Sergio Ojeda

Professor

  • 17308 Citations
  • 72 h-Index
1969 …2020
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Research Output 1969 2019

  • 17308 Citations
  • 72 h-Index
  • 335 Article
  • 6 Chapter
  • 1 Conference contribution
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Article
1996
69 Citations (Scopus)

Involvement of nerve growth factor in the ovulatory cascade: trkA receptor activation inhibits gap junctional communication between thecal cells

Mayerhofer, A., Dissen, G., Parrott, J. A., Hill, D. F., Mayerhofer, D., Garfield, R. E., Costa, M. E., Skinner, M. K. & Ojeda, S., 1996, In : Endocrinology. 137, 12, p. 5662-5670 9 p.

Research output: Contribution to journalArticle

trkA Receptor
Nerve Growth Factor
Gap Junctions
Rupture
Ovulation
65 Citations (Scopus)

Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons

Voigt, P., Ma, Y. J., Gonzalez, D., Fahrenbach, W. H., Wetsel, W. C., Berg-Von Der Emde, K., Hill, D. F., Taylor, K. G., Costa, M. E., Seidah, N. G. & Ojeda, S., 1996, In : Endocrinology. 137, 6, p. 2593-2605 13 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Gonadotropin-Releasing Hormone
Neuroglia
Intercellular Signaling Peptides and Proteins
Neurons
15 Citations (Scopus)

Participation of nerve growth factor in the regulation of ovarian function

Dissen, G., Mayerhofer, A. & Ojeda, S., Nov 1996, In : Zygote. 4, 4, p. 309-312 4 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins
trkA Receptor
Theca Cells
Nerve Growth Factor Receptors
Gap Junctions
36 Citations (Scopus)

RNase protection assay

Ma, Y. J., Dissen, G., Rage, F. & Ojeda, S., Dec 1996, In : Methods: A Companion to Methods in Enzymology. 10, 3, p. 273-278 6 p.

Research output: Contribution to journalArticle

Ribonucleases
Assays
Messenger RNA
Complementary RNA
RNA
34 Citations (Scopus)

Testis of prepubertal rhesus monkeys receives a dual catecholaminergic input provided by the extrinsic innervation and an intragonadal source of catecholamines

Mayerhofer, A., Danilchik, M., Pau, K. Y. F., Lara, H. E., Russell, L. D. & Ojeda, S., Sep 1996, In : Biology of Reproduction. 55, 3, p. 509-518 10 p.

Research output: Contribution to journalArticle

Macaca mulatta
Catecholamines
Testis
Gonads
Primates
1995
133 Citations (Scopus)

Expression of neurotrophins and their receptors in the mammalian ovary is developmentally regulated: Changes at the time of folliculogenesis

Dissen, G., Hirshfield, A. N., Malamed, S. & Ojeda, S., 1995, In : Endocrinology. 136, 10, p. 4681-4692 12 p.

Research output: Contribution to journalArticle

Nerve Growth Factor Receptors
Ovary
Nerve Growth Factor Receptor
Nerve Growth Factor
Nerve Growth Factors
68 Citations (Scopus)

Neurotrophins and the neuroendocrine brain: Different neurotrophins sustain anatomically and functionally segregated subsets of hypothalamic dopaminergic neurons

Berg-Von der Emde, K., Dees, W. L., Hiney, J. K., Hill, D. F., Dissen, G., Costa, M. E., Moholt-Siebert, M. & Ojeda, S., 1995, In : Journal of Neuroscience. 15, 6, p. 4223-4237 15 p.

Research output: Contribution to journalArticle

Dopaminergic Neurons
Nerve Growth Factors
Neurons
Brain
Tyrosine
65 Citations (Scopus)

The primate ovary contains a population of catecholaminergic neuron-like cells expressing nerve growth factor receptors

Les Dees, W., Hiney, J. K., Schultea, T. D., Mayerhofer, A., Danilchik, M., Dissen, G. & Ojeda, S., 1995, In : Endocrinology. 136, 12, p. 5760-5768 9 p.

Research output: Contribution to journalArticle

Nerve Growth Factor Receptors
Primates
Ovary
Neurons
Population
1994
171 Citations (Scopus)

Androgens regulate aromatase cytochrome P450 messenger ribonucleic acid in rat brain

Abdelgadir, S. E., Resko, J. A., Ojeda, S., Lephart, E. D., Mcphaul, M. J. & Roselli, C., Jul 1994, In : Endocrinology. 135, 1, p. 395-401 7 p.

Research output: Contribution to journalArticle

Aromatase
Cytochrome P-450 Enzyme System
Androgens
RNA
Messenger RNA
95 Citations (Scopus)

Developmental expression of the genes encoding transforming growth factor alpha and its receptor in the hypothalamus of female rhesus macaques

Ma, Y. J., Costa, M. E. & Ojeda, S., 1994, In : Neuroendocrinology. 60, 4, p. 346-359 14 p.

Research output: Contribution to journalArticle

Developmental Genes
Transforming Growth Factor alpha
Macaca mulatta
Epidermal Growth Factor Receptor
Hypothalamus
16 Citations (Scopus)

Developmental regulation of the ovary via growth factor tyrosine kinase receptors

Ojeda, S. & Dissen, G., 1994, In : Trends in Endocrinology and Metabolism. 5, 8, p. 317-323 7 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Ovary
Intercellular Signaling Peptides and Proteins
Fibroblast Growth Factors
Nerve Growth Factors
87 Citations (Scopus)

Expression of epidermal growth factor receptor changes in the hypothalamus during the onset of female puberty

Ma, Y. J., Hill, D. F., Junier, M. P., Costa, M. E., Felder, S. E. & Ojeda, S., 1994, In : Molecular and Cellular Neurosciences. 5, 3, p. 246-262 17 p.

Research output: Contribution to journalArticle

Puberty
Epidermal Growth Factor Receptor
Hypothalamus
Gonadotropin-Releasing Hormone
Median Eminence
183 Citations (Scopus)

Immature rat ovaries become revascularized rapidly after autotransplantation and show a gonadotropin-dependent increase in angiogenic factor gene expression

Dissen, G., Lara, H. E., Fahrenbach, W. H., Costa, M. E. & Ojeda, S., 1994, In : Endocrinology. 134, 3, p. 1146-1154 9 p.

Research output: Contribution to journalArticle

Autologous Transplantation
Angiogenesis Inducing Agents
Gonadotropins
Ovary
Gene Expression
54 Citations (Scopus)

Overexpression of a human transforming growth factor-alpha (TGF alpha) transgene reveals a dual antagonistic role of TGF alpha in female sexual development

Jun Ma, Y., Dissen, G., Merlino, G., Coquelin, A. & Ojeda, S., 1994, In : Endocrinology. 135, 4, p. 1392-1400 9 p.

Research output: Contribution to journalArticle

Transforming Growth Factor alpha
Sexual Development
Gonadotropins
Transgenes
Estrus
91 Citations (Scopus)

Region-specific regulation of transforming growth factor α (TGFα) gene expression in astrocytes of the neuroendocrine brain

Ma, Y. J., Berg-Von Der Emde, K., Moholt-Siebert, M., Hill, D. F. & Ojeda, S., Sep 1994, In : Journal of Neuroscience. 14, 9, p. 5644-5651 8 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Astrocytes
Gene Expression
Brain
Neuroglia
1993
168 Citations (Scopus)

Activation of ovarian sympathetic nerves in polycystic ovary syndrome

Lara, H. E., Ferruz, J. L., Luza, S., Bustamante, D. A., Ojeda, S. & Ojeda, S. R., Dec 1993, In : Endocrinology. 133, 6, p. 2690-2695 6 p.

Research output: Contribution to journalArticle

estradiol valerate
Polycystic Ovary Syndrome
Ovary
Cysts
Norepinephrine
11 Citations (Scopus)

Estradiol increases neural-specific class II-β-tubulin mRNA levels in the developing female hypothalamus by regulating mRNA stability

Rogers, L. C., De Boer, I., Junier, M. P. & Ojeda, S., 1993, In : Molecular and Cellular Neuroscience. 4, 5, p. 424-431 8 p.

Research output: Contribution to journalArticle

RNA Stability
Tubulin
Hypothalamus
Estradiol
Messenger RNA
63 Citations (Scopus)
erbB-1 Genes
Precocious Puberty
Neuroglia
Gonadotropin-Releasing Hormone
Transforming Growth Factors
128 Citations (Scopus)

Ovarian steroidal response to gonadotropins and β-adrenergic stimulation is enhanced in polycystic ovary syndrome: Role of sympathetic innervation

Barria, A., Leyton, V., Ojeda, S. & Lara, H. E., Dec 1993, In : Endocrinology. 133, 6, p. 2696-2703 8 p.

Research output: Contribution to journalArticle

estradiol valerate
Polycystic Ovary Syndrome
Gonadotropins
Adrenergic Agents
Ovary
1992
107 Citations (Scopus)

Brain aromatase cytochrome P-450 messenger RNA levels and enzyme activity during prenatal and perinatal development in the rat

Lephart, E. D., Simpson, E. R., McPhaul, M. J., Kilgore, M. W., Wilson, J. D. & Ojeda, S., 1992, In : Molecular Brain Research. 16, 3-4, p. 187-192 6 p.

Research output: Contribution to journalArticle

Aromatase
Cytochrome P-450 Enzyme System
Messenger RNA
Brain
Enzymes
21 Citations (Scopus)

Detection of Nerve Growth Factor and One of Its Receptors

Hill, D. F., Dissen, G., Ma, Y. J. & Ojeda, S., Jan 1 1992, In : Methods in Neurosciences. 9, C, p. 179-196 18 p.

Research output: Contribution to journalArticle

Nerve Growth Factor
Ribonucleases
Messenger RNA
Digestion
RNA Probes
30 Citations (Scopus)

Effect of hypothalamic lesions that induce precocious puberty on the morphological and functional maturation of the luteinizing hormone-releasing hormone neuronal system

Junier, M. P., Wolff, A., Hoffman, G. E., Ma, Y. J. & Ojeda, S., Aug 1992, In : Endocrinology. 131, 2, p. 787-798 12 p.

Research output: Contribution to journalArticle

Precocious Puberty
Gonadotropin-Releasing Hormone
Neurons
Anterior Hypothalamic Nucleus
Proestrus
48 Citations (Scopus)

Effects of cyclic AMP and androgens on in vitro brain aromatase enzyme activity during prenatal development in the rat

Lephart, E. D., Simpson, E. R. & Ojeda, S., 1992, In : Journal of Neuroendocrinology. 4, 1, p. 29-35 7 p.

Research output: Contribution to journalArticle

Aromatase
Cyclic AMP
Steroids
Brain
Enzymes
55 Citations (Scopus)

Neurotrophic factors and female sexual development

Ojeda, S., Dissen, G. & Junier, M. P., 1992, In : Frontiers in Neuroendocrinology. 13, 2, p. 120-162 43 p.

Research output: Contribution to journalArticle

Sexual Development
Nerve Growth Factors
Transforming Growth Factors
Hypothalamus
Gonadotropin-Releasing Hormone
20 Citations (Scopus)

Norepinephrine release in the immature ovary is regulated by autoreceptors and neuropeptide-Y

Ferruz, J., Ahmed, C. E., Ojeda, S. & Lara, H. E., Mar 1992, In : Endocrinology. 130, 3, p. 1345-1351 7 p.

Research output: Contribution to journalArticle

Autoreceptors
Neuropeptide Y
Ovary
Norepinephrine
Adrenergic Agents
51 Citations (Scopus)

Ovarian innervation develops before initiation of folliculogenesis in the rat

Malamed, S., Gibney, J. A. & Ojeda, S., Oct 1992, In : Cell & Tissue Research. 270, 1, p. 87-93 7 p.

Research output: Contribution to journalArticle

Gonadotropins
Rats
Ovary
Fibers
Biosynthesis
32 Citations (Scopus)

Postnatal development of sympathetic and sensory innervation of the rhesus monkey ovary

Schultea, T. D., Les Dees, W. & Ojeda, S., 1992, In : Biology of Reproduction. 47, 5, p. 760-767 8 p.

Research output: Contribution to journalArticle

Vasoactive Intestinal Peptide
Macaca mulatta
Ovary
Neuropeptide Y
Tyrosine 3-Monooxygenase

PUBERTE PRECOCE APRES LESIONS HYPOTHALAMIQUES: ROLE DU TGF∅

Translated title of the contribution: Transforming growth factor α is involved in precocious puberty induced by hypothalamic injuryJunier, M. P. & Ojeda, S., 1992, In : Medecine/Sciences. 8, 3, p. 259-261 3 p.

Research output: Contribution to journalArticle

Precocious Puberty
Transforming Growth Factor alpha
Wounds and Injuries
176 Citations (Scopus)

Transforming growth factor-α gene expression in the hypothalamus is developmentally regulated and linked to sexual maturation

Jun Ma, Y., Junier, M. P., Costa, M. E. & Ojeda, S., 1992, In : Neuron. 9, 4, p. 657-670 14 p.

Research output: Contribution to journalArticle

Sexual Maturation
Transforming Growth Factors
Hypothalamus
Gonadotropin-Releasing Hormone
Gene Expression
1991
21 Citations (Scopus)

A sex-related difference in the developmental expression of class II β-tubulin messenger RNA in rat hypothalamus

Rogers, L. C., Junier, M. P., Farmer, S. R. & Ojeda, S., 1991, In : Molecular and Cellular Neuroscience. 2, 2, p. 130-138 9 p.

Research output: Contribution to journalArticle

Tubulin
Sex Characteristics
Hypothalamus
Middle Hypothalamus
Messenger RNA
43 Citations (Scopus)

Functional recovery of the developing rat ovary after transplantation: Contribution of the extrinsic innervation

Lara, H. E., Dees, W. L., Hiney, J. K., Dissen, G., Rivier, C. & Ojeda, S., Oct 1991, In : Endocrinology. 129, 4, p. 1849-1860 12 p.

Research output: Contribution to journalArticle

Ovary
Transplantation
Serum
Inhibins
Calcitonin Gene-Related Peptide
173 Citations (Scopus)

Insulin-like growth factor i: A possible metabolic signal involved in the regulation of female puberty

Hiney, J. K., Ojeda, S. & Dees, W. L., 1991, In : Neuroendocrinology. 54, 4, p. 420-423 4 p.

Research output: Contribution to journalArticle

Somatomedins
Puberty
Insulin-Like Growth Factor I
Gonadotropin-Releasing Hormone
Hypothalamic Hormones
53 Citations (Scopus)

Nerve growth factor receptors in the peripubertal rat ovary

Dissen, G., Hill, D. F., Costa, M. E., Ma, Y. J. & Ojeda, S., 1991, In : Molecular Endocrinology. 5, 11, p. 1642-1650 9 p.

Research output: Contribution to journalArticle

Nerve Growth Factor Receptors
Ovary
Nerve Growth Factor
Nerve Growth Factor Receptor
Messenger RNA
54 Citations (Scopus)

The genes encoding nerve growth factor and its receptor are expressed in the developing female rat hypothalamus

Ojeda, S., Hill, D. F. & Katz, K. H., 1991, In : Molecular Brain Research. 9, 1-2, p. 47-55 9 p.

Research output: Contribution to journalArticle

Nerve Growth Factor Receptor
Nerve Growth Factor
Hypothalamus
Middle Hypothalamus
Preoptic Area
36 Citations (Scopus)

The mystery of mammalian puberty: How much more do we know?

Ojeda, S., 1991, In : Perspectives in Biology and Medicine. 34, 3, p. 365-383 19 p.

Research output: Contribution to journalArticle

gonadotropin-releasing hormone
puberty
hypothalamus
normal values
mammals
95 Citations (Scopus)

Transforming growth factor α contributes to the mechanism by which hypothalamic injury induces precocious puberty

Junier, M. P., Ma, Y. J., Costa, M. E., Hoffman, G., Hill, D. F. & Ojeda, S., 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 21, p. 9743-9747 5 p.

Research output: Contribution to journalArticle

Precocious Puberty
Transforming Growth Factors
Puberty
Wounds and Injuries
Anterior Hypothalamic Nucleus
1990
2 Citations (Scopus)

Editorial: Animal rights and the inertia of the scientific community

Ojeda, S., 1990, In : Endocrinology. 126, 2, p. 677-679 3 p.

Research output: Contribution to journalArticle

Animal Rights
Animal Welfare
Research
54 Citations (Scopus)

Epoxygenase products of arachidonic acid are endogenous constituents of the hypothalamus involved in D2 receptor-mediated, dopamine-induced release of somatostatin

Junier, M. P., Dray, F., Blair, I., Capdevila, J., Dishman, E., Falck, J. R. & Ojeda, S., Mar 1990, In : Endocrinology. 126, 3, p. 1534-1540 7 p.

Research output: Contribution to journalArticle

Median Eminence
Dopamine D2 Receptors
Somatostatin
Hypothalamus
Lipoxygenase
41 Citations (Scopus)

Expression of β-nerve growth factor in cultured cells derived from the hypothalamus and cerebral cortex

Gonzalez, D., Les Dees, W., Hiney, J. K., Ojeda, S. & Saneto, R. P., Mar 19 1990, In : Brain Research. 511, 2, p. 249-258 10 p.

Research output: Contribution to journalArticle

Nerve Growth Factor
Cerebral Cortex
Hypothalamus
Cultured Cells
Astrocytes
69 Citations (Scopus)

Guanethidine-mediated destruction of ovarian sympathetic nerves disrupts ovarian development and function in rats

Lara, H. E., McDonald, J. K., Ahmed, C. E. & Ojeda, S., Nov 1990, In : Endocrinology. 127, 5, p. 2199-2209 11 p.

Research output: Contribution to journalArticle

Guanethidine
Ovary
Neuropeptide Y
Gonadotropin-Releasing Hormone
Tyrosine 3-Monooxygenase
60 Citations (Scopus)

Hypothalamic aromatase activity in male and female rats during juvenile peripubertal development

Lephart, E. D. & Ojeda, S., 1990, In : Neuroendocrinology. 51, 4, p. 385-393 9 p.

Research output: Contribution to journalArticle

Aromatase
Puberty
Castration
Dihydrotestosterone
Oxidoreductases
122 Citations (Scopus)

Involvement of nerve growth factor in female sexual development

Lara, H. E., McDonald, J. K. & Ojeda, S., Jan 1990, In : Endocrinology. 126, 1, p. 364-375 12 p.

Research output: Contribution to journalArticle

Sexual Development
Nerve Growth Factor
Gonadotropin-Releasing Hormone
Neuropeptide Y
Ovary
150 Citations (Scopus)
Transforming Growth Factors
Gonadotropin-Releasing Hormone
Hypothalamus
Epidermal Growth Factor
Dinoprostone
78 Citations (Scopus)

The gene encoding nerve growth factor is expressed in the immature rat ovary: Effect of denervation and hormonal treatment

Lara, H. E., Hill, D. F., Katz, K. H. & Ojeda, S., Jan 1990, In : Endocrinology. 126, 1, p. 357-363 7 p.

Research output: Contribution to journalArticle

Nerve Growth Factor
Denervation
Ovary
Genes
Therapeutics
1989
27 Citations (Scopus)

Direct hypothalamic control of vasoactive intestinal peptide (VIP) levels in the developing rat ovary

Advis, J. P., Ahmed, C. E. & Ojeda, S., 1989, In : Brain Research Bulletin. 22, 4, p. 605-610 6 p.

Research output: Contribution to journalArticle

Vasoactive Intestinal Peptide
Ovary
Anterior Hypothalamic Nucleus
Cholesterol Side-Chain Cleavage Enzyme
Proestrus
21 Citations (Scopus)

Essential fatty acid deficiency delays the onset of puberty in the female rat

Smith, S. S., Neuringer, M. & Ojeda, S., 1989, In : Endocrinology. 125, 3, p. 1650-1659 10 p.

Research output: Contribution to journalArticle

Essential Fatty Acids
Puberty
Dinoprostone
Arachidonic Acid
Fatty Acids
26 Citations (Scopus)

Potential relevance of vasoactive intestinal peptide to ovarian physiology

Ojeda, S., Lara, H. & Ahmed, C. E., 1989, In : Seminars in Reproductive Endocrinology. 7, 1, p. 52-60 9 p.

Research output: Contribution to journalArticle

Vasoactive Intestinal Peptide
35 Citations (Scopus)

The role of arachidonic acid and its metabolites in the release of neuropeptides

Ojeda, S., Urbanski, H., Junier, M. P. & Capdevila, J., 1989, In : Annals of the New York Academy of Sciences. 559, p. 192-207 16 p.

Research output: Contribution to journalArticle

Arachidonic Acids
Somatostatin
Neuropeptides
Dinoprostone
Arachidonic Acid
22 Citations (Scopus)

The vaginal epithelium of immature rats metabolizes androgens through an aromatase-like reaction: changes during the time of puberty.

Lephart, E. D., Mathews, D., Noble, J. F. & Ojeda, S., Feb 1989, In : Biology of Reproduction. 40, 2, p. 259-267 9 p.

Research output: Contribution to journalArticle

Aromatase
Puberty
Androgens
Epithelium
Proestrus
1988
7 Citations (Scopus)
Median Eminence
Ketones
Phenylalanine
Gonadotropin-Releasing Hormone
Endopeptidases