• 1092 Citations
  • 18 h-Index
1976 …2014
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Research Output 1979 2014

  • 1092 Citations
  • 18 h-Index
  • 43 Article
  • 2 Chapter
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Article
2014
13 Citations (Scopus)

Mechanism of protection by soluble epoxide hydrolase inhibition in type 2 diabetic stroke

Zuloaga, K. L., Krasnow, S., Zhu, X., Zhang, W., Jouihan, S. A., Shangraw, R., Alkayed, N. & Marks, D., May 13 2014, In : PLoS One. 9, 5, e97529.

Research output: Contribution to journalArticle

epoxide hydrolase
Epoxide Hydrolases
stroke
Stroke
mice
2013
22 Citations (Scopus)

Role of soluble epoxide hydrolase in exacerbation of stroke by streptozotocin-induced type 1 diabetes mellitus

Jouihan, S. A., Zuloaga, K. L., Zhang, W., Shangraw, R., Krasnow, S., Marks, D. & Alkayed, N., Oct 2013, In : Journal of Cerebral Blood Flow and Metabolism. 33, 10, p. 1650-1656 7 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Streptozocin
Type 1 Diabetes Mellitus
Stroke
Hyperglycemia
2008
4 Citations (Scopus)

Dichloroacetate stabilizes the intraoperative acid-base balance during liver transplantation

Shangraw, R., Lohan-Mannion, D., Hayes, A., Moriarty, R. M., Fu, R. R. & Robinson, S., Jul 2008, In : Liver Transplantation. 14, 7, p. 989-998 10 p.

Research output: Contribution to journalArticle

Acid-Base Equilibrium
Liver Transplantation
Length of Stay
Lactic Acidosis
Lactic Acid
2007
20 Citations (Scopus)

Managing intergenerational differences in academic anesthesiology

Shangraw, R. & Whitten, C. W., Dec 2007, In : Current Opinion in Anaesthesiology. 20, 6, p. 558-563 6 p.

Research output: Contribution to journalArticle

Anesthesiology
Workplace
Life Style
Mentors
Medical Students
80 Citations (Scopus)

Volume replacement therapy during major orthopedic surgery using Voluven® (Hydroxyethyl starch 130/0.4) or hetastarch

Gandhi, S. D., Weiskopf, R. B., Jungheinrich, C., Koorn, R., Miller, D., Shangraw, R., Prough, D. S., Baus, D., Bepperling, F. & Warltier, D. C., Jun 2007, In : Anesthesiology. 106, 6, p. 1120-1127 8 p.

Research output: Contribution to journalArticle

Hydroxyethyl Starch Derivatives
Orthopedics
Colloids
Therapeutics
Factor VIII
2006
13 Citations (Scopus)
Dichloroacetic Acid
Pharmacokinetics
Isotopes
Drinking Water
Biological Availability
28 Citations (Scopus)

Metabolic issues in liver transplantation

Shangraw, R., Sep 2006, In : International Anesthesiology Clinics. 44, 3, p. 1-20 20 p.

Research output: Contribution to journalArticle

Acid-Base Equilibrium
Citric Acid
Liver Cirrhosis
Liver Transplantation
Magnesium
2004
13 Citations (Scopus)

Mechanism of dichloroacetate-induced hypolactatemia in humans with or without cirrhosis

Shangraw, R. & Jahoor, F., Aug 2004, In : Metabolism: Clinical and Experimental. 53, 8, p. 1087-1094 8 p.

Research output: Contribution to journalArticle

Pyruvic Acid
Fibrosis
Lactic Acid
Alanine
Glycolysis
2000
12 Citations (Scopus)
Lipolysis
Liver Transplantation
Glycerol
Fibrosis
Palmitates
6 Citations (Scopus)

Massive airway edema after azathioprine

Jungling, A. S. & Shangraw, R., Mar 2000, In : Anesthesiology. 92, 3, p. 888-890 3 p.

Research output: Contribution to journalArticle

Tongue Diseases
Polycystic Kidney Diseases
Azathioprine
Graft Rejection
Airway Obstruction
1999
29 Citations (Scopus)
Liver Transplantation
Urea
Liver Diseases
Alkalosis
Acids
9 Citations (Scopus)

Pharmacokinetics and pharmacodynamics of dichloroacetate in patients with cirrhosis

Shangraw, R. & Fisher, D. M., 1999, In : Clinical Pharmacology and Therapeutics. 66, 4, p. 380-390 11 p.

Research output: Contribution to journalArticle

Fibrosis
Pharmacokinetics
Glucose
Hypoglycemia
Lactic Acid
1998
20 Citations (Scopus)
Pyruvic Acid
Human Activities
Oxidoreductases
Fibrosis
Transplantation
1997
8 Citations (Scopus)

Metabolism during liver transplantation: The effect of dichloroacetate

Shangraw, R. & Robinson, S., Oct 1997, In : Anesthesia and Analgesia. 85, 4, p. 746-752 7 p.

Research output: Contribution to journalArticle

Liver Transplantation
Liver
Pyruvic Acid
Transplants
Oxidoreductases
1996
7 Citations (Scopus)

Dichloroacetate reduces plasma lactate levels but does not reduce infarct size in rabbit myocardium

Haessler, R., Davis, R. F., Wolff, R. A., Kuzume, K., Shangraw, R. & Van Winkle, D. M., 1996, In : Shock. 5, 1, p. 66-71 6 p.

Research output: Contribution to journalArticle

Lactic Acid
Myocardium
Rabbits
Myocardial Reperfusion
Coronary Occlusion
25 Citations (Scopus)

Glucose and potassium metabolic responses to insulin during liver transplantation

Shangraw, R. & Hexem, J. G., 1996, In : Liver Transplantation and Surgery. 2, 6, p. 443-454 12 p.

Research output: Contribution to journalArticle

Liver Transplantation
Potassium
Insulin
Glucose
Hyperglycemia

Kinetics of palmitate metabolism in patients before and after liver transplantation

Shangraw, R., Jahoor, F., Rabkin, J. & Hayes, A., 1996, In : FASEB Journal. 10, 3

Research output: Contribution to journalArticle

liver transplant
Enzyme kinetics
Palmitates
palmitates
Nonesterified Fatty Acids
16 Citations (Scopus)

Pharmacokinetics of dichloroacetate in patients undergoing liver transplantation

Shangraw, R. & Fisher, D. M., Apr 1996, In : Anesthesiology. 84, 4, p. 851-858 8 p.

Research output: Contribution to journalArticle

Liver Transplantation
Pharmacokinetics
Liver
End Stage Liver Disease
Lactic Acidosis
21 Citations (Scopus)

Pyruvate dehydrogenase inactivity is not responsible for sepsis-induced insulin resistance

Shangraw, R., Jahoor, F., Wolfe, R. R. & Lang, C. H., Apr 1996, In : Critical Care Medicine. 24, 4, p. 566-574 9 p.

Research output: Contribution to journalArticle

Pyruvic Acid
Insulin Resistance
Sepsis
Oxidoreductases
Glucose
1995
5 Citations (Scopus)

Should acidosis during liver transplantation be treated? [4]

Bogdonoff, D. L., Spiekermann, B. F. & Shangraw, R., 1995, In : Anesthesiology. 82, 6, p. 1540-1541 2 p.

Research output: Contribution to journalArticle

Lactic Acidosis
Sodium Bicarbonate
Acidosis
Liver Transplantation
1994
40 Citations (Scopus)

Amelioration of lactic acidosis with dichloroacetate during liver transplantation in humans

Shangraw, R., Winter, R., Hromco, J., Robinson, S. & Gallaher, E. J., 1994, In : Anesthesiology. 81, 5, p. 1127-1138 12 p.

Research output: Contribution to journalArticle

Lactic Acidosis
Liver Transplantation
Lactic Acid
Hypernatremia
Acidosis
1 Citation (Scopus)

Oxygen consumption and oxygen delivery

Shangraw, R., 1994, In : Seminars in Anesthesia. 13, 3, p. 265-275 11 p.

Research output: Contribution to journalArticle

Indirect Calorimetry
Oxygen Consumption
Oxygen
Critical Illness
Energy Metabolism
1993
1 Citation (Scopus)

Glucose-insulin-potassium regimes during cardiac surgery [8]

Shangraw, R. & Boldt, J., 1993, In : Anesthesia and Analgesia. 77, 4, p. 869-870 2 p.

Research output: Contribution to journalArticle

Cardiac Surgical Procedures
Thoracic Surgery
Potassium
Insulin
Glucose
1991
36 Citations (Scopus)

Lipolytic response to metabolic stress in critically ill patients

Klein, S., Peters, E. J., Shangraw, R. & Wolfe, R. R., 1991, In : Critical Care Medicine. 19, 6, p. 776-779 4 p.

Research output: Contribution to journalArticle

Physiological Stress
Critical Illness
Fatty Acids
Glycerol
Palmitic Acid
1990
71 Citations (Scopus)

Effect of dietary protein on bed-rest-related changes in whole-body-protein synthesis

Stuart, C. A., Shangraw, R., Peters, E. J. & Wolfe, R. R., Sep 1990, In : American Journal of Clinical Nutrition. 52, 3, p. 509-514 6 p.

Research output: Contribution to journalArticle

Bed Rest
Dietary Proteins
body protein
Leucine
leucine
1989
151 Citations (Scopus)

Differentiation between septic and postburn insulin resistance

Shangraw, R., Jahoor, F., Miyoshi, H., Neff, W. A., Stuart, C. A., Herndon, D. N. & Wolfe, R. R., 1989, In : Metabolism. 38, 10, p. 983-989 7 p.

Research output: Contribution to journalArticle

Insulin Resistance
Insulin
Glucose
Potassium
Sepsis
80 Citations (Scopus)

Role of insulin and glucose oxidation in mediating the protein catabolism of burns and sepsis

Jahoor, F., Shangraw, R., Miyoshi, H., Wallfish, H., Herndon, D. N. & Wolfe, R. R., 1989, In : American Journal of Physiology - Endocrinology and Metabolism. 257, 3

Research output: Contribution to journalArticle

Burns
Leucine
Sepsis
Clamping devices
Urea
1988
180 Citations (Scopus)

Bed-rest-induced insulin resistance occurs primarily in muscle

Stuart, C. A., Shangraw, R., Prince, M. J., Peters, E. J. & Wolfe, R. R., 1988, In : Metabolism. 37, 8, p. 802-806 5 p.

Research output: Contribution to journalArticle

Bed Rest
Insulin Resistance
Insulin
Muscles
Glucose
80 Citations (Scopus)

Insulin responsiveness of protein metabolism in vivo following bedrest in humans

Shangraw, R., Stuart, C. A., Prince, M. J., Peters, E. J. & Wolfe, R. R., 1988, In : American Journal of Physiology - Endocrinology and Metabolism. 255, 4

Research output: Contribution to journalArticle

Bed Rest
Metabolism
Leucine
Insulin
Proteins
1985

Attention deficit disorder, amphetamine, and pregnancy

Shangraw, R., Seminer, S. J. & Zarr, M. L., 1985, In : Biological Psychiatry. 20, 8, p. 926-927 2 p.

Research output: Contribution to journalArticle

Prenatal Exposure Delayed Effects
Dextroamphetamine
Amphetamine
Attention Deficit Disorder with Hyperactivity
Pregnancy
1984
19 Citations (Scopus)

Altered protein kinetics in vivo after single-limb burn injury

Shangraw, R. & Turinsky, J., 1984, In : Biochemical Journal. 223, 3, p. 747-753 7 p.

Research output: Contribution to journalArticle

Extremities
Skeletal Muscle
Kinetics
Wounds and Injuries
Muscle

Evaluation of postburn protein turnover by skeletal muscle in vivo

Shangraw, R. & Turinsky, J., 1984, In : Federation Proceedings. 43, 3

Research output: Contribution to journalArticle

Skeletal Muscle
Proteins
1982
18 Citations (Scopus)

Effect of disuse and thermal injury on protein turnover in skeletal muscle

Shangraw, R. & Turinsky, J., 1982, In : Journal of Surgical Research. 33, 4, p. 345-355 11 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Hot Temperature
Muscles
Wounds and Injuries
Extremities
1981
4 Citations (Scopus)
Ketone Bodies
Muscle
Amino Acids
Glucose
Muscles
1 Citation (Scopus)

Chronic alterations in energy metabolism in the burned rat

Shangraw, R. & Turinsky, J., 1981, In : Burns. 7, 4, p. 261-266 6 p.

Research output: Contribution to journalArticle

Energy Metabolism
Wound Healing
Animal Models
Body Weight
Food

Differential actions of branched-chain amino acids on proteolysis by muscle from burned rats

Shangraw, R. & Turinsky, J., 1981, In : Physiologist. 24, 4

Research output: Contribution to journalArticle

Proteolysis
Branched Chain Amino Acids
Muscle
Rats
17 Citations (Scopus)

Local response of muscle to burns: relationship of glycolysis and amino acid release.

Shangraw, R. & Turinsky, J., May 1981, In : Journal of Parenteral and Enteral Nutrition. 5, 3, p. 193-199 7 p.

Research output: Contribution to journalArticle

Lactates
Iodoacetic Acid
Iodoacetates
Glycolysis
Muscular Diseases
1980
1 Citation (Scopus)

Effects of leucine on thermally-injured skeletal muscle

Shangraw, R. & Turinsky, J., 1980, In : Physiologist. 23, 4

Research output: Contribution to journalArticle

Leucine
Muscle
4 Citations (Scopus)

Energy metabolism of vascular smooth muscle and circulating vasoactive substances in hemorrhagic shock in the dog

Turinsky, J., Loegering, D. J., Patterson, S. A., Shangraw, R., Lipinski, T. L. & Wong, P. Y., 1980, In : Circulatory Shock. 7, 4, p. 361-372 12 p.

Research output: Contribution to journalArticle

Hemorrhagic Shock
Vascular Smooth Muscle
Energy Metabolism
Dogs
Hypotension
Iodoacetates
Glutamine
Alanine
Glutamic Acid
Adenosine Triphosphate

Valine and isoleucine inhibit glucose uptake and alanine release by thermally injured muscle

Turinsky, J. & Shangraw, R., 1980, In : Physiologist. 23, 4

Research output: Contribution to journalArticle

Isoleucine
Valine
Alanine
Muscle
Glucose
1979
15 Citations (Scopus)

Biphasic alterations in glucose metabolism by soleus muscle from the burned limb.

Turinsky, J. & Shangraw, R., 1979, In : Advances in shock research. 2, p. 23-30 8 p.

Research output: Contribution to journalArticle

Skeletal Muscle
Extremities
Glucose
Temperature
Lactic Acid
22 Citations (Scopus)

Local effect of burn injury on glucose and amino acid metabolism by skeletal muscle.

Shangraw, R. & Turinsky, J., Sep 1979, In : Journal of Parenteral and Enteral Nutrition. 3, 5, p. 323-327 5 p.

Research output: Contribution to journalArticle

burns (injuries)
amino acid metabolism
skeletal muscle
Skeletal Muscle
Amino Acids