Sergio Ojeda

Professor

  • 17488 Citations
  • 72 h-Index
1969 …2020

Research output per year

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Research Output

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Article
2001

Nerve growth factor is required for early follicular development in the mammalian ovary

Dissen, G. A., Romero, C., Hirshfield, A. N. & Ojeda, S. R., Jan 1 2001, In : Endocrinology. 142, 5, p. 2078-2086 9 p.

Research output: Contribution to journalArticle

Open Access
165 Scopus citations

TTF-1, a homeodomain gene required for diencephalic morphogenesis, is postnatally expressed in the neuroendocrine brain in a developmentally regulated and cell-specific fashion

Lee, B. J., Cho, G. J., Norgren, R. B., Junier, M. P., Hill, D. F., Tapia, V., Costa, M. E. & Ojeda, S. R., Jan 1 2001, In : Molecular and Cellular Neuroscience. 17, 1, p. 107-126 20 p.

Research output: Contribution to journalArticle

89 Scopus citations
2000

Alcohol ingestion inhibits the increased secretion of puberty-related hormones in the developing female rhesus monkey

Dees, W. L., Dissen, G. A., Hiney, J. K., Lara, F. & Ojeda, S. R., Jan 1 2000, In : Endocrinology. 141, 4, p. 1325-1331 7 p.

Research output: Contribution to journalArticle

Open Access
52 Scopus citations

An increased intraovarian synthesis of nerve growth factor and its low affinity receptor is a principal component of steroid-induced polycystic ovary in the rat

Lara, H. E., Dissen, G. A., Leyton, V., Paredes, A., Fuenzalida, H., Fiedler, J. L. & Ojeda, S. R., Jan 1 2000, In : Endocrinology. 141, 3, p. 1059-1072 14 p.

Research output: Contribution to journalArticle

Open Access
148 Scopus citations

Autocrine and paracrine Müllerian inhibiting substance hormone signaling in reproduction

Ingraham, H. A., Hirokawa, Y., Roberts, L. M., Mellon, S. H., McGee, E., Nachtigal, M. W., Visser, J. A., Schrader, W., Cidlowski, J., Ojeda, S., Cutler, G. & Kawashima, S., Dec 1 2000, In : Recent progress in hormone research. 55, p. 53-68 16 p.

Research output: Contribution to journalArticle

61 Scopus citations

D1-Receptor, DARPP-32, and PP-1 in the primate Corpus luteum and luteinized granulosa cells: Evidence for phosphorylation of DARPP-32 by dopamine and human chorionic gonadotropin

Mayerhofer, A., Fritz, S., Grünert, R., Sanders, S. L., Duffy, D. M., Ojeda, S. R. & Stouffer, R. L., Jan 1 2000, In : Journal of Clinical Endocrinology and Metabolism. 85, 12, p. 4750-4757 8 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Direct effects of nerve growth factor on thecal cells from antral ovarian follicles

Dissen, G. A., Parrott, J. A., Skinner, M. K., Hill, D. F., Costa, M. E. & Ojeda, S. R., Jan 1 2000, In : Endocrinology. 141, 12, p. 4736-4750 15 p.

Research output: Contribution to journalArticle

Open Access
79 Scopus citations

Glia-to-neuron signaling and the neuroendocrine control of female puberty

Ojeda, S. R., Ma, Y. J., Lee, B. J., Prevot, V., Veldhuis, J., Raff, S., Bremner, W., Kawashima, S. & Kochupillai, N., Dec 1 2000, In : Recent progress in hormone research. 55, p. 197-224 28 p.

Research output: Contribution to journalArticle

86 Scopus citations

Identification of an ovarian voltage-activated Na+-channel type: Hints to involvement in luteolysis

Bulling, A., Berg, F. D., Berg, U., Duffy, D. M., Stouffer, R. L., Ojeda, S. R., Gratzl, M. & Mayerhofer, A., Jan 1 2000, In : Molecular Endocrinology. 14, 7, p. 1064-1074 11 p.

Research output: Contribution to journalArticle

Open Access
42 Scopus citations

Intraovarian excess of nerve growth factor increases androgen secretion and disrupts estrous cyclicity in the rat

Dissen, G. A., Lara, H. E., Leyton, V., Paredes, A., Hill, D. F., Costa, M. E., Martinez-Serrano, A. & Ojeda, S. R., Jan 1 2000, In : Endocrinology. 141, 3, p. 1073-1082 10 p.

Research output: Contribution to journalArticle

Open Access
51 Scopus citations

Intrinsic neurons in the rat ovary: An immunohistochemical study

D'Albora, H., Lombide, P. & Ojeda, S. R., Apr 28 2000, In : Cell and tissue research. 300, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Neurotrophic and cell-cell dependent control of early follicular development

Ojeda, S. R., Romero, C., Tapia, V. & Dissen, G. A., May 25 2000, In : Molecular and Cellular Endocrinology. 163, 1-2, p. 67-71 5 p.

Research output: Contribution to journalArticle

90 Scopus citations
1999

Neuregulins signaling via a glial erbB-2-erbB-4 receptor complex contribute to the neuroendocrine control of mammalian sexual development

Ma, Y. J., Hill, D. F., Creswick, K. E., Costa, M. E., Cornea, A., Lioubin, M. N., Plowman, G. D. & Ojeda, S. R., Nov 15 1999, In : Journal of Neuroscience. 19, 22, p. 9913-9927 15 p.

Research output: Contribution to journalArticle

97 Scopus citations

Some hypothalamic hamartomas contain transforming growth factor α, a puberty-inducing growth factor, but not luteinizing hormone-releasing hormone neurons

Jung, H., Carmel, P., Schwartz, M. S., Witkin, J. W., Bentele, K. H. P., Westphal, M., Piatt, J. H., Costa, M. E., Cornea, A., Ma, Y. J. & Ojeda, S. R., Dec 1 1999, In : Journal of Clinical Endocrinology and Metabolism. 84, 12, p. 4695-4701 7 p.

Research output: Contribution to journalArticle

85 Scopus citations

The Oct-2 POU domain gene in the neuroendocrine brain: A transcriptional regulator of mammalian puberty

Ojeda, S. R., Hill, J., Hill, D. F., Costa, M. E., Tapia, V., Cornea, A. & Ma, Y. J., Jan 1 1999, In : Endocrinology. 140, 8, p. 3774-3789 16 p.

Research output: Contribution to journalArticle

Open Access
74 Scopus citations
1998

Epidermal growth factor tyrosine kinase receptors and the neuroendocrine control of mammalian puberty

Ojeda, S. R. & Ma, Y. J., May 25 1998, In : Molecular and Cellular Endocrinology. 140, 1-2, p. 101-106 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Oocytes are a source of catecholamines in the primate ovary: Evidence for a cell-cell regulatory loop

Mayerhofer, A., Smith, G. D., Danilchik, M., Levine, J. E., Wolf, D. P., Dissen, G. A. & Ojeda, S. R., Sep 1 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 18, p. 10990-10995 6 p.

Research output: Contribution to journalArticle

75 Scopus citations

Several GABA(A) receptor subunits are expressed in LHRH neurons of juvenile female rats

Jung, H., Shannon, E. M., Fritschy, J. M. & Ojeda, S. R., Jan 12 1998, In : Brain research. 780, 2, p. 218-229 12 p.

Research output: Contribution to journalArticle

81 Scopus citations
1997

A role for neurotransmitters in early follicular development: Induction of functional follicle-stimulating hormone receptors in newly formed follicles of the rat ovary

Mayerhofer, A., Dissen, G. A., Costa, M. E. & Ojeda, S. R., Jan 1 1997, In : Endocrinology. 138, 8, p. 3320-3329 10 p.

Research output: Contribution to journalArticle

Open Access
138 Scopus citations
107 Scopus citations

Expression of platelet-activating factor receptor in the hamster oviduct: Localization to the endosalpinx

Velasquez, L. A., Ojeda, S. R. & Croxatto, H. B., Jan 1 1997, In : Journal of Reproduction and Fertility. 109, 2, p. 349-354 6 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Hypothalamic astrocytes respond to transforming growth factor-α with the secretion of neuroactive substances that stimulate the release of luteinizing hormone-releasing hormone

Ma, Y. J., Berg-Von Der Emde, K., Rage, F., Wetsel, W. C. & Ojeda, S. R., Jan 1 1997, In : Endocrinology. 138, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

Open Access
123 Scopus citations

Neuroendocrine control of female puberty: Glial and neuronal interactions

Ma, Y. J. & Ojeda, S. R., Jan 1 1997, In : Journal of Investigative Dermatology Symposium Proceedings. 2, 1, p. 19-22 4 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Repression of gonadotropin-releasing hormone promoter activity by the POU homeodomain transcription factor SCIP/Oct-6/Tst-1: A regulatory mechanism of phenotype expression?

Wierman, M. E., Xiong, X., Kepa, J. K., Spaulding, A. J., Jacobsen, B. M., Fang, Z., Nilaver, G. & Ojeda, S. R., Mar 1997, In : Molecular and Cellular Biology. 17, 3, p. 1652-1665 14 p.

Research output: Contribution to journalArticle

Open Access
43 Scopus citations

Targeting transforming growth factor a expression to discrete loci of the neuroendocrine brain induces female sexual precocity

Rage, F., Hill, D. F., Sena-Esteves, M., Breakefield, X. O., Coffey, R. J., Costa, M. E., McCann, S. M. & Ojeda, S. R., Mar 18 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 6, p. 2735-2740 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

The transforming growth factor alpha gene family is involved in the neuroendocrine control of mammalian puberty

Ojeda, S. R., Ma, Y. J. & Rage, F., Jan 1 1997, In : Molecular Psychiatry. 2, 5, p. 355-358 4 p.

Research output: Contribution to journalArticle

Open Access
19 Scopus citations
1996

A role for TrkA nerve growth factor receptors in mammalian ovulation

Dissen, G. A., Hill, D. F., Costa, M. E., Les Dees, W., Lara, H. E. & Ojeda, S. R., Jan 1 1996, In : Endocrinology. 137, 1, p. 198-209 12 p.

Research output: Contribution to journalArticle

Open Access
122 Scopus citations

Basic fibroblast growth factor regulates the conversion of Pro-luteinizing hormone-releasing hormone (Pro-LHRH) to LHRH in immortalized hypothalamic neurons

Wetsel, W. C., Hill, D. F. & Ojeda, S. R., Jan 1 1996, In : Endocrinology. 137, 6, p. 2606-2616 11 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Insulin-like growth factor I of peripheral origin acts centrally to accelerate the initiation of female puberty

Hiney, J. K., Srivastava, V., Nyberg, C. L., Ojeda, S. R. & Dees, W. L., Jan 1 1996, In : Endocrinology. 137, 9, p. 3717-3728 12 p.

Research output: Contribution to journalArticle

Open Access
242 Scopus citations

Involvement of nerve growth factor in the ovulatory cascade: trkA receptor activation inhibits gap junctional communication between thecal cells

Mayerhofer, A., Dissen, G. A., Parrott, J. A., Hill, D. F., Mayerhofer, D., Garfield, R. E., Costa, M. E., Skinner, M. K. & Ojeda, S. R., Jan 1 1996, In : Endocrinology. 137, 12, p. 5662-5670 9 p.

Research output: Contribution to journalArticle

Open Access
70 Scopus citations

Neural and glial-mediated effects of growth factors acting via tyrosine kinase receptors on luteinizing hormone-releasing hormone neurons

Voigt, P., Ma, Y. J., Gonzalez, D., Fahrenbach, W. H., Wetsel, W. C., Berg-Von Der Emde, K., Hill, D. F., Taylor, K. G., Costa, M. E., Seidah, N. G. & Ojeda, S. R., Jan 1 1996, In : Endocrinology. 137, 6, p. 2593-2605 13 p.

Research output: Contribution to journalArticle

Open Access
65 Scopus citations

Participation of nerve growth factor in the regulation of ovarian function

Dissen, G. A., Mayerhofer, A. & Ojeda, S. R., Nov 1996, In : Zygote. 4, 4, p. 309-312 4 p.

Research output: Contribution to journalArticle

16 Scopus citations

RNase protection assay

Ma, Y. J., Dissen, G. A., Rage, F. & Ojeda, S. R., Dec 1996, In : Methods: A Companion to Methods in Enzymology. 10, 3, p. 273-278 6 p.

Research output: Contribution to journalArticle

36 Scopus citations

Testis of prepubertal rhesus monkeys receives a dual catecholaminergic input provided by the extrinsic innervation and an intragonadal source of catecholamines

Mayerhofer, A., Danilchik, M., Pau, K. Y. F., Lara, H. E., Russell, L. D. & Ojeda, S. R., Sep 1996, In : Biology of reproduction. 55, 3, p. 509-518 10 p.

Research output: Contribution to journalArticle

Open Access
34 Scopus citations
1995

Expression of neurotrophins and their receptors in the mammalian ovary is developmentally regulated: Changes at the time of folliculogenesis

Dissen, G. A., Newman Hirshfield, A., Malamed, S. & Ojeda, S. R., Oct 1995, In : Endocrinology. 136, 10, p. 4681-4692 12 p.

Research output: Contribution to journalArticle

134 Scopus citations

Neurotrophins and the neuroendocrine brain: Different neurotrophins sustain anatomically and functionally segregated subsets of hypothalamic dopaminergic neurons

Berg-Von der Emde, K., Dees, W. L., Hiney, J. K., Hill, D. F., Dissen, G. A., Costa, M. E., Moholt-Siebert, M. & Ojeda, S. R., Jan 1 1995, In : Journal of Neuroscience. 15, 6, p. 4223-4237 15 p.

Research output: Contribution to journalArticle

68 Scopus citations

The primate ovary contains a population of catecholaminergic neuron-like cells expressing nerve growth factor receptors

Dees, W. L., Hiney, J. K., Schultea, T. D., Mayerhofer, A., Danilchik, M., Dissen, G. A. & Ojeda, S. R., Apr 1995, In : Endocrinology. 136, 12, p. 5760-5768 9 p.

Research output: Contribution to journalArticle

65 Scopus citations
1994

Androgens regulate aromatase cytochrome P450 messenger ribonucleic acid in rat brain

Abdelgadir, S. E., Resko, J. A., Ojeda, S. R., Lephart, E. D., Mcphaul, M. J. & Roselli, C. E., Jul 1994, In : Endocrinology. 135, 1, p. 395-401 7 p.

Research output: Contribution to journalArticle

171 Scopus citations

Developmental expression of the genes encoding transforming growth factor alpha and its receptor in the hypothalamus of female rhesus macaques

Ma, Y. J., Costa, M. E. & Ojeda, S. R., Jan 1 1994, In : Neuroendocrinology. 60, 4, p. 346-359 14 p.

Research output: Contribution to journalArticle

95 Scopus citations

Developmental regulation of the ovary via growth factor tyrosine kinase receptors

Ojeda, S. R. & Dissen, G. A., Oct 1994, In : Trends in Endocrinology and Metabolism. 5, 8, p. 317-323 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression of epidermal growth factor receptor changes in the hypothalamus during the onset of female puberty

Ma, Y. J., Hill, D. F., Junier, M. P., Costa, M. E., Felder, S. E. & Ojeda, S. R., Jun 1994, In : Molecular and Cellular Neurosciences. 5, 3, p. 246-262 17 p.

Research output: Contribution to journalArticle

87 Scopus citations

Immature rat ovaries become revascularized rapidly after autotransplantation and show a gonadotropin-dependent increase in angiogenic factor gene expression

Dissen, G., Lara, H. E., Fahrenbach, W. H., Costa, M. E. & Ojeda, S., 1994, In : Endocrinology. 134, 3, p. 1146-1154 9 p.

Research output: Contribution to journalArticle

186 Scopus citations

Overexpression of a human transforming growth factor-alpha (TGF alpha) transgene reveals a dual antagonistic role of TGF alpha in female sexual development

Jun Ma, Y., Dissen, G., Merlino, G., Coquelin, A. & Ojeda, S., 1994, In : Endocrinology. 135, 4, p. 1392-1400 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

Region-specific regulation of transforming growth factor α (TGFα) gene expression in astrocytes of the neuroendocrine brain

Ma, Y. J., Berg-Von Der Emde, K., Moholt-Siebert, M., Hill, D. F. & Ojeda, S. R., Sep 1 1994, In : Journal of Neuroscience. 14, 9, p. 5644-5651 8 p.

Research output: Contribution to journalArticle

91 Scopus citations
1993

Activation of ovarian sympathetic nerves in polycystic ovary syndrome

Lara, H. E., Ferruz, J. L., Bustamante, D. A., Borges, Y. & Ojeda, S. R., Dec 1993, In : Endocrinology. 133, 6, p. 2690-2695 6 p.

Research output: Contribution to journalArticle

170 Scopus citations

Estradiol increases neural-specific class II-β-tubulin mRNA levels in the developing female hypothalamus by regulating mRNA stability

Rogers, L. C., De Boer, I., Junier, M. P. & Ojeda, S. R., Apr 1 1993, In : Molecular and Cellular Neuroscience. 4, 5, p. 424-431 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
63 Scopus citations

Ovarian steroidal response to gonadotropins and β-Adrenergic stimulation is enhanced in polycystic ovary syndrome: Role of sympathetic innervation

Barria, A., Leyton, V., Ojeda, S. R. & Lara, H. E., Dec 1993, In : Endocrinology. 133, 6, p. 2696-2703 8 p.

Research output: Contribution to journalArticle

129 Scopus citations
1992

Brain aromatase cytochrome P-450 messenger RNA levels and enzyme activity during prenatal and perinatal development in the rat

Lephart, E. D., Simpson, E. R., McPhaul, M. J., Kilgore, M. W., Wilson, J. D. & Ojeda, S. R., Dec 1992, In : Molecular Brain Research. 16, 3-4, p. 187-192 6 p.

Research output: Contribution to journalArticle

107 Scopus citations

Detection of Nerve Growth Factor and One of Its Receptors

Hill, D. F., Dissen, G., Ma, Y. J. & Ojeda, S., Jan 1 1992, In : Methods in Neurosciences. 9, C, p. 179-196 18 p.

Research output: Contribution to journalArticle

21 Scopus citations