In: Neuron. 41, 2, p. 243-256 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cations 100%
  • Presynaptic Terminals 73%
  • Calcium 67%
  • Spermidine 43%
  • Neocortex 37%
  46 Scopus citations

• Reduced affinity of calcium sensing-receptor heterodimers and reduced mutant homodimer trafficking combine to impair function in a model of familial hypocalciuric hypercalcemia type 1

  Wang, X., Lundblad, J. & Smith, S. M., Jul 2022, In: PloS one. 17, 7 July, e0266993.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hypocalciuric hypercalcemia, familial, type 1 100%
  • Calcium-Sensing Receptors 79%
  • Mutant Proteins 28%
  • Mutation 14%
  • Cell Membrane 9%

• Spontaneous glutamate release is independent of calcium influx and tonically activated by the calcium-sensing receptor

  Vyleta, N. P. & Smith, S. M., Mar 23 2011, In: Journal of Neuroscience. 31, 12, p. 4593-4606 14 p.

  Research output: Contribution to journal › Article › peer-review

  • Calcium-Sensing Receptors 100%
  • Glutamic Acid 66%
  • Calcium 51%
  • Calcium Channels 32%
  • Neurons 27%
  74 Scopus citations

• Strong G-Protein-Mediated Inhibition of Sodium Channels

  Mattheisen, G. B., Tsintsadze, T. & Smith, S. M., May 29 2018, In: Cell Reports. 23, 9, p. 2770-2781 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Voltage-Gated Sodium Channels 100%
  • Sodium Channels 86%
  • GTP-Binding Proteins 73%
  • Cinacalcet 46%
  • Calcium-Sensing Receptors 29%
  1 Scopus citations

• Synaptic vesicle endocytosis: fast and slow modes of membrane retrieval

  Smith, S. M., Renden, R. & von Gersdorff, H., Nov 2008, In: Trends in Neurosciences. 31, 11, p. 559-568 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Synaptic Vesicles 100%
  • Endocytosis 86%
  • Exocytosis 71%
  • Membranes 51%
  • Flicker Fusion 33%
  106 Scopus citations

• Synthesis and characterization of a series of diarylguanidines that are noncompetitive N-methyl-D-aspartate receptor antagonists with neuroprotective properties

  Keana, J. F. W., McBurney, R. N., Scherz, M. W., Fischer, J. B., Hamilton, P. N., Smith, S. M., Server, A. C., Finkbeiner, S., Stevens, C. F., Jahr, C. & Weber, E., 1989, In: Proceedings of the National Academy of Sciences of the United States of America. 86, 14, p. 5631-5635 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • N-Methylaspartate 100%
  • N-Methyl-D-Aspartate Receptors 92%
  • tenocyclidine 89%
  • Phencyclidine Receptors 79%
  • Dizocilpine Maleate 55%
  44 Scopus citations

• Targeted disruption of the Ca²⁺ channel β₃ subunit reduces N- and L-type Ca²⁺ channel activity and alters the voltage-dependent activation of P/Q-type Ca²⁺ channels in neurons

  Namkung, Y., Smith, S. M., Lee, S. B., Skrypnyk, N. V., Kim, H. L., Chin, H., Scheller, R. H., Tsien, R. W. & Shin, H. S., Sep 29 1998, In: Proceedings of the National Academy of Sciences of the United States of America. 95, 20, p. 12010-12015 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Neurons 100%
  • Gene Targeting 63%
  • Animals 54%
  • Synaptic Transmission 50%
  • Norepinephrine 45%
  76 Scopus citations

• Ultradian variation of blood glucose in intensive care unit patients receiving insulin infusions

  Smith, S. M., Oveson, K. E., Strauss, W., Raven, K., Lefevre, M. C., Ahmann, A. J. & Hagg, D. S., Oct 2007, In: Diabetes care. 30, 10, p. 2503-2505 3 p.

  Research output: Contribution to journal › Article › peer-review
  8 Scopus citations

• Vasopressin inhibits glutamate release via two distinct modes in the brainstem.

  Bailey, T. W., Jin, Y. H., Doyle, M. W., Smith, S. M. & Andresen, M. C., Jun 7 2006, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 26, 23, p. 6131-6142 12 p.

  Research output: Contribution to journal › Article › peer-review

  • Arginine Vasopressin 100%
  • Vasopressins 87%
  • Brain Stem 75%
  • Glutamic Acid 73%
  • Neurons 37%
  92 Scopus citations