Rosalie Sears

Professor

  • 5838 Citations
  • 34 h-Index
1988 …2020
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Fingerprint Dive into the research topics where Rosalie Sears is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Protein Phosphatase 2 Medicine & Life Sciences
Proto-Oncogene Proteins c-myc Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Tumor Suppressor Proteins Medicine & Life Sciences
Proteins Medicine & Life Sciences
Oncogene Proteins Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences

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Projects 1994 2020

Pancreatic Neoplasms
Serine
Adenocarcinoma
Phosphorylation
Neoplasms
Ubiquitination
Ubiquitin
Phosphorylation
Ligases
Carcinogenesis
Phosphorylation
Threonine
Serine
Proto-Oncogene Proteins c-myc
Neoplasms
Protein Stability
Protein Phosphatase 2
Phosphorylation
Serine
Neoplasms

Research Output 1988 2019

  • 5838 Citations
  • 34 h-Index
  • 73 Article
  • 2 Chapter
  • 2 Conference contribution
  • 1 Editorial
4 Citations (Scopus)

Activation of PP2A and inhibition of mTOR synergistically reduce MYC signaling and decrease tumor growth in pancreatic ductal adenocarcinoma

Allen-Petersen, B. L., Risom, T., Feng, Z., Wang, Z., Jenny, Z. P., Thoma, M. C., Pelz, K. R., Morton, J. P., Sansom, O. J., Lopez, C., Sheppard, B., Christensen, D. J., Ohlmeyer, M., Narla, G. & Sears, R., Jan 1 2019, In : Cancer Research. 79, 1, p. 209-219 11 p.

Research output: Contribution to journalArticle

Protein Phosphatase 2
Adenocarcinoma
Phosphoric Monoester Hydrolases
Phosphotransferases
Growth
2 Citations (Scopus)

A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

Auciello, F. R., Bulusu, V., Oon, C., Tait-Mulder, J., Berry, M., Bhattacharyya, S., Tumanov, S., Allen-Petersen, B. L., Link, J., Kendsersky, N. D., Vringer, E., Schug, M., Novo, D., Hwang, R. F., Evans, R. M., Nixon, C., Dorrell, C., Morton, J. P., Norman, J. C., Sears, R. & 2 othersKamphorst, J. J. & Sherman, M., May 1 2019, In : Cancer discovery. 9, 5, p. 617-627 11 p.

Research output: Contribution to journalArticle

Open Access
Adenocarcinoma
Neoplasms
Wound Healing
Lipids
Pancreatic Stellate Cells

GRB7 dependent proliferation of basal-like, HER-2 positive human breast cancer cell lines is mediated in part by HER-1 signaling

Luoh, S-W., Wagoner, W., Wang, X., Hu, Z., Lai, X., Chin, K-Y., Sears, R. & Ramsey, E., Jan 1 2019, In : Molecular Carcinogenesis.

Research output: Contribution to journalArticle

Breast Neoplasms
Cell Line
Small Interfering RNA
Growth
GRB7 Adaptor Protein
1 Citation (Scopus)

Modeling differentiation-state transitions linked to therapeutic escape in triple-negative breast cancer

Chapman, M. P., Risom, T., Aswani, A. J., Langer, E. M., Sears, R. & Tomlin, C. J., Mar 1 2019, In : PLoS computational biology. 15, 3, p. e1006840

Research output: Contribution to journalArticle

Open Access
Triple Negative Breast Neoplasms
State Transition
Breast Cancer
breast neoplasms
cancer
1 Citation (Scopus)

Modeling Tumor Phenotypes In Vitro with Three-Dimensional Bioprinting

Langer, E. M., Allen-Petersen, B. L., King, S. M., Kendsersky, N. D., Turnidge, M. A., Kuziel, G. M., Riggers, R., Samatham, R., Amery, T. S., Jacques, S., Sheppard, B., Korkola, J., Muschler, J., Thibault, G., Chang, Y. H., Gray, J., Presnell, S. C., Nguyen, D. G. & Sears, R., Jan 15 2019, In : Cell Reports. 26, 3, p. 608-623.e6

Research output: Contribution to journalArticle

Bioprinting
Tumors
Tissue
Phenotype
Scaffolds