Sean Speese

Assistant Professor

Assistant Professor, Neurology

Emailspeese@ohsu.edu

1394 Citations
13 h-Index

If you made any changes in Pure, your changes will be visible here soon.

Fingerprint Dive into the research topics where Sean Speese is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

12 Similar Profiles

Drosophila Medicine & Life Sciences

Neuroglia Medicine & Life Sciences

Axons Medicine & Life Sciences

Synapses Medicine & Life Sciences

Lamin Type A Medicine & Life Sciences

Ribonucleoproteins Chemical Compounds

Lamins Medicine & Life Sciences

Wounds and Injuries Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2000 2017

1394 Citations
13 h-Index
17 Article

7 Citations (Scopus)

A novel Drosophila injury model reveals severed axons are cleared through a draper/MMP-1 signaling cascade

Purice, M. D., Ray, A., Münzel, E. J., Pope, B. J., Park, D. J., Speese, S. & Logan, M., Aug 21 2017, In : eLife. 6, e23611.

Research output: Contribution to journal › Article

Matrix Metalloproteinase 1

Neuroglia

Drosophila

Axons

Wounds and Injuries

14 Citations (Scopus)

Glial draper rescues Aβ toxicity in a Drosophila model of Alzheimer’s disease

Ray, A., Speese, S. & Logan, M., Dec 6 2017, In : Journal of Neuroscience. 37, 49, p. 11881-11893 13 p.

Research output: Contribution to journal › Article

Neuroglia

Drosophila

Alzheimer Disease

Diptera

Mitogen-Activated Protein Kinase 8

4 Citations (Scopus)

Protein phosphatase 4 coordinates glial membrane recruitment and phagocytic clearance of degenerating axons in Drosophila

Winfree, L. M., Speese, S. & Logan, M., Feb 23 2017, In : Cell death & disease. 8, 2, p. e2623

Research output: Contribution to journal › Article

Neuroglia

Drosophila

Axons

Membranes

Wounds and Injuries

15 Citations (Scopus)

Delayed glial clearance of degenerating axons in aged Drosophila is due to reduced PI3K/Draper activity

Purice, M. D., Speese, S. & Logan, M., Sep 20 2016, In : Nature Communications. 7, 12871.

Research output: Contribution to journal › Article

Drosophila

axons

1-Phosphatidylinositol 4-Kinase

clearances

Phosphatidylinositols

8 Citations (Scopus)

Insulin-like Signaling Promotes Glial Phagocytic Clearance of Degenerating Axons through Regulation of Draper

Musashe, D. T., Purice, M. D., Speese, S., Doherty, J. & Logan, M., Aug 16 2016, In : Cell Reports. 16, 7, p. 1838-1850 13 p.

Research output: Contribution to journal › Article

Neuroglia

Axons

Insulin

Insulin Receptor

Wounds and Injuries