Randall (Randy) Woltjer

Assistant Professor

  • 5284 Citations
  • 38 h-Index
1990 …2020

Research Output 1992 2018

  • 5284 Citations
  • 38 h-Index
  • 113 Article
  • 4 Chapter
  • 2 Review article
  • 1 Letter
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Article
2018

Augmented frontal cortex diacylglycerol levels in Parkinson’s disease and Lewy Body Disease

Wood, P. L., Tippireddy, S., Feriante, J. & Woltjer, R. L. Mar 1 2018 In : PLoS ONE. 13, 3, e0191815

Research output: Contribution to journalArticle

Lewy Body Disease
Diglycerides
Frontal Lobe
diacylglycerols
Parkinson Disease

Silent somatotroph pituitary adenomas: an update

Langlois, F., Woltjer, R., Cetas, J. S. & Fleseriu, M. Jan 5 2018 (Accepted/In press) In : Pituitary. p. 1-9 9 p.

Research output: Contribution to journalArticle

Growth Hormone-Secreting Pituitary Adenoma
Neuroendocrine Tumors
Pituitary Neoplasms
Acromegaly
Neoplasms
2017

Acetyl-4′-phosphopantetheine is stable in serum and prevents phenotypes induced by pantothenate kinase deficiency

Di Meo, I. , Colombelli, C. , Srinivasan, B. , De Villiers, M. , Hamada, J. , Jeong, S. Y. , Fox, R. , Woltjer, R. L. , Tepper, P. G. , Lahaye, L. L. , Rizzetto, E. , Harrs, C. H. , De Boer, T. , Van Der Zwaag, M. , Jenko, B. , Čusak, A. , Pahor, J. , Kosec, G. , Grzeschik, N. A. , Hayflick, S. J. & 2 others Tiranti, V. & Sibon, O. C. M. Dec 1 2017 In : Scientific Reports. 7, 1, 11260

Research output: Contribution to journalArticle

Coenzyme A
Phenotype
Pantothenate Kinase-Associated Neurodegeneration
Serum
Pantothenic Acid
3 Citations

Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples

Brenowitz, W. D., Keene, C. D., Hawes, S. E., Hubbard, R. A., Longstreth, W. T., Woltjer, R. L., Crane, P. K., Larson, E. B. & Kukull, W. A. May 1 2017 In : Neurobiology of Aging. 53, p. 83-92 10 p.

Research output: Contribution to journalArticle

Cerebrovascular Trauma
Lewy Body Disease
Alzheimer Disease
Dementia
Population
19 Citations

Association of perivascular localization of aquaporin-4 with cognition and Alzheimer disease in aging brains

Zeppenfeld, D. M., Simon, M., Haswell, J. D., D'Abreo, D., Murchison, C., Quinn, J. F., Grafe, M. R., Woltjer, R. L., Kaye, J. & Iliff, J. J. Jan 1 2017 In : JAMA Neurology. 74, 1, p. 91-99 9 p.

Research output: Contribution to journalArticle

Aquaporin 4
Cognition
Alzheimer Disease
Brain
Amyloid

Enhancing the cytotoxicity of chemoradiation with radiation-guided delivery of anti-MGMT morpholino oligonucleotides in non-methylated solid tumors

Ambady, P., Wu, Y. J., Walker, J. M., Kersch, C., Pagel, M. A., Woltjer, R. L., Fu, R., Muldoon, L. L. & Neuwelt, E. A. Aug 1 2017 In : Cancer Gene Therapy. 24, 8, p. 348-357 10 p.

Research output: Contribution to journalArticle

Morpholinos
Methyltransferases
Radiation
DNA
temozolomide
3 Citations

Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's compared to dementia with Lewy bodies

Tagliafierro, L., Glenn, O. C., Zamora, M. E., Beach, T. G., Woltjer, R. L., Lutz, M. W. & Chiba-Falek, O. 2017 (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Lewy Body Disease
alpha-Synuclein
3' Untranslated Regions
MicroRNAs
Parkinson Disease

Interpreting gene expression effects of disease-associated variants: A lesson from SNCA rs356168

Glenn, O. C., Tagliafierro, L., Beach, T. G., Woltjer, R. L. & Chiba-Falek, O. Sep 20 2017 In : Frontiers in Genetics. 8, SEP, 133

Research output: Contribution to journalArticle

Alleles
Frontal Lobe
Gene Expression
Messenger RNA
Single Nucleotide Polymorphism

Mixed neuropathologies and associations with domain-specific cognitive decline

Brenowitz, W. D., Hubbard, R. A., Keene, C. D., Hawes, S. E., Longstreth, W. T., Woltjer, R. L. & Kukull, W. A. Oct 24 2017 In : Neurology. 89, 17, p. 1773-1781 9 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Cerebrovascular Trauma
Lewy Body Disease
Executive Function
Language
37 Citations

Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis

Irwin, D. J. , Grossman, M. , Weintraub, D. , Hurtig, H. I. , Duda, J. E. , Xie, S. X. , Lee, E. B. , Van Deerlin, V. M. , Lopez, O. L. , Kofler, J. K. , Nelson, P. T. , Jicha, G. A. , Woltjer, R. , Quinn, J. F. , Kaye, J. , Leverenz, J. B. , Tsuang, D. , Longfellow, K. , Yearout, D. , Kukull, W. & 4 others Keene, C. D., Montine, T. J., Zabetian, C. P. & Trojanowski, J. Q. Jan 1 2017 In : The Lancet Neurology. 16, 1, p. 1234 1 p.

Research output: Contribution to journalArticle

Dementia
Alzheimer Disease
alpha-Synuclein
Survival
Neurofibrillary Tangles
3 Citations

Outcomes after diagnosis of mild cognitive impairment in a large autopsy series

Abner, E. L., Kryscio, R. J., Schmitt, F. A., Fardo, D. W., Moga, D. C., Ighodaro, E. T., Jicha, G. A., Yu, L., Dodge, H. H., Xiong, C., Woltjer, R. L., Schneider, J. A., Cairns, N. J., Bennett, D. A. & Nelson, P. T. 2017 (Accepted/In press) In : Annals of Neurology.

Research output: Contribution to journalArticle

Autopsy
Pathology
Dementia
Alzheimer Disease
Arteriolosclerosis
26 Citations

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Sims, R. , Van Der Lee, S. J. , Naj, A. C. , Bellenguez, C. , Badarinarayan, N. , Jakobsdottir, J. , Kunkle, B. W. , Boland, A. , Raybould, R. , Bis, J. C. , Martin, E. R. , Grenier-Boley, B. , Heilmann-Heimbach, S. , Chouraki, V. , Kuzma, A. B. , Sleegers, K. , Vronskaya, M. , Ruiz, A. , Graham, R. R. , Olaso, R. & 429 others Hoffmann, P., Grove, M. L., Vardarajan, B. N., Hiltunen, M., Nöthen, M. M., White, C. C., Hamilton-Nelson, K. L., Epelbaum, J., Maier, W., Choi, S. H., Beecham, G. W., Dulary, C., Herms, S., Smith, A. V., Funk, C. C., Derbois, C., Forstner, A. J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C. L., Valladares, O., Squassina, A., Thomas, R., Brody, J. A., Qu, L., Sánchez-Juan, P., Morgan, T., Wolters, F. J., Zhao, Y., Garcia, F. S., Denning, N., Fornage, M., Malamon, J., Naranjo, M. C. D., Majounie, E., Mosley, T. H., Dombroski, B., Wallon, D., Lupton, M. K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L. B., Panza, F., McGuinness, B., Moreno-Grau, S., Burgess, J. D., Solfrizzi, V., Proitsi, P., Adams, H. H., Allen, M., Seripa, D., Pastor, P., Cupples, L. A., Price, N. D., Hannequin, D., Frank-García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A. S., Giedraitis, V., Hampel, H., Garcia, M. E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P. K., Pasquier, F., Boccardi, V., Henández, I., Barber, R. C., Scherer, M., Tarraga, L., Adams, P. M., Leber, M., Chen, Y., Albert, M. S., Riedel-Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R. S., Spalletta, G., Jr, W. T. L., Fairchild, T. J., Bossù, P., Lopez, O. L., Frosch, M. P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R. M., Jessen, F., Li, S., Kamboh, M. I., Morris, J., Sotolongo-Grau, O., Katz, M. J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M. D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J. T., Lord, J., Turton, J., Hartmann, A. M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M. D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I. S., Brookes, K., Cupidi, C., Maletta, R. G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N. C., Hardy, J., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barnes, L. L., Barral, S., Beach, T. G., Becker, J. T., Bigio, E. H., Bird, T. D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Diaz, C. C., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Decarli, C., Dick, M., Duara, R., Evans, D. A., Faber, K. M., Fallon, K. B., Fardo, D. W., Farlow, M. R., Ferris, S., Foroud, T. M., Galasko, D. R., Gearing, M., Geschwind, D. H., Gilbert, J. R., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Abner, E., Jin, L. W., Jun, G., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Laferla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lunetta, K. L., Lyketsos, C. G., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Perry, W., Peskind, E., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Swerdlow, R. H., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Wilhelmsen, K. C., Williamson, J., Wingo, T. S., Woltjer, R. L., Wright, C. B., Yu, C. E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P. P., Fernadez, C. M., Benito, Y. A., Thonberg, H., Forsell, C., Lilius, L., Kinhult-Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A. M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J. J., Keene, C. D., Tschanz, J., Fitzpatrick, A. L., Kukull, W. A., Norton, M., Aspelund, T., Larson, E. B., Munger, R., Rotter, J. I., Lipton, R. B., Bullido, M. J., Hofman, A., Montine, T. J., Coto, E., Boerwinkle, E., Petersen, R. C., Alvarez, V., Rivadeneira, F., Reiman, E. M., Gallo, M., O'Donnell, C. J., Reisch, J. S., Bruni, A. C., Royall, D. R., Dichgans, M., Sano, M., Galimberti, D., St George-Hyslop, P., Scarpini, E., Tsuang, D. W., Mancuso, M., Bonuccelli, U., Winslow, A. R., Daniele, A., Wu, C. K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D. C., Bras, J., Guerreiro, R., Al-Chalabi, A., Shaw, C. E., Collinge, J., Mann, D., Tsolaki, M., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M. C., Owen, M. J., Behrens, T. W., Mead, S., Goate, A. M., Uitterlinden, A. G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D. A., Powell, J., Golde, T. E., Graff, C., De Jager, P. L., Morgan, K., Ertekin-Taner, N., Combarros, O., Psaty, B. M., Passmore, P., Younkin, S. G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D. W., Dartigues, J. F., Destefano, A. L., Ortega-Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J. K., Farrer, L. A., Van Broeckhoven, C., Ikram, M. A., Jones, L., Haines, J. L., Tzourio, C., Launer, L. J., Escott-Price, V., Mayeux, R., Deleuze, J. F., Amin, N., Holmans, P. A., Pericak-Vance, M. A., Amouyel, P., Van Duijn, C. M., Ramirez, A., Wang, L. S., Lambert, J. C., Seshadri, S., Williams, J. & Schellenberg, G. D. Sep 1 2017 In : Nature Genetics. 49, 9, p. 1373-1384 12 p.

Research output: Contribution to journalArticle

Innate Immunity
Gene Frequency
Alzheimer Disease
Odds Ratio
Microglia

Sex differences in the association of alcohol with cognitive decline and brain pathology in a cohort of octogenarians

Wardzala, C., Murchison, C., Loftis, J. M., Schenning, K. J., Mattek, N., Woltjer, R., Kaye, J., Quinn, J. F. & Wilhelm, C. J. Nov 29 2017 (Accepted/In press) In : Psychopharmacology. p. 1-10 10 p.

Research output: Contribution to journalArticle

Sex Characteristics
Alcohols
Pathology
Brain
Drinking
3 Citations

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

Jun, G. R. , Jun, G. R. , Chung, J. , Logue, M. W. , Sherva, R. , Farrer, L. A. , Mez, J. , Farrer, L. A. , Barber, R. , Beecham, G. W. , Hamilton-Nelson, K. L. , Kunkle, B. W. , Martin, E. R. , Pericak-Vance, M. A. , Bennett, D. A. , Logue, M. W. , Buxbaum, J. D. , Goate, A. M. , Buxbaum, J. D. , Buxbaum, J. D. & 31 others Byrd, G. S., Carrasquillo, M. M., Ertekin-Taner, N., Graff-Radford, N. R., Younkin, S. G., Crane, P. K., Mukherjee, S., Thornton, T., Cruchaga, C., Cruchaga, C., De Jager, P., De Jager, P., Larson, E. B., Evans, D., Fallin, M. D., Foroud, T. M., Friedland, R. P., Hendrie, H., Hendrie, H., Hall, K. S., Hall, K. S., Inzelberg, R., Kamboh, M. I., Kauwe, J. S. K., Kukull, W. A., Kukull, W. A., Kuwano, R., Kaye, J. A., Quinn, J. F., Woltjer, R. L. & Alzheimer's Disease Genetics Consortium Jul 1 2017 In : Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

Research output: Contribution to journalArticle

Alzheimer Disease
Genome
Single Nucleotide Polymorphism
Genome-Wide Association Study
Genetic Loci
2016
13 Citations

Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

Karch, C. M. , Ezerskiy, L. A. , Bertelsen, S. , Goate, A. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Baldwin, C. T. , Barber, R. , Barmada, M. M. , Barnes, L. L. , Beach, T. G. , Beecham, G. W. , Beekly, D. , Bennett, D. A. , Bigio, E. H. , Bird, T. D. , Blacker, D. , Boeve, B. F. & 144 others Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Crane, P. K., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton-Nelson, K. L., Hamilton, R. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Kamboh, M. I., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., Kukull, W. A., LaFerla, F. M., Lah, J. J., Larson, E. B., Leverenz, J. B., Levey, A. I., Li, G., Lin, C. F., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Myers, A. J., Naj, A. C., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Rajbhandary, R. A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L. Feb 1 2016 In : PLoS One. 11, 2, e0148717

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alzheimer disease
Polymorphism
Gene expression
Alzheimer Disease
38 Citations

A novel Alzheimer disease locus located near the gene encoding tau protein

Jun, G. , Ibrahim-Verbaas, C. A. , Vronskaya, M. , Lambert, J. C. , Chung, J. , Naj, A. C. , Kunkle, B. W. , Wang, L. S. , Bis, J. C. , Bellenguez, C. , Harold, D. , Lunetta, K. L. , Destefano, A. L. , Grenier-Boley, B. , Sims, R. , Beecham, G. W. , Smith, A. V. , Chouraki, V. , Hamilton-Nelson, K. L. , Ikram, M. A. & 32 others Fievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Kim, R., Raj, A., Wright, C. B., IGAP Consortium & Genetic and Environmental Risk in Alzheimer's Disease (GERAD) Consortium Jan 1 2016 In : Molecular Psychiatry. 21, 1, p. 108-117 10 p.

Research output: Contribution to journalArticle

tau Proteins
Single Nucleotide Polymorphism
Alzheimer Disease
Genes
Exons
4 Citations

Assessment of the genetic variance of late-onset Alzheimer's disease

Adams, P. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Asthana, S. , Atwood, C. S. , Baldwin, C. T. , Barber, R. C. , Barmada, M. M. , Barnes, L. L. , Barral, S. , Beach, T. G. , Becker, J. T. , Beecham, G. W. , Beekly, D. , Bennett, D. A. , Bigio, E. H. , Bird, T. D. , Blacker, D. & 31 others Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Burns, J. M., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., David, C. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Kaye, J. A., Quinn, J. F., Woltjer, R. L. & Alzheimer's Disease Genetics Consortium (ADGC) May 1 2016 In : Neurobiology of Aging. 41, p. 200.e13-200.e20

Research output: Contribution to journalArticle

Alzheimer Disease
Single Nucleotide Polymorphism
Inborn Genetic Diseases
Amyloid beta-Protein Precursor
Myeloid Cells
40 Citations

Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology

Abner, E. L., Nelson, P. T., Kryscio, R. J., Schmitt, F. A., Fardo, D. W., Woltjer, R. L., Cairns, N. J., Yu, L., Dodge, H. H., Xiong, C., Masaki, K., Tyas, S. L., Bennett, D. A., Schneider, J. A. & Arvanitakis, Z. 2016 (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Alzheimer Disease
Odds Ratio
Pathology
Neurofibrillary Tangles
Amyloid Plaques
3 Citations

Ferumoxytol-enhanced MRI differentiation of meningioma from dural metastases: a pilot study with immunohistochemical observations

Hamilton, B. E., Woltjer, R. L., Prola-Netto, J., Nesbit, G. M., Gahramanov, S., Pham, T., Wagner, J. & Neuwelt, E. A. Jul 8 2016 (Accepted/In press) In : Journal of Neuro-Oncology. p. 1-9 9 p.

Research output: Contribution to journalArticle

Ferrosoferric Oxide
Meningioma
Magnetic Resonance Imaging
Gadolinium
Neoplasm Metastasis
7 Citations

Ferumoxytol nanoparticle uptake in brain during acute neuroinflammation is cell-specific

McConnell, H. L., Schwartz, D. L., Richardson, B. E., Woltjer, R. L., Muldoon, L. L. & Neuwelt, E. A. Aug 1 2016 In : Nanomedicine: Nanotechnology, Biology, and Medicine. 12, 6, p. 1535-1542 8 p.

Research output: Contribution to journalArticle

Ferrosoferric Oxide
Nanoparticles
Magnetic resonance
Brain
Imaging techniques
1 Citations

IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma

Svalina, M. N. , Kikuchi, K. , Abraham, J. , Lal, S. , Davare, M. A. , Settelmeyer, T. P. , Young, M. C. , Peckham, J. L. , Cho, Y. J. , Michalek, J. E. , Hernandez, B. S. , Berlow, N. E. , Jackson, M. , Guillaume, D. J. , Selden, N. R. , Bigner, D. D. , Nazemi, K. J. , Green, S. C. , Corless, C. L. , Gultekin, S. & 4 others Mansoor, A., Rubin, B. P., Woltjer, R. & Keller, C. Jun 3 2016 In : Scientific Reports. 6, 27012

Research output: Contribution to journalArticle

Medulloblastoma
Peptide Hydrolases
Cerebrospinal Fluid
Neoplasm Metastasis
Plasminogen Activator Inhibitor 1
3 Citations

Immunopathology of Japanese macaque encephalomyelitis is similar to multiple sclerosis

Blair, T. C., Manoharan, M., Rawlings-Rhea, S. D., Tagge, I., Kohama, S. G., Hollister-Smith, J., Ferguson, B., Woltjer, R. L., Frederick, M. C., Pollaro, J., Rooney, W. D., Sherman, L. S., Bourdette, D. N. & Wong, S. W. Feb 15 2016 In : Journal of Neuroimmunology. 291, p. 1-10 10 p.

Research output: Contribution to journalArticle

Encephalomyelitis
Macaca
Multiple Sclerosis
Central Nervous System
T-Lymphocytes
4 Citations

Mixed neuropathologies and estimated rates of clinical progression in a large autopsy sample

Brenowitz, W. D., Hubbard, R. A., Keene, C. D., Hawes, S. E., Longstreth, W. T., Woltjer, R. L. & Kukull, W. A. 2016 (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Autopsy
Alzheimer Disease
Cerebrovascular Trauma
Lewy Body Disease
Neuropathology
34 Citations

Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia

Tuschl, K. , Meyer, E. , Valdivia, L. E. , Zhao, N. , Dadswell, C. , Abdul-Sada, A. , Hung, C. Y. , Simpson, M. A. , Chong, W. K. , Jacques, T. S. , Woltjer, R. L. , Eaton, S. , Gregory, A. , Sanford, L. , Kara, E. , Houlden, H. , Cuno, S. M. , Prokisch, H. , Valletta, L. , Tiranti, V. & 20 others Younis, R., Maher, E. R., Spencer, J., Straatman-Iwanowska, A., Gissen, P., Selim, L. A. M., Pintos-Morell, G., Coroleu-Lletget, W., Mohammad, S. S., Yoganathan, S., Dale, R. C., Thomas, M., Rihel, J., Bodamer, O. A., Enns, C. A., Hayflick, S. J., Clayton, P. T., Mills, P. B., Kurian, M. A. & Wilson, S. W. May 27 2016 In : Nature Communications. 7, 11601

Research output: Contribution to journalArticle

Dystonic Disorders
homeostasis
Parkinsonian Disorders
Manganese
mutations
3 Citations

Preserved neurogenesis in non-demented individuals with AD neuropathology

Briley, D., Ghirardi, V., Woltjer, R., Renck, A., Zolochevska, O., Taglialatela, G. & Micci, M. A. Jun 14 2016 In : Scientific Reports. 6, 27812

Research output: Contribution to journalArticle

Neurogenesis
Alzheimer Disease
Neural Stem Cells
MicroRNAs
Neuropathology
4 Citations

Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease

Dodge, H. H., Zhu, J., Woltjer, R., Nelson, P. T., Bennett, D. A., Cairns, N. J., Fardo, D. W., Kaye, J. A., Lyons, D. E., Mattek, N., Schneider, J. A., Silbert, L. C., Xiong, C., Yu, L., Schmitt, F. A., Kryscio, R. J. & Abner, E. L. 2016 (Accepted/In press) In : Alzheimer's and Dementia.

Research output: Contribution to journalArticle

Vascular Diseases
Alzheimer Disease
Pathology
Blood Vessels
Clinical Pathology
7 Citations

Spatio-temporal patterns of demyelination and remyelination in the cuprizone mouse model

Tagge, I., O'Connor, A., Chaudhary, P., Pollaro, J., Berlow, Y., Chalupsky, M., Bourdette, D., Woltjer, R., Johnson, M. & Rooney, W. Apr 1 2016 In : PLoS One. 11, 4, e0152480

Research output: Contribution to journalArticle

Cuprizone
Demyelinating Diseases
animal models
brain
Corpus Callosum
2015
3 Citations

A patient-derived xenograft model of parameningeal embryonal rhabdomyosarcoma for preclinical studies

Hooper, J. E., Cantor, E. L., Ehlen, M. S., Banerjee, A., Malempati, S., Stenzel, P., Woltjer, R. L., Gandour-Edwards, R., Goodwin, N. C., Yang, Y., Kaur, P., Bult, C. J., Airhart, S. D. & Keller, C. 2015 In : Sarcoma. 2015, 826124

Research output: Contribution to journalArticle

Embryonal Rhabdomyosarcoma
Heterografts
Neoplasms
Autopsy
Phosphotransferases
9 Citations

Association of long runs of homozygosity with Alzheimer disease among African American individuals

Ghani, M. , Reitz, C. , Cheng, R. , Vardarajan, B. N. , Jun, G. , Sato, C. , Naj, A. , Rajbhandary, R. , Wang, L. S. , Valladares, O. , Lin, C. F. , Larson, E. B. , Graff-Radford, N. R. , Evans, D. , De Jager, P. L. , Crane, P. K. , Buxbaum, J. D. , Murrell, J. R. , Raj, T. , Ertekin-Taner, N. & 30 others Logue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Kaye, J. A., Quinn, J. F. & Woltjer, R. L. Nov 1 2015 In : JAMA Neurology. 72, 11, p. 1313-1323 11 p.

Research output: Contribution to journalArticle

African Americans
Alzheimer Disease
Single Nucleotide Polymorphism
Consensus
Dementia
30 Citations

Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

Østergaard, S. D. , Mukherjee, S. , Sharp, S. J. , Proitsi, P. , Lotta, L. A. , Day, F. , Perry, J. R. B. , Boehme, K. L. , Walter, S. , Kauwe, J. S. , Gibbons, L. E. , Larson, E. B. , Powell, J. F. , Langenberg, C. , Crane, P. K. , Wareham, N. J. , Scott, R. A. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. & 33 others Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barber, R. C., Barmada, M. M., Barnes, L. L., Beach, T. G., Becker, J. T., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Kramer, J. H., Reiman, E. M., Yu, C. E., Alzheimer’s Disease Genetics Consortium, The GERAD1 Consortium & EPIC-InterAct Consortium Jun 1 2015 In : PLoS Medicine. 12, 6, e1001841

Research output: Contribution to journalArticle

Random Allocation
Single Nucleotide Polymorphism
Alzheimer Disease
Blood pressure
Smoking
9 Citations

Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses

Mukherjee, S. , Walter, S. , Kauwe, J. S. K. , Saykin, A. J. , Bennett, D. A. , Larson, E. B. , Crane, P. K. , Glymour, M. M. , Albert, M. S. , Albin, R. L. , Apostolova, L. G. , Arnold, S. E. , Asthana, S. , Atwood, C. S. , Baldwin, C. T. , Barber, R. C. , Barmada, M. M. , Barnes, L. L. , Beach, T. G. , Becker, J. T. & 158 others Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., Cruchaga, C., De Jager, P. L., DeCarli, C., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Evans, D., Faber, K. M., Fallon, K. B., Farlow, M. R., Farrer, L. A., Ferris, S., Foroud, T. M., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Goate, A. M., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Haines, J. L., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Hardy, J., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Kowall, N. W., Kramer, J. H., Kukull, W. A., Kunkle, B. W., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., Mayeux, R., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Myers, A. J., Naj, A. C., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Pericak-Vance, M. A., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Sager, M. A., Sano, M., Schellenberg, G. D., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., George-Hyslop, P. S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Wang, L. S., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L. Dec 1 2015 In : Alzheimer's and Dementia. 11, 12, p. 1439-1451 13 p.

Research output: Contribution to journalArticle

Mendelian Randomization Analysis
Alzheimer Disease
Body Mass Index
Phenotype
Odds Ratio
20 Citations
Frontal Lobe
Cerebrospinal Fluid
Dementia
Alzheimer Disease
Monoglycerides
1 Citations

Pallidal neuronal apolipoprotein E in pantothenate kinase-associated neurodegeneration recapitulates ischemic injury to the globus pallidus

Woltjer, R. L., Reese, L. C., Richardson, B. E., Tran, H., Green, S., Pham, T., Chalupsky, M., Gabriel, I., Light, T., Sanford, L., Jeong, S. Y., Hamada, J., Schwanemann, L. K., Rogers, C., Gregory, A., Hogarth, P. & Hayflick, S. J. 2015 In : Molecular Genetics and Metabolism. 116, 4, p. 289-297 9 p.

Research output: Contribution to journalArticle

Pantothenate Kinase-Associated Neurodegeneration
Globus Pallidus
Apolipoproteins E
Ubiquitin
Neurons
51 Citations

Progressive Aggregation of Alpha-Synuclein and Selective Degeneration of Lewy Inclusion-Bearing Neurons in a Mouse Model of Parkinsonism

Osterberg, V., Spinelli, K., Weston, L., Luk, K., Woltjer, R. & Unni, V. Mar 3 2015 In : Cell Reports. 10, 8, p. 1252-1260 9 p.

Research output: Contribution to journalArticle

Bearings (structural)
alpha-Synuclein
Parkinsonian Disorders
Neurons
Agglomeration
14 Citations

Rarity of the alzheimer disease-protective APP A673T variant in the United States

Wang, L. S. , Naj, A. C. , Graham, R. R. , Crane, P. K. , Kunkle, B. W. , Cruchaga, C. , Gonzalez Murcia, J. D. , Cannon-Albright, L. , Baldwin, C. T. , Zetterberg, H. , Blennow, K. , Kukull, W. A. , Faber, K. M. , Schupf, N. , Norton, M. C. , Tschanz, J. T. , Munger, R. G. , Corcoran, C. D. , Rogaeva, E. , Albert, M. S. & 157 others Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Barnes, L. L., Beach, T. G., Becker, J. T., Beecham, G. W., Beekly, D., Bennett, D. A., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Buxbaum, J. D., Cairns, N. J., Cao, C., Carlson, C. S., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Dickson, D. W., Duara, R., Ertekin-Taner, N., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Growdon, J. H., Hamilton, R. L., Hamilton-Nelson, K. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Jun, G., Kamboh, M. I., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lopez, O. L., Lunetta, K. L., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martin, E. R., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M. M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Murrell, J. R., Olichney, J. M., Parisi, J. E., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Reitz, C., Ringman, J. M., Roberson, E. D., Rosen, H. J., Rosenberg, R. N., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E., Yu, L., Lin, C. F., Dombroski, B. A., Cantwell, L. B., Partch, A., Valladares, O., Hakonarson, H., St George-Hyslop, P., Green, R. C., Goate, A. M., Foroud, T. M., Carney, R. M., Larson, E. B., Behrens, T. W., Kauwe, J. S. K., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Mayeux, R. & Schellenberg, G. D. Feb 1 2015 In : JAMA Neurology. 72, 2, p. 209-216 8 p.

Research output: Contribution to journalArticle

Amyloid beta-Protein Precursor
Alzheimer Disease
Genes
Sweden
Alanine
3 Citations

Synergistic antivascular and antitumor efficacy with combined cediranib and SC6889 in intracranial mouse glioma

Lobo, M. R., Kukino, A., Tran, H., Schabel, M. C., Springer, C. S., Gillespie, G. Y., Grafe, M. R., Woltjer, R. L. & Pike, M. M. Dec 1 2015 In : PLoS One. 10, 12, 0144488

Research output: Contribution to journalArticle

Glioma
Tumors
neoplasms
mice
proteasome endopeptidase complex
11 Citations
Diglycerides
Frontal Lobe
Alzheimer Disease
Monoglycerides
Unsaturated Fatty Acids
2014
25 Citations

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

Nelson, P. T. , Estus, S. , Abner, E. L. , Parikh, I. , Malik, M. , Neltner, J. H. , Ighodaro, E. , Wang, W. X. , Wilfred, B. R. , Wang, L. S. , Kukull, W. A. , Nandakumar, K. , Farman, M. L. , Poon, W. W. , Corrada, M. M. , Kawas, C. H. , Cribbs, D. H. , Bennett, D. A. , Schneider, J. A. , Larson, E. B. & 26 others Crane, P. K., Valladares, O., Schmitt, F. A., Kryscio, R. J., Jicha, G. A., Smith, C. D., Scheff, S. W., Sonnen, J. A., Haines, J. L., Pericak-Vance, M. A., Mayeux, R., Farrer, L. A., Van Eldik, L. J., Horbinski, C., Green, R. C., Gearing, M., Poon, L. W., Kramer, P. L., Woltjer, R. L., Montine, T. J., Partch, A. B., Rajic, A. J., Richmire, K., Monsell, S. E., Schellenberg, G. D. & Fardo, D. W. 2014 In : Acta Neuropathologica. 127, 6, p. 825-843 19 p.

Research output: Contribution to journalArticle

Sclerosis
Adenosine Triphosphate
Pathology
Single Nucleotide Polymorphism
Genome-Wide Association Study
26 Citations

Aggressive course in encephalitis with opsoclonus, ataxia, chorea, and seizures the first pediatric case of y-aminobutyric acid type B receptor autoimmunity

Kruer, M. C., Hoeftberger, R., Lim, K. Y., Coryell, J. C., Svoboda, M. D., Woltjer, R. L. & Dalmau, J. 2014 In : JAMA Neurology. 71, 5, p. 620-623 4 p.

Research output: Contribution to journalArticle

Aminobutyrates
Ocular Motility Disorders
Chorea
Encephalitis
Ataxia
7 Citations

Clinical significance of imaging and histological characteristics of filum terminale in tethered cord syndrome: Clinical article

Thompson, E. M., Strong, M. J., Warren, G., Woltjer, R. L. & Selden, N. R. 2014 In : Journal of Neurosurgery: Pediatrics. 13, 3, p. 255-259 5 p.

Research output: Contribution to journalArticle

Cauda Equina
Neural Tube Defects
Adipose Tissue
Urodynamics
Blood Vessels
4 Citations

Combined efficacy of cediranib and quinacrine in glioma is enhanced by hypoxia and causally linked to autophagic vacuole accumulation

Lobo, M. R., Wang, X., Gillespie, G. Y., Woltjer, R. L. & Pike, M. M. Dec 9 2014 In : PLoS One. 9, 12, e114110

Research output: Contribution to journalArticle

quinacrine
Quinacrine
Vacuoles
Glioma
vacuoles
10 Citations

Diagnosis of pseudoprogression using MRI perfusion in patients with glioblastoma multiforme may predict improved survival

Gahramanov, S., Varallyay, C., Tyson, R. M. A., Lacy, C., Fu, R., Netto, J. P. R., Nasseri, M., White, T., Woltjer, R. L., Gultekin, S. H. U. & Neuwelt, E. A. Nov 1 2014 In : CNS oncology. 3, 6, p. 389-400 12 p.

Research output: Contribution to journalArticle

Glioblastoma
Perfusion
Survival
Methylation
Ferrosoferric Oxide
58 Citations

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

Naj, A. C. , Jun, G. , Reitz, C. , Kunkle, B. W. , Perry, W. , Park, Y. S. , Beecham, G. W. , Rajbhandary, R. A. , Hamilton-Nelson, K. L. , Wang, L. S. , Kauwe, J. S. K. , Huentelman, M. J. , Myers, A. J. , Bird, T. D. , Boeve, B. F. , Baldwin, C. T. , Jarvik, G. P. , Crane, P. K. , Rogaeva, E. , Barmada, M. M. & 154 others Demirci, F. Y., Cruchaga, C., Kramer, P. L., Ertekin-Taner, N., Hardy, J., Graff-Radford, N. R., Green, R. C., Larson, E. B., St. George-Hyslop, P. H., Buxbaum, J. D., Evans, D. A., Schneider, J. A., Lunetta, K. L., Kamboh, M. I., Saykin, A. J., Reiman, E. M., De Jager, P. L., Bennett, D. A., Morris, J. C., Montine, T. J., Goate, A. M., Blacker, D., Tsuang, D. W., Hakonarson, H., Kukull, W. A., Foroud, T. M., Martin, E. R., Haines, J. L., Mayeux, R. P., Farrer, L. A., Schellenberg, G. D., Pericak-Vance, M. A., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barnes, L. L., Beach, T. G., Becker, J. T., Beekly, D., Bigio, E. H., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cantwell, L. B., Cao, C., Carlson, C. S., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Dick, M., Dickson, D. W., Duara, R., Faber, K. M., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Growdon, J. H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lopez, O. L., Lyketsos, C. G., Mack, W. J., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Marsel, M., Miller, B. L., Miller, C. A., Miller, J. W., Murrell, J. R., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Paulson, H. L., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Ringman, J. M., Roberson, E. D., Rosen, H. J., Rosenberg, R. N., Sano, M., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Valladares, O., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L. Nov 1 2014 In : JAMA Neurology. 71, 11, p. 1394-1404 11 p.

Research output: Contribution to journalArticle

Genetic Loci
Genome-Wide Association Study
Age of Onset
Alzheimer Disease
Genetic Databases
264 Citations

Primary age-related tauopathy (PART): a common pathology associated with human aging

Crary, J. F. , Trojanowski, J. Q. , Schneider, J. A. , Abisambra, J. F. , Abner, E. L. , Alafuzoff, I. , Arnold, S. E. , Attems, J. , Beach, T. G. , Bigio, E. H. , Cairns, N. J. , Dickson, D. W. , Gearing, M. , Grinberg, L. T. , Hof, P. R. , Hyman, B. T. , Jellinger, K. , Jicha, G. A. , Kovacs, G. G. , Knopman, D. S. & 23 others Kofler, J., Kukull, W. A., Mackenzie, I. R., Masliah, E., McKee, A., Montine, T. J., Murray, M. E., Neltner, J. H., Santa-Maria, I., Seeley, W. W., Serrano-Pozo, A., Shelanski, M. L., Stein, T., Takao, M., Thal, D. R., Toledo, J. B., Troncoso, J. C., Vonsattel, J. P., White, C. L., Wisniewski, T., Woltjer, R. L., Yamada, M. & Nelson, P. T. 2014 In : Acta Neuropathologica. 128, 6, p. 755-766 12 p.

Research output: Contribution to journalArticle

Tauopathies
Pathology
Neurofibrillary Tangles
Alzheimer Disease
Temporal Lobe
12 Citations

Role of soluble epoxide hydrolase in age-related vascular cognitive decline

Nelson, J. W., Young, J. M., Borkar, R. N., Woltjer, R. L., Quinn, J. F., Silbert, L. C., Grafe, M. R. & Alkayed, N. J. Sep 30 2014 In : Prostaglandins and Other Lipid Mediators. 113-115, p. 30-37 8 p.

Research output: Contribution to journalArticle

Epoxide Hydrolases
Blood Vessels
Eicosanoids
Brain
Tissue
50 Citations

TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions

Gallagher, M. D. , Suh, E. , Grossman, M. , Elman, L. , McCluskey, L. , Van Swieten, J. C. , Al-Sarraj, S. , Neumann, M. , Gelpi, E. , Ghetti, B. , Rohrer, J. D. , Halliday, G. , Van Broeckhoven, C. , Seilhean, D. , Shaw, P. J. , Frosch, M. P. , Alafuzoff, I. , Antonell, A. , Bogdanovic, N. , Brooks, W. & 56 others Cairns, N. J., Cooper-Knock, J., Cotman, C., Cras, P., Cruts, M., De Deyn, P. P., Decarli, C., Dobson-Stone, C., Engelborghs, S., Fox, N., Galasko, D., Gearing, M., Gijselinck, I., Grafman, J., Hartikainen, P., Hatanpaa, K. J., Highley, J. R., Hodges, J., Hulette, C., Ince, P. G., Jin, L. W., Kirby, J., Kofler, J., Kril, J., Kwok, J. B. J., Levey, A., Lieberman, A., Llado, A., Martin, J. J., Masliah, E., McDermott, C. J., McKee, A., McLean, C., Mead, S., Miller, C. A., Miller, J., Munoz, D. G., Murrell, J., Paulson, H., Piguet, O., Rossor, M., Sanchez-Valle, R., Sano, M., Schneider, J., Silbert, L. C., Spina, S., Van Der Zee, J., Van Langenhove, T., Warren, J., Wharton, S. B., White, C. L., Woltjer, R. L., Trojanowski, J. Q., Lee, V. M. Y., Van Deerlin, V. & Chen-Plotkin, A. S. Mar 2014 In : Acta Neuropathologica. 127, 3, p. 407-418 12 p.

Research output: Contribution to journalArticle

Frontotemporal Lobar Degeneration
Chromosomes, Human, Pair 9
Open Reading Frames
Age of Onset
Alleles
2013
1 Citations
Cognition Disorders
Antirheumatic Agents
X Ray Computed Tomography
Paresthesia
Neurologic Manifestations
50 Citations

Amyloid-β1-42 slows clearance of synaptically released glutamate by mislocalizing astrocytic GLT-1

Scimemi, A., Meabon, J. S., Woltjer, R. L., Sullivan, J. M., Diamond, J. S. & Cook, D. G. Mar 20 2013 In : Journal of Neuroscience. 33, 12, p. 5312-5318 7 p.

Research output: Contribution to journalArticle

Amino Acid Transport System X-AG
Amyloid
Glutamic Acid
Neuropil
Amyloid beta-Peptides
84 Citations

APOE ε4 increases risk for dementia in pure synucleinopathies

Tsuang, D. , Leverenz, J. B. , Lopez, O. L. , Hamilton, R. L. , Bennett, D. A. , Schneider, J. A. , Buchman, A. S. , Larson, E. B. , Crane, P. K. , Kaye, J. A. , Kramer, P. , Woltjer, R. , Trojanowski, J. Q. , Weintraub, D. , Chen-Plotkin, A. S. , Irwin, D. J. , Rick, J. , Schellenberg, G. D. , Watson, G. S. , Kukull, W. & 13 others Nelson, P. T., Jicha, G. A., Neltner, J. H., Galasko, D., Masliah, E., Quinn, J. F., Chung, K. A., Yearout, D., Mata, I. F., Wan, J. Y., Edwards, K. L., Montine, T. J. & Zabetian, C. P. 2013 In : JAMA Neurology. 70, 2, p. 223-228 6 p.

Research output: Contribution to journalArticle

Apolipoproteins E
Dementia
Lewy Body Disease
Alzheimer Disease
Parkinson Disease
59 Citations

Genes and pathways underlying regional and cell type changes in Alzheimer's disease

Miller, J. A., Woltjer, R. L., Goodenbour, J. M., Horvath, S. & Geschwind, D. H. May 25 2013 In : Genome Medicine. 5, 5, 48

Research output: Contribution to journalArticle

Alzheimer Disease
Genes
Gene Expression
Disease Progression
Gliosis