Rebecca Spain

Assistant Professor

  • 784 Citations
  • 16 h-Index
20092020

Research output per year

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Research Output

2020

Conducting dietary intervention trials in people with multiple sclerosis: Lessons learned and a path forward

Fitzgerald, K. C., Sand, I. K., Senders, A., Spain, R., Giesser, B., Sullivan, P., Baer, D. J., LaRocca, N., Zackowski, K. & Mowry, E. M., Jan 2020, In : Multiple sclerosis and related disorders. 37, 101478.

Research output: Contribution to journalReview article

2019

Lipoic Acid and Other Antioxidants as Therapies for Multiple Sclerosis

Waslo, C., Bourdette, D., Gray, N., Wright, K. & Spain, R., Jun 1 2019, In : Current Treatment Options in Neurology. 21, 6, 26.

Research output: Contribution to journalReview article

8 Scopus citations
2018
2 Scopus citations

Effects of lipoic acid on walking performance, gait, and balance in secondary progressive multiple sclerosis

Loy, B. D., Fling, B., Horak, F., Bourdette, D. & Spain, R., Dec 1 2018, In : Complementary Therapies in Medicine. 41, p. 169-174 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Gender Inequities in the Multiple Sclerosis Community: A Call for Action

International Women in MS, Dec 1 2018, In : Annals of Neurology. 84, 6, p. 958-959 2 p.

Research output: Contribution to journalLetter

Open Access
6 Scopus citations

Myelin Oligodendrocyte Glycoprotein Antibody-Associated Demyelination Comorbid with Leber Hereditary Optic Neuropathy

Bittner, F., Falardeau, J. & Spain, R., Jan 1 2018, (Accepted/In press) In : JAMA Neurology.

Research output: Contribution to journalArticle

21 Scopus citations
2017
3 Scopus citations

Lipoic acid in secondary progressive MS

Spain, R., Powers, K., Murchison, C., Heriza, E., Winges, K., Yadav, V., Cameron, M., Kim, E., Horak, F., Simon, J. & Bourdette, D., 2017, In : Neurology: Neuroimmunology and NeuroInflammation. 4, 5, 374.

Research output: Contribution to journalArticle

34 Scopus citations

Lipoic acid pharmacokinetics at baseline and 1 year in secondary progressive MS

Bittner, F., Murchison, C., Koop, D., Bourdette, D. & Spain, R., 2017, In : Neurology: Neuroimmunology and NeuroInflammation. 4, 5, 380.

Research output: Contribution to journalShort survey

5 Scopus citations

Lipoic Acid Stimulates cAMP Production in Healthy Control and Secondary Progressive MS Subjects

Fiedler, S. E., Yadav, V., Kerns, A. R., Tsang, C., Markwardt, S., Kim, E., Spain, R., Bourdette, D. & Salinthone, S., Nov 15 2017, (Accepted/In press) In : Molecular Neurobiology. p. 1-13 13 p.

Research output: Contribution to journalArticle

3 Scopus citations
4 Scopus citations
2016

Characterization of Compensatory Stepping in People with Multiple Sclerosis

Peterson, D. S., Huisinga, J. M., Spain, R. I. & Horak, F. B., Apr 1 2016, In : Archives of Physical Medicine and Rehabilitation. 97, 4, p. 513-521 9 p.

Research output: Contribution to journalArticle

10 Scopus citations

Dietary supplements and other alternative substances for the treatment of multiple sclerosis

Senders, A., Spain, R. & Yadav, V., Apr 19 2016, Nutraceuticals and Health: Review of Human Evidence. CRC Press, p. 327-351 25 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Longitudinal associations between brain structural changes and fatigue in early MS

Nourbakhsh, B., Azevedo, C., Nunan-Saah, J., Maghzi, A. H., Spain, R., Pelletier, D. & Waubant, E., Jan 1 2016, In : Multiple Sclerosis and Related Disorders. 5, p. 29-33 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Longitudinal associations between MRI and cognitive changes in very early MS

Nourbakhsh, B., Nunan-Saah, J., Maghzi, A. H., Julian, L. J., Spain, R., Jin, C., Lazar, A., Pelletier, D. & Waubant, E., Jan 1 2016, In : Multiple Sclerosis and Related Disorders. 5, p. 47-52 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Low-fat, plant-based diet in multiple sclerosis: A randomized controlled trial

Yadav, V., Marracci, G., Kim, E., Spain, R., Cameron, M., Overs, S., Riddehough, A., Li, D. K. B., McDougall, J., Lovera, J., Murchison, C. & Bourdette, D., Sep 1 2016, In : Multiple sclerosis and related disorders. 9, p. 80-90 11 p.

Research output: Contribution to journalArticle

31 Scopus citations
4 Scopus citations

Subcortical grey matter volumes predict subsequent walking function in early multiple sclerosis

Nourbakhsh, B., Azevedo, C., Maghzi, A. H., Spain, R., Pelletier, D. & Waubant, E., Jul 15 2016, In : Journal of the Neurological Sciences. 366, p. 229-233 5 p.

Research output: Contribution to journalArticle

4 Scopus citations

The contemporary spectrum of multiple sclerosis misdiagnosis

Solomon, A. J., Bourdette, D. N., Cross, A. H., Applebee, A., Skidd, P. M., Howard, D. B., Spain, R. I., Cameron, M. H., Kim, E., Mass, M. K., Yadav, V., Whitham, R. H., Longbrake, E. E., Naismith, R. T., Wu, G. F., Parks, B. J., Wingerchuk, D. M., Rabin, B. L., Toledano, M., Tobin, W. O. & 4 others, Kantarci, O. H., Carter, J. L., Keegan, B. M. & Weinshenker, B. G., Sep 27 2016, In : Neurology. 87, 13, p. 1393-1399 7 p.

Research output: Contribution to journalArticle

87 Scopus citations
2015

Retinal axonal loss in very early stages of multiple sclerosis

Maghzi, A. H., Graves, J., Revirajan, N., Spain, R., Liu, S., Mcculloch, C. E., Pelletier, D., Green, A. J. & Waubant, E., Jul 1 2015, In : European Journal of Neurology. 22, 7, p. 1138-1141 4 p.

Research output: Contribution to journalArticle

8 Scopus citations
2014

A randomized controlled phase II trial of riluzole in early multiple sclerosis

Waubant, E., Maghzi, A. H., Revirajan, N., Spain, R., Julian, L., Mowry, E. M., Marcus, J., Liu, S., Jin, C., Green, A., McCulloch, C. E. & Pelletier, D., May 2014, In : Annals of Clinical and Translational Neurology. 1, 5, p. 340-347 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
26 Scopus citations

Magnetic resonance imaging correlates of clinical outcomes in early multiple sclerosis

Maghzi, A. H., Revirajan, N., Julian, L. J., Spain, R., Mowry, E. M., Liu, S., Jin, C., Green, A. J., McCulloch, C. E., Pelletier, D. & Waubant, E., Jan 1 2014, In : Multiple sclerosis and related disorders. 3, 6, p. 720-727 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Optical coherence tomography angiography of optic nerve head and parafovea in multiple sclerosis

Wang, X., Jia, Y., Spain, R., Potsaid, B., Liu, J. J., Baumann, B., Hornegger, J., Fujimoto, J. G., Wu, Q. & Huang, D., Oct 1 2014, In : British Journal of Ophthalmology. 98, 10, p. 1368-1373 6 p.

Research output: Contribution to journalArticle

109 Scopus citations

Postural response latencies are related to balance control during standing and walking in patients with multiple sclerosis

Huisinga, J. M., St George, R. J., Spain, R., Overs, S. & Horak, F. B., Jul 2014, In : Archives of Physical Medicine and Rehabilitation. 95, 7, p. 1390-1397 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
2012

Body-worn motion sensors detect balance and gait deficits in people with multiple sclerosis who have normal walking speed

Spain, R. I., St. George, R. J., Salarian, A., Mancini, M., Wagner, J. M., Horak, F. B. & Bourdette, D., Apr 1 2012, In : Gait and Posture. 35, 4, p. 573-578 6 p.

Research output: Contribution to journalArticle

143 Scopus citations

Mind-body medicine for multiple sclerosis: A systematic review

Senders, A., Wahbeh, H., Spain, R. & Shinto, L., Dec 26 2012, In : Autoimmune Diseases. 1, 1, 567324.

Research output: Contribution to journalReview article

30 Scopus citations
2011

Inflammatory neurological disease in patients treated with tumor necrosis factor alpha inhibitors

Solomon, A. J., Spain, R. I., Kruer, M. C. & Bourdette, D., Dec 2011, In : Multiple Sclerosis Journal. 17, 12, p. 1472-1487 16 p.

Research output: Contribution to journalArticle

62 Scopus citations

The radiologically isolated syndrome: Look (again) before you treat

Spain, R. & Bourdette, D., Oct 1 2011, In : Current neurology and neuroscience reports. 11, 5, p. 498-506 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
2009

Recent developments in multiple sclerosis therapeutics

Spain, R. I., Cameron, M. H. & Bourdette, D., Dec 7 2009, In : BMC Medicine. 7, 74.

Research output: Contribution to journalShort survey

21 Scopus citations
19 Scopus citations

When metals compete: A case of copper-deficiency myeloneuropathy and anemia

Spain, R. I., Leist, T. P. & De Sousa, E. A., Feb 16 2009, In : Nature Clinical Practice Neurology. 5, 2, p. 106-111 6 p.

Research output: Contribution to journalArticle

25 Scopus citations