Peter Kurre

Professor

  • 1075 Citations
  • 20 h-Index
19992019
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Research Output 1999 2019

  • 1075 Citations
  • 20 h-Index
  • 60 Article
  • 3 Review article
  • 1 Comment/debate
  • 1 Editorial
2019

Extracellular vesicles impose quiescence on residual hematopoietic stem cells in the leukemic niche

Abdelhamed, S., Butler, J. T., Doron, B., Halse, A., Nemecek, E., Wilmarth, P., Marks, D., Chang, B., Horton, T. & Kurre, P., Jul 1 2019, In : EMBO Reports. 20, 7, e47546.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Stem cells
Acute Myeloid Leukemia
DNA
DNA Damage

Transmissible ER stress shapes the leukemic microenvironment

Butler, J. T. & Kurre, P., Jun 1 2019, In : Oncotarget. 10, 41, p. 4080-4082 3 p.

Research output: Contribution to journalEditorial

Unfolded Protein Response
Extracellular Vesicles
2018
14 Citations (Scopus)

Advances, challenges, and opportunities in extracellular RNA biology: insights from the NIH exRNA Strategic Workshop

Li, K., Rodosthenous, R. S., Kashanchi, F., Gingeras, T., Gould, S. J., Kuo, L. S., Kurre, P., Lee, H., Leonard, J. N., Liu, H., Lombo, T. B., Momma, S., Nolan, J. P., Ochocinska, M. J., Pegtel, D. M., Sadovsky, Y., Sánchez-Madrid, F., Valdes, K. M., Vickers, K. C., Weaver, A. M. & 5 others, Witwer, K. W., Zeng, Y., Das, S., Raffai, R. L. & Howcroft, T. K., Apr 5 2018, In : JCI insight. 3, 7

Research output: Contribution to journalReview article

Open Access
RNA
Education
Research
RNA Transport
Transducers
6 Citations (Scopus)

Concise Review: Adaptation of the Bone Marrow Stroma in Hematopoietic Malignancies: Current Concepts and Models

Doron, B., Handu, M. & Kurre, P., Jan 1 2018, (Accepted/In press) In : Stem Cells.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Hematopoietic Stem Cells
Bone Marrow
Leukemia
Stem Cell Niche
10 Citations (Scopus)

Extracellular vesicles in the hematopoietic microenvironment

Butler, J. T., Abdelhamed, S. & Kurre, P., Feb 28 2018, In : Haematologica. 103, 3, p. 382-394 13 p.

Research output: Contribution to journalReview article

Hematopoietic Stem Cells
Bone Marrow
Hematopoiesis
Cues
Extracellular Vesicles

Hematopoietic development: A gap in our understanding of inherited bone marrow failure

Kurre, P., Jan 1 2018, (Accepted/In press) In : Experimental Hematology.

Research output: Contribution to journalArticle

Bone Marrow
Hematopoietic Stem Cells
Hematopoiesis
Fetal Development
Parturition
2 Citations (Scopus)

Transmissible ER stress reconfigures the AML bone marrow compartment

Doron, B., Abdelhamed, S., Butler, J. T., Hashmi, S. K., Horton, T. M. & Kurre, P., Jan 1 2018, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Unfolded Protein Response
Bone Marrow
Stromal Cells
Heat-Shock Proteins
2017
1 Citation (Scopus)
Toll-Like Receptors
Luciferases
Mesenchymal Stromal Cells
Cytokines
Assays

Understanding the bone marrow microenvironment in hematologic malignancies: A focus on chemokine, integrin, and extracellular vesicle signaling

Sison, E. A. R., Kurre, P. & Kim, Y. M., Dec 5 2017, (Accepted/In press) In : Pediatric Hematology and Oncology. p. 1-14 14 p.

Research output: Contribution to journalArticle

Hematologic Neoplasms
Chemokines
Integrins
Leukemia
Bone Marrow
2016
22 Citations (Scopus)
Neoplasm Drug Resistance
Exosomes
Protein Kinase Inhibitors
MicroRNAs
Mesenchymal Stromal Cells
36 Citations (Scopus)

AML suppresses hematopoiesis by releasing exosomes that contain microRNAs targeting c-MYB

Hornick, N. I., Doron, B., Abdelhamed, S., Huan, J., Harrington, C. C., Shen, R., Cambronne, X., Verghese, S. C. & Kurre, P., Sep 6 2016, In : Science Signaling. 9, 444, ra88.

Research output: Contribution to journalArticle

Exosomes
Hematopoiesis
MicroRNAs
Acute Myeloid Leukemia
Hematopoietic Stem Cells
1 Citation (Scopus)

Anchored lentiviral vector episomes for stem cell gene therapy in fanconi anemia

Verghese, S. C. & Kurre, P., Oct 1 2016, In : Current Gene Therapy. 16, 5, p. 329-337 9 p.

Research output: Contribution to journalReview article

Fanconi Anemia
Cell- and Tissue-Based Therapy
Genetic Therapy
Plasmids
Stem Cells
3 Citations (Scopus)

Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2−/− Hematopoietic Stem and Progenitor Cells

Yoon, Y. M., Storm, K. J., Kamimae-Lanning, A. N., Goloviznina, N. A. & Kurre, P., Nov 8 2016, In : Stem Cell Reports. 7, 5, p. 840-853 14 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Hematopoietic Stem Cells
DNA Damage
DNA
Chemical activation
1 Citation (Scopus)

IFPA meeting 2016 workshop report I: Genomic communication, bioinformatics, trophoblast biology and transport systems

Albrecht, C., Baker, J. C., Blundell, C., Chavez, S., Carbone, L., Chamley, L., Hannibal, R. L., Illsley, N., Kurre, P., Laurent, L. C., McKenzie, C., Morales-Prieto, D., Pantham, P., Paquette, A., Powell, K., Price, N., Rao, B. M., Sadovsky, Y., Salomon, C., Tuteja, G. & 2 others, Wilson, S. & O'Tierney-Ginn, P. F., Dec 12 2016, (Accepted/In press) In : Placenta.

Research output: Contribution to journalArticle

Systems Biology
Trophoblasts
Computational Biology
Education
Pathology
11 Citations (Scopus)

Mesenchymal stromal cell-derived extracellular vesicles promote myeloid-biased multipotent hematopoietic progenitor expansion via toll-like receptor engagement

Goloviznina, N. A., Verghese, S. C., Yoon, Y. M., Taratula, O., Marks, D. & Kurre, P., Nov 18 2016, In : Journal of Biological Chemistry. 291, 47, p. 24607-24617 11 p.

Research output: Contribution to journalArticle

Toll-Like Receptors
Hematopoietic Stem Cells
Mesenchymal Stromal Cells
Crosstalk
Bone
1 Citation (Scopus)

Phenotypic correction of Fanconi anemia cells in the murine bone marrow after carrier cell mediated delivery of lentiviral vector

Chakkaramakkil Verghese, S., Goloviznina, N. A. & Kurre, P., Nov 19 2016, In : Stem Cell Research and Therapy. 7, 1, p. 1-7 7 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Bone
Stem cells
Bone Marrow
Hematopoietic Stem Cells
2015
36 Citations (Scopus)

Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes

Huan, J., Hornick, N. I., Goloviznina, N. A., Kamimae-Lanning, A. N., David, L., Wilmarth, P., Mori, M. T., Chevillet, J. R., Narla, A., Roberts, C., Loriaux, M., Chang, B. & Kurre, P., Jun 25 2015, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Exosomes
Hematopoietic Stem Cells
Acute Myeloid Leukemia
Bone Marrow
Exosome Multienzyme Ribonuclease Complex
1 Citation (Scopus)

Hope and hype surrounding circulating microRNA as potential next generation AML biomarkers

Abdelhamed, S. & Kurre, P., 2015, (Accepted/In press) In : Leukemia Research.

Research output: Contribution to journalArticle

Leukemic Gene Expression Regulation
Neoplasm RNA
Antineoplastic Combined Chemotherapy Protocols
MicroRNAs
Transcriptome
20 Citations (Scopus)

Maternal high-fat diet and obesity compromise fetal hematopoiesis

Kamimae-Lanning, A. N., Krasnow, S., Goloviznina, N. A., Zhu, X., Roth-Carter, Q. R., Levasseur, P. R., Jeng, S., McWeeney, S., Kurre, P. & Marks, D., Jan 1 2015, In : Molecular Metabolism. 4, 1, p. 25-38 14 p.

Research output: Contribution to journalArticle

Hematopoiesis
High Fat Diet
Hematopoietic Stem Cells
Obesity
Mothers
51 Citations (Scopus)

Self-Enforcing Feedback Activation between BCL6 and Pre-B Cell Receptor Signaling Defines a Distinct Subtype of Acute Lymphoblastic Leukemia

Geng, H., Hurtz, C., Lenz, K. B., Chen, Z., Baumjohann, D., Thompson, S., Goloviznina, N. A., Chen, W. Y., Huan, J., LaTocha, D., Ballabio, E., Xiao, G., Lee, J. W., Deucher, A., Qi, Z., Park, E., Huang, C., Nahar, R., Kweon, S. M., Shojaee, S. & 18 others, Chan, L. N., Yu, J., Kornblau, S. M., Bijl, J. J., Ye, B. H., Mark Ansel, K., Paietta, E., Melnick, A., Hunger, S. P., Kurre, P., Tyner, J., Loh, M. L., Roeder, R. G., Druker, B., Burger, J. A., Milne, T. A., Chang, B. & Müschen, M., Mar 9 2015, In : Cancer Cell. 27, 3, p. 409-425 17 p.

Research output: Contribution to journalArticle

Pre-B Cell Receptors
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Protein-Tyrosine Kinases
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
Clinical Trials
66 Citations (Scopus)

Serum Exosome MicroRNA as a minimally-invasive early biomarker of AML

Hornick, N. I., Huan, J., Doron, B., Goloviznina, N. A., Lapidus, J., Chang, B. & Kurre, P., Jun 12 2015, In : Scientific Reports. 5, 11295.

Research output: Contribution to journalArticle

Exosomes
MicroRNAs
Acute Myeloid Leukemia
Biomarkers
Serum
2014
14 Citations (Scopus)

Pearson marrow pancreas syndrome in patients suspected to have Diamond-Blackfan anemia

Gagne, K. E., Ghazvinian, R., Yuan, D., Zon, R. L., Storm, K., Mazur-Popinska, M., Andolina, L., Bubala, H., Golebiowska, S., Higman, M. A., Kalwak, K., Kurre, P., Matysiak, M., Niewiadomska, E., Pels, S., Petruzzi, M. J., Pobudejska-Pieniazek, A., Szczepanski, T., Fleming, M. D., Gazda, H. T. & 1 others, Agarwal, S., Jul 17 2014, In : Blood. 124, 3, p. 437-440 4 p.

Research output: Contribution to journalArticle

Diamond-Blackfan Anemia
Diamond
Mitochondrial DNA
Anemia
Pancreas
24 Citations (Scopus)

S/MAR sequence confers long-term mitotic stability on non-integrating lentiviral vector episomes without selection

Verghese, S. C., Goloviznina, N. A., Skinner, A., Lipps, H. J. & Kurre, P., 2014, In : Nucleic Acids Research. 42, 7

Research output: Contribution to journalArticle

Cell Division
Plasmids
Maintenance
Integrases
Chimerism
2013
8 Citations (Scopus)

Cell- Cell Transmission of VSV-G Pseudotyped Lentivector Particles

Skinner, A., Chakkaramakkil Verghese, S. & Kurre, P., Sep 10 2013, In : PLoS One. 8, 9, e74925.

Research output: Contribution to journalArticle

cells
Primate T-lymphotropic virus 1
Kinetics
Viruses
Human T-lymphotropic virus 1
18 Citations (Scopus)

Fetal origins of hematopoietic failure in a murine model of Fanconi anemia.

Kamimae-Lanning, A. N., Goloviznina, N. A. & Kurre, P., Mar 14 2013, In : Blood. 121, 11, p. 2008-2012 5 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Hematopoietic Stem Cells
Liver
Bone
Hematopoiesis
14 Citations (Scopus)

Immune markers of disease severity and treatment response in pediatric acquired aplastic anemia

Sutton, K. S., Shereck, E., Nemecek, E. & Kurre, P., Mar 2013, In : Pediatric Blood and Cancer. 60, 3, p. 455-460 6 p.

Research output: Contribution to journalArticle

Aplastic Anemia
Immune System Diseases
Biomarkers
Pediatrics
Natural Killer Cells
115 Citations (Scopus)

RNA trafficking by acute myelogenous leukemia exosomes

Huan, J., Hornick, N. I., Shurtleff, M. J., Skinner, A., Goloviznina, N. A., Roberts, C. & Kurre, P., Jan 15 2013, In : Cancer Research. 73, 2, p. 918-929 12 p.

Research output: Contribution to journalArticle

Exosomes
Acute Myeloid Leukemia
RNA
Bone Marrow
Cell Line
28 Citations (Scopus)

Vesicle trafficking and RNA transfer add complexity and connectivity to Cell-cell communication

Roberts, C. & Kurre, P., Jun 1 2013, In : Cancer Research. 73, 11, p. 3200-3205 6 p.

Research output: Contribution to journalArticle

Transfer RNA
Cell Communication
RNA
Small Untranslated RNA
Lipid Bilayers
2012
9 Citations (Scopus)

Intra-hematopoietic cell fusion as a source of somatic variation in the hematopoietic system

Skinner, A., Grompe, M. & Kurre, P., Jun 15 2012, In : Journal of Cell Science. 125, 12, p. 2837-2843 7 p.

Research output: Contribution to journalArticle

Hematopoietic System
Cell Fusion
Ploidies
Myeloid Cells
Genetic Markers
1 Citation (Scopus)

L-leucine alleviates Diamond-Blackfan anemia

Kamimae-Lanning, A. N. & Kurre, P., Sep 13 2012, In : Blood. 120, 11, p. 2157-2158 2 p.

Research output: Contribution to journalArticle

Diamond-Blackfan Anemia
Diamond
Essential Amino Acids
Erythropoiesis
Zebrafish
2 Citations (Scopus)

Programmed vesicle transfer of green fluorescent protein from a stably transduced cell line to primary hematopoietic cells

Russell, T. B., Skinner, A. & Kurre, P., Jun 5 2012, In : Blood. 119, 22, p. 5330-5332 3 p.

Research output: Contribution to journalArticle

Exosomes
Endosomes
Green Fluorescent Proteins
MicroRNAs
Cell Communication
2011
2 Citations (Scopus)

Costs and consequences of immunosuppressive therapy in children with aplastic anemia

Shereck, E., Deyell, R. J. & Kurre, P., Jun 2011, In : Haematologica. 96, 6, p. 793-795 3 p.

Research output: Contribution to journalArticle

Aplastic Anemia
Hematopoietic Stem Cell Transplantation
Homologous Transplantation
Immunosuppressive Agents
Immunosuppression
16 Citations (Scopus)

Treatment of Fanconi anemia patients using fludarabine and low-dose TBI, followed by unrelated donor hematopoietic cell transplantation

Thakar, M. S., Kurre, P., Storb, R., Kletzel, M., Frangoul, H., Pulsipher, M. A., Leisenring, W., Flowers, M. E. D., Sandmaier, B. M., Woolfrey, A. & Kiem, H. P., Apr 2011, In : Bone Marrow Transplantation. 46, 4, p. 539-544 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Unrelated Donors
Cell Transplantation
Therapeutics
Chimerism
2010
12 Citations (Scopus)

Double-negative T cells are non-ALPS-specific markers of immune dysregulation found in patients with aplastic anemia

Russell, T. B. & Kurre, P., Dec 2 2010, In : Blood. 116, 23, p. 5072-5073 2 p.

Research output: Contribution to journalArticle

Autoimmune Lymphoproliferative Syndrome
T-cells
Aplastic Anemia
T-Lymphocyte Subsets
Biomarkers
11 Citations (Scopus)

Entry kinetics and cell-cell transmission of surface-bound retroviral vector particles

O'Neill, L. S., Skinner, A., Woodward, J. A. & Kurre, P., May 2010, In : Journal of Gene Medicine. 12, 5, p. 463-476 14 p.

Research output: Contribution to journalArticle

Fibronectins
Extracellular Matrix
Lentivirus
Hematopoietic Stem Cells
Heparin

Paroxysmal nocturnal haemoglobinuria clones are part of the immune dysregulation in hepatitis-associated aplastic anaemia

Russell, T. B., Eroglu, Y., Zhang, Z. & Kurre, P., Jan 2010, In : Alimentary Pharmacology and Therapeutics. 31, 1, p. 164-165 2 p.

Research output: Contribution to journalArticle

Paroxysmal Hemoglobinuria
Aplastic Anemia
Immunosuppressive Agents
Hepatitis
Clone Cells
2009
1 Citation (Scopus)

Avoiding lentiviral transduction culture induced MSC senescence: Letter to the editor

Pan, Y. W. & Kurre, P., Jun 2009, In : Journal of Cellular and Molecular Medicine. 13, 6, p. 1186-1187 2 p.

Research output: Contribution to journalArticle

Genetic Transduction
Lentivirus
Cell Aging
Telomerase
Mesenchymal Stromal Cells
16 Citations (Scopus)

Cellular microvesicle pathways can be targeted to transfer genetic information between non-immune cells

Skinner, A., O'Neil, S. L. & Kurre, P., Jul 13 2009, In : PLoS One. 4, 7, e6219.

Research output: Contribution to journalArticle

Genes
Transfer RNA
Genome
cells
transfer RNA
16 Citations (Scopus)

CXCR4 but not CXCR7 is mainly implicated in ocular leukocyte trafficking during ovalbumin-induced acute uveitis

Zhang, Z., Zhong, W., Hall, M. J., Kurre, P., Spencer, D., Skinner, A., O'Neill, S., Xia, Z. & Rosenbaum, J. J., Oct 2009, In : Experimental Eye Research. 89, 4, p. 522-531 10 p.

Research output: Contribution to journalArticle

Uveitis
Ovalbumin
Leukocytes
T-Lymphocytes
Chemokine Receptors

Genetic correction of hematopoiesis in fanconi anemia: The case for a non-HSC-autonomous defect

Skinner, A. & Kurre, P., 2009, In : Molecular Therapy. 17, 8, p. 1313-1315 3 p.

Research output: Contribution to journalArticle

CD34 Antigens
Fanconi Anemia
Genetic Vectors
Lentivirus
Hematopoiesis

Is hematopoietic stem cell homing deficient in Fanconi anemia?

O'Neill, L., Skinner, A. & Kurre, P., 2009, In : Blood. 113, 21, p. 5361 1 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Hematopoietic Stem Cells
Cell Movement
2 Citations (Scopus)

MRI findings in aplastic anemia

De Mola, R. L. & Kurre, P., Nov 2009, In : American Journal of Hematology. 84, 11, p. 754 1 p.

Research output: Contribution to journalArticle

Bone Marrow Examination
Pancytopenia
Aplastic Anemia
Pelvis
Blood Cells
1 Citation (Scopus)
Diamond-Blackfan Anemia
Pancytopenia
Adenosine Deaminase
Aplastic Anemia
Young Adult
2008
10 Citations (Scopus)

CXCR4 induction in hematopoietic progenitor cells from Fanca-/-, -c-/-, and -d2-/- mice

Skinner, A., O'Neill, S. L., Grompe, M. & Kurre, P., Mar 2008, In : Experimental Hematology. 36, 3, p. 273-282 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Hematopoietic Stem Cells
Stem Cells
Chimerism
Genotype
8 Citations (Scopus)

Metachronous manifestations of Sweet's syndrome in a neutropenic patient with Fanconi anemia

Chatham-Stephens, K., Devere, T., Guzman-Cottrill, J. & Kurre, P., Jul 2008, In : Pediatric Blood and Cancer. 51, 1, p. 128-130 3 p.

Research output: Contribution to journalArticle

Sweet Syndrome
Fanconi Anemia
Dermis
Lung
Pancytopenia
2007
30 Citations (Scopus)

Multiarm high-throughput integration site detection: Limitations of LAM-PCR technology and optimization for clonal analysis

Harkey, M. A., Kaul, R., Jacobs, M. A., Kurre, P., Bovee, D., Levy, R. & Blau, C. A., Jun 2007, In : Stem Cells and Development. 16, 3, p. 381-392 12 p.

Research output: Contribution to journalArticle

Clone Cells
Technology
Polymerase Chain Reaction
Hematopoietic Stem Cells
Stem Cells
24 Citations (Scopus)

Prolonged adherence of human immunodeficiency virus-derived vector particles to hematopoietic target cells leads to secondary transduction in vitro and in vivo

Pan, Y. W., Scarlett, J. M., Luoh, T. T. & Kurre, P., Jan 2007, In : Journal of Virology. 81, 2, p. 639-649 11 p.

Research output: Contribution to journalArticle

Human immunodeficiency virus
Vesicular Stomatitis
HIV
Vesiculovirus
biosafety
2006
26 Citations (Scopus)

Rapid 1-hour transduction of whole bone marrow leads to long-term repopulation of murine recipients with lentivirus-modified hematopoietic stem cells

Kurre, P., Anandakumar, P. & Kiem, H. P., Feb 2006, In : Gene Therapy. 13, 4, p. 369-373 5 p.

Research output: Contribution to journalArticle

Lentivirus
Hematopoietic Stem Cells
Bone Marrow
Cytokines
HIV
2005
37 Citations (Scopus)

Diagnosis and treatment of children with aplastic anemia

Kurre, P., Johnson, F. L. & Deeg, H. J., Oct 2005, In : Pediatric Blood and Cancer. 45, 6, p. 770-780 11 p.

Research output: Contribution to journalArticle

Aplastic Anemia
Hematopoietic Stem Cell Transplantation
Immunosuppressive Agents
Tissue Donors
Therapeutics
2004
17 Citations (Scopus)

Efficient marking of murine long-term repopulating stem cells targeting unseparated marrow cells at low lentiviral vector particle concentration

Kurre, P., Anandakumar, P., Harkey, M. A., Thomasson, B. & Kiem, H. P., Jun 2004, In : Molecular Therapy. 9, 6, p. 914-922 9 p.

Research output: Contribution to journalArticle

Stem Cells
Bone Marrow
Infection
Lentivirus
Genes