Samantha Louey

Research Assistant Professor

  • 1458 Citations
  • 23 h-Index
20002019
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Research Output 2000 2019

  • 1458 Citations
  • 23 h-Index
  • 46 Article
  • 1 Chapter
  • 1 Conference contribution
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Article
2019
1 Citation (Scopus)
Thyroid Hormone Receptors
Cardiac Myocytes
Sheep
Somatomedins
Bromodeoxyuridine
2018

A 1 week IGF-1 infusion decreases arterial insulin concentrations but increases pancreatic insulin content and islet vascularity in fetal sheep

White, A., Louey, S., Chang, E. I., Boehmer, B. H., Goldstrohm, D., Jonker, S. & Rozance, P. J., Sep 1 2018, In : Physiological Reports. 6, 17, e13840.

Research output: Contribution to journalArticle

Somatomedins
Sheep
Insulin
Fetus
Islets of Langerhans
Maternal Exposure
Cardiac Myocytes
Testosterone
Fetus
Pregnancy
1 Citation (Scopus)
Cardiac Myocytes
Adenosine
Blood Vessels
Anemia
Heart Ventricles
Insulin-Like Growth Factor I
Cardiac Myocytes
Hypertension
Muscle Cells
Heart Ventricles
2016
14 Citations (Scopus)

Biological features of placental programming

Thornburg, K., Kolahi, K., Pierce, M., Valent, A., Drake, R. & Louey, S., Dec 1 2016, In : Placenta. 48, p. S47-S53

Research output: Contribution to journalArticle

Placenta
Fetal Development
Fetus
Chronic Disease
Placental Insufficiency
15 Citations (Scopus)

Endocrine and other physiologic modulators of perinatal cardiomyocyte endowment

Jonker, S. & Louey, S., 2016, In : Journal of Endocrinology. 228, 1, p. R1-R18

Research output: Contribution to journalArticle

Financial Management
Cardiac Myocytes
Parturition
Rodentia
Sheep
2 Citations (Scopus)

Functional adaptations of the coronary microcirculation to anaemia in fetal sheep

Jonker, S., Davis, L., Soman, D., Belcik, J. T., Davidson, B. P., Atkinson, T. T., Wilburn, A., Louey, S., Giraud, G. & Lindner, J., Nov 1 2016, In : Journal of Physiology. 594, 21, p. 6165-6174 10 p.

Research output: Contribution to journalArticle

Microcirculation
Anemia
Sheep
Fetus
Hyperemia
15 Citations (Scopus)
Trophoblasts
long chain fatty acids
placenta
Placenta
Fatty Acids
2015
Heart Valves
Fetal Development
Aortic Valve
Mitral Valve
Sheep
1 Citation (Scopus)

Theophylline Pharmacokinetics in Foetal Sheep: Maternal Metabolic Capacity is the Principal Driver

Dubois, B., Louey, S., Giraud, G., Cherala, G. & Jonker, S., Oct 1 2015, In : Basic and Clinical Pharmacology and Toxicology. 117, 4, p. 226-233 8 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Theophylline
Sheep
Mothers
Fetus
23 Citations (Scopus)

Timing of cardiomyocyte growth, maturation, and attrition in perinatal sheep

Jonker, S., Louey, S., Giraud, G., Thornburg, K. & Faber, J. J., Oct 1 2015, In : FASEB Journal. 29, 10, p. 4346-4357 12 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Sheep
Muscle Cells
Parturition
Growth
2014
13 Citations (Scopus)
Phosphatidylinositol 3-Kinases
Cardiac Myocytes
Somatomedins
Sheep
Phosphorylation
2013
15 Citations (Scopus)
Amniotic Fluid
Sheep
Urine
Amnion
Active Biological Transport
17 Citations (Scopus)

Uteroplacental circulation and fetal vascular function and development

Thornburg, K. & Louey, S., 2013, In : Current Vascular Pharmacology. 11, 5, p. 748-757 10 p.

Research output: Contribution to journalArticle

Placental Circulation
Blood Vessels
Umbilicus
Pregnancy
Fetus
2012
16 Citations (Scopus)
Thyroid Hormones
Cardiac Myocytes
Sheep
Pregnancy
Thyronines
27 Citations (Scopus)

Restriction of placental vasculature in a non-human primate: A unique model to study placental plasticity

Roberts, V., Rasanen, J., Novy, M. J., Frias, A., Louey, S., Morgan, T., Thornburg, K., Spindel, E. & Grigsby, P., Jan 2012, In : Placenta. 33, 1, p. 73-76 4 p.

Research output: Contribution to journalArticle

Placenta
Primates
Umbilicus
Doppler Ultrasonography
Growth
70 Citations (Scopus)

Thyroid hormone drives fetal cardiomyocyte maturation

Chattergoon, N., Giraud, G., Louey, S., Stork, P., Fowden, A. L. & Thornburg, K., Jan 2012, In : FASEB Journal. 26, 1, p. 397-408 12 p.

Research output: Contribution to journalArticle

Thyroid Hormones
Cardiac Myocytes
Cyclin D1
Cells
Thyronines
2011
3 Citations (Scopus)

Insignificant response of the fetal placental circulation to arterial hypotension in sheep

Faber, J. J., Anderson, D., Louey, S., Thornburg, K. & Giraud, G., Oct 2011, In : Journal of Applied Physiology. 111, 4, p. 1042-1047 6 p.

Research output: Contribution to journalArticle

Enalaprilat
Placental Circulation
Hypotension
Sheep
Arterial Pressure
13 Citations (Scopus)

Maternal malnutrition and placental insufficiency induce global downregulation of gene expression in fetal kidneys

Denisenko, O., Lin, B., Louey, S., Thornburg, K., Bomsztyk, K. & Bagby, S., Apr 2011, In : Journal of Developmental Origins of Health and Disease. 2, 2, p. 124-133 10 p.

Research output: Contribution to journalArticle

Placental Insufficiency
Malnutrition
Down-Regulation
Mothers
Kidney
54 Citations (Scopus)

Regulation of the cardiomyocyte population in the developing heart

Thornburg, K., Jonker, S., O'Tierney, P., Chattergoon, N., Louey, S., Faber, J. & Giraud, G., Jul 2011, In : Progress in Biophysics and Molecular Biology. 106, 1, p. 289-299 11 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Atrial Natriuretic Factor
Population
Angiotensin II
Cell Cycle
2010
27 Citations (Scopus)

Atrial natriuretic peptide inhibits angiotensin II-stimulated proliferation in fetal cardiomyocytes

O'Tierney, P. F., Chattergoon, N., Louey, S., Giraud, G. & Thornburg, K., Aug 2010, In : Journal of Physiology. 588, 15, p. 2879-2889 11 p.

Research output: Contribution to journalArticle

Atrial Natriuretic Factor
Cardiac Myocytes
Angiotensin II
MAP Kinase Kinase 3
Extracellular Signal-Regulated MAP Kinases
32 Citations (Scopus)

Cardiomyocyte enlargement, proliferation and maturation during chronic fetal anaemia in sheep

Jonker, S., Giraud, M. K., Giraud, G., Chattergoon, N., Louey, S., Davis, L., Faber, J. J. & Thornburg, K., Jan 2010, In : Experimental Physiology. 95, 1, p. 131-139 9 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Anemia
Sheep
Fetus
Tissue Expansion
20 Citations (Scopus)
Fetal Heart
Enalaprilat
Sheep
Cell Cycle
Fetus
128 Citations (Scopus)

Review: The Placenta is a Programming Agent for Cardiovascular Disease

Thornburg, K., O'Tierney, P. F. & Louey, S., Mar 2010, In : Placenta. 31, SUPPL.

Research output: Contribution to journalArticle

Placenta
Fetal Heart
Heart Diseases
Cardiovascular Diseases
Growth
2009
22 Citations (Scopus)

Responses of amniotic fluid volume and its four major flows to lung liquid diversion and amniotic infusion in the ovine fetus

Robertson, P., Faber, J. J., Brace, R. A., Louey, S., Hohimer, A. R., Davis, L. & Anderson, D., Jan 2009, In : Reproductive Sciences. 16, 1, p. 88-93 6 p.

Research output: Contribution to journalArticle

Amniotic Fluid
Sheep
Fetus
Lung
Lung Volume Measurements
2007
94 Citations (Scopus)

Myocyte enlargement, differentiation, and proliferation kinetics in the fetal sheep heart

Jonker, S., Zhang, L., Louey, S., Giraud, G., Thornburg, K. & Faber, J. J., Mar 2007, In : Journal of Applied Physiology. 102, 3, p. 1130-1142 13 p.

Research output: Contribution to journalArticle

Fetal Heart
Muscle Cells
Sheep
Cardiac Myocytes
Growth
76 Citations (Scopus)
Placental Insufficiency
Cardiac Myocytes
Sheep
Cell Cycle
Fetus
44 Citations (Scopus)
Fetal Development
Cardiac Myocytes
Muscle Cells
Sheep
Hypertension
2006
75 Citations (Scopus)

Cortisol stimulates cell cycle activity in the cardiomyocyte of the sheep fetus

Giraud, G., Louey, S., Jonker, S., Schultz, J. & Thornburg, K., 2006, In : Endocrinology. 147, 8, p. 3643-3649 7 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Hydrocortisone
Sheep
Cell Cycle
Fetus
2005
19 Citations (Scopus)

Fetal growth restriction induced by chronic placental insufficiency has long-term effects on the retina but not the optic nerve

Loeliger, M., Duncan, J., Louey, S., Cock, M., Hording, R. & Rees, S., Sep 2005, In : Investigative Ophthalmology and Visual Science. 46, 9, p. 3300-3308 9 p.

Research output: Contribution to journalArticle

Placental Insufficiency
Optic Nerve
Fetal Development
Retina
Pregnancy
23 Citations (Scopus)

Fetal roots of cardiac disease

Thornburg, K. & Louey, S., Jul 2005, In : Heart. 91, 7, p. 867-868 2 p.

Research output: Contribution to journalArticle

Vascular Endothelium
Fetal Development
Cardiac Myocytes
Myocardial Ischemia
Coronary Disease
31 Citations (Scopus)

Long term consequences of low birthweight on postnatal growth, adiposity and brain weight at maturity in sheep

Louey, S., Cock, M. L. & Harding, R., Feb 2005, In : Journal of Reproduction and Development. 51, 1, p. 59-68 10 p.

Research output: Contribution to journalArticle

low birth weight
Adiposity
Low Birth Weight Infant
adiposity
Sheep
49 Citations (Scopus)

The prenatal environment and later cardiovascular disease

Louey, S. & Thornburg, K., Sep 2005, In : Early Human Development. 81, 9, p. 745-751 7 p.

Research output: Contribution to journalArticle

Cardiovascular Diseases
Dyslipidemias
Growth
Lipid Metabolism
Glucocorticoids
2004
22 Citations (Scopus)

Effects of exposure to chronic placental insufficiency on the postnatal brain and retina in sheep

Duncan, J. R., Cock, M. L., Loeliger, M., Louey, S., Harding, R. & Rees, S. M., Nov 2004, In : Journal of Neuropathology and Experimental Neurology. 63, 11, p. 1131-1143 13 p.

Research output: Contribution to journalArticle

Placental Insufficiency
Retina
Sheep
Brain
Cerebellum
81 Citations (Scopus)

Fetal Growth Restriction Has Long-Term Effects on Postnatal Lung Structure in Sheep

Maritz, G. S., Cock, M. L., Louey, S., Suzuki, K. & Harding, R., Feb 2004, In : Pediatric Research. 55, 2, p. 287-295 9 p.

Research output: Contribution to journalArticle

Fetal Development
Sheep
Lung
Parturition
Blood-Air Barrier
50 Citations (Scopus)

Nephron Endowment and Filtration Surface Area in the Kidney after Growth Restriction of Fetal Sheep

Mitchell, E. K. L., Louey, S., Cock, M. L., Harding, R. & Black, M. J., May 2004, In : Pediatric Research. 55, 5, p. 769-773 5 p.

Research output: Contribution to journalArticle

Nephrons
Financial Management
Fetal Development
Sheep
Kidney
10 Citations (Scopus)

Pulmonary elastin synthesis and deposition in developing and mature sheep: Effects of intrauterine growth restriction

Cock, M. L., Joyce, B. J., Hooper, S. B., Wallace, M. J., Gagnon, R., Brace, R. A., Louey, S. & Harding, R., Jul 2004, In : Experimental Lung Research. 30, 5, p. 405-418 14 p.

Research output: Contribution to journalArticle

Elastin
Sheep
Lung
Growth
Tropoelastin
2003
3 Citations (Scopus)

Chronic placental insufficiency and foetal growth restriction lead to long-term effects on postnatal retinal structure

Loeliger, M., Louey, S., Cock, M. L., Harding, R. & Rees, S. M., Jun 2003, In : Clinical and Experimental Ophthalmology. 31, 3, p. 250-253 4 p.

Research output: Contribution to journalArticle

Placental Insufficiency
Fetal Development
Retina
Amacrine Cells
Parturition
25 Citations (Scopus)

Postnatal development of arterial pressure: Influence of the intrauterine environment

Louey, S., Cock, M. L. & Harding, R., Feb 2003, In : Archives of Physiology and Biochemistry. 111, 1, p. 53-60 8 p.

Research output: Contribution to journalArticle

Arterial Pressure
Parturition
Placental Insufficiency
Sheep
Animals
2001
60 Citations (Scopus)

Compromised respiratory function in postnatal lambs after placental insufficiency and intrauterine growth restriction

Joyce, B. J., Louey, S., Davey, M. G., Cock, M. L., Hooper, S. B. & Harding, R., 2001, In : Pediatric Research. 50, 5, p. 641-649 9 p.

Research output: Contribution to journalArticle

Placental Insufficiency
Growth
Functional Residual Capacity
Low Birth Weight Infant
Thoracic Wall
83 Citations (Scopus)

Effects of fetal growth restriction on lung development before and after birth: A morphometric analysis

Maritz, G. S., Cock, M. L., Louey, S., Joyce, B. J., Albuquerque, C. A. & Harding, R., 2001, In : Pediatric Pulmonology. 32, 3, p. 201-210 10 p.

Research output: Contribution to journalArticle

Fetal Development
Parturition
Lung
Pregnancy
Fetus
24 Citations (Scopus)

Postnatal outcomes in term and preterm lambs following fetal growth restriction

Cock, M. L., Camm, E., Louey, S., Joyce, B. & Harding, R., 2001, In : Clinical and Experimental Pharmacology and Physiology. 28, 11, p. 931-937 7 p.

Research output: Contribution to journalArticle

Fetal Development
Growth
Premature Birth
Fetus
Lung Compliance
2000
32 Citations (Scopus)

Effects of intra-uterine growth restriction on the control of breathing and lung development after birth

Harding, R., Tester, M. L., Moss, T. J., Davey, M. G., Louey, S., Joyce, B., Hooper, S. B. & Maritz, G., Jan 2000, In : Clinical and Experimental Pharmacology and Physiology. 27, 1-2, p. 114-119 6 p.

Research output: Contribution to journalArticle

Respiration
Parturition
Lung
Growth
Hypercapnia
70 Citations (Scopus)

Placental insufficiency and fetal growth restriction lead to postnatal hypotension and altered postnatal growth in sheep

Louey, S., Cock, M. L., Stevenson, K. M. & Harding, R., 2000, In : Pediatric Research. 48, 6, p. 808-814 7 p.

Research output: Contribution to journalArticle

Placental Insufficiency
Fetal Development
Hypotension
Sheep
Growth
45 Citations (Scopus)

The compromised intra-uterine environment: Implications for future lung health

Harding, R., Cock, M. L., Louey, S., Joyce, B. J., Davey, M. G., Albuquerque, C. A., Hooper, S. B. & Maritz, G. S., 2000, In : Clinical and Experimental Pharmacology and Physiology. 27, 12, p. 965-974 10 p.

Research output: Contribution to journalArticle

Lung
Health
Lung Compliance
Pulmonary Surfactant-Associated Protein C
Blood-Air Barrier