Sergio Ojeda

Professor

  • 17308 Citations
  • 72 h-Index
1969 …2020
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Research Output 1969 2019

  • 17308 Citations
  • 72 h-Index
  • 335 Article
  • 6 Chapter
  • 1 Conference contribution
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Article
2004
54 Citations (Scopus)

Vascular endothelial cells promote acute plasticity in ependymoglial cells of the neuroendocrine brain

De Seranno, S., Estrella, C., Loyens, A., Cornea, A., Ojeda, S., Beauvillain, J. C. & Prevot, V., Nov 17 2004, In : Journal of Neuroscience. 24, 46, p. 10353-10363 11 p.

Research output: Contribution to journalArticle

Ependymoglial Cells
Endothelial Cells
Neuroglia
Brain
Median Eminence
2003
93 Citations (Scopus)

Activation of erbB-1 Signaling in Tanycytes of the Median Eminence Stimulates Transforming Growth Factor β1 Release via Prostaglandin E2 Production and Induces Cell Plasticity

Prevot, V., Cornea, A., Mungenast, A., Smiley, G. & Ojeda, S., Nov 19 2003, In : Journal of Neuroscience. 23, 33, p. 10622-10632 11 p.

Research output: Contribution to journalArticle

Ependymoglial Cells
Median Eminence
Transforming Growth Factors
Dinoprostone
Gonadotropin-Releasing Hormone
75 Citations (Scopus)

Glia-to-neuron signaling and the neuroendocrine control of female puberty

Ojeda, S., Prevot, V., Heger, S., Lomniczi, A., Dziedzic, B. & Mungenast, A., 2003, In : Annals of Medicine. 35, 4, p. 244-255 12 p.

Research output: Contribution to journalArticle

Puberty
Neuroglia
Neurons
Gonadotropin-Releasing Hormone
Excitatory Amino Acids
69 Citations (Scopus)

Neuron-to-glia signaling mediated by excitatory amino acid receptors regulates ErbB receptor function in astroglial cells of the neuroendocrine brain

Dziedzic, B., Prevot, V., Lomniczi, A., Jung, H., Cornea, A. & Ojeda, S., Feb 1 2003, In : Journal of Neuroscience. 23, 3, p. 915-926 12 p.

Research output: Contribution to journalArticle

Neuroendocrine Cells
Glutamate Receptors
Neuroglia
erbB Genes
Neurons
127 Citations (Scopus)

Normal female sexual development requires neuregulin-erbB receptor signaling in hypothalamic astrocytes

Prevot, V., Rio, C., Cho, G. J., Lomniczi, A., Heger, S., Neville, C. M., Rosenthal, N. A., Ojeda, S. & Corfas, G., Jan 1 2003, In : Journal of Neuroscience. 23, 1, p. 230-239 10 p.

Research output: Contribution to journalArticle

Neuregulins
Sexual Development
Gonadotropin-Releasing Hormone
Astrocytes
Neurons
42 Citations (Scopus)

Overexpression of glutamic acid decarboxylase-67 (GAD-67) in gonadotropin-releasing hormone neurons disrupts migratory fate and female reproductive function in mice

Heger, S., Seney, M., Bless, E., Schwarting, G. A., Bilger, M., Mungenast, A., Ojeda, S. & Tobet, S. A., Jun 1 2003, In : Endocrinology. 144, 6, p. 2566-2579 14 p.

Research output: Contribution to journalArticle

Glutamate Decarboxylase
Gonadotropin-Releasing Hormone
Neurons
gamma-Aminobutyric Acid
Genetically Modified Animals
14 Citations (Scopus)

The neurobiology of female puberty

Ojeda, S., Prevot, V., Heger, S., Lomniczi, A., Dziedzic, B. & Mungenast, A., 2003, In : Hormone Research. 60, SUPPL. 3, p. 15-20 6 p.

Research output: Contribution to journalArticle

Neurobiology
Puberty
Neuroglia
Neurons
Excitatory Amino Acids
27 Citations (Scopus)

TTF-1, a homeodomain-containing transcription factor, participates in the control of body fluid homeostasis by regulating angiotensinogen gene transcription in the rat subfornical organ

Son, Y. J., Hur, M. K., Ryu, B. J., Park, S. K., Damante, G., D'Elia, A. V., Costa, M. E., Ojeda, S. & Lee, B. J., Jul 18 2003, In : Journal of Biological Chemistry. 278, 29, p. 27043-27052 10 p.

Research output: Contribution to journalArticle

Subfornical Organ
Angiotensinogen
Body fluids
Body Fluids
Transcription
2002
210 Citations (Scopus)

Activation of A-type γ-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons

DeFazio, R. A., Heger, S., Ojeda, S. & Moenter, S. M., Dec 1 2002, In : Molecular Endocrinology. 16, 12, p. 2872-2891 20 p.

Research output: Contribution to journalArticle

LHRH Receptors
Aminobutyrates
Gonadotropin-Releasing Hormone
Neurons
GABA-A Receptors
36 Citations (Scopus)

Ca2+-activated, large conductance K+ channel in the ovary: Identification, characterization, and functional involvement in steroidogenesis

Kunz, L., Thalhammer, A., Berg, F. D., Berg, U., Duffy, D. M., Stouffer, R., Dissen, G., Ojeda, S. & Mayerhofer, A., Dec 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 12, p. 5566-5574 9 p.

Research output: Contribution to journalArticle

Granulosa Cells
Chorionic Gonadotropin
Ovary
Progesterone
Oxytocin
24 Citations (Scopus)

Intrinsic neurons in the mammalian ovary

D'Albora, H., Anesetti, G., Lombide, P., Les Dees, W. & Ojeda, S., Dec 15 2002, In : Microscopy Research and Technique. 59, 6, p. 484-489 6 p.

Research output: Contribution to journalArticle

ovaries
neurons
Neurons
Ovary
ovarian development
85 Citations (Scopus)

Nerve growth factor induces the expression of functional FSH receptors in newly formed follicles of the rat ovary

Romero, C., Paredes, A., Dissen, G. & Ojeda, S., 2002, In : Endocrinology. 143, 4, p. 1485-1494 10 p.

Research output: Contribution to journalArticle

FSH Receptors
Nerve Growth Factor
Ovary
Nerve Growth Factors
Gonadotropins
52 Citations (Scopus)

Neurotrophic control of ovarian development

Dissen, G., Romero, C., Paredes, A. & Ojeda, S., Dec 15 2002, In : Microscopy Research and Technique. 59, 6, p. 509-515 7 p.

Research output: Contribution to journalArticle

neurotrophins
ovarian development
Nerve Growth Factors
ovaries
endocrine systems
34 Citations (Scopus)

Pathogenesis of precocious puberty in hypothalamic hamartoma

Jung, H. & Ojeda, S., 2002, In : Hormone Research. 57, SUPPL. 2, p. 31-34 4 p.

Research output: Contribution to journalArticle

Precocious Puberty
Transforming Growth Factors
Gonadotropin-Releasing Hormone
Laughter
Nerve Tissue
2001
40 Citations (Scopus)

A conditional tetracycline-regulated increase in gamma amino butyric acid production near luteinizing hormone-releasing hormone nerve terminals disrupts estrous cyclicity in the rat

Bilger, M., Heger, S., Brann, D. W., Paredes, A. & Ojeda, S., 2001, In : Endocrinology. 142, 5, p. 2102-2114 13 p.

Research output: Contribution to journalArticle

Butyric Acid
Periodicity
Tetracycline
Gonadotropin-Releasing Hormone
Median Eminence
61 Citations (Scopus)

Expression of muscarinic receptor types in the primate ovary and evidence for nonneuronal acetylcholine synthesis

Fritz, S., Wessler, I., Breitling, R., Rossmanith, W., Ojeda, S., Dissen, G., Amsterdam, A. & Mayerhofer, A., 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 1, p. 349-354 6 p.

Research output: Contribution to journalArticle

Granulosa Cells
Muscarinic Receptors
Primates
Acetylcholine
Ovary
41 Citations (Scopus)

Intrinsic neurons in the human ovary

Anesetti, G., Lombide, P., D'Albora, H. & Ojeda, S., 2001, In : Cell and Tissue Research. 306, 2, p. 231-237 7 p.

Research output: Contribution to journalArticle

Neurons
Ovary
Nerve Growth Factor Receptors
Biosynthesis
Tyrosine 3-Monooxygenase
162 Citations (Scopus)

Nerve growth factor is required for early follicular development in the mammalian ovary

Dissen, G., Romero, C., Hirshfield, A. N. & Ojeda, S., 2001, In : Endocrinology. 142, 5, p. 2078-2086 9 p.

Research output: Contribution to journalArticle

Nerve Growth Factor
Ovary
Nerve Growth Factor Receptors
Peripheral Nervous System
Nerve Growth Factors
16 Citations (Scopus)

New thoughts on female precocious puberty

Ojeda, S. & Heger, S., 2001, In : Journal of Pediatric Endocrinology and Metabolism. 14, 3, p. 245-256 12 p.

Research output: Contribution to journalArticle

Precocious Puberty
Gonadotropin-Releasing Hormone
Puberty
Neurosecretory Systems
Excitatory Amino Acids
17 Citations (Scopus)

Regulation of puberty

Ojeda, S., Prevot, V. & Heger, S., 2001, In : Current Opinion in Endocrinology and Diabetes. 8, 3, p. 154-160 7 p.

Research output: Contribution to journalArticle

Puberty
Gonadotropin-Releasing Hormone
Neuroglia
Neurons
Excitatory Amino Acids
88 Citations (Scopus)

TTF-1, a homeodomain gene required for diencephalic morphogenesis, is postnatally expressed in the neuroendocrine brain in a developmentally regulated and cell-specific fashion

Lee, B. J., Cho, G. J., Norgren, R. B., Junier, M. P., Hill, D. F., Tapia, V., Costa, M. E. & Ojeda, S., 2001, In : Molecular and Cellular Neuroscience. 17, 1, p. 107-126 20 p.

Research output: Contribution to journalArticle

Morphogenesis
Puberty
Sexual Maturation
Sexual Development
Brain
2000
51 Citations (Scopus)

Alcohol ingestion inhibits the increased secretion of puberty-related hormones in the developing female rhesus monkey

Dees, W. L., Dissen, G., Hiney, J. K., Lara, F. & Ojeda, S., 2000, In : Endocrinology. 141, 4, p. 1325-1331 7 p.

Research output: Contribution to journalArticle

Puberty
Macaca mulatta
Eating
Alcohols
Hormones
147 Citations (Scopus)

An increased intraovarian synthesis of nerve growth factor and its low affinity receptor is a principal component of steroid-induced polycystic ovary in the rat

Lara, H. E., Dissen, G., Leyton, V., Paredes, A., Fuenzalida, H., Fiedler, J. L. & Ojeda, S., 2000, In : Endocrinology. 141, 3, p. 1059-1072 14 p.

Research output: Contribution to journalArticle

estradiol valerate
Nerve Growth Factor Receptor
Ovary
Steroids
Nerve Growth Factor
60 Citations (Scopus)

Autocrine and paracrine Müllerian inhibiting substance hormone signaling in reproduction

Ingraham, H. A., Hirokawa, Y., Roberts, L. M., Mellon, S. H., McGee, E., Nachtigal, M. W., Visser, J. A., Schrader, W., Cidlowski, J., Ojeda, S., Cutler, G. & Kawashima, S., 2000, In : Recent Progress in Hormone Research. 55, p. 53-68 16 p.

Research output: Contribution to journalArticle

Gonads
Reproduction
Cell Differentiation
Enzyme Repression
Cell Death
24 Citations (Scopus)
Dopamine D1 Receptors
Phosphorylation
Granulosa Cells
Phosphoproteins
Corpus Luteum
77 Citations (Scopus)

Direct effects of nerve growth factor on thecal cells from antral ovarian follicles

Dissen, G., Parrott, J. A., Skinner, M. K., Hill, D. F., Costa, M. E. & Ojeda, S., 2000, In : Endocrinology. 141, 12, p. 4736-4750 15 p.

Research output: Contribution to journalArticle

Ovarian Follicle
Nerve Growth Factor
Ovulation
trkA Receptor
Dinoprostone
86 Citations (Scopus)

Glia-to-neuron signaling and the neuroendocrine control of female puberty

Ojeda, S., Ma, Y. J., Lee, B. J., Prevot, V., Veldhuis, J., Raff, S., Bremner, W., Kawashima, S. & Kochupillai, N., 2000, In : Recent Progress in Hormone Research. 55, p. 197-224 28 p.

Research output: Contribution to journalArticle

Puberty
Gonadotropin-Releasing Hormone
Neuroglia
Neurons
Transforming Growth Factor alpha
41 Citations (Scopus)

Identification of an ovarian voltage-activated Na+-channel type: Hints to involvement in luteolysis

Bulling, A., Berg, F. D., Berg, U., Duffy, D. M., Stouffer, R., Ojeda, S., Gratzl, M. & Mayerhofer, A., 2000, In : Molecular Endocrinology. 14, 7, p. 1064-1074 11 p.

Research output: Contribution to journalArticle

Luteolysis
Granulosa Cells
Corpus Luteum
Tetrodotoxin
Veratridine
51 Citations (Scopus)

Intraovarian excess of nerve growth factor increases androgen secretion and disrupts estrous cyclicity in the rat

Dissen, G., Lara, H. E., Leyton, V., Paredes, A., Hill, D. F., Costa, M. E., Martinez-Serrano, A. & Ojeda, S., 2000, In : Endocrinology. 141, 3, p. 1073-1082 10 p.

Research output: Contribution to journalArticle

Nerve Growth Factor
Periodicity
Androgens
Ovary
estradiol valerate
41 Citations (Scopus)

Intrinsic neurons in the rat ovary: An immunohistochemical study

D'Albora, H., Lombide, P. & Ojeda, S., 2000, In : Cell and Tissue Research. 300, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

Neurons
Rats
Ovary
Primates
Neuropeptide Y
89 Citations (Scopus)

Neurotrophic and cell-cell dependent control of early follicular development

Ojeda, S., Romero, C., Tapia, V. & Dissen, G., May 25 2000, In : Molecular and Cellular Endocrinology. 163, 1-2, p. 67-71 5 p.

Research output: Contribution to journalArticle

Brain-Derived Neurotrophic Factor
Genes
Nerve Growth Factors
Nerve Growth Factor
trkB Receptor
1999
58 Citations (Scopus)

Glial-neuronal interactions in the neuroendocrine control of mammalian puberty: Facilitatory effects of gonadal steroids

Ojeda, S. & Ma, Y. J., Sep 15 1999, In : Journal of Neurobiology. 40, 4, p. 528-540 13 p.

Research output: Contribution to journalArticle

Puberty
Gonadotropin-Releasing Hormone
Neuroglia
Neuregulins
Steroids
97 Citations (Scopus)

Neuregulins signaling via a glial erbB-2-erbB-4 receptor complex contribute to the neuroendocrine control of mammalian sexual development

Ma, Y. J., Hill, D. F., Creswick, K. E., Costa, M. E., Cornea, A., Lioubin, M. N., Plowman, G. D. & Ojeda, S., Nov 15 1999, In : Journal of Neuroscience. 19, 22, p. 9913-9927 15 p.

Research output: Contribution to journalArticle

Neuregulins
Sexual Development
Neuroglia
Astrocytes
Oligodeoxyribonucleotides
85 Citations (Scopus)

Some hypothalamic hamartomas contain transforming growth factor α, a puberty-inducing growth factor, but not luteinizing hormone-releasing hormone neurons

Jung, H., Carmel, P., Schwartz, M. S., Witkin, J. W., Bentele, K. H. P., Westphal, M., Piatt, J. H., Costa, M. E., Cornea, A., Ma, Y. J. & Ojeda, S., 1999, In : Journal of Clinical Endocrinology and Metabolism. 84, 12, p. 4695-4701 7 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Puberty
Gonadotropin-Releasing Hormone
Neurons
Intercellular Signaling Peptides and Proteins
73 Citations (Scopus)

The Oct-2 POU domain gene in the neuroendocrine brain: A transcriptional regulator of mammalian puberty

Ojeda, S., Hill, J., Hill, D. F., Costa, M. E., Tapia, V., Cornea, A. & Ma, Y. J., 1999, In : Endocrinology. 140, 8, p. 3774-3789 16 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Puberty
Brain
Genes
Anterior Hypothalamus
1998
32 Citations (Scopus)

Epidermal growth factor tyrosine kinase receptors and the neuroendocrine control of mammalian puberty

Ojeda, S. & Ma, Y. J., May 25 1998, In : Molecular and Cellular Endocrinology. 140, 1-2, p. 101-106 6 p.

Research output: Contribution to journalArticle

Receptor Protein-Tyrosine Kinases
Puberty
Epidermal Growth Factor
Gonadotropin-Releasing Hormone
Neuregulins
Macaca mulatta
Catecholamines
Reproduction
Testis
75 Citations (Scopus)

Oocytes are a source of catecholamines in the primate ovary: Evidence for a cell-cell regulatory loop

Mayerhofer, A., Smith, G. D., Danilchik, M., Levine, J. E., Wolf, D. P., Dissen, G. & Ojeda, S., Sep 1 1998, In : Proceedings of the National Academy of Sciences of the United States of America. 95, 18, p. 10990-10995 6 p.

Research output: Contribution to journalArticle

Primates
Oocytes
Catecholamines
Ovary
Tyrosine 3-Monooxygenase
81 Citations (Scopus)

Several GABA(A) receptor subunits are expressed in LHRH neurons of juvenile female rats

Jung, H., Shannon, E. M., Fritschy, J. M. & Ojeda, S., Jan 12 1998, In : Brain Research. 780, 2, p. 218-229 12 p.

Research output: Contribution to journalArticle

GABA Receptors
Gonadotropin-Releasing Hormone
Neurons
gamma-Aminobutyric Acid
Confocal Microscopy
1997
138 Citations (Scopus)

A role for neurotransmitters in early follicular development: Induction of functional follicle-stimulating hormone receptors in newly formed follicles of the rat ovary

Mayerhofer, A., Dissen, G., Costa, M. E. & Ojeda, S., 1997, In : Endocrinology. 138, 8, p. 3320-3329 10 p.

Research output: Contribution to journalArticle

FSH Receptors
Vasoactive Intestinal Peptide
Neurotransmitter Agents
Ovary
Gonadotropins
107 Citations (Scopus)
Prostaglandin Receptors
Dinoprostone
Gonadotropin-Releasing Hormone
Neuroglia
Estradiol
12 Citations (Scopus)

Expression of platelet-activating factor receptor in the hamster oviduct: Localization to the endosalpinx

Velasquez, L. A., Ojeda, S. & Croxatto, H. B., 1997, In : Journal of Reproduction and Fertility. 109, 2, p. 349-354 6 p.

Research output: Contribution to journalArticle

Oviducts
Cricetinae
Platelet Activating Factor
Reverse Transcription
Embryonic Structures
122 Citations (Scopus)

Hypothalamic astrocytes respond to transforming growth factor-α with the secretion of neuroactive substances that stimulate the release of luteinizing hormone-releasing hormone

Ma, Y. J., Berg-Von Der Emde, K., Rage, F., Wetsel, W. C. & Ojeda, S., 1997, In : Endocrinology. 138, 1, p. 19-25 7 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Gonadotropin-Releasing Hormone
Astrocytes
Dinoprostone
Epidermal Growth Factor
12 Citations (Scopus)

Neuroendocrine control of female puberty: Glial and neuronal interactions

Ma, Y. J. & Ojeda, S., 1997, In : Journal of Investigative Dermatology Symposium Proceedings. 2, 1, p. 19-22 4 p.

Research output: Contribution to journalArticle

Puberty
Neuroglia
Gonadotropin-Releasing Hormone
Transforming Growth Factors
Neuregulin-1
43 Citations (Scopus)

Repression of gonadotropin-releasing hormone promoter activity by the POU homeodomain transcription factor SCIP/Oct-6/Tst-1: A regulatory mechanism of phenotype expression?

Wierman, M. E., Xiong, X., Kepa, J. K., Spaulding, A. J., Jacobsen, B. M., Fang, Z., Nilaver, G. & Ojeda, S., Mar 1997, In : Molecular and Cellular Biology. 17, 3, p. 1652-1665 14 p.

Research output: Contribution to journalArticle

Octamer Transcription Factor-6
Gonadotropin-Releasing Hormone
Phenotype
POU Domain Factors
Neurons
61 Citations (Scopus)

Targeting transforming growth factor α expression to discrete loci of the neuroendocrine brain induces female sexual precocity

Rage, F., Hill, D. F., Sena-Esteves, M., Breakefield, X. O., Coffey, R. J., Costa, M. E., McCann, S. M. & Ojeda, S., 1997, In : Proceedings of the National Academy of Sciences of the United States of America. 94, 6, p. 2735-2740 6 p.

Research output: Contribution to journalArticle

Transforming Growth Factors
Gonadotropin-Releasing Hormone
Precocious Puberty
Brain
Sexual Maturation
19 Citations (Scopus)

The transforming growth factor alpha gene family is involved in the neuroendocrine control of mammalian puberty

Ojeda, S., Ma, Y. J. & Rage, F., 1997, In : Molecular Psychiatry. 2, 5, p. 355-358 4 p.

Research output: Contribution to journalArticle

Transforming Growth Factor alpha
Puberty
Gonadotropin-Releasing Hormone
Neuroglia
Astrocytes
1996
120 Citations (Scopus)

A role for TrkA nerve growth factor receptors in mammalian ovulation

Dissen, G., Hill, D. F., Costa, M. E., Les Dees, W., Lara, H. E. & Ojeda, S., 1996, In : Endocrinology. 137, 1, p. 198-209 12 p.

Research output: Contribution to journalArticle

Nerve Growth Factor Receptors
Nerve Growth Factor
Ovulation
Messenger RNA
Neurotrophin 3
37 Citations (Scopus)

Basic fibroblast growth factor regulates the conversion of Pro-luteinizing hormone-releasing hormone (Pro-LHRH) to LHRH in immortalized hypothalamic neurons

Wetsel, W. C., Hill, D. F. & Ojeda, S., 1996, In : Endocrinology. 137, 6, p. 2606-2616 11 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Gonadotropin-Releasing Hormone
Neurons
Phorbol Esters
Protein Kinase C
241 Citations (Scopus)

Insulin-like growth factor I of peripheral origin acts centrally to accelerate the initiation of female puberty

Hiney, J. K., Srivastava, V., Nyberg, C. L., Ojeda, S. & Dees, W. L., 1996, In : Endocrinology. 137, 9, p. 3717-3728 12 p.

Research output: Contribution to journalArticle

Puberty
Insulin-Like Growth Factor I
Gonadotropin-Releasing Hormone
Median Eminence
IGF Type 1 Receptor