Sandra Rugonyi

Professor

  • 996 Citations
  • 17 h-Index
20012018
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Research Output 2001 2018

  • 996 Citations
  • 17 h-Index
  • 42 Article
  • 9 Conference contribution
  • 2 Chapter
  • 2 Review article
2018
1 Citation (Scopus)

Animal models for heart valve research and development

Kheradvar, A., Zareian, R., Kawauchi, S., Goodwin, R. L. & Rugonyi, S., Jan 1 2018, (Accepted/In press) In : Drug Discovery Today: Disease Models.

Research output: Contribution to journalArticle

Heart Valve Diseases
Heart Valves
Animal Models
Research
Epigenomics
1 Citation (Scopus)

Influence of blood flow on cardiac development

Courchaine, K., Rykiel, G. & Rugonyi, S., Sep 1 2018, In : Progress in Biophysics and Molecular Biology. 137, p. 95-110 16 p.

Research output: Contribution to journalReview article

Hemodynamics
Congenital Heart Defects
Embryonic Structures
Inventions
Cardiovascular System

Light-sheet fluorescence microscopy for the study of the murine heart

Ding, Y., Bailey, Z., Messerschmidt, V., Nie, J., Bryant, R., Rugonyi, S., Fei, P., Lee, J. & Hsiai, T. K., Sep 15 2018, In : Journal of Visualized Experiments. 2018, 139, e57769.

Research output: Contribution to journalArticle

Fluorescence microscopy
Lighting
Fluorescence Microscopy
Light
Ion Channels
1 Citation (Scopus)
Computational methods
blood flow
Blood
methodology
Hemodynamics
2017
15 Citations (Scopus)

Blood flow patterns underlie developmental heart defects

Midgett, M., Thornburg, K. & Rugonyi, S., Mar 13 2017, In : American Journal of Physiology - Heart and Circulatory Physiology. 312, 3, p. H632-H642

Research output: Contribution to journalArticle

Congenital Heart Defects
Embryonic Structures
Double Outlet Right Ventricle
Branchial Region
Teratogens
12 Citations (Scopus)
Hemodynamics
Endocardium
Confocal Microscopy
Electron Scanning Microscopy
Proteomics
4 Citations (Scopus)
Myofibrils
Myocardium
Hemodynamics
Proteomics
Renin-Angiotensin System
12 Citations (Scopus)

Intraluminal thrombus is associated with early rupture of abdominal aortic aneurysm

Haller, S. J., Crawford, J. D., Courchaine, K. M., Bohannan, C. J., Landry, G., Moneta, G. G., Azarbal, A. & Rugonyi, S., Jan 1 2017, (Accepted/In press) In : Journal of Vascular Surgery.

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Rupture
Thrombosis
Aneurysm
Blood Pressure
2016

A chicken embryo cardiac outflow tract atlas for registering changes due to abnormal blood flow

Carson, J. P., Rennie, M. Y., Danilchik, M., Thornburg, K. & Rugonyi, S., Oct 13 2016, 2016 38th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2016. Institute of Electrical and Electronics Engineers Inc., Vol. 2016-October. p. 1236-1239 4 p. 7590929

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Atlases
Chickens
Blood
Embryonic Structures
Congenital Heart Defects
3 Citations (Scopus)

A Geodesics-Based Surface Parameterization to Assess Aneurysm Progression

Phan, L., Courchaine, K., Azarbal, A., Vorp, D., Grimm, C. & Rugonyi, S., May 1 2016, In : Journal of Biomechanical Engineering. 138, 5, 054503.

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Parameterization
Aneurysm
Strain relaxation
Rupture
2 Citations (Scopus)

Changes in dynamic embryonic heart wall motion in response to outflow tract banding measured using video densitometry

Stovall, S., Midgett, M., Thornburg, K. & Rugonyi, S., Nov 1 2016, In : Journal of Biomedical Optics. 21, 11, 116003.

Research output: Contribution to journalArticle

blood flow
Optical microscopy
biodynamics
microscopy
heart diseases

Visualization of chicken embryo heart motion

Phan, L., Rugonyi, S. & Grimm, C., Sep 22 2016, (Accepted/In press) In : Computer Methods in Biomechanics and Biomedical Engineering: Imaging and Visualization. p. 1-15 15 p.

Research output: Contribution to journalArticle

Chickens
Embryonic Structures
Visualization
Hemodynamics
Parameterization
2015
9 Citations (Scopus)

4D subject-specific inverse modeling of the chick embryonic heart outflow tract hemodynamics

Goenezen, S., Chivukula, V. K., Midgett, M., Phan, L. & Rugonyi, S., Sep 11 2015, (Accepted/In press) In : Biomechanics and Modeling in Mechanobiology.

Research output: Contribution to journalArticle

Inverse Modeling
Hemodynamics
Blood Flow
Cardiac
Fluid Model

Analysis of 4D myocardial wall motion during early stages of chick heart development

Midgett, M. & Rugonyi, S., 2015, In : Methods in Molecular Biology. 1299, p. 191-212 22 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Growth
Datasets
7 Citations (Scopus)

Aortic outflow occlusion predicts rupture of abdominal aortic aneurysm

Crawford, J. D., Chivukula, V. K., Haller, S., Vatakhah, N., Bohannan, C. J., Moneta, G. G., Rugonyi, S. & Azarbal, A., Nov 25 2015, (Accepted/In press) In : Journal of Vascular Surgery.

Research output: Contribution to journalArticle

Abdominal Aortic Aneurysm
Rupture
Aortic Rupture
Chronic Obstructive Pulmonary Disease
Biomarkers
11 Citations (Scopus)

Blood flow through the embryonic heart outflow tract during cardiac looping in HH13-HH18 chicken embryos

Midgett, M., Chivukula, V. K., Dorn, C., Wallace, S. & Rugonyi, S., Oct 6 2015, In : Journal of the Royal Society Interface. 12, 111, 20150652.

Research output: Contribution to journalArticle

Chickens
Blood
Embryonic Structures
Hemodynamics
Shear deformation
2 Citations (Scopus)

Visualization techniques for the developing chicken heart

Phan, L., Grimm, C. & Rugonyi, S., 2015, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Springer Verlag, Vol. 9474. p. 35-44 10 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 9474).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Visualization
Embryo
Motion
Periodic Motion
Hemodynamics
2014
3 Citations (Scopus)

3D imaging of the early embryonic chicken heart with focused ion beam scanning electron microscopy

Rennie, M. Y., Gahan, C. G., Lopez, C., Thornburg, K. & Rugonyi, S., 2014, In : Microscopy and Microanalysis. 20, 4, p. 1111-1119 9 p.

Research output: Contribution to journalArticle

chickens
Focused ion beams
ion beams
Imaging techniques
Scanning electron microscopy
20 Citations (Scopus)

Blood flow dynamics reflect degree of outflow tract banding in Hamburger-Hamilton stage 18 chicken embryos

Midgett, M., Goenezen, S. & Rugonyi, S., Nov 6 2014, In : Journal of the Royal Society Interface. 11, 100, 0643.

Research output: Contribution to journalArticle

Hemodynamics
Chickens
Blood
Embryonic Structures
Cardiovascular system
31 Citations (Scopus)

Congenital heart malformations induced by hemodynamic altering surgical interventions

Midgett, M. & Rugonyi, S., 2014, In : Frontiers in Physiology. 5 JUL, 00287.

Research output: Contribution to journalArticle

Congenital Heart Defects
Hemodynamics
Ligation
Blood Pressure
Blood Flow Velocity
10 Citations (Scopus)

Improving the efficiency of abdominal aortic aneurysm wall stress computations

Zelaya, J. E., Goenezen, S., Dargon, P. T., Azarbal, A. & Rugonyi, S., Jul 9 2014, In : PLoS One. 9, 7, e101353.

Research output: Contribution to journalArticle

aneurysm
Abdominal Aortic Aneurysm
Aneurysm
Rupture
Abdominal Aorta
2013
18 Citations (Scopus)
Pulse Wave Analysis
Pulse
Chickens
Embryonic Structures
Blood Pressure

Hemodynamic forces regulate collagen deposition in the embryonic chicken outflow tract

Rennie, M. Y., Danilchik, M., Thornburg, K. & Rugonyi, S., 2013, ASME 2013 Summer Bioengineering Conference, SBC 2013. Vol. 1 A.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hemodynamics
Collagen
Chickens
Confocal microscopy
Chick Embryo
26 Citations (Scopus)

Hyperglycemia slows embryonic growth and suppresses cell cycle via cyclin D1 and p21

Scott-Drechsel, D. E., Rugonyi, S., Marks, D., Thornburg, K. & Hinds, M., Jan 2013, In : Diabetes. 62, 1, p. 234-242 9 p.

Research output: Contribution to journalArticle

Cyclin D1
Hyperglycemia
Cell Cycle
Glucose
Growth
2012
31 Citations (Scopus)

Biomechanics of early cardiac development

Goenezen, S., Rennie, M. Y. & Rugonyi, S., Nov 2012, In : Biomechanics and Modeling in Mechanobiology. 11, 8, p. 1187-1204 18 p.

Research output: Contribution to journalArticle

Biomechanics
Hemodynamics
Biomechanical Phenomena
Cardiac
Imaging techniques
41 Citations (Scopus)

Biomechanics of the chick embryonic heart outflow tract at HH18 using 4D optical coherence tomography imaging and computational modeling

Liu, A., Yin, X., Shi, L., Li, P., Thornburg, K., Wang, R. & Rugonyi, S., Jul 23 2012, In : PLoS One. 7, 7, e40869.

Research output: Contribution to journalArticle

Biomechanics
Optical tomography
tomography
Optical Coherence Tomography
Biomechanical Phenomena
11 Citations (Scopus)
embryos
Optical tomography
tomography
Tissue
Imaging techniques
13 Citations (Scopus)
Optical tomography
blood flow
strain rate
Strain rate
Blood
2011
28 Citations (Scopus)

Assessment of strain and strain rate in embryonic chick heart in vivo using tissue Doppler optical coherence tomography

Li, P., Liu, A., Shi, L., Yin, X., Rugonyi, S. & Wang, R. K., Nov 21 2011, In : Physics in Medicine and Biology. 56, 22, p. 7081-7092 12 p.

Research output: Contribution to journalArticle

Optical Coherence Tomography
Biomechanical Phenomena

Changes in biomechanical environment of cardiac cells in chick embryos after cardiac outflow tract banding

Liu, A., Thornburg, K., Wang, R. & Rugonyi, S., 2011, ASME 2011 Summer Bioengineering Conference, SBC 2011. PARTS A AND B ed. p. 363-364 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

17 Citations (Scopus)

Measurement of strain and strain rate in embryonic chick heart in vivo using spectral domain optical coherence tomography

Li, P., Yin, X., Shi, L., Liu, A., Rugonyi, S. & Wang, R. K., Aug 2011, In : IEEE Transactions on Biomedical Engineering. 58, 8, p. 2333-2338 6 p., 5766020.

Research output: Contribution to journalArticle

Optical tomography
Optical Coherence Tomography
Strain rate
Myocardium
Imaging techniques
31 Citations (Scopus)

Quantifying blood flow and wall shear stresses in the outflow tract of chick embryonic hearts

Liu, A., Nickerson, A., Troyer, A., Yin, X., Cary, R., Thornburg, K., Wang, R. & Rugonyi, S., Jun 2011, In : Computers and Structures. 89, 11-12, p. 855-867 13 p.

Research output: Contribution to journalArticle

Wall Shear Stress
Blood Flow
Cardiac
Shear stress
Blood
3 Citations (Scopus)

Refining shape correspondence for similar objects using strain

Phan, L., Knutsen, A. K., Bayly, P. V., Rugonyi, S. & Grimm, C., 2011, Eurographics Workshop on 3D Object Retrieval, 3DOR 2011 - co-event of Eurographics 2011. Eurographics Association, p. 17-24 8 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Refining
Tissue
13 Citations (Scopus)

The role of carrier number on the procoagulant activity of tissue factor in blood and plasma

Tormoen, G. W., Rugonyi, S., Gruber, A. & McCarty, O., Dec 2011, In : Physical Biology. 8, 6, 066005.

Research output: Contribution to journalArticle

Thromboplastin
S 2366
Thrombosis
Chromogenic Compounds
Factor VIIa
2010
54 Citations (Scopus)

Measurement of absolute blood flow velocity in outflow tract of HH18 chicken embryo based on 4D reconstruction using spectral domain optical coherence tomography

Ma, Z., Liu, A., Yin, X., Troyer, A., Thornburg, K., Wang, R. K. & Rugonyi, S., Oct 1 2010, In : Biomedical Optics Express. 1, 3, p. 798-811 14 p.

Research output: Contribution to journalArticle

chickens
Blood Flow Velocity
embryos
Optical Coherence Tomography
blood flow

Modeling the effect of hemodynamics on cardiac growth during embryonic development

Rugonyi, S. & Thornburg, K., 2010, Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010. p. 297-298 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Hemodynamics
Embryonic Development
Growth
12 Citations (Scopus)

Rational design of an ex vivo model of thrombosis

Berny, M. A., Patel, I. A., White-Adams, T. C., Simonson, P., Gruber, A., Rugonyi, S. & McCarty, O., Jun 2010, In : Cellular and Molecular Bioengineering. 3, 2, p. 187-189 3 p.

Research output: Contribution to journalArticle

Thrombosis
Occlusion
Animal Model
Platelets
Model
2 Citations (Scopus)
Platelets
Grafts
Mathematical models
Blood
Data structures

Wall motion influences flow pattern in the outflow tract of the chick embryonic heart tube

Liu, A., Wang, R., Thornburg, K. & Rugonyi, S., 2010, ASME 2010 Summer Bioengineering Conference, SBC 2010. PARTS A AND B ed. p. 225-226 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Flow patterns
2009
15 Citations (Scopus)
Hemodynamics
Shear Stress
Computational Model
Shear stress
Wall Shear Stress
50 Citations (Scopus)
Optical tomography
synchronism
Synchronization
tomography
Imaging techniques

Efficient synchronization and reconstruction of 4D non-gated cardiac images of chick embryos obtained from optical coherence tomography

Liu, A., Wang, R., Thornburg, K. & Rugonyi, S., 2009, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009. PART B ed. p. 1063-1064 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Optical tomography
Optical Coherence Tomography
Chick Embryo
Synchronization
116 Citations (Scopus)

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI

Tucker, E., Marzec, U. M., White, T. C., Hurst, S., Rugonyi, S., McCarty, O., Gailani, D., Gruber, A. & Hanson, S. R., Jan 22 2009, In : Blood. 113, 4, p. 936-944 9 p.

Research output: Contribution to journalArticle

Vascular Graft Occlusion
Factor XI
Grafts
Thrombin
Thrombosis
2008
64 Citations (Scopus)
Optical tomography
Optical Coherence Tomography
blood flow
veins
Ligation
7 Citations (Scopus)
Boundary layers
Blood
Mass transfer
Pharmaceutical Preparations
Biological Phenomena
10 Citations (Scopus)

Influence of liquid-layer thickness on pulmonary surfactant spreading and collapse

Siebert, T. A. & Rugonyi, S., Nov 15 2008, In : Biophysical Journal. 95, 10, p. 4549-4559 11 p.

Research output: Contribution to journalArticle

Pulmonary Surfactants
Pulmonary Atelectasis
Surface-Active Agents
Surface Tension
Exhalation
65 Citations (Scopus)

The biophysical function of pulmonary surfactant

Rugonyi, S., Biswas, S. C. & Hall, S. S., Nov 30 2008, In : Respiratory Physiology and Neurobiology. 163, 1-3, p. 244-255 12 p.

Research output: Contribution to journalArticle

Pulmonary Surfactants
Surface Tension
Surface-Active Agents
Adsorption
Exhalation
2007
23 Citations (Scopus)

Finite element modeling of blood flow-induced mechanical forces in the outflow tract of chick embryonic hearts

Liu, A., Rugonyi, S., Pentecost, J. O. & Thornburg, K., Jun 2007, In : Computers and Structures. 85, 11-14, p. 727-738 12 p.

Research output: Contribution to journalArticle

Finite Element Modeling
Blood Flow
Blood
Hemodynamics
Shear Stress

Surfactant spreading on a thin fluid film is sensitive to film thickness: Implications for in vivo pulmonary systems versus in vitro scenarios

Siebert, T. A. & Rugonyi, S., 2007, Proceedings of the ASME Summer Bioengineering Conference 2007, SBC 2007. p. 281-282 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Surface-Active Agents
Film thickness
Surface active agents
Fluids
2006

Alveolar Surface Mechanics

Hall, S. B. & Rugonyi, S., Jan 1 2006, Encyclopedia of Respiratory Medicine, Four-Volume Set. Elsevier Inc., p. 101-106 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mechanics
Surface-Active Agents
Surface Tension
Surface tension
Pulmonary Surfactants