• 2383 Citations
  • 27 h-Index
1978 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Research Output

  • 2383 Citations
  • 27 h-Index
  • 62 Article
  • 4 Review article
  • 3 Comment/debate
  • 2 Chapter

A cyclooxygenase-2 homologue encoded by rhesus cytomegalovirus is a determinant for endothelial cell tropism

Rue, C. A., Jarvis, M. A., Knoche, A. J., Meyers, H. L., DeFilippis, V. R., Hansen, S. G., Wagner, M., Früh, K., Anders, D. G., Wong, S. W., Barry, P. A. & Nelson, J. A., Nov 2004, In : Journal of virology. 78, 22, p. 12529-12536 8 p.

Research output: Contribution to journalArticle

38 Scopus citations
25 Scopus citations

Analysis of rhesus rhadinovirus microRNAs expressed in virus-induced tumors from infected rhesus macaques

Umbach, J. L., Strelow, L. I., Wong, S. W. & Cullen, B. R., Sep 30 2010, In : Virology. 405, 2, p. 592-599 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Anti-OX40 (CD134) administration to nonhuman primates: Immunostimulatory effects and toxicokinetic study

Weinberg, A. D., Thalhofer, C., Morris, N., Walker, J. M., Seiss, D., Wong, S., Axthelm, M. K., Picker, L. J. & Urba, W. J., Nov 1 2006, In : Journal of Immunotherapy. 29, 6, p. 575-585 11 p.

Research output: Contribution to journalArticle

42 Scopus citations

A rhesus macaque rhadinovirus related to Kaposi's sarcoma-associated herpesvirus/human herpesvirus 8 encodes a functional homologue of interleukin-6

Kaleeba, J. A. R., Bergquam, E. P. & Wong, S. W., Jun 23 1999, In : Journal of virology. 73, 7, p. 6177-6181 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

A rhesus rhadinovirus viral interferon (IFN) regulatory factor is virion associated and inhibits the early IFN antiviral response

Morin, G., Robinson, B. A., Rogers, K. S. & Wong, S. W., 2015, In : Journal of virology. 89, 15, p. 7707-7721 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

A simian hemorrhagic fever virus isolate from persistently infected baboons efficiently induces hemorrhagic fever disease in Japanese macaques

Vatter, H. A., Donaldson, E. F., Huynh, J., Rawlings, S., Manoharan, M., Legasse, A., Planer, S., Dickerson, M. F., Lewis, A. D., Colgin, L. M. A., Axthelm, M. K., Pecotte, J. K., Baric, R. S., Wong, S. W. & Brinton, M. A., Jan 1 2015, In : Virology. 474, p. 186-198 13 p.

Research output: Contribution to journalArticle

10 Scopus citations

A simian human immunodeficiency virus with a nonfunctional vpu (ΔvpuSHIVKU-1bMC33) isolated from a macaque with neuroAIDS has selected for mutations in env and nef that contributed to its pathogenic phenotype

Singh, D. K., McCormick, C., Pacyniak, E., Lawrence, K., Dalton, S. B., Pinson, D. M., Sun, F., Berman, N. E. J., Calvert, M., Gunderson, R. S., Wong, S. W. & Stephens, E. B., Mar 30 2001, In : Virology. 282, 1, p. 123-140 18 p.

Research output: Contribution to journalArticle

27 Scopus citations

Assessing genetic‐based therapies for AIDS using the simian immunodeficiency virus

Endres, C. L., Bergquam, E., Axthelm, M. K. & Wong, S. W., May 1995, In : Journal of medical primatology. 24, 3, p. 141-144 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

Author's correction: Viral interferon regulatory factors decrease the induction of type I and type II interferon during rhesus macaque rhadinovirus infection

Robinson, B. A., Estep, R. D., Messaoudi, I., Rogers, K. S. & Wong, S. W., Apr 1 2012, In : Journal of virology. 86, 8, 1 p.

Research output: Contribution to journalComment/debate

16 Scopus citations

BoHV-4-based vector single heterologous antigen delivery protects STAT1(-/-) mice from monkeypoxvirus lethal challenge

Franceschi, V., Parker, S., Jacca, S., Crump, R. W., Doronin, K., Hembrador, E., Pompilio, D., Tebaldi, G., Estep, R. D., Wong, S. W., Buller, M. R. & Donofrio, G., Jun 18 2015, In : PLoS neglected tropical diseases. 9, 6, e0003850.

Research output: Contribution to journalArticle

10 Scopus citations

Characterization of macaque pulmonary fluid proteome during monkeypox infection: Dynamics of host response

Brown, J. N., Estep, R. D., Lopez-Ferrer, D., Brewer, H. M., Clauss, T. R., Manes, N. P., O'Connor, M., Li, H., Adkins, J. N., Wong, S. W. & Smith, R. D., Dec 2010, In : Molecular and Cellular Proteomics. 9, 12, p. 2760-2771 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

Characterization of rhesus cytomegalovirus genes associated with anti- viral susceptibility

Swanson, R., Bergquam, E. & Wong, S. W., Jan 15 1998, In : Virology. 240, 2, p. 338-348 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Characterization of the complement inhibitory function of rhesus rhadinovirus complement control protein (RCP)

Okroj, M., Mark, L., Stokowska, A., Wong, S. W., Rose, N., Blackbourn, D. J., Villoutreix, B. O., Brad Spiller, O. & Blom, A. M., Jan 2 2009, In : Journal of Biological Chemistry. 284, 1, p. 505-514 10 p.

Research output: Contribution to journalArticle

20 Scopus citations

Comparative proteomics of human monkeypox and vaccinia intracellular mature and extracellular enveloped virions

Manes, N. P., Estep, R. D., Mottaz, H. M., Moore, R. J., Clauss, T. R. W., Monroe, M. E., Du, X., Adkins, J. N., Wong, S. W. & Smith, R. D., Mar 2008, In : Journal of Proteome Research. 7, 3, p. 960-968 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Complete sequence and genomic analysis of rhesus cytomegalovirus

Hansen, S. G., Strelow, L. I., Franchi, D. C., Anders, D. G. & Wong, S. W., Jun 1 2003, In : Journal of virology. 77, 12, p. 6620-6636 17 p.

Research output: Contribution to journalArticle

136 Scopus citations

Construction of an infectious rhesus rhadinovirus bacterial artificial chromosome for the analysis of Kaposi's sarcoma-associated herpesvirus-related disease development

Estep, R. D., Powers, M. F., Yen, B. K., Li, H. & Wong, S. W., Mar 1 2007, In : Journal of virology. 81, 6, p. 2957-2969 13 p.

Research output: Contribution to journalArticle

37 Scopus citations

Deletion of the monkeypox virus inhibitor of complement enzymes locus impacts the adaptive immune response to monkeypox virus in a nonhuman primate model of infection

Estep, R. D., Messaoudi, I., O'Connor, M. A., Li, H., Sprague, J., Barron, A., Engelmann, F., Yen, B., Powers, M. F., Jones, J. M., Robinson, B. A., Orzechowska, B. U., Manoharan, M., Legasse, A., Planer, S., Wilk, J., Axthelm, M. K. & Wong, S. W., Sep 1 2011, In : Journal of virology. 85, 18, p. 9527-9542 16 p.

Research output: Contribution to journalArticle

14 Scopus citations

Deletion of the vpu sequences prior to the env in a simian-human immunodeficiency virus results in enhanced Env precursor synthesis but is less pathogenic for pig-tailed macaques

Stephens, E. B., McCormick, C., Pacyniak, E., Griffin, D., Pinson, D. M., Sun, F., Nothnick, W., Wong, S. W., Gunderson, R., Berman, N. E. J. & Singh, D. K., Jan 1 2002, In : Virology. 293, 2, p. 252-261 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

DNA polymerases α and δ are immunologically and structurally distinct

Wong, S. W., Syvaoja, J., Tan, C. K., Downey, K. M., So, A. G., Linn, S. & Wang, T. S. F., Jan 1 1989, In : Journal of Biological Chemistry. 264, 10, p. 5924-5928 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Elements in the transcriptional regulatory region flanking herpes simplex virus type 1 oriS stimulate origin function

Wong, S. W. & Schaffer, P. A., Jan 1 1991, In : Journal of virology. 65, 5, p. 2601-2611 11 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

Erratum: Comparative proteomics of human monkeypox and vaccinia intracellular mature and extracellular enveloped virions (Journal of Proteome Research (2008) 7:3 (960-968) DOI: 10.1021/pr070432+)

Manes, N. P., Estep, R. D., Mottaz, H. M., Moore, R. J., Clauss, T. R. W., Monroe, M. E., Du, X., Adkins, J. N., Wong, S. W. & Smith, R. D., Jan 4 2013, In : Journal of Proteome Research. 12, 1, 1 p.

Research output: Contribution to journalComment/debate

Expression of the gibbon ape leukemia virus receptor-1 in rhesus macaque tissues

Wong, S. W., Swanson, R. M. & Bergquam, E. P., Jan 1 1997, In : Journal of medical primatology. 26, 1-2, p. 59-62 4 p.

Research output: Contribution to journalArticle

Fusion of the upstream vpu sequences to the env of simian human immunodeficiency virus (SHIVKU-1bMC33) results in the synthesis of two envelope precursor proteins, increased numbers of virus particles associated with the cell surface and is pathogenic for pig-tailed macaques

Hout, D. R., Gomez, M. L., Pacyniak, E., Mulcahy, E. R., Gomez, L. M., Jackson, M., Flick, M., Fegley, B., McCormick, C., Wisdom, B. J., Culley, N., Pinson, D. M., Powers, M., Wong, S. W. & Stephens, E. B., May 20 2004, In : Virology. 323, 1, p. 91-107 17 p.

Research output: Contribution to journalArticle

4 Scopus citations

Gammaherpesvirus infection and malignant disease in rhesus macaques experimentally infected with SIV or SHIV

Marshall, V. A., Labo, N., Hao, X. P., Holdridge, B., Thompson, M., Miley, W., Brands, C., Coalter, V., Kiser, R., Anver, M., Golubeva, Y., Warner, A., Jaffe, E. S., Piatak, M., Wong, S. W., Ohlen, C., MacAllister, R., Smedley, J., Deleage, C., Del Prete, G. Q. & 3 others, Lifson, J. D., Estes, J. D. & Whitby, D., Jul 2018, In : PLoS pathogens. 14, 7, e1007130.

Research output: Contribution to journalArticle

4 Scopus citations

Gene expression of human DNA polymerase α during cell proliferation and the cell cycle

Wahl, A. F., Geis, A. M., Spain, B. H., Wong, S. W., Korn, D. & Wang, T. S. F., Jan 1 1988, In : Molecular and cellular biology. 8, 11, p. 5016-5025 10 p.

Research output: Contribution to journalArticle

Open Access
99 Scopus citations

Generation of a life-expanded rhesus monkey fibroblast cell line for the growth of rhesus rhadinovirus (RRV)

Kirchoff, V., Wong, S., St.Jeor, S. & Pari, G. S., Mar 2 2002, In : Archives of Virology. 147, 2, p. 321-333 13 p.

Research output: Contribution to journalArticle

43 Scopus citations
10 Scopus citations

Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases.

Wong, S. W., Wahl, A. F., Yuan, P. M., Arai, N., Pearson, B. E., Arai, K., Korn, D., Hunkapiller, M. W. & Wang, T. S., Jan 1988, In : The EMBO journal. 7, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

294 Scopus citations

Human DNA polymerase α: Predicted functional domains and relationships with viral DNA polymerases

Wang, T. S. F., Wong, S. W. & Korn, D., Feb 21 1989, In : FASEB Journal. 3, 1, p. 14-21 8 p.

Research output: Contribution to journalReview article

157 Scopus citations

Identification of the rhesus macaque rhadinovirus lytic origin of DNA replication

Pari, G. S., Aucoin, D., Colletti, K., Cei, S. A., Kirchoff, V. & Wong, S. W., 2001, In : Journal of virology. 75, 23, p. 11401-11407 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Immune response to the West Nile virus in aged non- human primates

Wertheimer, A. M., Uhrlaub, J. L., Hirsch, A., Medigeshi, G., Sprague, J., Legasse, A., Wilk, J., Wiley, C. A., Didier, P., Tesh, R. B., Murray, K. O., Axthelm, M. K., Wong, S. W. & Nikolich-Žugich, J., Dec 15 2010, In : PloS one. 5, 12, e15514.

Research output: Contribution to journalArticle

16 Scopus citations

Immunopathology of Japanese macaque encephalomyelitis is similar to multiple sclerosis

Blair, T. C., Manoharan, M., Rawlings-Rhea, S. D., Tagge, I., Kohama, S. G., Hollister-Smith, J., Ferguson, B., Woltjer, R. L., Frederick, M. C., Pollaro, J., Rooney, W. D., Sherman, L. S., Bourdette, D. N. & Wong, S. W., Feb 15 2016, In : Journal of Neuroimmunology. 291, p. 1-10 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Induction of B cell hyperplasia in simian immunodeficiency virus- infected rhesus macaques with the simian homologue of Kaposi's sarcoma- associated herpesvirus

Wong, S. W., Bergquam, E. P., Swanson, R. M., Lee, F. W., Shiigi, S. M., Avery, N. A., Fanton, J. W. & Axthelm, M. K., Sep 20 1999, In : Journal of Experimental Medicine. 190, 6, p. 827-840 14 p.

Research output: Contribution to journalArticle

111 Scopus citations

Japanese macaque encephalomyelitis: A spontaneous multiple sclerosis-like disease in a nonhuman primate

Axthelm, M. K., Bourdette, D. N., Marracci, G. H., Su, W., Mullaney, E. T., Manoharan, M., Kohama, S. G., Pollaro, J., Witkowski, E., Wang, P., Rooney, W. D., Sherman, L. S. & Wong, S. W., Sep 1 2011, In : Annals of Neurology. 70, 3, p. 362-373 12 p.

Research output: Contribution to journalArticle

30 Scopus citations

Japanese macaque rhadinovirus encodes a viral microRNA mimic of the miR-17 family

Skalsky, R. L., Barr, S. A., Jeffery, A. J., Blair, T., Estep, R. & Wong, S. W., 2016, In : Journal of virology. 90, 20, p. 9350-9363 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Maternal or fetal origin of rhesus monkey (Macaca mulatta) amniotic fluid leukocytes can be identified by polymerase chain reaction using the zinc finger Y gene

Macias, A. E., Wong, S. W., Sadowsky, D. W., Luetjens, C. M., Axthelm, M. K., Gravett, M. G., Haluska, G. J. & Novy, M. J., Dec 3 2001, In : American Journal of Primatology. 55, 3, p. 159-170 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

Modulation of the severe CD4+ T-cell loss caused by a pathogenic simian-human immunodeficiency virus by replacement of the subtype B vpu with the vpu from a subtype C HIV-1 clinical isolate

Hill, M. S., Ruiz, A., Pacyniak, E., Pinson, D. M., Culley, N., Yen, B., Wong, S. W. & Stephens, E. B., Feb 5 2008, In : Virology. 371, 1, p. 86-97 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Molecular analysis of lymphoid tissue from rhesus macaque rhadinovirus-infected monkeys identifies alterations in host genes associated with oncogenesis

Estep, R. D., Govindan, A. N., Manoharan, M., Li, H., Fei, S. S., Park, B. S., Axthelm, M. K. & Wong, S. W., Jan 1 2020, In : PloS one. 15, 2, e0228484.

Research output: Contribution to journalArticle

Open Access

Molecular characterization of the Rhesus rhadinovirus (RRV) ORF4 gene and the RRV complement control protein it encodes

Mark, L., Spiller, O. B., Okroj, M., Chanas, S., Aitken, J. A., Wong, S. W., Damania, B., Blom, A. M. & Blackbourn, D. J., Apr 2007, In : Journal of virology. 81, 8, p. 4166-4176 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Monkeypox virus viral chemokine inhibitor (MPV vCCI), a potent inhibitor of rhesus macrophage inflammatory protein-1

Jones, J. M., Messauodi, I., Estep, R. D., Orzechowska, B. & Wong, S. W., Aug 1 2008, In : Cytokine. 43, 2, p. 220-228 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

Multiple diagnostic techniques identify previously vaccinated individuals with protective immunity against monkeypox

Hammarlund, E., Lewis, M. W., Carter, S. V., Amanna, I., Hansen, S. G., Strelow, L. I., Wong, S. W., Yoshihara, P., Hanifin, J. M. & Slifka, M. K., Sep 1 2005, In : Nature medicine. 11, 9, p. 1005-1011 7 p.

Research output: Contribution to journalArticle

75 Scopus citations

Mutations in the highly conserved SLQYLA motif of Vif in a simian-human immunodeficiency virus result in a less pathogenic virus and are associated with G-to-A mutations in the viral genome

Schmitt, K., Hill, M. S., Ruiz, A., Culley, N., Pinson, D. M., Wong, S. W. & Stephens, E. B., Jan 20 2009, In : Virology. 383, 2, p. 362-372 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

Neisseria infection of rhesus macaques as a model to study colonization, transmission, persistence, and horizontal gene transfer

Weyand, N. J., Wertheimer, A. M., Hobbs, T. R., Sisko, J. L., Taku, N. A., Gregston, L. D., Clary, S., Higashi, D. L., Biais, N., Brown, L. M., Planer, S. L., Legasse, A. W., Axthelm, M. K., Wong, S. W. & So, M., Feb 19 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 8, p. 3059-3064 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Nonhuman primate gamma-herpesviruses and their role in cancer

Estep, R. D. & Wong, S. W., Dec 13 2012, Cancer Associated Viruses. Robertson, E., Jasmin, J-F. & Lisanti, M. (eds.). p. 201-214 14 p. (Current Cancer Research; vol. 8).

Research output: Chapter in Book/Report/Conference proceedingChapter

Nonhuman primate models of human immunology

Messaoudi, I., Estep, R., Robinson, B. & Wong, S. W., Jan 15 2011, In : Antioxidants and Redox Signaling. 14, 2, p. 261-273 13 p.

Research output: Contribution to journalReview article

65 Scopus citations

Nonhuman primate models of human viral infections

Estes, J., Wong, S. & Brenchley, J. M., Mar 19 2018, (Accepted/In press) In : Nature Reviews Immunology. p. 1-15 15 p.

Research output: Contribution to journalArticle

20 Scopus citations

Optimization of proteomic sample preparation procedures for comprehensive protein characterization of pathogenic systems

Mottaz-Brewer, H. M., Norbeck, A. D., Adkins, J. N., Manes, N. P., Ansong, C., Shi, L., Rikihisa, Y., Kikuchi, T., Wong, S. W., Estep, R. D., Heffron, F., Pasa-Tolic, L. & Smith, R. D., Dec 1 2008, In : Journal of Biomolecular Techniques. 19, 5, p. 285-295 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Prevalence of viremia and oral shedding of rhesus rhadinovirus and retroperitoneal fibromatosis herpesvirus in large age-structured breeding groups of rhesus macaques (Macaca mulatta)

White, J. A., Todd, P. A., Yee, J. A. L., Kalman-Bowlus, A., Rodgers, K. S., Xiaowei, Y., Wong, S. W., Barry, P. & Lerche, N. W., Aug 1 2009, In : Comparative Medicine. 59, 4, p. 383-390 8 p.

Research output: Contribution to journalArticle

18 Scopus citations