Shannon McWeeney

2022

A genome-wide CRISPR screen identifies regulators of MAPK and MTOR pathways that mediate resistance to sorafenib in acute myeloid leukemia

Damnernsawad, A., Bottomly, D., Kurtz, S. E., Eide, C. A., McWeeney, S. K., Tyner, J. W. & Nechiporuk, T., Jan 2022, In: Haematologica. 107, 1, p. 77-85 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Dual BTK/SYK inhibition with CG-806 (luxeptinib) disrupts B-cell receptor and Bcl-2 signaling networks in mantle cell lymphoma

Thieme, E., Liu, T., Bruss, N., Roleder, C., Lam, V., Wang, X., Nechiporuk, T., Shouse, G., Danilova, O. V., Bottomly, D., McWeeney, S. K., Tyner, J. W., Kurtz, S. & Danilov, A., Mar 2022, In: Cell Death and Disease. 13, 3, 246.

Research output: Contribution to journal › Article › peer-review

Open Access

Functional proteomics of patient derived head and neck squamous cell carcinoma cells reveal novel applications of trametinib

Vigoda, M., Mathieson, C., Evans, N., Hale, C., Jennings, J., Lucero, O., Jeng, S., Bottomly, D., Clayburgh, D., Andersen, P., Li, R., Petrisor, D., Tyner, J. W., McWeeney, S. & Kulesz-Martin, M., 2022, In: Cancer Biology and Therapy. 23, 1, p. 310-318 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Identification and prioritization of myeloid malignancy germline variants in a large cohort of adult patients with AML

Yang, F., Long, N., Anekpuritanang, T., Bottomly, D., Savage, J. C., Lee, T., Solis-Ruiz, J., Borate, U., Wilmot, B., Tognon, C., Bock, A. M., Pollyea, D. A., Radhakrishnan, S., Radhakrishnan, S., Patel, P., Collins, R. H., Tantravahi, S., Deininger, M. W., Fan, G., Druker, B. & 5 others, Shinde, U., Tyner, J. W., Press, R. D., McWeeney, S. & Agarwal, A., Feb 24 2022, In: Blood. 139, 8, p. 1208-1221 14 p.

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

MS4A3 promotes differentiation in chronic myeloid leukemia by enhancing common β-chain cytokine receptor endocytosis

Zhao, H., Pomicter, A. D., Eiring, A. M., Franzini, A., Ahmann, J., Hwang, J. Y., Senina, A., Helton, B., Iyer, S., Yan, D., Khorashad, J. S., Zabriskie, M. S., Agarwal, A., Redwine, H. M., Bowler, A. D., Clair, P. M., McWeeney, S. K., Druker, B. J., Tyner, J. W., Stirewalt, D. L. & 8 others, Oehler, V. G., Varambally, S., Berrett, K. C., Vahrenkamp, J. M., Gertz, J., Varley, K. E., Radich, J. P. & Deininger, M. W., Feb 3 2022, In: Blood. 139, 5, p. 761-778 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2021

Baseline T cell immune phenotypes predict virologic and disease control upon SARS-CoV infection in Collaborative Cross mice

Graham, J. B., Swarts, J. L., Leist, S. R., Schäfer, A., Menachery, V. D., Gralinski, L. E., Jeng, S., Miller, D. R., Mooney, M. A., McWeeney, S. K., Ferris, M. T., de Villena, F. P. M., Heise, M. T., Baric, R. S. & Lund, J. M., Jan 29 2021, In: PLoS pathogens. 17, 1, e1009287.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Dopamine neuron-specific LRRK2 G2019S effects on gene expression revealed by translatome profiling

Pallos, J., Jeng, S., McWeeney, S. & Martin, I., Jul 2021, In: Neurobiology of Disease. 155, 105390.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Incorporating immunoproteins in the development of classification models of progression of intracranial hemorrhage after traumatic brain injury

Hinson, H. E., Li, P., Myers, L., Agarwal, C., Pollock, J. & McWeeney, S., Sep 2021, In: Journal of Head Trauma Rehabilitation. 36, 5, p. E322-E328

Research output: Contribution to journal › Article › peer-review

Lentiviral-driven discovery of cancer drug resistance mutations

Yenerall, P., Kollipara, R. K., Avila, K., Peyton, M., Eide, C. A., Bottomly, D., McWeeney, S. K., Liu, Y., Westover, K. D., Druker, B. J., Minna, J. D. & Kittler, R., Sep 15 2021, In: Cancer Research. 81, 18, p. 4685-4695 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5a Promotes Cancer Invasion and Tumor Growth

Iizuka, S., Quintavalle, M., Navarro, J. C., Gribbin, K. P., Ardecky, R. J., Abelman, M. M., Ma, C. T., Sergienko, E., Zeng, F. Y., Pass, I., Thomas, G. V., McWeeney, S. K., Hassig, C. A., Pinkerton, A. B. & Courtneidge, S. A., Mar 2021, In: Cancer Research. 81, 6, p. 1472-1485 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance

Joshi, S. K., Nechiporuk, T., Bottomly, D., Piehowski, P. D., Reisz, J. A., Pittsenbarger, J., Kaempf, A., Gosline, S. J. C., Wang, Y. T., Hansen, J. R., Gritsenko, M. A., Hutchinson, C., Weitz, K. K., Moon, J., Cendali, F., Fillmore, T. L., Tsai, C. F., Schepmoes, A. A., Shi, T., Arshad, O. A. & 12 others, McDermott, J. E., Babur, O., Watanabe-Smith, K., Demir, E., D'Alessandro, A., Liu, T., Tognon, C. E., Tyner, J. W., McWeeney, S. K., Rodland, K. D., Druker, B. J. & Traer, E., Jul 12 2021, In: Cancer Cell. 39, 7, p. 999-1014.e8

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

2020

A Systematic Framework to Rapidly Obtain Data on Patients with Cancer and COVID-19: CCC19 Governance, Protocol, and Quality Assurance

The COVID-19 and Cancer Consortium, Dec 14 2020, In: Cancer Cell. 38, 6, p. 761-766 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

10 Scopus citations

AZD4320, a dual inhibitor of bcl-2 and bcl-x_l, induces tumor regression in hematologic cancer models without dose-limiting thrombocytopenia

Balachander, S. B., Criscione, S. W., Byth, K. F., Cidado, J., Adam, A., Lewis, P., Macintyre, T., Wen, S., Lawson, D., Burke, K., Lubinski, T., Tyner, J. W., Kurtz, S. E., McWeeney, S. K., Varnes, J., Diebold, R. B., Gero, T., Ioannidis, S., Hennessy, E. J., McCoull, W. & 18 others, Saeh, J. C., Tabatabai, A., Tavana, O., Su, N., Schuller, A., Garnett, M. J., Jaaks, P., Coker, E. A., Gregory, G. P., Newbold, A., Johnstone, R. W., Gangl, E., Wild, M., Zinda, M., Secrist, J. P., Davies, B. R., Fawell, S. E. & Gibbons, F. D., Dec 2020, In: Clinical Cancer Research. 26, 24, p. 6535-6549 15 p.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Chronic Voluntary Ethanol Drinking in Cynomolgus Macaques Elicits Gene Expression Changes in Prefrontal Cortical Area 46

Walter, N. A. R., Zheng, C. L., Searles, R. P., McWeeney, S. K., Grant, K. A. & Hitzemann, R., Feb 1 2020, In: Alcoholism: Clinical and Experimental Research. 44, 2, p. 470-478 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer

Burfeind, K. G., Zhu, X., Norgard, M. A., Levasseur, P. R., Huisman, C., Buenafe, A. C., Olson, B., Michaelis, K. A., Torres, E. R. S., Jeng, S., McWeeney, S., Raber, J. & Marks, D. L., May 2020, In: eLife. 9, p. 1-27 27 p., e54095.

Research output: Contribution to journal › Article › peer-review

Open Access

13 Scopus citations

Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study

COVID-19 and Cancer Consortium, Jun 20 2020, In: The Lancet. 395, 10241, p. 1907-1918 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

796 Scopus citations

Complex Genetic Architecture Underlies Regulation of Influenza-A-Virus-Specific Antibody Responses in the Collaborative Cross

Noll, K. E., Whitmore, A. C., West, A., McCarthy, M. K., Morrison, C. R., Plante, K. S., Hampton, B. K., Kollmus, H., Pilzner, C., Leist, S. R., Gralinski, L. E., Menachery, V. D., Schäfer, A., Miller, D., Shaw, G., Mooney, M., McWeeney, S., Pardo-Manuel de Villena, F., Schughart, K., Morrison, T. E. & 3 others, Baric, R. S., Ferris, M. T. & Heise, M. T., Apr 28 2020, In: Cell Reports. 31, 4, 107587.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Discovery and characterization of targetable NTRK point mutations in hematologic neoplasms

Joshi, S. K., Qian, K., Bisson, W. H., Watanabe-Smith, K., Huang, A., Bottomly, D., Traer, E., Tyner, J. W., McWeeney, S. K., Davare, M. A., Druker, B. J. & Tognon, C. E., Jun 11 2020, In: Blood. 135, 24, p. 2159-2170 12 p.

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

ERBB2/HER2 mutations are transforming and therapeutically targetable in leukemia

Joshi, S. K., Keck, J. M., Eide, C. A., Bottomly, D., Traer, E., Tyner, J. W., McWeeney, S. K., Tognon, C. E. & Druker, B. J., Oct 1 2020, In: Leukemia. 34, 10, p. 2798-2804 7 p.

Research output: Contribution to journal › Article › peer-review

Open Access

5 Scopus citations

Functional genomic analysis identifies drug targetable pathways in invasive and metastatic cutaneous squamous cell carcinoma

Anderson, A. N., McClanahan, D., Jacobs, J., Jeng, S., Vigoda, M., Blucher, A. S., Zheng, C., Yoo, Y. J., Hale, C., Ouyang, X., Clayburgh, D., Andersen, P., Tyner, J. W., Bar, A., Lucero, O. M., Leitenberger, J. J., McWeeney, S. K. & Kulesz-Martin, M., Aug 2020, In: Cold Spring Harbor Molecular Case Studies. 6, 4, a005439.

Research output: Contribution to journal › Article › peer-review

Open Access

3 Scopus citations

Immune Predictors of Mortality after Ribonucleic Acid Virus Infection

Graham, J. B., Swarts, J. L., Menachery, V. D., Gralinski, L. E., Schäfer, A., Plante, K. S., Morrison, C. R., Voss, K. M., Green, R., Choonoo, G., Jeng, S., Miller, D. R., Mooney, M. A., McWeeney, S. K., Ferris, M. T., De Villena, F. P. M., Gale, M., Heise, M. T., Baric, R. S. & Lund, J. M., Mar 15 2020, In: Journal of Infectious Diseases. 221, 6, p. 882-889 8 p.

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Integrated analysis of patient samples identifies biomarkers for venetoclax efficacy and combination strategies in acute myeloid leukemia

Zhang, H., Nakauchi, Y., Köhnke, T., Stafford, M., Bottomly, D., Thomas, R., Wilmot, B., McWeeney, S. K., Majeti, R. & Tyner, J. W., Aug 1 2020, In: Nature Cancer. 1, 8, p. 826-839 14 p.

Research output: Contribution to journal › Article › peer-review

35 Scopus citations

In Vivo Repair of a Protein Underlying a Neurological Disorder by Programmable RNA Editing

Sinnamon, J. R., Kim, S. Y., Fisk, J. R., Song, Z., Nakai, H., Jeng, S., McWeeney, S. K. & Mandel, G., Jul 14 2020, In: Cell Reports. 32, 2, 107878.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Reversible suppression of T cell function in the bone marrow microenvironment of acute myeloid leukemia

Lamble, A. J., Kosaka, Y., Laderas, T., Maffit, A., Kaempf, A., Brady, L. K., Wang, W., Long, N., Saultz, J. N., Mori, M., Soong, D., LeFave, C. V., Huang, F., Adams, H., Loriaux, M. M., Loriaux, M. M., Tognon, C. E., Lo, P., Tyner, J. W., Tyner, J. W. & 6 others, Fan, G., McWeeney, S. K., Druker, B. J., Lind, E. F., Lind, E. F. & Lind, E. F., Jun 23 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 25, p. 14331-14341 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Subcellular localization of FANCD2 is associated with survival in ovarian carcinoma

Joshi, S., Campbell, S., Lim, J. Y., McWeeney, S., Krieg, A., Bean, Y., Pejovic, N., Mhawech-Fauceglia, P. & Pejovic, T., Feb 25 2020, In: Oncotarget. 11, 8, p. 775-783 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

2019

Acute myeloid leukemia–induced T-cell suppression can be reversed by inhibition of the MAPK pathway

Moshofsky, K. B., Cho, H. J., Wu, G., Romine, K. A., Newman, M. T., Kosaka, Y., McWeeney, S. K. & Lind, E. F., Oct 22 2019, In: Blood Advances. 3, 20, p. 3038-3051 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

6 Scopus citations

ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants

Luo, X., Feurstein, S., Mohan, S., Porter, C. C., Jackson, S. A., Keel, S., Chicka, M., Brown, A. L., Kesserwan, C., Agarwal, A., Luo, M., Li, Z., Ross, J. E., Baliakas, P., Pineda-Alvarez, D., DiNardo, C. D., Bertuch, A. A., Mehta, N., Vulliamy, T., Wang, Y. & 14 others, Nichols, K. E., Malcovati, L., Walsh, M. F., Rawlings, L. H., McWeeney, S. K., Soulier, J., Raimbault, A., Routbort, M. J., Zhang, L., Ryan, G., Speck, N. A., Plon, S. E., Wu, D. & Godley, L. A., Oct 22 2019, In: Blood Advances. 3, 20, p. 2962-2979 18 p.

Research output: Contribution to journal › Article › peer-review

Open Access

54 Scopus citations

Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms

Zhang, H., Savage, S., Schultz, A. R., Bottomly, D., White, L., Segerdell, E., Wilmot, B., McWeeney, S. K., Eide, C. A., Nechiporuk, T., Carlos, A., Henson, R., Lin, C., Searles, R., Ho, H., Lam, Y. L., Sweat, R., Follit, C., Jain, V., Lind, E. & 10 others, Borthakur, G., Garcia-Manero, G., Ravandi, F., Kantarjian, H. M., Cortes, J., Collins, R., Buelow, D. R., Baker, S. D., Druker, B. J. & Tyner, J. W., Dec 1 2019, In: Nature communications. 10, 1, 244.

Research output: Contribution to journal › Article › peer-review

Open Access

64 Scopus citations

Controlling for contaminants in low-biomass 16S rRNA gene sequencing experiments

Karstens, L., Asquith, M., Davin, S., Fair, D., Gregory, W. T., Wolfe, A. J., Braun, J. & McWeeney, S., Jul 2019, In: mSystems. 4, 4, e00290-19.

Research output: Contribution to journal › Article › peer-review

Open Access

82 Scopus citations

CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells

Edwards, D. K., Watanabe-Smith, K., Rofelty, A., Damnernsawad, A., Laderas, T., Lamble, A., Lind, E. F., Kaempf, A., Mori, M., Rosenberg, M., d’Almeida, A., Long, N., Agarwal, A., Sweeney, D. T., Loriaux, M., McWeeney, S. K. & Tyner, J. W., Feb 7 2019, In: Blood. 133, 6, p. 588-599 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

53 Scopus citations

Genomic landscape of neutrophilic leukemias of ambiguous diagnosis

Zhang, H., Wilmot, B., Bottomly, D., Dao, K-H., Stevens, E., Eide, C. A., Khanna, V., Rofelty, A., Savage, S., Schultz, A. R., Long, N., White, L., Carlos, A., Henson, R., Lin, C., Searles, R., Collins, R. H., DeAngelo, D. J., Deininger, M. W., Dunn, T. & 12 others, Hein, T., Luskin, M. R., Medeiros, B. C., Oh, S. T., Pollyea, D. A., Steensma, D. P., Stone, R. M., Druker, B. J., McWeeney, S. K., Maxson, J. E., Gotlib, J. R. & Tyner, J. W., Sep 12 2019, In: Blood. 134, 11, p. 867-879 13 p.

Research output: Contribution to journal › Article › peer-review

Open Access

33 Scopus citations

Illuminating biological pathways for drug targeting in head and neck squamous cell carcinoma

Choonoo, G., Blucher, A. S., Higgins, S., Boardman, M., Jeng, S., Zheng, C., Jacobs, J., Anderson, A., Chamberlin, S., Evans, N., Vigoda, M., Cordier, B., Tyner, J. W., Kulesz-Martin, M., McWeeney, S. K. & Laderas, T., Oct 1 2019, In: PloS one. 14, 10, e0223639.

Research output: Contribution to journal › Article › peer-review

Open Access

1 Scopus citations

Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia

Braun, T. P., Okhovat, M., Coblentz, C., Carratt, S. A., Foley, A., Schonrock, Z., Smith, B. M., Nevonen, K., Davis, B., Garcia, B., LaTocha, D., Weeder, B. R., Grzadkowski, M. R., Estabrook, J. C., Manning, H. G., Watanabe-Smith, K., Jeng, S., Smith, J. L., Leonti, A. R., Ries, R. E. & 8 others, McWeeney, S., Di Genua, C., Drissen, R., Nerlov, C., Meshinchi, S., Carbone, L., Druker, B. J. & Maxson, J. E., Dec 1 2019, In: Nature communications. 10, 1, 5455.

Research output: Contribution to journal › Article › peer-review

Open Access

14 Scopus citations

Natural product target network reveals potential for cancer combination therapies

Chamberlin, S. R., Blucher, A., Wu, G., Shinto, L., Choonoo, G., Kulesz-Martin, M. & McWeeney, S., 2019, In: Frontiers in Pharmacology. 10, MAY, 557.

Research output: Contribution to journal › Article › peer-review

Open Access

22 Scopus citations

Persistent Toll-like receptor 7 stimulation induces behavioral and molecular innate immune tolerance

Michaelis, K. A., Norgard, M. A., Levasseur, P. R., Olson, B., Burfeind, K. G., Buenafe, A. C., Zhu, X., Jeng, S., McWeeney, S. K. & Marks, D. L., Nov 2019, In: Brain, Behavior, and Immunity. 82, p. 338-353 16 p.

Research output: Contribution to journal › Article › peer-review

Open Access

18 Scopus citations

Predicting response to BET inhibitors using computational modeling: A BEAT AML project study

Drusbosky, L. M., Vidva, R., Gera, S., Lakshminarayana, A. V., Shyamasundar, V. P., Agrawal, A. K., Talawdekar, A., Abbasi, T., Vali, S., Tognon, C. E., Kurtz, S., Tyner, J. W., McWeeney, S. K., Druker, B. J. & Cogle, C. R., Feb 2019, In: Leukemia Research. 77, p. 42-50 9 p.

Research output: Contribution to journal › Article › peer-review

Open Access

7 Scopus citations

Salt-sensitive transcriptome of isolated kidney distal tubule cells

Swanson, E. A., Nelson, J. W., Jeng, S., Erspamer, K. J., Yang, C. L., McWeeney, S. & Ellison, D. H., Apr 2019, In: Physiological genomics. 51, 4, p. 125-135 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2 Scopus citations

The TP53 apoptotic network is a primary mediator of resistance to BCL2 inhibition in AML cells

Nechiporuk, T., Kurtz, S., Nikolova, O., Liu, T., Jones, C. L., D’alessandro, A., Culp-Hill, R., D’almeida, A., Joshi, S. K., Rosenberg, M., Tognon, C. E., Danilov, A., Druker, B. J., Chang, B. H., McWeeney, S. K. & Tyner, J. W., Jul 2019, In: Cancer discovery. 9, 7, p. 910-925 16 p.

Research output: Contribution to journal › Article › peer-review

91 Scopus citations

2018

A single-cell approach to the elusive latent human cytomegalovirus transcriptome

Goodrum, F. & McWeeney, S., May 1 2018, In: mBio. 9, 3, e01001-18.

Research output: Contribution to journal › Article › peer-review

Open Access

4 Scopus citations

Functional genomic landscape of acute myeloid leukaemia

Tyner, J. W., Tognon, C. E., Bottomly, D., Wilmot, B., Kurtz, S. E., Savage, S. L., Long, N., Schultz, A. R., Traer, E., Abel, M., Agarwal, A., Blucher, A., Borate, U., Bryant, J., Burke, R., Carlos, A., Carpenter, R., Carroll, J., Chang, B. H., Coblentz, C. & 68 others, d’Almeida, A., Cook, R., Danilov, A., Dao, K. H. T., Degnin, M., Devine, D., Dibb, J., Edwards, D. K., Eide, C. A., English, I., Glover, J., Henson, R., Ho, H., Jemal, A., Johnson, K., Johnson, R., Junio, B., Kaempf, A., Leonard, J., Lin, C., Liu, S. Q., Lo, P., Loriaux, M. M., Luty, S., Macey, T., MacManiman, J., Martinez, J., Mori, M., Nelson, D., Nichols, C., Peters, J., Ramsdill, J., Rofelty, A., Schuff, R., Searles, R., Segerdell, E., Smith, R. L., Spurgeon, S. E., Sweeney, T., Thapa, A., Visser, C., Wagner, J., Watanabe-Smith, K., Werth, K., Wolf, J., White, L., Yates, A., Zhang, H., Cogle, C. R., Collins, R. H., Connolly, D. C., Deininger, M. W., Drusbosky, L., Hourigan, C. S., Jordan, C. T., Kropf, P., Lin, T. L., Martinez, M. E., Medeiros, B. C., Pallapati, R. R., Pollyea, D. A., Swords, R. T., Watts, J. M., Weir, S. J., Wiest, D. L., Winters, R. M., McWeeney, S. K. & Druker, B. J., Oct 25 2018, In: Nature. 562, 7728, p. 526-531 6 p.

Research output: Contribution to journal › Article › peer-review

371 Scopus citations

Gender-Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Noncoding RNAs

Iancu, O., Colville, A. M., Wilmot, B., Searles, R., Darakjian, P., Zheng, C., McWeeney, S., Kawane, S., Crabbe, J. J., Metten, P., Oberbeck, D. & Hitzemann, R., Aug 2018, In: Alcoholism: Clinical and Experimental Research. 42, 8, p. 1454-1465 12 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Induction of anaplastic lymphoma kinase (ALK) as a novel mechanism of EGFR inhibitor resistance in head and neck squamous cell carcinoma patient-derived models

Ouyang, X., Barling, A., Lesch, A., Tyner, J. W., Choonoo, G., Zheng, C., Jeng, S., West, T. M., Clayburgh, D., Courtneidge, S. A., McWeeney, S. K. & Kulesz-Martin, M., Oct 3 2018, In: Cancer Biology and Therapy. 19, 10, p. 921-933 13 p.

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Integrated functional and mass spectrometry-based flow cytometric phenotyping to describe the immune microenvironment in acute myeloid leukemia

Lamble, A. J., Dietz, M., Laderas, T., McWeeney, S. & Lind, E. F., Feb 2018, In: Journal of Immunological Methods. 453, p. 44-52 9 p.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

LSD1 activates a lethal prostate cancer gene network independently of its demethylase function

Sehrawat, A., Gao, L., Wang, Y., Bankhead, A., McWeeney, S. K., King, C. J., Schwartzman, J., Urrutia, J., Bisson, W. H., Coleman, D. J., Joshi, S. K., Kim, D. H., Sampson, D. A., Weinmann, S., Kallakury, B. V. S., Berry, D. L., Haque, R., Van Den Eeden, S. K., Sharma, S., Bearss, J. & 4 others, Beer, T. M., Thomas, G. V., Heiser, L. M. & Alumkal, J., May 1 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 18, p. E4179-E4188

Research output: Contribution to journal › Article › peer-review

Open Access

89 Scopus citations

Network-based predictors of progression in head and neck squamous cell carcinoma

Sanati, N., Iancu, O., Wu, G., Jacobs, J. E. & McWeeney, S. K., May 29 2018, In: Frontiers in Genetics. 9, MAY, 183.

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

On the relationships in rhesus macaques between chronic ethanol consumption and the brain transcriptome

Iancu, O., Colville, A., Walter, N. A. R., Darakjian, P., Oberbeck, D. L., Daunais, J. B., Zheng, C. L., Searles, R. P., McWeeney, S. K., Grant, K. A. & Hitzemann, R., Jan 2018, In: Addiction Biology. 23, 1, p. 196-205 10 p.

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Regional differences and similarities in the brain transcriptome for mice selected for ethanol preference from HS-CC founders

Colville, A. M., Iancu, O., Lockwood, D. R., Darakjian, P., McWeeney, S. K., Searles, R., Zheng, C. & Hitzemann, R., Aug 28 2018, In: Frontiers in Genetics. 9, AUG, 300.

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia

Jenkins, C., Luty, S. B., Maxson, J. E., Eide, C. A., Abel, M. L., Togiai, C., Nemecek, E. R., Bottomly, D., McWeeney, S. K., Wilmot, B., Loriaux, M., Chang, B. H. & Tyner, J. W., Jul 17 2018, In: Science signaling. 11, 539, eaao5617.

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples

Edwards V, D. K., Sweeney, D. T., Ho, H., Eide, C. A., Rofelty, A., Agarwal, A., Liu, S. Q., Danilov, A., Lee, P., Chantry, D., McWeeney, S. K., Druker, B. J., Tyner, J. W., Spurgeon, S. E. & Loriaux, M. M., May 15 2018, In: Oncotarget. 9, 37, p. 24576-24589 14 p.

Research output: Contribution to journal › Article › peer-review

Open Access

24 Scopus citations

Working Memory and Vigilance as Multivariate Endophenotypes Related to Common Genetic Risk for Attention-Deficit/Hyperactivity Disorder

Nigg, J. T., Gustafsson, H. C., Karalunas, S., Ryabinin, P., McWeeney, S. K., Faraone, S. V., Mooney, M. A., Fair, D. & Wilmot, B., Mar 2018, In: Journal of the American Academy of Child and Adolescent Psychiatry. 57, 3, p. 175-182 8 p.

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Shannon McWeeney

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