Sergio Ojeda

Professor

  • 17488 Citations
  • 72 h-Index
1969 …2020

Research output per year

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Research Output

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Article
2009

Nerve growth factor induces vascular endothelial growth factor expression in granulosa cells via a trkA receptor/mitogen-activated protein kinase-extracellularly regulated kinase 2-dependent pathway

Julio-Pieper, M., Lozada, P., Tapia, V., Vega, M., Miranda, C., Vantman, D., Ojeda, S. R. & Romero, C., Aug 2009, In : Journal of Clinical Endocrinology and Metabolism. 94, 8, p. 3065-3071 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

New concepts on the control of the onset of puberty

Ojeda, S., Lomniczi, A., Sandau, U. & Matagne, V., Nov 2009, In : Endocrine Development. 17, p. 44-51 8 p.

Research output: Contribution to journalArticle

NTRK1 and NTRK2 receptors facilitate follicle assembly and early follicular development in the mouse ovary

Kerr, B., Garcia-Rudaz, C., Dorfman, M., Paredes, A. & Ojeda, S. R., Jul 1 2009, In : Reproduction. 138, 1, p. 131-140 10 p.

Research output: Contribution to journalArticle

43 Scopus citations
2008

Fbxw15/Fbxo12J is an F-box protein-encoding gene selectively expressed in oocytes of the mouse ovary

De La Chesnaye, E., Kerr, B., Paredes, A., Merchant-Larios, H., Méndez, J. P. & Ojeda, S. R., Apr 1 2008, In : Biology of reproduction. 78, 4, p. 714-725 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Functional development of the ovarian noradrenergic innervation

Ricu, M., Paredes, A., Greiner, M., Ojeda, S. R. & Lara, H. E., Jan 1 2008, In : Endocrinology. 149, 1, p. 50-56 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Gene expression profiling of hypothalamic hamartomas: A search for genes associated with central precocious puberty

Parent, A. S., Matagne, V., Westphal, M., Heger, S., Ojeda, S. & Jung, H., Jan 1 2008, In : Hormone Research. 69, 2, p. 114-123 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Kinesin superfamily-associated protein 3 is preferentially expressed in glutamatergic neurons and contributes to the excitatory control of female puberty

Choi, J., Chang, M. H., Eun, J. C., Choon, S. J., Jeong, W. P., Baik, J. H., Park, J. Y., Costa, M. E., Ojeda, S. R. & Byung, J. L., Dec 1 2008, In : Endocrinology. 149, 12, p. 6146-6156 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

NELL2, a neuron-specific EGF-like protein, is selectively expressed in glutamatergic neurons and contributes to the glutamatergic control of GnRH neurons at puberty

Ha, C. M., Choi, J., Choi, E. J., Costa, M. E., Lee, B. J. & Ojeda, S. R., Oct 1 2008, In : Neuroendocrinology. 88, 3, p. 199-211 13 p.

Research output: Contribution to journalArticle

28 Scopus citations

Oxytocin facilitates female sexual maturation through a glia-to-neuron signaling pathway

Parent, A. S., Rasier, G., Matagne, V., Lomniczi, A., Lebrethon, M. C., Gérard, A., Ojeda, S. R. & Bourguignon, J. P., Mar 1 2008, In : Endocrinology. 149, 3, p. 1358-1365 8 p.

Research output: Contribution to journalArticle

32 Scopus citations
2007

A contactin-receptor-like protein tyrosine phosphatase β complex mediates adhesive communication between astroglial cells and gonadotrophin-releasing hormone neurones

Parent, A. S., Mungenast, A. E., Lomniczi, A., Sandau, U. S., Peles, E., Bosch, M. A., Rønnekleiv, O. K. & Ojeda, S. R., Nov 2007, In : Journal of Neuroendocrinology. 19, 11, p. 847-859 13 p.

Research output: Contribution to journalArticle

32 Scopus citations

Effects of alcohol on intraovarian nitric oxide synthase and steroidogenic acute regulatory protein in the prepubertal female rhesus monkey

Srivastava, V. K., Dissen, G. A., Ojeda, S. R., Hiney, J. K., Pine, M. D. & Les Dees, W., Mar 2007, In : Journal of Studies on Alcohol and Drugs. 68, 2, p. 182-191 10 p.

Research output: Contribution to journalArticle

7 Scopus citations

Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis

Heger, S., Mastronardi, C., Dissen, G. A., Lomniczi, A., Cabrera, R., Roth, C. L., Jung, H., Galimi, F., Sippell, W. & Ojeda, S. R., Aug 1 2007, In : Journal of Clinical Investigation. 117, 8, p. 2145-2154 10 p.

Research output: Contribution to journalArticle

71 Scopus citations

Evidence for circadian regulation of activating transcription factor 5 but not tyrosine hydroxylase by the chromaffin cell clock

Lemos, D. R., Goodspeed, L., Tonelli, L., Antoch, M. P., Ojeda, S. R. & Urbanski, H. F., Dec 1 2007, In : Endocrinology. 148, 12, p. 5811-5821 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression of a tumor-related gene network increases in the mammalian hypothalamus at the time of female puberty

Roth, C. L., Mastronardi, C., Lomniczi, A., Wright, H., Cabrera, R., Mungenast, A. E., Heger, S., Jung, H., Dubay, C. & Ojeda, S. R., Nov 1 2007, In : Endocrinology. 148, 11, p. 5147-5161 15 p.

Research output: Contribution to journalArticle

63 Scopus citations

Fxna, a novel gene differentially expressed in the rat ovary at the time of folliculogenesis, is required for normal ovarian histogenesis

Garcia-Rudaz, C., Luna, F., Tapia, V., Kerr, B., Colgin, L., Galimi, F., Dissen, G. A., Rawlings, N. D. & Ojeda, S. R., Mar 1 2007, In : Development. 134, 5, p. 945-957 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

FXYD1 is an MeCP2 target gene overexpressed in the brains of Rett syndrome patients and Mecp2-null mice

Deng, V., Matagne, V., Banine, F., Frerking, M., Ohliger, P., Budden, S., Pevsner, J., Dissen, G. A., Sherman, L. S. & Ojeda, S. R., Mar 15 2007, In : Human molecular genetics. 16, 6, p. 640-650 11 p.

Research output: Contribution to journalArticle

96 Scopus citations

Thyroid transcription factor-1 facilitates cerebrospinal fluid formation by regulating aquaporin-1 synthesis in the brain

Jae, G. K., Young, J. S., Chang, H. Y., Young, I. K., Il, S. N. G., Jun, H. P., Sang, K. P., Ojeda, S. R., D'Elia, A. V., Damante, G. & Byung, J. L., May 18 2007, In : Journal of Biological Chemistry. 282, 20, p. 14923-14931 9 p.

Research output: Contribution to journalArticle

34 Scopus citations
2006

Deletion of the Ttf1 gene in differentiated neurons disrupts female reproduction without impairing basal ganglia function

Mastronardi, C., Smiley, G. G., Raber, J., Kusakabe, T., Kawaguchi, A., Matagne, V., Dietzel, A., Heger, S., Mungenast, A. E., Cabrera, R., Kimura, S. & Ojeda, S. R., Dec 20 2006, In : Journal of Neuroscience. 26, 51, p. 13167-13179 13 p.

Research output: Contribution to journalArticle

52 Scopus citations

Expression of the insulin receptor-related receptor is induced by the preovulatory surge of luteinizing hormone in thecal-interstitial cells of the rat ovary

Dissen, G. A., Garcia-Rudaz, C., Tapia, V., Parada, L. F., Hsu, S. Y. T. & Ojeda, S. R., Jan 1 2006, In : Endocrinology. 147, 1, p. 155-165 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

FSH regulates acetycholine production by ovarian granulosa cells

Mayerhofer, A., Kunz, L., Krieger, A., Proskocil, B., Spindel, E., Amsterdam, A., Dissen, G. A., Ojeda, S. R. & Wessler, I., Jul 17 2006, In : Reproductive Biology and Endocrinology. 4, 37.

Research output: Contribution to journalArticle

25 Scopus citations
30 Scopus citations

Nerve growth factor-dependent activation of trkA receptors in the human ovary results in synthesis of follicle-stimulating hormone receptors and estrogen secretion

Salas, C., Julio-Pieper, M., Valladares, M., Pommer, R., Vega, M., Mastronardi, C., Kerr, B., Ojeda, S. R., Lara, H. E. & Romero, C., Jun 15 2006, In : Journal of Clinical Endocrinology and Metabolism. 91, 6, p. 2396-2403 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Neuroendocrine mechanisms controlling female puberty: New approaches, new concepts

Ojeda, S. R., Roth, C., Mungenast, A., Heger, S., Mastronardi, C., Parent, A. S., Lomniczi, A., Jung, H. & Høgberg, J., Feb 1 2006, In : International Journal of Andrology. 29, 1, p. 256-263 8 p.

Research output: Contribution to journalArticle

37 Scopus citations

Origin and ontogeny of mammalian ovarian neurons

Les Dees, W., Hiney, J. K., McArthur, N. H., Johnson, G. A., Dissen, G. A. & Ojeda, S. R., Jul 24 2006, In : Endocrinology. 147, 8, p. 3789-3796 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Pubertal development in Danish children: Comparison of recent European and US data

Juul, A., Teilmann, G., Scheike, T., Hertel, N. T., Holm, K., Laursen, E. M., Main, K. M., Skakkebæk, N. E., Hardy, K., Leridon, H., Aubert, M., Herman-Giddens, M. E. & Ojeda, S., Feb 1 2006, In : International Journal of Andrology. 29, 1, p. 247-255 9 p.

Research output: Contribution to journalArticle

186 Scopus citations

Quantitative proteomics identifies a change in glial glutamate metabolism at the time of female puberty

Roth, C. L., McCormack, A. L., Lomniczi, A., Mungenast, A. E. & Ojeda, S. R., Jul 25 2006, In : Molecular and Cellular Endocrinology. 254-255, p. 51-59 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Role of environmental factors in timing the onset and progression of puberty

De Muinck-Keizer Schrama, S., Juul, A., Anderson, R., Franks, S., Lyons, G., Ojeda, S. R., Aitken, R. J., Herman-Giddens, M. E., Biro, F., Schettler, T., Bourguignon, J. P., Von Eyben, F. E., Sippell, W. G. & Den Hond, E., Feb 1 2006, In : International Journal of Andrology. 29, 1, p. 286-290 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Voltage-dependent K+ channel acts as sex steroid sensor in endocrine cells of the human ovary

Kunz, L., Rämsch, R., Krieger, A., Young, K. A., Dissen, G. A., Stouffer, R. L., Ojeda, S. R. & Mayerhofer, A., Jan 1 2006, In : Journal of Cellular Physiology. 206, 1, p. 167-174 8 p.

Research output: Contribution to journalArticle

19 Scopus citations
2005

Early onset of puberty: Tracking genetic and environmental factors

Parent, A. S., Rasier, G., Gerard, A., Heger, S., Roth, C., Mastronardi, C., Jung, H., Ojeda, S. R. & Bourguignon, J. P., Nov 1 2005, In : Hormone Research. 64, SUPPL. 2, p. 41-47 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

erbB-1 and erbB-4 receptors act in concert to facilitate female sexual development and mature reproductive function

Prevot, V., Lomniczi, A., Corfas, G. & Ojeda, S. R., Mar 1 2005, In : Endocrinology. 146, 3, p. 1465-1472 8 p.

Research output: Contribution to journalArticle

59 Scopus citations

Expression of three gene families encoding cell-cell communication molecules in the prepubertal nonhuman primate hypothalamus

Mungenast, A. E. & Ojeda, S. R., Apr 1 2005, In : Journal of Neuroendocrinology. 17, 4, p. 208-219 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

Increased hypothalamic GPR54 signaling: A potential mechanism for initiation of puberty in primates

Shahab, M., Mastronardi, C., Seminara, S. B., Crowley, W. F., Ojeda, S. R. & Plant, T. M., Feb 8 2005, In : Proceedings of the National Academy of Sciences of the United States of America. 102, 6, p. 2129-2134 6 p.

Research output: Contribution to journalArticle

659 Scopus citations

Leveraging human genomic information to identify nonhuman primate sequences for expression array development

Spindel, E. R., Pauley, M. A., Jia, Y., Gravett, C., Thompson, S. L., Boyle, N. F., Ojeda, S. R. & Norgren, R. B., Nov 15 2005, In : BMC Genomics. 6, 160.

Research output: Contribution to journalArticle

23 Scopus citations

Loss of synaptonemal complex protein-1, a synaptonemal complex protein, contributes to the initiation of follicular assembly in the developing rat ovary

Paredes, A., Garcia-Rudaz, C., Kerr, B., Tapia, V., Dissen, G. A., Costa, M. E., Cornea, A. & Ojeda, S. R., Dec 1 2005, In : Endocrinology. 146, 12, p. 5267-5277 11 p.

Research output: Contribution to journalArticle

45 Scopus citations
2004

Alcohol alters luteinizing hormone secretion in immature female rhesus monkeys by a hypothalamic action

Dissen, G. A., Dearth, R. K., Scott, H. M., Ojeda, S. R. & Dees, W. L., Oct 1 2004, In : Endocrinology. 145, 10, p. 4558-4564 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

TrkB receptors are required for follicular growth and oocyte survival in the mammalian ovary

Paredes, A., Romero, C., Dissen, G. A., DeChiara, T. M., Reichardt, L., Cornea, A., Ojeda, S. R. & Xu, B., Mar 15 2004, In : Developmental Biology. 267, 2, p. 430-449 20 p.

Research output: Contribution to journalArticle

96 Scopus citations

Vascular endothelial cells promote acute plasticity in ependymoglial cells of the neuroendocrine brain

De Seranno, S., Estrella, C., Loyens, A., Cornea, A., Ojeda, S. R., Beauvillain, J. C. & Prevot, V., Nov 17 2004, In : Journal of Neuroscience. 24, 46, p. 10353-10363 11 p.

Research output: Contribution to journalArticle

56 Scopus citations
2003

Activation of erbB-1 Signaling in Tanycytes of the Median Eminence Stimulates Transforming Growth Factor β1 Release via Prostaglandin E2 Production and Induces Cell Plasticity

Prevot, V., Cornea, A., Mungenast, A., Smiley, G. & Ojeda, S. R., Nov 19 2003, In : Journal of Neuroscience. 23, 33, p. 10622-10632 11 p.

Research output: Contribution to journalArticle

96 Scopus citations

Neuron-to-glia signaling mediated by excitatory amino acid receptors regulates ErbB receptor function in astroglial cells of the neuroendocrine brain

Dziedzic, B., Prevot, V., Lomniczi, A., Jung, H., Cornea, A. & Ojeda, S. R., Feb 1 2003, In : Journal of Neuroscience. 23, 3, p. 915-926 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

Normal female sexual development requires neuregulin-erbB receptor signaling in hypothalamic astrocytes

Prevot, V., Rio, C., Cho, G. J., Lomniczi, A., Heger, S., Neville, C. M., Rosenthal, N. A., Ojeda, S. R. & Corfas, G., Jan 1 2003, In : Journal of Neuroscience. 23, 1, p. 230-239 10 p.

Research output: Contribution to journalArticle

Open Access
128 Scopus citations

Overexpression of glutamic acid decarboxylase-67 (GAD-67) in gonadotropin-releasing hormone neurons disrupts migratory fate and female reproductive function in mice

Heger, S., Seney, M., Bless, E., Schwarting, G. A., Bilger, M., Mungenast, A., Ojeda, S. R. & Tobet, S. A., Jun 1 2003, In : Endocrinology. 144, 6, p. 2566-2579 14 p.

Research output: Contribution to journalArticle

43 Scopus citations

The neurobiology of female puberty

Ojeda, S. R., Prevot, V., Heger, S., Lomniczi, A., Dziedzic, B. & Mungenast, A., Dec 30 2003, In : Hormone Research. 60, SUPPL. 3, p. 15-20 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

TTF-1, a homeodomain-containing transcription factor, participates in the control of body fluid homeostasis by regulating angiotensinogen gene transcription in the rat subfornical organ

Son, Y. J., Hur, M. K., Ryu, B. J., Park, S. K., Damante, G., D'Elia, A. V., Costa, M. E., Ojeda, S. R. & Lee, B. J., Jul 18 2003, In : Journal of Biological Chemistry. 278, 29, p. 27043-27052 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
2002

Activation of A-type γ-aminobutyric acid receptors excites gonadotropin-releasing hormone neurons

DeFazio, R. A., Heger, S., Ojeda, S. R. & Moenter, S. M., Dec 1 2002, In : Molecular Endocrinology. 16, 12, p. 2872-2891 20 p.

Research output: Contribution to journalArticle

216 Scopus citations

Ca2+-activated, large conductance K+ channel in the ovary: Identification, characterization, and functional involvement in steroidogenesis

Kunz, L., Thalhammer, A., Berg, F. D., Berg, U., Duffy, D. M., Stouffer, R. L., Dissen, G. A., Ojeda, S. R. & Mayerhofer, A., Dec 1 2002, In : Journal of Clinical Endocrinology and Metabolism. 87, 12, p. 5566-5574 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Nerve growth factor induces the expression of functional FSH receptors in newly formed follicles of the rat ovary

Romero, C., Paredes, A., Dissen, G. A. & Ojeda, S. R., Jan 1 2002, In : Endocrinology. 143, 4, p. 1485-1494 10 p.

Research output: Contribution to journalArticle

Open Access
86 Scopus citations

Pathogenesis of precocious puberty in hypothalamic hamartoma

Jung, H. & Ojeda, S. R., Jun 26 2002, In : Hormone Research. 57, SUPPL. 2, p. 31-34 4 p.

Research output: Contribution to journalArticle

35 Scopus citations
2001

A conditional tetracycline-regulated increase in gamma amino butyric acid production near luteinizing hormone-releasing hormone nerve terminals disrupts estrous cyclicity in the rat

Bilger, M., Heger, S., Brann, D. W., Paredes, A. & Ojeda, S. R., Jan 1 2001, In : Endocrinology. 142, 5, p. 2102-2114 13 p.

Research output: Contribution to journalArticle

Open Access
40 Scopus citations

Expression of muscarinic receptor types in the primate ovary and evidence for nonneuronal acetylcholine synthesis

Fritz, S., Wessler, I., Breitling, R., Rossmanith, W., Ojeda, S. R., Dissen, G. A., Amsterdam, A. & Mayerhofer, A., Feb 12 2001, In : Journal of Clinical Endocrinology and Metabolism. 86, 1, p. 349-354 6 p.

Research output: Contribution to journalArticle

61 Scopus citations

Intrinsic neurons in the human ovary

Anesetti, G., Lombide, P., D'Albora, H. & Ojeda, S. R., Oct 25 2001, In : Cell and tissue research. 306, 2, p. 231-237 7 p.

Research output: Contribution to journalArticle

41 Scopus citations