Scott Hansen

Associate Professor

  • 3989 Citations
  • 22 h-Index
19992020

Research output per year

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Research Output

  • 3989 Citations
  • 22 h-Index
  • 39 Article
  • 4 Comment/debate
  • 2 Review article
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Article
1999

Analysis of the site occupancy constraints of primary amino acid sequences in the motif directing palmitylation of the vaccinia virus 37-kDa envelope protein

Hansen, S. G., Grosenbach, D. W. & Hruby, D. E., Feb 1 1999, In : Virology. 254, 1, p. 124-137 14 p.

Research output: Contribution to journalArticle

7 Scopus citations
2000

Identification and analysis of vaccinia virus palmitylproteins

Grosenbach, D. W., Hansen, S. G. & Hruby, D. E., Sep 15 2000, In : Virology. 275, 1, p. 193-206 14 p.

Research output: Contribution to journalArticle

31 Scopus citations

Interaction of GRASP, a protein encoded by a novel retinoic acid-induced gene, with members of the cytohesin family of guanine nucleotide exchange factors

Nevrivy, D. J., Peterson, V. J., Avram, D., Ishmael, J. E., Hansen, S. G., Dowell, P., Hruby, D. E., Dawson, M. I. & Leid, M., Jun 2 2000, In : Journal of Biological Chemistry. 275, 22, p. 16827-16836 10 p.

Research output: Contribution to journalArticle

67 Scopus citations
2002

BiZyme: A novel fusion protein-mediating selection of vaccinia virus recombinants by fluorescence and antibiotic resistance

Hansen, S. G., Cope, T. A. & Hruby, D. E., Jan 1 2002, In : BioTechniques. 32, 5, p. 1178-1187 10 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2003

Complete sequence and genomic analysis of rhesus cytomegalovirus

Hansen, S. G., Strelow, L. I., Franchi, D. C., Anders, D. G. & Wong, S. W., Jun 1 2003, In : Journal of virology. 77, 12, p. 6620-6636 17 p.

Research output: Contribution to journalArticle

136 Scopus citations

Duration of antiviral immunity after smallpox vaccination

Hammarlund, E., Lewis, M. W., Hansen, S. G., Strelow, L. I., Nelson, J. A., Sexton, G. J., Hanifin, J. M. & Slifka, M. K., Sep 1 2003, In : Nature medicine. 9, 9, p. 1131-1137 7 p.

Research output: Contribution to journalArticle

587 Scopus citations
2004

A cyclooxygenase-2 homologue encoded by rhesus cytomegalovirus is a determinant for endothelial cell tropism

Rue, C. A., Jarvis, M. A., Knoche, A. J., Meyers, H. L., DeFilippis, V. R., Hansen, S. G., Wagner, M., Früh, K., Anders, D. G., Wong, S. W., Barry, P. A. & Nelson, J. A., Nov 1 2004, In : Journal of virology. 78, 22, p. 12529-12536 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Kaposi sarcoma-associated herpesvirus (KSHV) induces heme oxygenase-1 expression and activity in KSHV-infected endothelial cells

McAllister, S. C., Hansen, S. G., Ruhl, R. A., Raggo, C. M., DeFilippis, V. R., Greenspan, D., Früh, K. & Moses, A. V., May 1 2004, In : Blood. 103, 9, p. 3465-3473 9 p.

Research output: Contribution to journalArticle

73 Scopus citations
2005

Increased efficiency of phorbol ester-induced lytic reactivation of Kaposi's sarcoma-associated herpesvirus during S phase

McAllister, S. C., Hansen, S. G., Messaoudi, I., Nikolich-Zugich, J. & Moses, A. V., Feb 1 2005, In : Journal of virology. 79, 4, p. 2626-2630 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Multiple diagnostic techniques identify previously vaccinated individuals with protective immunity against monkeypox

Hammarlund, E., Lewis, M. W., Carter, S. V., Amanna, I., Hansen, S. G., Strelow, L. I., Wong, S. W., Yoshihara, P., Hanifin, J. M. & Slifka, M. K., Sep 1 2005, In : Nature medicine. 11, 9, p. 1005-1011 7 p.

Research output: Contribution to journalArticle

75 Scopus citations
2006

IL-15 induces CD4+ effector memory T cell production and tissue emigration in nonhuman primates

Picker, L. J., Reed-Inderbitzin, E. F., Hagen, S. I., Edgar, J. B., Hansen, S. G., Legasse, A., Planer, S., Piatak, M., Lifson, J. D., Maino, V. C., Axthelm, M. K. & Villinger, F., Jun 1 2006, In : Journal of Clinical Investigation. 116, 6, p. 1514-1524 11 p.

Research output: Contribution to journalArticle

143 Scopus citations

Interferon regulatory factor 3 is necessary for induction of antiviral genes during human cytomegalovirus infection

DeFilippis, V. R., Robinson, B., Keck, T. M., Hansen, S. G., Nelson, J. A. & Früh, K. J., Jan 1 2006, In : Journal of virology. 80, 2, p. 1032-1037 6 p.

Research output: Contribution to journalArticle

50 Scopus citations
2009

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

Hansen, S. G., Vieville, C., Whizin, N., Coyne-Johnson, L., Siess, D. C., Drummond, D. D., Legasse, A. W., Axthelm, M. K., Oswald, K., Trubey, C. M., Piatak, M., Lifson, J. D., Nelson, J. A., Jarvis, M. A. & Picker, L. J., Mar 1 2009, In : Nature medicine. 15, 3, p. 293-299 7 p.

Research output: Contribution to journalArticle

514 Scopus citations
2010

Evasion of CD8+ T Cells Is Critical for Superinfection by Cytomegalovirus

Hansen, S. G., Powers, C. J., Richards, R., Ventura, A. B., Ford, J. C., Siess, D., Axthelm, M. K., Nelson, J. A., Jarvis, M. A., Picker, L. J. & Früh, K., Apr 2 2010, In : Science. 328, 5974, p. 102-106 5 p.

Research output: Contribution to journalArticle

175 Scopus citations
2011

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

Hansen, S. G., Ford, J. C., Lewis, M. S., Ventura, A. B., Hughes, C. M., Coyne-Johnson, L., Whizin, N., Oswald, K., Shoemaker, R., Swanson, T., Legasse, A. W., Chiuchiolo, M. J., Parks, C. L., Axthelm, M. K., Nelson, J. A., Jarvis, M. A., Piatak, M., Lifson, J. D. & Picker, L. J., May 26 2011, In : Nature. 473, 7348, p. 523-527 5 p.

Research output: Contribution to journalArticle

681 Scopus citations
2012

Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines

Fukazawa, Y., Park, H., Cameron, M. J., Lefebvre, F., Lum, R., Coombes, N., Mahyari, E., Hagen, S. I., Bae, J. Y., Reyes, M. D., Swanson, T., Legasse, A. W., Sylwester, A., Hansen, S. G., Smith, A. T., Stafova, P., Shoemaker, R., Li, Y., Oswald, K., Axthelm, M. K. & 8 others, McDermott, A., Ferrari, G., Montefiori, D. C., Edlefsen, P. T., Piatak, M., Lifson, J. D., Sékaly, R. P. & Picker, L. J., Nov 1 2012, In : Nature medicine. 18, 11, p. 1673-1681 9 p.

Research output: Contribution to journalArticle

104 Scopus citations
2013
10 Scopus citations

Immune clearance of highly pathogenic SIV infection

Hansen, S. G., Jr, M. P., Ventura, A. B., Hughes, C. M., Gilbride, R. M., Ford, J. C., Oswald, K., Shoemaker, R., Li, Y., Lewis, M. S., Gilliam, A. N., Xu, G., Whizin, N., Burwitz, B. J., Planer, S. L., Turner, J. M., Legasse, A. W., Axthelm, M. K., Nelson, J. A., Früh, K. & 6 others, Sacha, J. B., Estes, J. D., Keele, B. F., Edlefsen, P. T., Lifson, J. D. & Picker, L. J., Jan 1 2013, In : Nature. 502, 7469, p. 100-104 5 p.

Research output: Contribution to journalArticle

363 Scopus citations
2014

Cytomegalovirus pp65 limits dissemination but is dispensable for persistence

Malouli, D., Hansen, S. G., Nakayasu, E. S., Marshall, E. E., Hughes, C. M., Ventura, A. B., Gilbride, R. M., Lewis, M. S., Xu, G., Kreklywich, C., Whizin, N., Fischer, M., Legasse, A. W., Viswanathan, K., Siess, D., Camp, D. G., Axthelm, M. K., Kahl, C., DeFilippis, V. R., Smith, R. D. & 3 others, Streblow, D. N., Picker, L. J. & Früh, K., 2014, In : Journal of Clinical Investigation. 124, 5, p. 1928-1944 17 p.

Research output: Contribution to journalArticle

19 Scopus citations

Expansion of dysfunctional Tim-3 - Expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques

Fujita, T., Burwitz, B. J., Chew, G. M., Reed, J. S., Pathak, R., Seger, E., Clayton, K. L., Rini, J. M., Ostrowski, M. A., Ishii, N., Kuroda, M. J., Hansen, S. G., Sacha, J. B. & Ndhlovu, L. C., Dec 1 2014, In : Journal of Immunology. 193, 11, p. 5576-5583 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Full genome sequence analysis of a novel adenovirus of rhesus macaque origin indicates a new simian adenovirus type and species

Malouli, D., Howell, G. L., Legasse, A. W., Kahl, C., Axthelm, M. K., Hansen, S. G. & Früh, K., Sep 1 2014, In : Virology Reports. 3, p. 18-29 12 p.

Research output: Contribution to journalArticle

6 Scopus citations
2016

Broadly targeted CD8+ T cell responses restricted by major histocompatibility complex E

Hansen, S., Wu, H. L., Burwitz, B., Hughes, C. M., Hammond, K. B., Ventura, A. B., Reed, J. S., Gilbride, R. M., Ainslie, E., Morrow, D. W., Ford, J. C., Selseth, A. N., Pathak, R., Malouli, D., Legasse, A. W., Axthelm, M., Nelson, J., Gillespie, G. M., Walters, L. C., Brackenridge, S. & 8 others, Sharpe, H. R., López, C. A., Frueh, K., Korber, B. T., McMichael, A. J., Gnanakaran, S., Sacha, J. & Picker, L., Feb 12 2016, In : Science. 351, 6274, p. 714-720 7 p.

Research output: Contribution to journalArticle

142 Scopus citations

Cross-Species Rhesus Cytomegalovirus Infection of Cynomolgus Macaques

Burwitz, B., Malouli, D., Bimber, B. N., Reed, J. S., Ventura, A. B., Hancock, M., Uebelhoer, L. S., Bhusari, A., Hammond, K. B., Espinosa Trethewy, R. G., Klug, A., Legasse, A. W., Axthelm, M., Nelson, J., Park, B., Streblow, D., Hansen, S., Picker, L., Frueh, K. & Sacha, J., Nov 1 2016, In : PLoS Pathogens. 12, 11, e1006014.

Research output: Contribution to journalArticle

16 Scopus citations

Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus

Sturgill, E. R., Malouli, D., Hansen, S., Burwitz, B., Seo, S., Schneider, C. L., Womack, J. L., Verweij, M., Ventura, A. B., Bhusari, A., Jeffries, K. M., Legasse, A. W., Axthelm, M., Hudson, A. W., Sacha, J., Picker, L. & Frueh, K., Aug 1 2016, In : PLoS Pathogens. 12, 8, e1005868.

Research output: Contribution to journalArticle

17 Scopus citations

TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection

Chew, G. M., Fujita, T., Webb, G. M., Burwitz, B. J., Wu, H. L., Reed, J. S., Hammond, K. B., Clayton, K. L., Ishii, N., Abdel-Mohsen, M., Liegler, T., Mitchell, B. I., Hecht, F. M., Ostrowski, M., Shikuma, C. M., Hansen, S. G., Maurer, M., Korman, A. J., Deeks, S. G., Sacha, J. B. & 1 others, Ndhlovu, L. C., Jan 1 2016, In : PLoS pathogens. 12, 1, e1005349.

Research output: Contribution to journalArticle

104 Scopus citations
2017

MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates

Greene, J. M., Dash, P., Roy, S., McMurtrey, C., Awad, W., Reed, J. S., Hammond, K. B., Abdulhaqq, S., Wu, H. L., Burwitz, B., Roth, B. F., Morrow, D. W., Ford, J. C., Xu, G., Bae, J. Y., Crank, H., Legasse, A. W., Dang, T. H., Greenaway, H. Y., Kurniawan, M. & 14 others, Gold, M., Harriff, M., Lewinsohn, D., Park, B., Axthelm, M., Stanton, J., Hansen, S., Picker, L., Venturi, V., Hildebrand, W., Thomas, P. G., Lewinsohn, D., Adams, E. J. & Sacha, J., May 1 2017, In : Mucosal Immunology. 10, 3, p. 802-813 12 p.

Research output: Contribution to journalArticle

41 Scopus citations
2018

Early antiretroviral therapy limits SIV reservoir establishment to delay or prevent post-treatment viral rebound

Okoye, A. A., Hansen, S. G., Vaidya, M., Fukazawa, Y., Park, H., Duell, D. M., Lum, R., Hughes, C. M., Ventura, A. B., Ainslie, E., Ford, J. C., Morrow, D., Gilbride, R. M., Legasse, A. W., Hesselgesser, J., Geleziunas, R., Li, Y., Oswald, K., Shoemaker, R., Fast, R. & 6 others, Bosche, W. J., Borate, B. R., Edlefsen, P. T., Axthelm, M. K., Picker, L. J. & Lifson, J. D., Sep 1 2018, In : Nature medicine. 24, 9, p. 1430-1440 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding

Walters, L. C., Harlos, K., Brackenridge, S., Rozbesky, D., Barrett, J. R., Jain, V., Walter, T. S., O’Callaghan, C. A., Borrow, P., Toebes, M., Hansen, S., Sacha, J., Abdulhaqq, S., Greene, J. M., Frueh, K., Marshall, E., Picker, L., Jones, E. Y., McMichael, A. J. & Gillespie, G. M., Dec 1 2018, In : Nature Communications. 9, 1, 3137.

Research output: Contribution to journalArticle

15 Scopus citations

Prevention of tuberculosis in rhesus macaques by a cytomegalovirus-based vaccine

Hansen, S. G., Zak, D. E., Xu, G., Ford, J. C., Marshall, E. E., Malouli, D., Gilbride, R. M., Hughes, C. M., Ventura, A. B., Ainslie, E., Randall, K. T., Selseth, A. N., Rundstrom, P., Herlache, L., Lewis, M. S., Park, H., Planer, S. L., Turner, J. M., Fischer, M., Armstrong, C. & 20 others, Zweig, R. C., Valvo, J., Braun, J. M., Shankar, S., Lu, L., Sylwester, A. W., Legasse, A. W., Messerle, M., Jarvis, M. A., Amon, L. M., Aderem, A., Alter, G., Laddy, D. J., Stone, M., Bonavia, A., Evans, T. G., Axthelm, M. K., Früh, K., Edlefsen, P. T. & Picker, L. J., Feb 1 2018, In : Nature medicine. 24, 2, p. 130-143 14 p.

Research output: Contribution to journalArticle

74 Scopus citations

The Role of MHC-E in T Cell immunity is conserved among humans, rhesus macaques, and cynomolgus macaques

Wu, H. L., Wiseman, R. W., Hughes, C. M., Webb, G. M., Abdulhaqq, S. A., Bimber, B. N., Hammond, K. B., Reed, J. S., Gao, L., Burwitz, B. J., Greene, J. M., Ferrer, F., Legasse, A. W., Axthelm, M. K., Park, B. S., Brackenridge, S., Maness, N. J., McMichael, A. J., Picker, L. J., O'Connor, D. H. & 2 others, Hansen, S. G. & Sacha, J. B., Jan 1 2018, In : Journal of Immunology. 200, 1, p. 49-60 12 p.

Research output: Contribution to journalArticle

15 Scopus citations
2019

Acute infection and subsequent subclinical reactivation of herpes simplex virus 2 after vaginal inoculation of rhesus macaques

Lo, M., Zhu, J., Hansen, S. G., Carroll, T., Zuend, C. F., Nöel-Romas, L., Ma, Z. M., Fritts, L., Huang, M. L., Sun, S., Huang, Y., Koelle, D. M., Picker, L. J., Burgener, A., Corey, L. & Miller, C. J., Jan 1 2019, In : Journal of virology. 93, 2, e01574-18.

Research output: Contribution to journalArticle

2 Scopus citations

Characterization of a live-attenuated HCMV-based vaccine platform

Caposio, P., van den Worm, S., Crawford, L., Perez, W., Kreklywich, C., Gilbride, R. M., Hughes, C. M., Ventura, A. B., Ratts, R., Marshall, E. E., Malouli, D., Axthelm, M. K., Streblow, D., Nelson, J. A., Picker, L. J., Hansen, S. G. & Früh, K., Dec 1 2019, In : Scientific Reports. 9, 1, 19236.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Cytomegalovirus vectors expressing Plasmodium knowlesi antigens induce immune responses that delay parasitemia upon sporozoite challenge

Hansen, S., Womack, J., Scholz, I., Renner, A., Edgel, K. A., Xu, G., Ford, J. C., Grey, M., St. Laurent, B., Turner, J. M., Planer, S., Legasse, A. W., Richie, T. L., Aguiar, J. C., Axthelm, M., Villasante, E. D., Weiss, W., Edlefsen, P. T., Picker, L. & Frueh, K., Jan 1 2019, In : PLoS One. 14, 1, e0210252.

Research output: Contribution to journalArticle

10 Scopus citations

Enhancing safety of cytomegalovirus-based vaccine vectors by engaging host intrinsic immunity

Marshall, E., Malouli, D., Hansen, S., Gilbride, R. M., Hughes, C. M., Ventura, A. B., Ainslie, E., Selseth, A. N., Ford, J. C., Burke, D., Kreklywich, C. N., Womack, J., Legasse, A. W., Axthelm, M., Kahl, C., Streblow, D., Edlefsen, P. T., Picker, L. & Frueh, K., Jul 17 2019, In : Science Translational Medicine. 11, 501, eaaw2603.

Research output: Contribution to journalArticle

6 Scopus citations

Identification and functional characterization of a novel Fc gamma-binding glycoprotein in rhesus cytomegalovirus

Kolb, P., Sijmons, S., McArdle, M. R., Taher, H., Womack, J., Hughes, C., Ventura, A., Jarvis, M. A., Stahl-Hennig, C., Hansen, S., Picker, L., Malouli, D., Hengel, H. & Frueh, K., Feb 1 2019, In : Journal of virology. 93, 4, e0207718.

Research output: Contribution to journalArticle

2 Scopus citations

Immunometabolic signatures predict risk of progression to active tuberculosis and disease outcome

GC6-74 Consortium, Jan 1 2019, In : Frontiers in immunology. 10, MAR, 527.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Interferon-Gamma test for the detection of Mycobacterium tuberculosis complex infection in Macaca mulatta and other non-human primates

Yee, J. A. L., Prongay, K., Miles, B., Smedley, J., Hansen, S. G., Axthelm, M. K., Ardeshir, A., Van Rompay, K. K. A., Timmel, G. & Roberts, J. A., Aug 2019, In : Journal of medical primatology. 48, 4, p. 260-263 4 p.

Research output: Contribution to journalArticle

Vaccine-Mediated Inhibition of the Transporter Associated with Antigen Processing Is Insufficient To Induce Major Histocompatibility Complex E-Restricted CD8+ T Cells in Nonhuman Primates

Abdulhaqq, S. A., Wu, H., Schell, J. B., Hammond, K. B., Reed, J. S., Legasse, A. W., Axthelm, M. K., Park, B. S., Asokan, A., Früh, K., Hansen, S. G., Picker, L. J. & Sacha, J. B., Oct 1 2019, In : Journal of virology. 93, 19

Research output: Contribution to journalArticle

1 Scopus citations
2020

MHC-E-Restricted CD8+ T cells target Hepatitis B virus-infected human hepatocytes

Burwitz, B., Hashiguchi, P. K., Mansouri, M., Meyer, C., Gilbride, R. M., Biswas, S., Womack, J. L., Reed, J. S., Wu, H. L., Axthelm, M., Hansen, S. G., Picker, L. J., Frueh, K. & Sacha, J., Apr 15 2020, In : Journal of Immunology. 204, 8, p. 2169-2176 8 p.

Research output: Contribution to journalArticle