Stephen Back

Professor

  • 7779 Citations
  • 46 h-Index
1983 …2020

Research output per year

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Research Output

  • 7779 Citations
  • 46 h-Index
  • 86 Article
  • 8 Chapter
  • 1 Letter
  • 1 Review article
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Article
1983

Characterization of α2-macroglobulin from plasma of cystic fibrosis patients and controls

Back, S. & Alhadef, J. A., 1983, In : Biochemical Medicine. 30, 1, p. 34-42 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
6 Scopus citations
1985

Altered isoelectric focusing of α2-macroglobulin from plasma of patients with diabetes mellitus

Back, S., Lorenzi, M. & Alhadeff, J. A., Jul 30 1985, In : Clinica Chimica Acta. 150, 1, p. 21-29 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
1989

Fluorescent histochemical localization of neutral endopeptidase-24.11 (enkephalinase) in the rat spinal cord

Back, S. & Gorenstein, C., 1989, In : Journal of Comparative Neurology. 280, 3, p. 436-450 15 p.

Research output: Contribution to journalArticle

14 Scopus citations
32 Scopus citations
1990

A case of group B streptococcal pyomyositis

Back, S., O'Neill, T., Fishbein, G. & Gwinup, G., 1990, In : Reviews of Infectious Diseases. 12, 5, p. 784-787 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Fluorescent histochemical localization of neutral endopeptidase-24.11 (enkephalinase) in the rat brainstem

Back, S. & Gorenstein, C., 1990, In : Journal of Comparative Neurology. 296, 1, p. 130-158 29 p.

Research output: Contribution to journalArticle

13 Scopus citations
1992
18 Scopus citations

Differential isoform profiles of α2-macroglobulin from plasma of patients with chronic-progressive or relapsing-remitting multiple sclerosis

Back, S. & Alhadeff, J. A., Oct 15 1992, In : Clinica Chimica Acta. 211, 1-2, p. 27-36 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
1993

Ventral mesencephalic and cortical transplants into the rat striatum display enhanced activity for neutral endopeptidase 24.11 ('enkephalinase'; CALLA)

Back, S., Colon, M., Fallon, J. H., Meyskens, F. L. & Loughlin, S. E., May 28 1993, In : Brain Research. 612, 1-2, p. 85-95 11 p.

Research output: Contribution to journalArticle

3 Scopus citations
1994
7 Scopus citations
1996

Cystine deprivation induces oligodendroglial death: Rescue by free radical scavengers and by a diffusible glial factor

Yonezawa, M., Back, S., Gan, X., Rosenberg, P. A. & Volpe, J. J., Aug 1996, In : Journal of Neurochemistry. 67, 2, p. 566-573 8 p.

Research output: Contribution to journalArticle

99 Scopus citations
1997

Cellular and molecular pathogenesis of periventricular white matter injury

Back, S. & Volpe, J. J., 1997, In : Mental Retardation and Developmental Disabilities Research Reviews. 3, 1, p. 96-107 12 p.

Research output: Contribution to journalArticle

87 Scopus citations
1998

Human oligodendroglial development: Relationship to periventricular leukomalacia

Kinney, H. C. & Back, S., 1998, In : Seminars in Pediatric Neurology. 5, 3, p. 180-189 10 p.

Research output: Contribution to journalArticle

142 Scopus citations

Maturation-dependent vulnerability of oligodendrocytes to oxidative stress-induced death caused by glutathione depletion

Back, S., Gan, X., Li, Y., Rosenberg, P. A. & Volpe, J. J., Aug 15 1998, In : Journal of Neuroscience. 18, 16, p. 6241-6253 13 p.

Research output: Contribution to journalArticle

425 Scopus citations
1999

A new Alamar Blue viability assay to rapidly quantify oligodendrocyte death

Back, S., Khan, R., Gan, X., Rosenberg, P. A. & Volpe, J. J., Sep 15 1999, In : Journal of Neuroscience Methods. 91, 1-2, p. 47-54 8 p.

Research output: Contribution to journalArticle

71 Scopus citations

Intracellular redox state determines whether nitric oxide is toxic or protective to rat oligodendrocytes in culture

Rosenberg, P. A., Li, Y., Ali, S., Altiok, N., Back, S. & Volpe, J. J., 1999, In : Journal of Neurochemistry. 73, 2, p. 476-484 9 p.

Research output: Contribution to journalArticle

76 Scopus citations
2000

BDNF blocks caspase-3 activation in neonatal hypoxia-ischemia

Hee Han, B., D'Costa, A., Back, S., Parsadanian, M., Patel, S., Shah, A. R., Gidday, J. M., Srinivasan, A., Deshmukh, M. & Holtzman, D. M., Feb 2000, In : Neurobiology of Disease. 7, 1, p. 38-53 16 p.

Research output: Contribution to journalArticle

237 Scopus citations
2001

Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury

Back, S., Luo, N. L., Borenstein, N. S., Levine, J. M., Volpe, J. J. & Kinney, H. C., Feb 15 2001, In : Journal of Neuroscience. 21, 4, p. 1302-1312 11 p.

Research output: Contribution to journalArticle

692 Scopus citations

Recent advances in human perinatal white matter injury

Back, S., 2001, In : Progress in Brain Research. 132, p. 131-147 17 p.

Research output: Contribution to journalArticle

34 Scopus citations

Volumetric brain differences in children with periventricular T2-signal hyperintensities: A grouping by gestational age at birth

Panigrahy, A., Barnes, P. D., Robertson, R. L., Back, S., Sleeper, L. A., Sayre, J. W., Kinney, H. C. & Volpe, J. J., 2001, In : American Journal of Roentgenology. 177, 3, p. 695-702 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
2002
128 Scopus citations

Selective vulnerability of late oligodendrocyte progenitors to hypoxia-ischemia

Back, S., Han, B. H., Luo, N. L., Chricton, C. A., Xanthoudakis, S., Tam, J., Arvin, K. L. & Holtzman, D. M., Jan 15 2002, In : Journal of Neuroscience. 22, 2, p. 455-463 9 p.

Research output: Contribution to journalArticle

579 Scopus citations
2003

Mature myelin basic protein-expressing oligodendrocytes are insensitive to kainate toxicity

Rosenberg, P. A., Dai, W., Gan, X. D., Ali, S., Fu, J., Back, S., Sanchez, R. M., Segal, M. M., Follett, P. L., Jensen, F. E. & Volpe, J. J., Jan 15 2003, In : Journal of Neuroscience Research. 71, 2, p. 237-245 9 p.

Research output: Contribution to journalArticle

112 Scopus citations

Quantitative analysis of perinatal rodent oligodendrocyte lineage progression and its correlation with human

Craig, A., Luo, N. L., Beardsley, D. J., Wingate-Pearse, N., Walker, D. W., Hohimer, A. R. & Back, S., Jun 1 2003, In : Experimental Neurology. 181, 2, p. 231-240 10 p.

Research output: Contribution to journalArticle

194 Scopus citations
2004

CD44 expression identifies astrocyte-restricted precursor cells

Liu, Y., Han, S. S. W., Wu, Y., Tuohy, T. M. F., Xue, H., Cai, J., Back, S., Sherman, L. L., Fischer, I. & Rao, M. S., Dec 1 2004, In : Developmental Biology. 276, 1, p. 31-46 16 p.

Research output: Contribution to journalArticle

130 Scopus citations

Emerging concepts in periventricular white matter injury

Back, S. & Rivkees, S. A., Dec 2004, In : Seminars in Perinatology. 28, 6, p. 405-414 10 p.

Research output: Contribution to journalArticle

161 Scopus citations

Preterm Fetal Hypoxia-Ischemia Causes Hypertonia and Motor Deficits in the Neonatal Rabbit: A Model for Human Cerebral Palsy?

Derrick, M., Luo, N. L., Bregman, J. C., Jilling, T., Ji, X., Fisher, K., Gladson, C. L., Beardsley, D. J., Murdoch, G., Back, S. & Tan, S., Jan 7 2004, In : Journal of Neuroscience. 24, 1, p. 24-34 11 p.

Research output: Contribution to journalArticle

141 Scopus citations
2005

Developmental changes in diffusion anisotropy coincide with immature oligodendrocyte progression and maturation of compound action potential

Drobyshevsky, A., Song, S. K., Gamkrelidze, G., Wyrwicz, A. M., Derrick, M., Meng, F., Li, L., Ji, X., Trommer, B., Beardsley, D. J., Luo, N. L., Back, S. & Tan, S., Jul 22 2005, In : Journal of Neuroscience. 25, 25, p. 5988-5997 10 p.

Research output: Contribution to journalArticle

146 Scopus citations

Hyaluronan accumulates in demyelinated lesions and inhibits oligodendrocyte progenitor maturation

Back, S., Tuohy, T. M. F., Chen, H., Wallingford, N., Craig, A., Struve, J., Ning, L. L., Banine, F., Liu, Y., Chang, A., Trapp, B. D., Bebo, B. F., Rao, M. S. & Sherman, L. L., Sep 2005, In : Nature Medicine. 11, 9, p. 966-972 7 p.

Research output: Contribution to journalArticle

375 Scopus citations

Molecular networks perturbed in a developmental animal model of brain injury

Kisby, G. E., Standley, M., Lu, X., O'Malley, J., Lin, B., Muniz, J., Luo, N. L., Pattee, P., Back, S. & Nagalla, S. R., Jun 2005, In : Neurobiology of Disease. 19, 1-2, p. 108-118 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Selective vulnerability of preterm white matter to oxidative damage defined by F2-isoprostanes

Back, S., Luo, N. L., Mallinson, R. A., O'Malley, J. P., Wallen, L. D., Frei, B., Morrow, J. D., Petito, C. K., Roberts, C., Murdoch, G. H. & Montine, T. J., Jul 2005, In : Annals of Neurology. 58, 1, p. 108-120 13 p.

Research output: Contribution to journalArticle

176 Scopus citations
2006
258 Scopus citations

Protective effects of caffeine on chronic hypoxia-induced perinatal white matter injury

Back, S., Craig, A., Luo, N. L., Ren, J., Akundi, R. S., Ribeiro, I. & Rivkees, S. A., Dec 2006, In : Annals of Neurology. 60, 6, p. 696-705 10 p.

Research output: Contribution to journalArticle

123 Scopus citations

Role of instrumented fetal sheep preparations in defining the pathogenesis of human periventricular white-matter injury

Back, S., Riddle, A. & Hohimer, A. R., Jul 2006, In : Journal of Child Neurology. 21, 7, p. 582-589 8 p.

Research output: Contribution to journalArticle

87 Scopus citations

Spatial heterogeneity in oligodendrocyte lineage maturation and not cerebral blood flow predicts fetal ovine periventricular white matter injury

Riddle, A., Ning, L. L., Manese, M., Beardsley, D. J., Green, L., Rorvik, D. A., Kelly, K. A., Barlow, C. H., Kelly, J. J., Hohimer, A. R. & Back, S., Mar 15 2006, In : Journal of Neuroscience. 26, 11, p. 3045-3055 11 p.

Research output: Contribution to journalArticle

146 Scopus citations
2007

Hypoxia-ischemia preferentially triggers glutamate depletion from oligodendroglia and axons in perinatal cerebral white matter

Back, S., Craig, A., Kayton, R. J., Luo, N. L., Meshul, C. K., Allcock, N. & Fern, R., Feb 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, 2, p. 334-347 14 p.

Research output: Contribution to journalArticle

83 Scopus citations

Large-scale generation of highly enriched neural stem-cell-derived oligodendroglial cultures: Maturation-dependent differences in insulin-like growth factor-mediated signal transduction

Broughton, S. K., Chen, H., Riddle, A., Kuhn, S. E., Nagalla, S., Roberts, C. & Back, S., Feb 2007, In : Journal of Neurochemistry. 100, 3, p. 628-638 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Maturation-dependent vulnerability of perinatal white matter in premature birth

Back, S., Riddle, A. & McClure, M. M., Feb 2007, In : Stroke. 38, 2 PART 2, p. 724-730 7 p.

Research output: Contribution to journalArticle

261 Scopus citations
2008

A 'GAG' reflex prevents repair of the damaged CNS

Sherman, L. L. & Back, S., Jan 2008, In : Trends in Neurosciences. 31, 1, p. 44-52 9 p.

Research output: Contribution to journalArticle

78 Scopus citations

Arrested oligodendrocyte lineage maturation in chronic perinatal white matter injury

Segovia, K. N., McClure, M., Moravec, M., Ning, L. L., Wan, Y., Gong, X., Riddle, A., Craig, A., Struve, J., Sherman, L. L. & Back, S., Apr 2008, In : Annals of Neurology. 63, 4, p. 520-530 11 p.

Research output: Contribution to journalArticle

214 Scopus citations

Cerebral blood flow heterogeneity in preterm sheep: Lack of physiologic support for vascular boundary zones in fetal cerebral white matter

McClure, M. M., Riddle, A., Manese, M., Luo, N. L., Rorvik, D. A., Kelly, K. A., Barlow, C. H., Kelly, J. J., Vinecore, K., Roberts, C., Hohimer, A. R. & Back, S., May 2008, In : Journal of Cerebral Blood Flow and Metabolism. 28, 5, p. 995-1008 14 p.

Research output: Contribution to journalArticle

50 Scopus citations
2010

Timing of appearance of late oligodendrocyte progenitors coincides with enhanced susceptibility of preterm rabbit cerebral white matter to hypoxia-ischemia

Buser, J. R., Segovia, K. N., Dean, J. M., Nelson, K., Beardsley, D., Gong, X., Luo, N. L., Ren, J., Wan, Y., Riddle, A., McClure, M. M., Ji, X., Derrick, M., Hohimer, A. R., Back, S. & Tan, S., May 2010, In : Journal of Cerebral Blood Flow and Metabolism. 30, 5, p. 1053-1065 13 p.

Research output: Contribution to journalArticle

55 Scopus citations

Towards improved animal models of neonatal white matter injury associated with cerebral palsy

Silbereis, J. C., Huang, E. J., Back, S. & Rowitch, D. H., Nov 2010, In : DMM Disease Models and Mechanisms. 3, 11-12, p. 678-688 11 p.

Research output: Contribution to journalArticle

65 Scopus citations
2011

An organotypic slice culture model of chronic white matter injury with maturation arrest of oligodendrocyte progenitors

Dean, J. M., Riddle, A., Maire, J., Hansen, K. D., Preston, M., Barnes, A., Sherman, L. L. & Back, S., 2011, In : Molecular Neurodegeneration. 6, 1, 46.

Research output: Contribution to journalArticle

21 Scopus citations

Diffusion characteristics associated with neuronal injury and glial activation following hypoxia-ischemia in the immature brain

Lodygensky, G. A., West, T., Moravec, M. D., Back, S., Dikranian, K., Holtzman, D. M. & Neil, J. J., Sep 2011, In : Magnetic Resonance in Medicine. 66, 3, p. 839-845 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Histopathological correlates of magnetic resonance imaging-defined chronic perinatal white matter injury

Riddle, A., Dean, J., Buser, J. R., Gong, X., Maire, J., Chen, K., Ahmad, T., Cai, V., Nguyen, T., Kroenke, C. C., Hohimer, A. R. & Back, S., Sep 2011, In : Annals of Neurology. 70, 3, p. 493-507 15 p.

Research output: Contribution to journalArticle

94 Scopus citations

Strain-specific differences in perinatal rodent oligodendrocyte lineage progression and its correlation with human

Dean, J. M., Moravec, M. D., Grafe, M., Abend, N., Ren, J., Gong, X., Volpe, J. J., Jensen, F. E., Hohimer, A. R. & Back, S., Oct 2011, In : Developmental Neuroscience. 33, 3-4, p. 251-260 10 p.

Research output: Contribution to journalArticle

51 Scopus citations

White matter lesions defined by diffusion tensor imaging in older adults

Back, S., Kroenke, C. C., Sherman, L. L., Lawrence, G., Gong, X., Taber, E. N., Sonnen, J. A., Larson, E. B. & Montine, T. J., Sep 2011, In : Annals of Neurology. 70, 3, p. 465-476 12 p.

Research output: Contribution to journalArticle

74 Scopus citations