Soren Impey

Associate Professor

  • 11547 Citations
  • 50 h-Index
19942019

Research output per year

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Research Output

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Article
2019
Open Access
2 Scopus citations

USP8 Deubiquitinates the Leptin Receptor and Is Necessary for Leptin-Mediated Synapse Formation

Bland, T., Sahin, G. S., Zhu, M., Dillon, C., Impey, S., Appleyard, S. M. & Wayman, G. A., Jul 4 2019, In : Endocrinology. 160, 8, p. 1982-1998 17 p., 201900107.

Research output: Contribution to journalArticle

5 Scopus citations
2018

Post-translational modification localizes MYC to the nuclear pore basket to regulate a subset of target genes involved in cellular responses to environmental signals

Su, Y., Pelz, C., Huang, T., Torkenczy, K., Wang, X., Cherry, A., Daniel, C. J., Liang, J., Nan, X., Dai, M. S., Adey, A., Impey, S. & Sears, R. C., Nov 1 2018, In : Genes and Development. 32, 21-22, p. 1398-1419 22 p.

Research output: Contribution to journalArticle

20 Scopus citations
2017

Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome

Johnson, L. A., Torres, E. R. S., Impey, S., Stevens, J. F. & Raber, J., Mar 8 2017, In : Scientific Reports. 7, 43701.

Research output: Contribution to journalArticle

29 Scopus citations

Bi-directional and shared epigenomic signatures following proton and 56Fe irradiation

Impey, S., Jopson, T., Pelz, C., Tafessu, A., Fareh, F., Zuloaga, D., Marzulla, T., Riparip, L. K., Stewart, B., Rosi, S., Turker, M. S. & Raber, J., Dec 1 2017, In : Scientific Reports. 7, 1, 10227.

Research output: Contribution to journalArticle

17 Scopus citations

Time-lapse imaging of microRNA activity reveals the kinetics of microRNA activation in single living cells

Ando, H., Hirose, M., Kurosawa, G., Impey, S. & Mikoshiba, K., Dec 1 2017, In : Scientific Reports. 7, 1, 12642.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Proton irradiation induces persistent and tissue-specific DNA methylation changes in the left ventricle and hippocampus

Impey, S., Pelz, C., Tafessu, A., Marzulla, T., Turker, M. S. & Raber, J., 2016, In : BMC Genomics. 17, 1, 273.

Research output: Contribution to journalArticle

23 Scopus citations

Short- and long-term effects of 56Fe irradiation on cognition and hippocampal DNA methylation and gene expression

Impey, S., Jopson, T., Pelz, C., Tafessu, A., Fareh, F., Zuloaga, D., Marzulla, T., Riparip, L. K., Stewart, B., Rosi, S., Turker, M. S. & Raber, J., Oct 24 2016, In : BMC Genomics. 17, 1, 825.

Research output: Contribution to journalArticle

23 Scopus citations

Status epilepticus stimulates NDEL1 expression via the CREB/CRE pathway in the adult mouse brain

Choi, Y. S., Lee, B., Hansen, K. F., Aten, S., Horning, P., Wheaton, K. L., Impey, S., Hoyt, K. R. & Obrietan, K., Sep 7 2016, In : Neuroscience. 331, p. 1-12 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

Targeted deletion of miR-132/-212 impairs memory and alters the hippocampal transcriptome

Hansen, K. F., Sakamoto, K., Aten, S., Snider, K. H., Loeser, J., Hesse, A. M., Page, C. E., Pelz, C., Simon, J., Arthur, C., Impey, S. & Obrietan, K., Feb 2016, In : Learning and Memory. 23, 2, p. 61-71 11 p.

Research output: Contribution to journalArticle

36 Scopus citations
2015

Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling

Zhang, Q. S., Benedetti, E., Deater, M., Schubert, K., Major, A., Pelz, C., Impey, S., Marquez-Loza, L., Rathbun, R. K., Kato, S., Bagby, G. C. & Grompe, M., Jan 13 2015, In : Stem Cell Reports. 4, 1, p. 90-102 13 p.

Research output: Contribution to journalArticle

14 Scopus citations

RNA sequencing distinguishes benign from malignant pancreatic lesions sampled by EUS-guided FNA

Rodriguez, S. A., Impey, S., Pelz, C., Enestvedt, B., Bakis, G., Owens, M. & Morgan, T., Nov 11 2015, (Accepted/In press) In : Gastrointestinal Endoscopy.

Research output: Contribution to journalArticle

13 Scopus citations
2014

Foxa3 induces goblet cell metaplasia and inhibits innate antiviral immunity

Chen, G., Korfhagen, T. R., Karp, C. L., Impey, S., Xu, Y., Randell, S. H., Kitzmiller, J., Maeda, Y., Haitchi, H. M., Sridharan, A., Senft, A. P. & Whitsett, J. A., Feb 1 2014, In : American journal of respiratory and critical care medicine. 189, 3, p. 301-313 13 p.

Research output: Contribution to journalArticle

65 Scopus citations

Leptin induces hippocampal synaptogenesis via CREB-regulated MicroRNA-132 suppression of p250GAP

Dhar, M., Zhu, M., Impey, S., Lambert, T. J., Bland, T., Karatsoreos, I. N., Nakazawa, T., Appleyard, S. M. & Wayman, G. A., Jul 2014, In : Molecular Endocrinology. 28, 7, p. 1073-1087 15 p.

Research output: Contribution to journalArticle

50 Scopus citations

Profiling status epilepticus-induced changes in hippocampal RNA expression using high-throughput RNA sequencing

Hansen, K. F., Sakamoto, K., Pelz, C., Impey, S. & Obrietan, K., 2014, In : Scientific Reports. 4, 6930.

Research output: Contribution to journalArticle

42 Scopus citations

Targeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancer

Farrell, A. S., Allen-Petersen, B., Daniel, C. J., Wang, X., Wang, Z., Rodriguez, S., Impey, S., Oddo, J., Vitek, M. P., Lopez, C., Christensen, D. J., Sheppard, B. & Sears, R. C., Jun 2014, In : Molecular Cancer Research. 12, 6, p. 924-939 16 p.

Research output: Contribution to journalArticle

56 Scopus citations

The environmental neurotoxicant PCB 95 promotes synaptogenesis via ryanodine receptor-dependent miR132 upregulation

Lesiak, A., Zhu, M., Chen, H., Appleyard, S. M., Impey, S., Lein, P. J. & Wayman, G. A., 2014, In : Journal of Neuroscience. 34, 3, p. 717-725 9 p.

Research output: Contribution to journalArticle

48 Scopus citations
2013

A Genome-Wide Screen of CREB Occupancy Identifies the RhoA Inhibitors Par6C and Rnd3 as Regulators of BDNF-Induced Synaptogenesis

Lesiak, A., Pelz, C., Ando, H., Zhu, M., Davare, M., Lambert, T. J., Hansen, K. F., Obrietan, K., Appleyard, S. M., Impey, S. & Wayman, G. A., Jun 6 2013, In : PloS one. 8, 6, e64658.

Research output: Contribution to journalArticle

45 Scopus citations

MiRNA-132: A dynamic regulator of cognitive capacity

Hansen, K. F., Karelina, K., Sakamoto, K., Wayman, G. A., Impey, S. & Obrietan, K., May 2013, In : Brain Structure and Function. 218, 3, p. 817-831 15 p.

Research output: Contribution to journalArticle

87 Scopus citations

Pin1 Regulates the Dynamics of c-Myc DNA Binding To Facilitate Target Gene Regulation and Oncogenesis

Farrell, A. S., Pelz, C., Wang, X., Daniel, C. J., Wang, Z., Su, Y., Janghorban, M., Zhang, X., Morgan, C., Impey, S. & Sears, R. C., Aug 2013, In : Molecular and cellular biology. 33, 15, p. 2930-2949 20 p.

Research output: Contribution to journalArticle

62 Scopus citations
2012

Mitogen- and stress-activated kinases regulate progenitor cell proliferation and neuron development in the adult dentate gyrus

Choi, Y. S., Karelina, K., Alzate-Correa, D., Hoyt, K. R., Impey, S., Arthur, J. S. & Obrietan, K., Dec 2012, In : Journal of neurochemistry. 123, 5, p. 676-688 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

PCB-95 modulates the calcium-dependent signaling pathway responsible for activity-dependent dendritic growth

Wayman, G. A., Bose, D. D., Yang, D., Lesiak, A., Bruun, D., Impey, S., Ledoux, V., Pessah, I. N. & Lein, P. J., Jun 2012, In : Environmental health perspectives. 120, 7, p. 1003-1009 7 p.

Research output: Contribution to journalArticle

73 Scopus citations
2011

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

Palmieri, M., Impey, S., Kang, H., di Ronza, A., Pelz, C., Sardiello, M. & Ballabio, A., Oct 1 2011, In : Human molecular genetics. 20, 19, p. 3852-3866 15 p., ddr306.

Research output: Contribution to journalArticle

369 Scopus citations

Fusion between intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming

Powell, A. E., Anderson, E. C., Davies, P. S., Silk, A. D., Pelz, C., Impey, S. & Wong, M. H., Feb 15 2011, In : Cancer Research. 71, 4, p. 1497-1505 9 p.

Research output: Contribution to journalArticle

113 Scopus citations

KDM5B regulates embryonic stem cell self-renewal and represses cryptic intragenic transcription

Xie, L., Pelz, C., Wang, W., Bashar, A., Varlamova, O., Shadle, S. & Impey, S., Apr 20 2011, In : EMBO Journal. 30, 8, p. 1473-1484 12 p.

Research output: Contribution to journalArticle

92 Scopus citations
2010

An activity-induced microRNA controls dendritic spine formation by regulating Rac1-PAK signaling

Impey, S., Davare, M., Lasiek, A., Fortin, D., Ando, H., Varlamova, O., Obrietan, K., Soderling, T. R., Goodman, R. H. & Wayman, G. A., Jan 2010, In : Molecular and Cellular Neuroscience. 43, 1, p. 146-156 11 p.

Research output: Contribution to journalArticle

209 Scopus citations

MicroRNA regulation of neural stem cells and neurogenesis

Shi, Y., Zhao, X., Hsieh, J., Wichterle, H., Impey, S., Banerjee, S., Neveu, P. & Kosik, K. S., Nov 10 2010, In : Journal of Neuroscience. 30, 45, p. 14931-14936 6 p.

Research output: Contribution to journalArticle

155 Scopus citations

Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins

Remenyi, J., Hunter, C. J., Cole, C., Ando, H., Impey, S., Monk, C. E., Martin, K. J., Barton, G. J., Hutvagner, G. & Arthur, J. S. C., Jun 1 2010, In : Biochemical Journal. 428, 2, p. 281-291 11 p.

Research output: Contribution to journalArticle

155 Scopus citations

Transgenic miR132 alters neuronal spine density and impairs novel object recognition memory

Hansen, K. F., Sakamoto, K., Wayman, G. A., Impey, S. & Obrietan, K., 2010, In : PloS one. 5, 11, e15497.

Research output: Contribution to journalArticle

166 Scopus citations
2008

An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP

Wayman, G. A., Davare, M., Ando, H., Fortin, D., Varlamova, O., Cheng, H. Y. M., Marks, D., Obrietan, K., Soderling, T. R., Goodman, R. H. & Impey, S., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9093-9098 6 p.

Research output: Contribution to journalArticle

425 Scopus citations
2007

A new binding motif for the transcriptional repressor REST uncovers large gene networks devoted to neuronal functions

Otto, S. J., McCorkle, S. R., Hover, J., Conaco, C., Han, J. J., Impey, S., Yochum, G. S., Dunn, J. J., Goodman, R. H. & Mandel, G., Jun 20 2007, In : Journal of Neuroscience. 27, 25, p. 6729-6739 11 p.

Research output: Contribution to journalArticle

170 Scopus citations

Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation

Agarwal, S. K., Impey, S., McWeeney, S., Scacheri, P. C., Collins, F. S., Goodman, R. H., Spiegel, A. M. & Marx, S. J., Feb 2007, In : Neoplasia. 9, 2, p. 101-107 7 p.

Research output: Contribution to journalArticle

39 Scopus citations

Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA

Klein, M. E., Lioy, D. T., Ma, L., Impey, S., Mandel, G. & Goodman, R. H., Dec 2007, In : Nature Neuroscience. 10, 12, p. 1513-1514 2 p.

Research output: Contribution to journalArticle

340 Scopus citations

microRNA Modulation of Circadian-Clock Period and Entrainment

Cheng, H. Y. M., Papp, J. W., Varlamova, O., Dziema, H., Russell, B., Curfman, J. P., Nakazawa, T., Shimizu, K., Okamura, H., Impey, S. & Obrietan, K., Jun 7 2007, In : Neuron. 54, 5, p. 813-829 17 p.

Research output: Contribution to journalArticle

411 Scopus citations
2006

Activity-Dependent Dendritic Arborization Mediated by CaM-Kinase I Activation and Enhanced CREB-Dependent Transcription of Wnt-2

Wayman, G. A., Impey, S., Marks, D., Saneyoshi, T., Grant, W. F., Derkach, V. & Soderling, T. R., Jun 1 2006, In : Neuron. 50, 6, p. 897-909 13 p.

Research output: Contribution to journalArticle

331 Scopus citations
2005

A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis

Vo, N., Klein, M. E., Varlamova, O., Keller, D. M., Yamamoto, T., Goodman, R. H. & Impey, S., Nov 8 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 45, p. 16426-16431 6 p.

Research output: Contribution to journalArticle

642 Scopus citations

Activity-dependent neuroprotection and cAMP response element-binding protein (CREB): Kinase coupling, stimulus intensity, and temporal regulation of CREB phosphorylation at serine 133

Lee, B., Butcher, G. Q., Hoyt, K. R., Impey, S. & Obrietan, K., Feb 2 2005, In : Journal of Neuroscience. 25, 5, p. 1137-1148 12 p.

Research output: Contribution to journalArticle

137 Scopus citations

Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons

Ryu, H., Lee, J., Impey, S., Ratan, R. R. & Ferrante, R. J., Sep 27 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 39, p. 13915-13920 6 p.

Research output: Contribution to journalArticle

115 Scopus citations

CREB-mediated Bcl-2 protein expression after ischemic preconditioning

Meller, R., Minami, M., Cameron, J. A., Impey, S., Chen, D., Lan, J. Q., Henshall, D. C. & Simon, R. P., Feb 1 2005, In : Journal of Cerebral Blood Flow and Metabolism. 25, 2, p. 234-246 13 p.

Research output: Contribution to journalArticle

166 Scopus citations

Epigenetic mechanisms and gene networks in the nervous system

Colvis, C. M., Pollock, J. D., Goodman, R. H., Impey, S., Dunn, J., Mandel, G., Champagne, F. A., Mayford, M., Korzus, E., Kumar, A., Renthal, W., Theobald, D. E. H. & Nestler, E. J., Nov 9 2005, In : Journal of Neuroscience. 25, 45, p. 10379-10389 11 p.

Research output: Contribution to journalArticle

117 Scopus citations
2004

Cell-type-specific binding of the transcription factor CREB to the cAMP-response element

Cha-Molstad, H., Keller, D. M., Yochum, G. S., Impey, S. & Goodman, R. H., Sep 14 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 37, p. 13572-13577 6 p.

Research output: Contribution to journalArticle

108 Scopus citations

Defining the CREB regulon: A genome-wide analysis of transcription factor regulatory regions

Impey, S., McCorkle, S. R., Cha-Molstad, H., Dwyer, J. M., Yochum, G. S., Boss, J. M., McWeeney, S., Dunn, J. J., Mandel, G. & Goodman, R. H., Dec 29 2004, In : Cell. 119, 7, p. 1041-1054 14 p.

Research output: Contribution to journalArticle

587 Scopus citations

Mitogen- and Stress-Activated Protein Kinase 1 Mediates cAMP Response Element-Binding Protein Phosphorylation and Activation by Neurotrophins

Arthur, J. S. C., Fong, A. L., Dwyer, J. M., Davare, M., Reese, E., Obrietan, K. & Impey, S., May 5 2004, In : Journal of Neuroscience. 24, 18, p. 4324-4332 9 p.

Research output: Contribution to journalArticle

168 Scopus citations

Regulation of Axonal Extension and Growth Cone Motility by Calmodulin-Dependent Protein Kinase I

Wayman, G. A., Kaech, S., Grant, W. F., Davare, M., Impey, S., Tokumitsu, H., Nozaki, N., Banker, G. & Soderling, T. R., Apr 14 2004, In : Journal of Neuroscience. 24, 15, p. 3786-3794 9 p.

Research output: Contribution to journalArticle

136 Scopus citations
2003

Brain-derived neurotrophic factor protection of cortical neurons from serum withdrawal-induced apoptosis is inhibited by cAMP

Poser, S., Impey, S., Xia, Z. & Storm, D. R., Jun 1 2003, In : Journal of Neuroscience. 23, 11, p. 4420-4427 8 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK

Cancedda, L., Putignano, E., Impey, S., Maffei, L., Ratto, G. M. & Pizzorusso, T., Aug 6 2003, In : Journal of Neuroscience. 23, 18, p. 7012-7020 9 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Regulation of CRE-mediated transcription in mouse brain by amphetamine

Shaw-Lutchman, T. Z., Impey, S., Storm, D. & Nestler, E. J., Apr 1 2003, In : Synapse. 48, 1, p. 10-17 8 p.

Research output: Contribution to journalArticle

68 Scopus citations
2002

CREB activity in the nucleus accumbens shell controls gating of behavioral responses to emotional stimuli

Barrot, M., Olivier, J. D. A., Perrotti, L. I., DiLeone, R. J., Berton, O., Eisch, A. J., Impey, S., Storm, D. R., Neve, R. L., Yin, J. C., Zachariou, V. & Nestler, E. J., Aug 20 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 17, p. 11435-11440 6 p.

Research output: Contribution to journalArticle

388 Scopus citations

Hippocampal CRE-mediated gene expression is required for contextual memory formation

Athos, J., Impey, S., Pineda, V. V., Chen, X. & Storm, D. R., Nov 1 2002, In : Nature Neuroscience. 5, 11, p. 1119-1120 2 p.

Research output: Contribution to journalArticle

120 Scopus citations

Phosphorylation of CBP mediates transcriptional activation by neural activity and CaM kinase IV

Impey, S., Fong, A. L., Wang, Y., Cardinaux, J. R., Fass, D. M., Obrietan, K., Wayman, G. A., Storm, D. R., Soderling, T. R. & Goodman, R. H., Apr 11 2002, In : Neuron. 34, 2, p. 235-244 10 p.

Research output: Contribution to journalArticle

270 Scopus citations