• 8170 Citations
  • 48 h-Index
1977 …2018
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Research Output 1977 2018

  • 8170 Citations
  • 48 h-Index
  • 239 Article
  • 2 Chapter
  • 1 Conference contribution
  • 1 Review article
2018
2 Citations

Modulation of UVB-induced Carcinogenesis by Activation of Alternative DNA Repair Pathways

Sha, Y., Vartanian, V., Owen, N., Mengden Koon, S. J., Calkins, M. J., Thompson, C. S., Mirafzali, Z., Mir, S., Goldsmith, L. E., He, H., Luo, C., Brown, S. M., Doetsch, P. W., Kaempf, A., Lim, J. Y., McCullough, A. K. & Lloyd, R. S., Dec 1 2018, In : Scientific Reports. 8, 1, 705.

Research output: Contribution to journalArticle

Nuclear Localization Signals
DNA Repair
Carcinogenesis
Liposomes
Cell-Penetrating Peptides

Processing of N5-substituted formamidopyrimidine DNA adducts by DNA glycosylases NEIL1 and NEIL3

Minko, I., Christov, P. P., Li, L., Stone, M. P., McCullough, A. & Lloyd, R. S., Jan 1 2018, (Accepted/In press) In : DNA Repair.

Research output: Contribution to journalArticle

DNA Glycosylases
DNA Adducts
Aflatoxin B1
Mechlorethamine
Processing

The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue

Komakula, S. S. B., Tumova, J., Kumaraswamy, D., Burchat, N., Vartanian, V., Ye, H., Dobrzyn, A., Lloyd, R. S. & Sampath, H., Dec 1 2018, In : Scientific Reports. 8, 1, 14886.

Research output: Contribution to journalArticle

White Adipose Tissue
DNA Repair
DNA Glycosylases
Obesity
Phenotype
2017
5 Citations

8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle

Vartanian, V., Tumova, J., Dobrzyn, P., Dobrzyn, A., Nakabeppu, Y., Lloyd, R. S. & Sampath, H., Jul 1 2017, In : PLoS One. 12, 7, e0181687.

Research output: Contribution to journalArticle

DNA Glycosylases
glycosylases
Lipid Metabolism
Metabolism
Muscle
2 Citations

Error-prone replication bypass of the imidazole ring-opened formamidopyrimidine deoxyguanosine adduct

Sha, Y., Minko, I. G., Malik, C. K., Rizzo, C. J. & Lloyd, R. S., May 1 2017, In : Environmental and Molecular Mutagenesis. 58, 4, p. 182-189 8 p.

Research output: Contribution to journalArticle

Deoxyguanosine
Mutation
Nucleotides
Escherichia coli
Mutagens
3 Citations

Mutagenic potential of nitrogen mustard-induced formamidopyrimidine DNA adduct: Contribution of the non-canonical α-anomer

Minko, I. G., Rizzo, C. J. & Stephen Lloyd, R., Jan 1 2017, In : Journal of Biological Chemistry. 292, 46, p. 18790-18799 10 p.

Research output: Contribution to journalArticle

Mechlorethamine
DNA Adducts
Mutagenesis
Escherichia coli
Primates
5 Citations

NEIL1 protects against aflatoxin-induced hepatocellular carcinoma in mice

Vartanian, V., Minko, I. G., Chawanthayatham, S., Egner, P. A., Lin, Y. C., Earley, L. F., Makar, R., Eng, J. R., Camp, M. T., Li, L., Stone, M. P., Lasarev, M. R., Groopman, J. D., Croy, R. G., Essigmann, J. M., McCullough, A. K. & Lloyd, R. S., Apr 18 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 16, p. 4207-4212 6 p.

Research output: Contribution to journalArticle

Aflatoxins
Hepatocellular Carcinoma
DNA Glycosylases
DNA Repair
Xeroderma Pigmentosum
2016
2 Citations

Catalysts of DNA Strand Cleavage at Apurinic/Apyrimidinic Sites

Minko, I. G., Jacobs, A. C., De Leon, A. R., Gruppi, F., Donley, N., Harris, T. M., Rizzo, C. J., McCullough, A. K. & Lloyd, R. S., Jul 1 2016, In : Scientific Reports. 6, 28894.

Research output: Contribution to journalArticle

DNA Glycosylases
Deoxyribose
DNA Cleavage
Single-Stranded DNA Breaks
Purines

DNA polymerase ζ limits chromosomal damage and promotes cell survival following aflatoxin exposure

Lin, Y. C., Owen, N., Minko, I. G., Lange, S. S., Li, L., Stone, M. P., Wood, R. D., McCullough, A. K. & Lloyd, R. S., Nov 29 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 48, p. 13774-13779 6 p.

Research output: Contribution to journalArticle

Aflatoxin B1
Aflatoxins
Cell Survival
Chromatids
Epoxy Compounds
2 Citations

Enhanced sensitivity of Neil1−/− mice to chronic UVB exposure

Calkins, M. J., Vartanian, V., Owen, N., Kirkali, G., Jaruga, P., Dizdaroglu, M., McCullough, A. K. & Lloyd, R. S., Dec 1 2016, In : DNA Repair. 48, p. 43-50 8 p.

Research output: Contribution to journalArticle

Reactive Oxygen Species
Deoxyribonuclease (Pyrimidine Dimer)
Repair
DNA
DNA Damage
2015
17 Citations

Small Molecule Inhibitors of 8-Oxoguanine DNA Glycosylase-1 (OGG1)

Donley, N., Jaruga, P., Coskun, E., Dizdaroglu, M., McCullough, A. K. & Lloyd, R. S., Oct 16 2015, In : ACS Chemical Biology. 10, 10, p. 2334-2343 10 p.

Research output: Contribution to journalArticle

DNA Glycosylases
Molecules
Repair
DNA Repair
DNA
2014
17 Citations

Error-prone replication bypass of the primary aflatoxin B1 DNA adduct, AFB1-N7-Gua

Lin, Y. C., Li, L., Makarova, A. V., Burgers, P. M., Stone, M. P. & Lloyd, R. S., Jun 27 2014, In : Journal of Biological Chemistry. 289, 26, p. 18497-18506 10 p.

Research output: Contribution to journalArticle

Aflatoxin B1
Hepatocellular Carcinoma
Geographical regions
Mutation
Aflatoxins
16 Citations

Molecular basis of aflatoxin-induced mutagenesis-role of the aflatoxin B1-formamidopyrimidine adduct

Lin, Y. C., Li, L., Makarova, A. V., Burgers, P. M., Stone, M. P. & Stephen Lloyd, R., 2014, In : Carcinogenesis. 35, 7, p. 1461-1468 8 p., bgu003.

Research output: Contribution to journalArticle

Aflatoxin B1
Aflatoxins
Mutagenesis
Genomic Instability
Site-Directed Mutagenesis
2 Citations

Pyrosequencing: Applicability for studying DNA damage-induced mutagenesis

Minko, I. G., Earley, L. F., Larlee, K. E., Lin, Y. C. & Lloyd, R. S., Oct 1 2014, In : Environmental and Molecular Mutagenesis. 55, 8, p. 601-608 8 p.

Research output: Contribution to journalArticle

Mutagenesis
DNA Damage
DNA
Primates
Mutation
2013
15 Citations

Inhibition of DNA glycosylases via small molecule purine analogs

Jacobs, A. C., Calkins, M. J., Jadhav, A., Dorjsuren, D., Maloney, D., Simeonov, A., Jaruga, P., Dizdaroglu, M., McCullough, A. K. & Stephen Lloyd, R., Dec 9 2013, In : PLoS One. 8, 12, e81667.

Research output: Contribution to journalArticle

DNA Glycosylases
glycosylases
purines
Molecules
DNA

Inhibition of HIV-1 Reverse Transcriptase-Catalyzed Synthesis by Intercalated DNA Benzo[a]Pyrene 7,8-Dihydrodiol-9,10-Epoxide Adducts

Chary, P., Beard, W. A., Wilson, S. H. & Lloyd, R. S., Sep 19 2013, In : PLoS One. 8, 9, e72131.

Research output: Contribution to journalArticle

7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
RNA-directed DNA polymerase
Human immunodeficiency virus 1
epoxides
HIV-1
11 Citations

Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity

Ketkar, A., Zafar, M. K., Maddukuri, L., Yamanaka, K., Banerjee, S., Egli, M., Choi, J. Y., Lloyd, R. S. & Eoff, R. L., Feb 18 2013, In : Chemical Research in Toxicology. 26, 2, p. 221-232 12 p.

Research output: Contribution to journalArticle

Leukotrienes
Biosynthesis
DNA-Directed DNA Polymerase
5-Lipoxygenase-Activating Protein Inhibitors
Genomic Instability
13 Citations

Mutagenic spectra arising from replication bypass of the 2,6-diamino-4-hydroxy-N5-methyl formamidopyrimidine adduct in primate cells

Earley, L. F., Minko, I. G., Christov, P. P., Rizzo, C. J. & Lloyd, R. S., Jul 15 2013, In : Chemical Research in Toxicology. 26, 7, p. 1108-1114 7 p.

Research output: Contribution to journalArticle

Primates
Nucleotides
Genetic Vectors
Mutagenesis
Oligodeoxyribonucleotides
2 Citations

Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the sulfolobus solfataricus DNA polymerase Dpo4

Shanmugam, G., Minko, I. G., Banerjee, S., Christov, P. P., Kozekov, I. D., Rizzo, C. J., Lloyd, R. S., Egli, M. & Stone, M. P., Sep 16 2013, In : Chemical Research in Toxicology. 26, 9, p. 1348-1360 13 p.

Research output: Contribution to journalArticle

Sulfolobus solfataricus
DNA-Directed DNA Polymerase
Deoxyguanosine
Nucleotides
DNA
1 Citations

Sequence context modulation of polycyclic aromatic hydrocarbon-induced mutagenesis

Chary, P., Stone, M. P. & Lloyd, R. S., Oct 2013, In : Environmental and Molecular Mutagenesis. 54, 8, p. 652-658 7 p.

Research output: Contribution to journalArticle

7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
Polycyclic Aromatic Hydrocarbons
Mutagenesis
Codon
DNA Replication
18 Citations

Translesion synthesis past acrolein-derived DNA adducts by human mitochondrial DNA polymerase γ

Kasiviswanathan, R., Minko, I. G., Lloyd, R. S. & Copeland, W. C., May 17 2013, In : Journal of Biological Chemistry. 288, 20, p. 14247-14255 9 p.

Research output: Contribution to journalArticle

Acrolein
DNA Adducts
Mitochondrial DNA
Purine Nucleotides
DNA-Directed DNA Polymerase
2012
48 Citations

8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction

Sampath, H., Vartanian, V., Rollins, M. R., Sakumi, K., Nakabeppu, Y. & Lloyd, R. S., Dec 17 2012, In : PLoS One. 7, 12, e51697.

Research output: Contribution to journalArticle

DNA Glycosylases
glycosylases
obesity
Obesity
Fats
17 Citations

A Comprehensive Strategy to Discover Inhibitors of the Translesion Synthesis DNA Polymerase κ

Yamanaka, K., Dorjsuren, D., Eoff, R. L., Egli, M., Maloney, D. J., Jadhav, A., Simeonov, A. & Lloyd, R. S., Oct 8 2012, In : PLoS One. 7, 10, e45032.

Research output: Contribution to journalArticle

DNA-directed DNA polymerase
DNA-Directed DNA Polymerase
synthesis
DNA
acrolein

Carbinolamine formation and dehydration in a dna repair enzyme active site

Dodson, M. L., Walker, R. C. & Lloyd, R. S., Feb 22 2012, In : PLoS One. 7, 2, e31377.

Research output: Contribution to journalArticle

Mechanics
Dehydration
active sites
Catalytic Domain
Repair
11 Citations

DNA polymerase β gap-filling translesion DNA synthesis

Chary, P., Beard, W. A., Wilson, S. H. & Lloyd, R. S., Dec 17 2012, In : Chemical Research in Toxicology. 25, 12, p. 2744-2754 11 p.

Research output: Contribution to journalArticle

DNA Polymerase beta
DNA
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
Stereochemistry
Polycyclic Aromatic Hydrocarbons
24 Citations

Regulation of DNA glycosylases and their role in limiting disease

Sampath, H., McCullough, A. K. & Stephen Lloyd, R., Apr 2012, In : Free Radical Research. 46, 4, p. 460-478 19 p.

Research output: Contribution to journalArticle

DNA Glycosylases
DNA Repair
DNA Damage
Repair
DNA
16 Citations

Replication bypass of N 2-deoxyguanosine interstrand cross-links by human DNA polymerases η and ι

Klug, A. R., Harbut, M. B., Lloyd, R. S. & Minko, I. G., Mar 19 2012, In : Chemical Research in Toxicology. 25, 3, p. 755-762 8 p.

Research output: Contribution to journalArticle

Deoxyguanosine
DNA-Directed DNA Polymerase
DNA
Acrolein
Nitrogen
9 Citations

Replication of the 2,6-diamino-4-hydroxy- N 5-(methyl)- formamidopyrimidine (MeFapy-dGuo) adduct by eukaryotic DNA polymerases

Christov, P. P., Yamanaka, K., Choi, J. Y., Takata, K. I., Wood, R. D., Guengerich, F. P., Lloyd, R. S. & Rizzo, C. J., Aug 20 2012, In : Chemical Research in Toxicology. 25, 8, p. 1652-1661 10 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Nucleotides
Mutagenesis
DNA Adducts
Genomic Instability
2011
4 Citations

Modulation of the processive abasic site lyase activity of a pyrimidine dimer glycosylase

Ryabinina, O. P., Minko, I. G., Lasarev, M. R., McCullough, A. K. & Lloyd, R. S., Oct 10 2011, In : DNA Repair. 10, 10, p. 1014-1022 9 p.

Research output: Contribution to journalArticle

Pyrimidine Dimers
Lyases
Modulation
Enzymes
Mutagenesis
12 Citations

Role of high-fidelity Escherichia coli DNA polymerase I in replication bypass of a deoxyadenosine DNA-peptide cross-link

Yamanaka, K., Minko, I. G., Finkel, S. E., Goodman, M. F. & Lloyd, R. S., Aug 2011, In : Journal of Bacteriology. 193, 15, p. 3815-3821 7 p.

Research output: Contribution to journalArticle

DNA Polymerase I
Escherichia coli
Peptides
DNA
Oligodeoxyribonucleotides
13 Citations

TAT-mediated delivery of a DNA repair enzyme to skin cells rapidly initiates repair of UV-induced DNA damage

Johnson, J. L., Lowell, B. C., Ryabinina, O. P., Lloyd, R. S. & McCullough, A. K., Mar 2011, In : Journal of Investigative Dermatology. 131, 3, p. 753-761 9 p.

Research output: Contribution to journalArticle

DNA Repair Enzymes
Trans-Activators
DNA Repair
DNA Damage
Skin
20 Citations

The base excision repair pathway is required for efficient lentivirus integration

Yoder, K. E., Espeseth, A., Wang, X. H., Fang, Q., Russo, M. T., Lloyd, R. S., Hazuda, D., Sobol, R. W. & Fishel, R., 2011, In : PLoS One. 6, 3, e17862.

Research output: Contribution to journalArticle

Lentivirus
DNA repair
DNA Repair
Repair
HIV infections
19 Citations

Variable penetrance of metabolic phenotypes and development of high-fat diet-induced adiposity in NEIL1-deficient mice.

Sampath, H., Batra, A. K., Vartanian, V., Carmical, J. R., Prusak, D., King, I. B., Lowell, B., Earley, L. F., Wood, T. G., Marks, D. L., McCullough, A. K. & R Stephen, L., Apr 2011, In : American journal of physiology. Endocrinology and metabolism. 300, 4

Research output: Contribution to journalArticle

Penetrance
Adiposity
High Fat Diet
Phenotype
Oxidative Stress
5 Citations

γ-Hydroxy-1, N 2-propano-2′-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage

Huang, H., Wang, H., Voehler, M. W., Kozekova, A., Rizzo, C. J., McCullough, A. K., Lloyd, R. S. & Stone, M. P., Jul 18 2011, In : Chemical Research in Toxicology. 24, 7, p. 1123-1133 11 p.

Research output: Contribution to journalArticle

Deoxyguanosine
DNA Adducts
Amines
Peptides
DNA
2010
27 Citations

DNA cross-link induced by trans-4-hydroxynonenal

Huang, H., Kozekov, I. D., Kozekova, A., Wang, H., Lloyd, R. S., Rizzo, C. J. & Stone, M. P., Jul 2010, In : Environmental and Molecular Mutagenesis. 51, 6, p. 625-634 10 p.

Research output: Contribution to journalArticle

Aldehydes
DNA
2-butenal
Omega-6 Fatty Acids
Acrolein
39 Citations

Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5′R)- and (5′S)-8,5′-Cyclo-2′- deoxyadenosines

Jaruga, P., Xiao, Y., Vartanian, V., Lloyd, R. S. & Dizdaroglu, M., Feb 16 2010, In : Biochemistry. 49, 6, p. 1053-1055 3 p.

Research output: Contribution to journalArticle

DNA Repair Enzymes
DNA Repair
Repair
Nucleotides
Liver

Interstrand DNA Cross-Linking 1, N 2-Deoxyguanosine Adducts Derived from α,β-Unsaturated Aldehydes: Structure-Function Relationships

Stone, M. P., Huang, H., Cho, Y. J., Kim, H. Y., Kozekov, I. D., Kozekova, A., Wang, H., Harris, T. M., Rizzo, C. J., Minko, I. G. & Lloyd, R. S., Oct 11 2010, The Chemical Biology of DNA Damage. Wiley-VCH, p. 201-216 16 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2-butenal
Acrolein
Stereochemistry
Deoxyguanosine
DNA Adducts
11 Citations

Minor groove orientation of the KWKK peptide tethered via the N-terminal amine to the acrolein-derived 1, N 2-γ- hydroxypropanodeoxyguanosine lesion with a trimethylene linkage

Huang, H., Kozekov, I. D., Kozekova, A., Rizzo, C. J., McCullough, A. K., Lloyd, R. S. & Stone, M. P., Jul 27 2010, In : Biochemistry. 49, 29, p. 6155-6164 10 p.

Research output: Contribution to journalArticle

Acrolein
Amines
Peptides
DNA
Lysine
20 Citations

Modulation of UvrD helicase activity by covalent DNA-protein cross-links

Kumari, A., Minko, I. G., Smith, R. L., Lloyd, R. S. & McCullough, A. K., Jul 9 2010, In : Journal of Biological Chemistry. 285, 28, p. 21313-21322 10 p.

Research output: Contribution to journalArticle

Modulation
DNA
Proteins
DNA Replication
link protein
40 Citations

Novel enzymatic function of DNA Polymerase v in translesion DNA synthesis past major groove DNA-peptide and DNA-DNA cross-links

Yamanaka, K., Minko, I. G., Takata, K. I., Kolbanovskiy, A., Kozekov, I. D., Wood, R. D., Rizzo, C. J. & Lloyd, R. S., Mar 15 2010, In : Chemical Research in Toxicology. 23, 3, p. 689-695 7 p.

Research output: Contribution to journalArticle

DNA-Directed DNA Polymerase
Peptides
DNA
Nucleotides
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
2009
118 Citations

Chemistry and biology of DNA containing 1,N2-deoxyguanosine adducts of the α,β-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal

Minko, I. G., Kozekov, I. D., Harris, T. M., Rizzo, C. J., Lloyd, R. S. & Stone, M. P., May 18 2009, In : Chemical Research in Toxicology. 22, 5, p. 759-778 20 p.

Research output: Contribution to journalArticle

2-butenal
Acrolein
Deoxyguanosine
Aldehydes
DNA
11 Citations

Conformational interconversion of the trans-4-hydroxynonenal-derived (6S,8R,11S) l,N 2-deoxyguanosine adduct when mismatched with deoxyadenosine in DNA

Huang, H., Wang, H., Lloyd, R. S., Rizzo, C. J. & Stone, M. P., Jan 2009, In : Chemical Research in Toxicology. 22, 1, p. 187-200 14 p.

Research output: Contribution to journalArticle

Deoxyguanosine
Base Pairing
Conformations
DNA
Structural analysis
15 Citations

Deficiency of the oxidative damage-specific DNA glycosylase NEIL1 leads to reduced germinal center B cell expansion

Mori, H., Ouchida, R., Hijikata, A., Kitamura, H., Ohara, O., Li, Y., Gao, X., Yasui, A., Lloyd, R. S. & Wang, J. Y., Nov 2 2009, In : DNA Repair. 8, 11, p. 1328-1332 5 p.

Research output: Contribution to journalArticle

DNA Glycosylases
Germinal Center
B-Lymphocytes
Cells
Immunoglobulin Genes
68 Citations

Targeted deletion of the genes encoding NTH1 and NEIL1 DNA N-glycosylases reveals the existence of novel carcinogenic oxidative damage to DNA

Chan, M. K., Ocampo-Hafalla, M. T., Vartanian, V., Jaruga, P., Kirkali, G., Koenig, K. L., Brown, S., Lloyd, R. S., Dizdaroglu, M. & Teebor, G. W., Jul 4 2009, In : DNA Repair. 8, 7, p. 786-794 9 p.

Research output: Contribution to journalArticle

DNA Glycosylases
Gene encoding
Gene Deletion
DNA Damage
Tumors
2008
102 Citations

Interstrand DNA cross-links induced by α,β-unsaturated aldehydes derived from lipid peroxidation and environmental sources

Stonez, M. P., Cho, Y. J., Huang, H., Kim, H. Y., Kozekov, I. D., Kozekova, A., Wang, H., Minko, I. G., Lloyd, R. S., Harris, T. M. & Rizzo, C. J., Jul 2008, In : Accounts of Chemical Research. 41, 7, p. 793-804 12 p.

Research output: Contribution to journalArticle

2-butenal
Aldehydes
Lipids
DNA
Acrolein
40 Citations

Mutagenic potential of DNA-peptide crosslinks mediated by acrolein-derived DNA adducts

Minko, I. G., Kozekov, I. D., Kozekova, A., Harris, T. M., Rizzo, C. J. & Lloyd, R. S., Jan 1 2008, In : Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 637, 1-2, p. 161-172 12 p.

Research output: Contribution to journalArticle

Acrolein
DNA Adducts
Peptides
DNA
Deoxyguanosine
40 Citations

Replication bypass of interstrand cross-link intermediates by Escherichia coli DNA polymerase IV

Kumari, A., Minko, I. G., Harbut, M. B., Finkel, S. E., Goodman, M. F. & Lloyd, R. S., Oct 10 2008, In : Journal of Biological Chemistry. 283, 41, p. 27433-27437 5 p.

Research output: Contribution to journalArticle

DNA Polymerase beta
Escherichia coli
DNA
Repair
Nucleotides
44 Citations

Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family

Minko, I. G., Yamanaka, K., Kozekov, I. D., Kozekova, A., Indiani, C., O'Donnell, M. E., Jiang, Q., Goodman, M. F., Rizzo, C. J. & Lloyd, R. S., Oct 2008, In : Chemical Research in Toxicology. 21, 10, p. 1983-1990 8 p.

Research output: Contribution to journalArticle

Acrolein
DNA-Directed DNA Polymerase
Peptides
DNA
Escherichia coli
99 Citations

Role for DNA polymerase κ in the processing of N2-N 2-guanine interstrand cross-links

Minko, I. G., Harbut, M. B., Kozekov, I. D., Kozekova, A., Jakobs, P. M., Olson, S. B., Moses, R. E., Harris, T. M., Rizzo, C. J. & Lloyd, R. S., Jun 20 2008, In : Journal of Biological Chemistry. 283, 25, p. 17075-17082 8 p.

Research output: Contribution to journalArticle

Guanine
DNA-Directed DNA Polymerase
Processing
Oligodeoxyribonucleotides
Mitomycin
15 Citations

The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N 2-2′-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5′-CpG-3′ sequence

Huang, H., Wang, H., Qi, N., Lloyd, R. S., Rizzo, C. J. & Stone, M. P., Nov 4 2008, In : Biochemistry. 47, 44, p. 11457-11472 16 p.

Research output: Contribution to journalArticle

Stereochemistry
Deoxyguanosine
Aldehydes
Stereoisomerism
Conformations