Ryan Li

Assistant Professor

  • 1789 Citations
  • 16 h-Index
20082019
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Research Output 2008 2019

  • 1789 Citations
  • 16 h-Index
  • 41 Article
  • 1 Review article
2019

Association between Sarcopenia and Mortality in Patients Undergoing Surgical Excision of Head and Neck Cancer

Stone, L., Olson, B., Mowery, A., Krasnow, S., Jiang, A., Li, R., Schindler, J., Wax, M., Andersen, P., Marks, D., Achim, V. & Clayburgh, D., Jan 1 2019, In : JAMA Otolaryngology - Head and Neck Surgery.

Research output: Contribution to journalArticle

Sarcopenia
Head and Neck Neoplasms
Mortality
Survival
Odds Ratio

Contemporary Treatment of Locally Advanced Oral Cancer

Kim, D. & Li, R., Apr 1 2019, In : Current treatment options in oncology. 20, 4, 32.

Research output: Contribution to journalReview article

Mouth Neoplasms
Chemoradiotherapy
Induction Chemotherapy
Organ Preservation
Adjuvant Radiotherapy

Wound Complications in Head and Neck Squamous Cell Carcinomas After Anti–PD-1 Therapy

Hwang, V., Mendez, E., Chow, L. Q. M., Futran, N. D., Andersen, P., Li, R., Divi, V. & Rodriguez, C. P., Jan 1 2019, In : Laryngoscope.

Research output: Contribution to journalArticle

Wounds and Injuries
Mandible
Therapeutics
Osteoradionecrosis
Laryngoscopes
2018
3 Citations (Scopus)

Comparison of Opioid Utilization Patterns after Major Head and Neck Procedures between Hong Kong and the United States

Li, R., Loyo Li, M., Leon, E., Ng, C. W. K., Shindo, M., Manzione, K., Andersen, P., Clayburgh, D., Wax, M. & Chan, J. Y. K., Jan 1 2018, (Accepted/In press) In : JAMA Otolaryngology - Head and Neck Surgery. p. E1-E6

Research output: Contribution to journalArticle

Hong Kong
Opioid Analgesics
Neck
Head
Odds Ratio
1 Citation (Scopus)

HEY1 is expressed independent of NOTCH1 and is associated with poor prognosis in head and neck squamous cell carcinoma

Rettig, E. M., Bishop, J. A., Agrawal, N., Chung, C. H., Sharma, R., Zamuner, F., Li, R., Koch, W. M., Califano, J. A., Guo, T., Gaykalova, D. A. & Fakhry, C., Jul 1 2018, In : Oral Oncology. 82, p. 168-175 8 p.

Research output: Contribution to journalArticle

Mutation
Neoplasms
Proportional Hazards Models
Carcinoma, squamous cell of head and neck
Staining and Labeling

Is Improved Insurance Coverage a Fleeting Opportunity?

Li, R. & McConnell, K. J., Jan 1 2018, (Accepted/In press) In : JAMA Otolaryngology - Head and Neck Surgery.

Research output: Contribution to journalArticle

Insurance Coverage
7 Citations (Scopus)

Long-term functional and quality-of-life outcomes after transoral robotic surgery in patients with oropharyngeal cancer

Achim, V., Bolognone, R., Palmer, A. D., Graville, D., Light, T. J., Li, R., Gross, N., Andersen, P. & Clayburgh, D., Jan 1 2018, In : JAMA Otolaryngology - Head and Neck Surgery. 144, 1, p. 18-27 10 p.

Research output: Contribution to journalArticle

Oropharyngeal Neoplasms
Robotics
Quality of Life
Deglutition
Adjuvant Radiotherapy
5 Citations (Scopus)

Opioid Prescribing Practice and Needs in Thyroid and Parathyroid Surgery

Shindo, M., Lim, J., Leon, E., Moneta, L., Li, R. & Quintinalla-Diek, L., Jan 1 2018, (Accepted/In press) In : JAMA Otolaryngology - Head and Neck Surgery.

Research output: Contribution to journalArticle

Opioid Analgesics
Thyroid Gland
Morphine
Thyroidectomy
Parathyroidectomy
1 Citation (Scopus)

Staging HPV-related oropharyngeal cancer: Validation of AJCC-8 in a surgical cohort

Geltzeiler, M., Bertolet, M., Albergotti, W., Gleysteen, J., Olson, B., Persky, M., Gross, N., Li, R., Andersen, P., Kim, S., Ferris, R. L., Duvvuri, U. & Clayburgh, D., Sep 1 2018, In : Oral Oncology. 84, p. 82-87 6 p.

Research output: Contribution to journalArticle

Oropharyngeal Neoplasms
Survival
Neoplasms
Squamous Cell Carcinoma
Proportional Hazards Models

Technical refinements and outcomes of the modified anterior septal transplant

Loyo, M., Markey, J. D., Gerecci, D., El Rassi, E., Li, R., Sullivan, C. B. & Wang, T., Jan 1 2018, In : JAMA Facial Plastic Surgery. 20, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

Nasal Obstruction
Symptom Assessment
Transplants
Nose
Tertiary Care Centers
2017
3 Citations (Scopus)

A randomized controlled trial of corticosteroids for pain after transoral robotic surgery

Clayburgh, D., Stott, W., Bolognone, R., Palmer, A., Achim, V., Troob, S., Li, R., Brickman, D., Graville, D., Andersen, P. & Gross, N. D., Nov 1 2017, In : Laryngoscope. 127, 11, p. 2558-2564 7 p.

Research output: Contribution to journalArticle

Robotics
Length of Stay
Adrenal Cortex Hormones
Randomized Controlled Trials
Pain
2 Citations (Scopus)

Candida Meningitis After Transsphenoidal Surgery: A Single-Institution Case Series and Literature Review

Bridges, K. J., Li, R., Fleseriu, M. & Cetas, J., Dec 1 2017, In : World Neurosurgery. 108, p. 41-49 9 p.

Research output: Contribution to journalArticle

Candida
Meningitis
Neurosurgical Procedures
Flucytosine
Indwelling Catheters
1 Citation (Scopus)

Human papillomavirus tumour status is not associated with a positive depression screen for patients with oropharyngeal cancer

Qualliotine, J. R., Califano, J. A., Li, R., Gold, D., Messing, B., Lee, G., Ha, P. & Fakhry, C., Sep 1 2017, In : Journal of Laryngology and Otology. 131, 9, p. 760-767 8 p.

Research output: Contribution to journalArticle

Oropharyngeal Neoplasms
Neoplasms
Demography
Population

Osteocutaneous radial forearm free flap in nonmandible head and neck reconstruction

Ahmad, F. I., Means, C., Labby, A. B., Troob, S., Gonzalez, J. D., Kim, M., Li, R. & Wax, M., 2017, (Accepted/In press) In : Head and Neck.

Research output: Contribution to journalArticle

Free Tissue Flaps
Forearm
Neck
Head
Mandible
11 Citations (Scopus)

Prognostic indication of sarcopenia for wound complication after total laryngectomy

Achim, V., Bash, J., Mowery, A., Guimaraes, A., Li, R., Schindler, J., Wax, M., Andersen, P. & Clayburgh, D., Dec 1 2017, In : JAMA Otolaryngology - Head and Neck Surgery. 143, 12, p. 1159-1165 7 p.

Research output: Contribution to journalArticle

Sarcopenia
Laryngectomy
Wounds and Injuries
Cutaneous Fistula
Albumins
2015
21 Citations (Scopus)

Cleaved NOTCH1 expression pattern in head and neck squamous cell carcinoma is associated with NOTCH1 mutation, HPV status, and high-risk features

Rettig, E. M., Chung, C. H., Bishop, J. A., Howard, J. D., Sharma, R., Li, R., Douville, C., Karchin, R., Izumchenko, E., Sidransky, D., Koch, W., Califano, J., Agrawal, N. & Fakhry, C., Apr 1 2015, In : Cancer Prevention Research. 8, 4, p. 287-295 9 p.

Research output: Contribution to journalArticle

Mutation
Odds Ratio
Confidence Intervals
Neoplasms
Negative Staining
28 Citations (Scopus)

Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke

Li, R., Faden, D. L., Fakhry, C., Langelier, C., Jiao, Y., Wang, Y., Wilkerson, M. D., Pedamallu, C. S., Old, M., Lang, J., Loyo, M., Ahn, S. M., Tan, M., Gooi, Z., Chan, J., Richmon, J., Wood, L. D., Hruban, R. H., Bishop, J., Westra, W. H. & 11 othersChung, C. H., Califano, J., Gourin, C. G., Bettegowda, C., Meyerson, M., Papadopoulos, N., Kinzler, K. W., Vogelstein, B., Derisi, J. L., Koch, W. M. & Agrawal, N., Nov 1 2015, In : Head and Neck. 37, 11, p. 1642-1649 8 p.

Research output: Contribution to journalArticle

Metagenomics
Tongue
Smoke
Squamous Cell Carcinoma
Tongue Neoplasms
93 Citations (Scopus)

Oncologic outcomes after transoral robotic surgery a multi-institutional study

De Almeida, J. R., Li, R., Magnuson, J. S., Smith, R. V., Moore, E., Lawson, G., Remacle, M., Ganly, I., Kraus, D. H., Teng, M. S., Miles, B. A., White, H., Duvvuri, U., Ferris, R. L., Mehta, V., Kiyosaki, K., Damrose, E. J., Wang, S. J., Kupferman, M. E., Koh, Y. W. & 2 othersGenden, E. M. & Holsinger, F. C., Dec 1 2015, In : JAMA Otolaryngology - Head and Neck Surgery. 141, 12, p. 1043-1051 9 p.

Research output: Contribution to journalArticle

Robotics
Survival
Head and Neck Neoplasms
Oropharyngeal Neoplasms
Radiotherapy
17 Citations (Scopus)

Outlier analysis defines zinc finger gene family DNA methylation in tumors and saliva of head and neck cancer patients

Gaykalova, D. A., Vatapalli, R., Wei, Y., Tsai, H. L., Wang, H., Zhang, C., Hennessey, P. T., Guo, T., Tan, M., Li, R., Ahn, J., Khan, Z., Westra, W. H., Bishop, J. A., Zaboli, D., Koch, W. M., Khan, T., Ochs, M. F. & Califano, J. A., Nov 6 2015, In : PLoS One. 10, 11, e0142148.

Research output: Contribution to journalArticle

zinc finger motif
Zinc Fingers
squamous cell carcinoma
DNA methylation
DNA Methylation
2 Citations (Scopus)

Reduction of pharyngocutaneous fistulae in laryngectomy patients by a comprehensive performance improvement intervention

Li, R., Zhou, X. C., Fakhry, C., Negrin, J., Lee, G., Ha, P., Blanco, R., Saunders, J. & Califano, J. A., Dec 1 2015, In : Otolaryngology - Head and Neck Surgery (United States). 153, 6, p. 927-934 8 p.

Research output: Contribution to journalArticle

Laryngectomy
Fistula
Perioperative Care
Antibiotic Prophylaxis
Tertiary Care Centers
6 Citations (Scopus)

Transoral Endoscopic Head and Neck Surgery: The Contemporary Treatment of Head and Neck Cancer

Lim, G. C., Holsinger, F. C. & Li, R., Dec 1 2015, In : Hematology/Oncology Clinics of North America. 29, 6, p. 1075-1092 18 p.

Research output: Contribution to journalArticle

Patient Care Team
Oropharynx
Microsurgery
Neoplasm Staging
Laser Therapy
2014
104 Citations (Scopus)

Activation of the NOTCH pathway in head and neck cancer

Sun, W., Gaykalova, D. A., Ochs, M. F., Mambo, E., Arnaoutakis, D., Liu, Y., Loyo, M., Agrawal, N., Howard, J., Li, R., Ahn, S., Fertig, E., Sidransky, D., Houghton, J., Buddavarapu, K., Sanford, T., Choudhary, A., Darden, W., Adai, A., Latham, G. & 6 othersBishop, J., Sharma, R., Westra, W. H., Hennessey, P., Chung, C. H. & Califano, J. A., Feb 15 2014, In : Cancer Research. 74, 4, p. 1091-1104 14 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Mutation
Ligands
Genes
Neoplasms
12 Citations (Scopus)

A learner-centered educational curriculum improves resident performance on the otolaryngology training examination

Reh, D. D., Ahmed, A., Li, R., Laeeq, K. & Bhatti, N. I., Oct 1 2014, In : Laryngoscope. 124, 10, p. 2262-2267 6 p.

Research output: Contribution to journalArticle

Otolaryngology
Curriculum
Longitudinal Studies
Linear Models
Neck
15 Citations (Scopus)

Expression microarray analysis reveals alternative splicing of LAMA3 and DST genes in head and neck squamous cell carcinoma

Li, R., Ochs, M. F., Ahn, S. M., Hennessey, P., Tan, M., Soudry, E., Gaykalova, D. A., Uemura, M., Brait, M., Shao, C., Westra, W., Bishop, J., Fertig, E. J. & Califano, J. A., Mar 27 2014, In : PLoS One. 9, 3, e91263.

Research output: Contribution to journalArticle

alternative splicing
squamous cell carcinoma
Alternative Splicing
Microarray Analysis
Microarrays
43 Citations (Scopus)

Human papillomavirus (HPV) status of non-tobacco related squamous cell carcinomas of the lateral tongue

Poling, J. S., Ma, X. J., Bui, S., Luo, Y., Li, R., Koch, W. M. & Westra, W. H., 2014, In : Oral Oncology. 50, 4, p. 306-310 5 p.

Research output: Contribution to journalArticle

Tongue
Squamous Cell Carcinoma
Messenger RNA
Smoking
Tongue Neoplasms
43 Citations (Scopus)

Novel insight into mutational landscape of head and neck squamous cell carcinoma

Gaykalova, D. A., Mambo, E., Choudhary, A., Houghton, J., Buddavarapu, K., Sanford, T., Darden, W., Adai, A., Hadd, A., Latham, G., Danilova, L. V., Bishop, J., Li, R., Westra, W. H., Hennessey, P., Koch, W. M., Ochs, M. F., Califano, J. A. & Sun, W., Mar 25 2014, In : PLoS One. 9, 3, e93102.

Research output: Contribution to journalArticle

squamous cell carcinoma
neck
mutation
Mutation
Genes
118 Citations (Scopus)

The clinical impact of HPV tumor status upon head and neck squamous cell carcinomas

Benson, E., Li, R., Eisele, D. & Fakhry, C., 2014, In : Oral Oncology. 50, 6, p. 565-574 10 p.

Research output: Contribution to journalArticle

Squamous Cell Neoplasms
Neoplasms
Head and Neck Neoplasms
Head
Demography
2013
16 Citations (Scopus)

Distinct epidemiologic characteristics of oral tongue cancer patients

Li, R., Koch, W. M., Fakhry, C. & Gourin, C. G., May 2013, In : Otolaryngology - Head and Neck Surgery (United States). 148, 5, p. 792-796 5 p.

Research output: Contribution to journalArticle

Tongue Neoplasms
Mouth Neoplasms
Odds Ratio
Mouth
Cross-Sectional Studies
39 Citations (Scopus)

EDNRB and DCC salivary rinse hypermethylation has a similar performance as expert clinical examination in discrimination of oral cancer/dysplasia versus benign lesions

Schussel, J., Zhou, X. C., Zhang, Z., Pattani, K., Bermudez, F., Jean-Charles, G., McCaffrey, T., Padhya, T., Phelan, J., Spivakovsky, S., Brait, M., Li, R., Bowne, H. Y., Goldberg, J. D., Rolnitzky, L., Robbins, M., Kerr, A. R., Sirois, D. & Califano, J. A., Jun 15 2013, In : Clinical Cancer Research. 19, 12, p. 3268-3275 8 p.

Research output: Contribution to journalArticle

Endothelin B Receptors
Mouth Neoplasms
Colorectal Neoplasms
Methylation
Area Under Curve
34 Citations (Scopus)

Lessons learned from next-generation sequencing in head and neck cancer

Loyo, M., Li, R., Bettegowda, C., Pickering, C. R., Frederick, M. J., Myers, J. N. & Agrawal, N., Mar 2013, In : Head and Neck. 35, 3, p. 454-463 10 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Mutation
Exome
High-Throughput Nucleotide Sequencing
Critical Pathways
4 Citations (Scopus)

Short-term outcomes and cost of care of treatment of head and neck paragangliomas

Chan, J. Y. K., Li, R. & Gourin, C. G., Jul 2013, In : Laryngoscope. 123, 7, p. 1645-1651 7 p.

Research output: Contribution to journalArticle

Paraganglioma
Health Care Costs
Neck
Odds Ratio
Head
11 Citations (Scopus)

The Effect of tumor subsite on short-term outcomes and costs of care after oral cancer surgery

Li, R., Fakhry, C., Koch, W. M. & Gourin, C. G., Jul 2013, In : Laryngoscope. 123, 7, p. 1652-1659 8 p.

Research output: Contribution to journalArticle

Oral Surgery
Mouth Neoplasms
Odds Ratio
Costs and Cost Analysis
Mouth
2012
26 Citations (Scopus)

Objective assessment in residency-based training for transoral robotic surgery.

Curry, M., Malpani, A., Li, R., Tantillo, T., Jog, A., Blanco, R., Ha, P. K., Califano, J., Kumar, R. & Richmon, J., 2012, In : The Laryngoscope. 122, 10, p. 2184-2192 9 p.

Research output: Contribution to journalArticle

Robotics
Internship and Residency
Learning Curve
Otolaryngology
Operating Rooms
17 Citations (Scopus)

Suprabasin Is Hypomethylated and Associated with Metastasis in Salivary Adenoid Cystic Carcinoma

Shao, C., Tan, M., Bishop, J. A., Liu, J., Bai, W., Gaykalova, D. A., Ogawa, T., Vikani, A. R., Agrawal, Y., Li, R., Kim, M. S., Westra, W. H., Sidransky, D., Califano, J. A. & Ha, P. K., Nov 7 2012, In : PLoS One. 7, 11, e48582.

Research output: Contribution to journalArticle

decitabine
trichostatin A
Adenoid Cystic Carcinoma
CpG Islands
Methylation

Transoral approaches to the oropharynx: The revival of surgery for oropharyngeal carcinoma

Chan, J. Y. K., Li, R. & Richmon, J. D., Sep 2012, In : Otorinolaringologia. 62, 3, p. 149-159 11 p.

Research output: Contribution to journalArticle

Oropharynx
Oropharyngeal Neoplasms
Carcinoma
Papillomaviridae
Organ Preservation
18 Citations (Scopus)

Transoral Endoscopic Surgery: New Surgical Techniques for Oropharyngeal Cancer

Li, R. & Richmon, J. D., Aug 2012, In : Otolaryngologic Clinics of North America. 45, 4, p. 823-844 22 p.

Research output: Contribution to journalArticle

Oropharyngeal Neoplasms
Microsurgery
Robotics
Deglutition
Cosmetics
2011
17 Citations (Scopus)

Endoscopic transvestibular paramandibular exploration of the infratemporal fossa and parapharyngeal space: A minimally invasive approach to the middle cranial base

Chan, J. Y. K., Li, R., Lim, M., Hinojosa, A. Q. & Boahene, K. D., Oct 2011, In : Laryngoscope. 121, 10, p. 2075-2080 6 p.

Research output: Contribution to journalArticle

Skull Base
Maxillary Artery
Synovial Chondromatosis
Foramen Ovale
Mucoepidermoid Carcinoma
994 Citations (Scopus)

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

Agrawal, N., Frederick, M. J., Pickering, C. R., Bettegowda, C., Chang, K., Li, R., Fakhry, C., Xie, T. X., Zhang, J., Wang, J., Zhang, N., El-Naggar, A. K., Jasser, S. A., Weinstein, J. N., Treviño, L., Drummond, J. A., Muzny, D. M., Wu, Y., Wood, L. D., Hruban, R. H. & 11 othersWestra, W. H., Koch, W. M., Califano, J. A., Gibbs, R. A., Sidransky, D., Vogelstein, B., Velculescu, V. E., Papadopoulos, N., Wheeler, D. A., Kinzler, K. W. & Myers, J. N., Aug 26 2011, In : Science. 333, 6046, p. 1154-1157 4 p.

Research output: Contribution to journalArticle

Exome
Mutation
Neoplasms
Tobacco Use
Carcinoma, squamous cell of head and neck
2010

Lymphomatous neoplasm within the carotid sheath

Jolley, V., Li, R. & Richmon, J. D., Oct 2010, In : Laryngoscope. 120, SUPPL. 3

Research output: Contribution to journalArticle

Lymphoma
Neck
Head
Neoplasms
Mediastinum
2008
10 Citations (Scopus)

Gingival hypertrophy: a solitary manifestation of scurvy

Li, R., Byers, K. & Walvekar, R. R., Nov 2008, In : American Journal of Otolaryngology - Head and Neck Medicine and Surgery. 29, 6, p. 426-428 3 p.

Research output: Contribution to journalArticle

Gingival Hypertrophy
Ascorbic Acid Deficiency
Scurvy
Gingiva
Vegetables
54 Citations (Scopus)

Role of surgery in limited (T1-2, N0-1) cancers of the oropharynx

Walvekar, R. R., Li, R., Gooding, W. E., Gibson, M. K., Heron, D., Johnson, J. T. & Ferris, R. L., Dec 2008, In : Laryngoscope. 118, 12, p. 2129-2134 6 p.

Research output: Contribution to journalArticle

Oropharyngeal Neoplasms
Squamous Cell Neoplasms
Tonsillar Neoplasms
Tongue Neoplasms
Drug Therapy
13 Citations (Scopus)

Unresectable hepatocellular carcinoma with a solitary metastasis to the mandible

Li, R., Walvekar, R. R., Nalesnik, M. A. & Gamblin, T. C., Apr 2008, In : American Surgeon. 74, 4, p. 346-349 4 p.

Research output: Contribution to journalArticle

Mandible
Hepatocellular Carcinoma
Neoplasm Metastasis
Jaw
Masseter Muscle