• 8540 Citations
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1977 …2020

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116 Scopus citations

3,4-Epoxy-1-butene, a reactive metabolite of 1,3-butadiene, induces somatic mutations in Xpc-null mice

Wickliffe, J. K., Galbert, L. A., Ammenheuser, M. M., Herring, S. M., Xie, J., Masters, O. E., Friedberg, E. C., Lloyd, R. S. & Ward, J. B., Jan 1 2006, In : Environmental and Molecular Mutagenesis. 47, 1, p. 67-70 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle

Vartanian, V., Tumova, J., Dobrzyn, P., Dobrzyn, A., Nakabeppu, Y., Lloyd, R. S. & Sampath, H., Jul 1 2017, In : PLoS One. 12, 7, e0181687.

Research output: Contribution to journalArticle

11 Scopus citations

8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction

Sampath, H., Vartanian, V., Rollins, M. R., Sakumi, K., Nakabeppu, Y. & Lloyd, R. S., Dec 17 2012, In : PloS one. 7, 12, e51697.

Research output: Contribution to journalArticle

63 Scopus citations

A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ

Yamanaka, K., Dorjsuren, D., Eoff, R. L., Egli, M., Maloney, D. J., Jadhav, A., Simeonov, A. & Lloyd, R. S., Oct 8 2012, In : PloS one. 7, 10, e45032.

Research output: Contribution to journalArticle

22 Scopus citations

Active-site determination of a pyrimidine dimer glycosylase

Garvish, J. F. & Lloyd, R. S., Jan 21 2000, In : Journal of molecular biology. 295, 3, p. 479-488 10 p.

Research output: Contribution to journalArticle

13 Scopus citations

A DNA Adenine Methyltransferase of Escherichia coli That Is Cell Cycle Regulated and Essential for Viability

Kossykh, V. G. & Lloyd, R. S., Apr 1 2004, In : Journal of bacteriology. 186, 7, p. 2061-2067 7 p.

Research output: Contribution to journalArticle

10 Scopus citations

A DNA adenine methyltransferase of Escherichia coli that is cell cycle regulated and essential for viability.

Kossykh, V. G. & Lloyd, R. S., Sep 2004, In : Journal of Bacteriology. 186, 18, p. 6340 1 p.

Research output: Contribution to journalArticle

Aflatoxin-Guanine DNA Adducts and Oxidatively Induced DNA Damage in Aflatoxin-Treated Mice in Vivo as Measured by Liquid Chromatography-Tandem Mass Spectrometry with Isotope Dilution

Coskun, E., Jaruga, P., Vartanian, V., Erdem, O., Egner, P. A., Groopman, J. D., Lloyd, R. S. & Dizdaroglu, M., Jan 1 2018, (Accepted/In press) In : Chemical Research in Toxicology.

Research output: Contribution to journalArticle

7 Scopus citations

A gene that partially complements xeroderma pigmentosum group A cells maps to human chromosome 8

Kaur, G. P., Rinaldy, A., Lloyd, R. S. & Athwal, R. S., Jul 1 1992, In : Somatic Cell and Molecular Genetics. 18, 4, p. 371-379 9 p.

Research output: Contribution to journalArticle

8 Scopus citations

A model of sensitivity: 1,3-Butadiene increases mutant frequencies and genomic damage in mice lacking a functional microsomal epoxide hydrolase gene

Wickliffe, J. K., Ammenheuser, M. M., Salazar, J. J., Abdel-Rahman, S. Z., Hastings-Smith, D. A., Postlethwait, E. M., Lloyd, R. S. & Ward, J. B., Sep 18 2003, In : Environmental and Molecular Mutagenesis. 42, 2, p. 106-110 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

A modified quantitative polymerase chain reaction assay for measuring gene-specific repair of UV photoproducts in human cells

McCarthy, M. J., Rosenblatt, J. I. & Lloyd, R. S., May 15 1996, In : Mutation Research - DNA Repair. 363, 1, p. 57-66 10 p.

Research output: Contribution to journalArticle

29 Scopus citations
4 Scopus citations

Analysis of t4 endonuclease v homologs from a variety of chlorella virus strains

Forgacs, E., Kodira, C., Van Elten, J. L. & Lloyd, R. S., Dec 1 1996, In : FASEB Journal. 10, 6, p. A965

Research output: Contribution to journalArticle

29 Scopus citations

A physical map of belomycin-specific fragmentation sites on PM2 bacteriophage DNA

Lloyd, R. S., Haidle, C. W., Robberson, D. L. & Dodson, M. L., Jan 1978, In : Current Microbiology: An International Journal. 1, 1, p. 45-50 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

AP lyases and dRPases: Commonality of mechanism

Piersen, C. E., McCullough, A. K. & Lloyd, R. S., Feb 16 2000, In : Mutation Research - DNA Repair. 459, 1, p. 43-53 11 p.

Research output: Contribution to journalArticle

77 Scopus citations

A xeroderma pigmentosum complementation group A related gene: confirmation using monoclonal antibodies against the cyclobutane dimer and (6-4) photoproduct

Mori, T., Rinaldy, T. L., Athwal, R. S., Kaur, G. P., Nikaido, O., Lloyd, R. S. & Rinaldy, A., Jan 1993, In : Mutation Research-DNA Repair. 293, 2, p. 143-150 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Backbone dynamics of DNA containing 8-oxoguanine: Importance for substrate recognition by base excision repair glycosylases

Dodson, M. L. & Lloyd, R. S., Dec 19 2001, In : Mutation Research - DNA Repair. 487, 3-4, p. 93-108 16 p.

Research output: Contribution to journalArticle

7 Scopus citations

Base excision repair of cyclobutane pyrimidine dimers

Lloyd, R. S., Sep 11 1998, In : Mutation Research - DNA Repair. 408, 3, p. 159-170 12 p.

Research output: Contribution to journalArticle

19 Scopus citations
59 Scopus citations

Bleomycin fragmentation of duplex DNA occurs as staggered single-strand scissions

Lloyd, R. S., Haidle, C. W. & Robberson, D. L., Nov 1979, In : Gene. 7, 3-4, p. 303-316 14 p.

Research output: Contribution to journalArticle

10 Scopus citations

Bleomycin-induced alkaline-labile damage and direct strand breakage in covalent-circular DNA

Lloyd, R. S., Hewitt, R. R. & Haidle, C. W., Jan 1 1977, In : Federation Proceedings. 36, 3, p. No. 2229

Research output: Contribution to journalArticle

1 Scopus citations

Bleomycin-induced Alkaline-labile Damage and Direct Strand Breakage of PM2 DNA

Lloyd, R. S., Haidle, C. W. & Hewitt, R. R., Oct 1978, In : Cancer Research. 38, 10, p. 3191-3196 6 p.

Research output: Contribution to journalArticle

60 Scopus citations

Bleomycin-induced breakage of closed-circular DNA

Bearden, J. C., Lloyd, R. S. & Haidle, C. W., Mar 21 1977, In : Biochemical and Biophysical Research Communications. 75, 2, p. 442-448 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Bleomycin-mediated DNA cross-links are dependent on closed-circular molecules with superhelical turns

Lloyd, R. S., Robberson, D. L. & Haidle, C. W., Feb 1981, In : Chemico-Biological Interactions. 34, 1, p. 39-46 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Bleomycin-Specific Fragmentation of Double-Stranded DNA

Lloyd, R. S., Haidle, C. W. & Robberson, D. L., Jan 1 1978, In : Biochemistry. 17, 10, p. 1890-1896 7 p.

Research output: Contribution to journalArticle

172 Scopus citations

Butadiene-induced intrastrand DNA cross-links: A possible role in deletion mutagenesis

Carmical, J. R., Kowalczyk, A., Zou, Y., Van Houten, B., Nechev, L. V., Harris, C. M., Harris, T. M. & Lloyd, R. S., Jun 30 2000, In : Journal of Biological Chemistry. 275, 26, p. 19482-19489 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Carbinolamine formation and dehydration in a dna repair enzyme active site

Dodson, M. L., Walker, R. C. & Lloyd, R. S., Feb 22 2012, In : PloS one. 7, 2, e31377.

Research output: Contribution to journalArticle

Catalysts of DNA Strand Cleavage at Apurinic/Apyrimidinic Sites

Minko, I., Jacobs, A. C., De Leon, A. R., Gruppi, F., Donley, N., Harris, T. M., Rizzo, C. J., McCullough, A. & Lloyd, R. S., Jul 1 2016, In : Scientific Reports. 6, 28894.

Research output: Contribution to journalArticle

6 Scopus citations

Catalytic role of escherichia cou muty gene product in dna mismatch repair

Manuel, R. C. & Lloyd, R. S., Dec 1 1996, In : FASEB Journal. 10, 6, p. A964

Research output: Contribution to journalArticle

Characterization of a novel cis-syn and trans-syn-II pyrimidine dimer glycosylase/AP lyase from a eukaryotic algal virus, Paramecium bursaria chlorella virus-1

McCullough, A. K., Romberg, M. T., Nyaga, S., Wei, Y., Wood, T. G., Taylor, J. S., Van Etten, J. L., Dodson, M. L. & Lloyd, R. S., May 22 1998, In : Journal of Biological Chemistry. 273, 21, p. 13136-13142 7 p.

Research output: Contribution to journalArticle

42 Scopus citations

Characterization of Cdnas, Mrnas, and Proteins Related to Human Liver Microsomal Cytochrome P-450 (s)-mephenytoin 4′-Hydroxylase

Ged, C., Umbenhauer, D. R., Bellew, T. M., Bork, R. W., Srivastava, P. K., Shinriki, N., Lloyd, R. S. & Guengerich, F. P., Sep 1 1988, In : Biochemistry. 27, 18, p. 6929-6940 12 p.

Research output: Contribution to journalArticle

122 Scopus citations

Characterization of mRNA species related to human liver cytochrome P-450 nifedipine oxidase and the regulation of catalytic activity

Bork, R. W., Muto, T., Beaune, P. H., Srivastava, P. K., Lloyd, R. S. & Guengerich, F. P., Jan 1 1989, In : Journal of Biological Chemistry. 264, 2, p. 910-919 10 p.

Research output: Contribution to journalArticle

122 Scopus citations

Characterization of rare NEIL1 variants found in East Asian populations

Minko, I. G., Vartanian, V. L., Tozaki, N. N., Linde, O. K., Jaruga, P., Coskun, S. H., Coskun, E., Qu, C., He, H., Xu, C., Chen, T., Song, Q., Jiao, Y., Stone, M. P., Egli, M., Dizdaroglu, M., McCullough, A. K. & Lloyd, R. S., Jul 2019, In : DNA Repair. 79, p. 32-39 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Chlorella virus PBCV-1 encodes a homolog of the bacteriophage T4 UV damage repair gene denV

Furuta, M., Schrader, J. O., Schrader, H. S., Kokjohn, T. A., Nyaga, S., McCullough, A. K., Lloyd, R. S., Burbank, D. E., Landstein, D., Lane, L. & Van Etten, J. L., Apr 1 1997, In : Applied and Environmental Microbiology. 63, 4, p. 1551-1556 6 p.

Research output: Contribution to journalArticle

52 Scopus citations
20 Scopus citations

Cloning, overexpression, and biochemical characterization of the catalytic domain of MutY

Manuel, R. C. & Lloyd, R. S., Sep 16 1997, In : Biochemistry. 36, 37, p. 11140-11152 13 p.

Research output: Contribution to journalArticle

72 Scopus citations

Cloning and expression of the 3′ portion of the T4 denV gene as a lacZ fusion gene

Stephen Lloyd, R. & Augustine, M. L., Mar 1986, In : Mutation Research DNA Repair Reports. 165, 2, p. 89-100 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Cloning and Sequence Determination of a Complementary DNA Related to Human Liver Microsomal Cytochrome P-450 S-Mephenytoin 4-Hydroxylase

Umbenhauer, D. R., Martin, M. V., Lloyd, R. S. & Guengerich, F. P., Jan 1 1987, In : Biochemistry. 26, 4, p. 1094-1099 6 p.

Research output: Contribution to journalArticle

99 Scopus citations

Community outreach as an iterative dialogue among scientists and communities in the Texas gulf coast region

Sullivan, J., Diamond, P. D., Kaplan, C. L., Mader, T. J., Santa, R. K. & Lloyd, R. S., Nov 2003, In : Mutation Research - Reviews in Mutation Research. 544, 2-3, p. 331-338 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Comparative evaluation of the bioreactivity and mutagenic spectra of acrolein-derived α-HOPdG and γ-HOPdG regioisomeric deoxyguanosine adducts

Sanchez, A. M., Minko, I. G., Kurtz, A. J., Kanuri, M., Moriya, M. & Lloyd, R. S., Aug 1 2003, In : Chemical Research in Toxicology. 16, 8, p. 1019-1028 10 p.

Research output: Contribution to journalArticle

58 Scopus citations

Comparison of the efficiency of synthesis past single bulky DNA adducts in vivo and in vitro by the polymerase III holoenzyme

Latham, G. J., McNees, A. G., De Corte, B., Harris, C. M., Harris, T. M., O'Donnell, M. & Stephen Lloyd, R., Oct 29 1996, In : Chemical Research in Toxicology. 9, 7, p. 1167-1175 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) l,N 2-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA

Huang, H., Wang, H., Lloyd, R. S., Rizzo, C. J. & Stone, M. P., Jan 1 2009, In : Chemical Research in Toxicology. 22, 1, p. 187-200 14 p.

Research output: Contribution to journalArticle

11 Scopus citations

Consequences of Molecular Engineering Enhanced DNA Binding in a DNA Repair Enzyme

Nickell, C., Prince, M. A. & Lloyd, R. S., Jan 1 1992, In : Biochemistry. 31, 17, p. 4189-4198 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Conserved features of selenoprotein P cDNA

Hill, K. E., Lloyd, R. S. & Burk, R. F., Jan 1 1993, In : Biochemical Society transactions. 21, 4, p. 832-835 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
Open Access
150 Scopus citations

Cytochrome P-450 enzymes involved in genetic polymorphism of drug oxidation in humans

Guengerich, F. P., Beaune, P. H., Umbenhauer, D. R., Churchill, P. F., Bork, R. W., Dannan, G. A., Knodell, R. G., Lloyd, R. S. & Martin, M. V., Jan 1 1987, In : Biochemical Society transactions. 15, 4, p. 576-578 3 p.

Research output: Contribution to journalArticle

16 Scopus citations

Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion

Mori, H., Ouchida, R., Hijikata, A., Kitamura, H., Ohara, O., Li, Y., Gao, X., Yasui, A., Lloyd, R. S. & Wang, J. Y., Nov 2 2009, In : DNA Repair. 8, 11, p. 1328-1332 5 p.

Research output: Contribution to journalArticle

17 Scopus citations
36 Scopus citations