Paul Spellman

Professor

  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
1992 …2021

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  • 2018

    Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

    The Cancer Genome Atlas Research Network, Apr 5 2018, In: Cell. 173, 2, p. 305-320.e10

    Research output: Contribution to journalArticlepeer-review

    106 Scopus citations
  • Report from the SWOG radiation oncology committee: Research objectives workshop 2017

    Okunieff, P., Casey-Sawicki, K., Lockney, N. A., Hoppe, B. S., Enderling, H., Pinnix, C., Welsh, J., Krishnan, S., Yothers, G., Brown, M., Knox, S., Bristow, R., Spellman, P., Mitin, T., Nabavizadeh, N., Jaboin, J., Manning, H. C., Feng, F., Galbraith, S., Solanki, A. A. & 17 others, Harkenrider, M. M., Tuli, R., Decker, R. H., Finkelstein, S. E., Hsu, C. C., Ha, C. S., Jagsi, R., Shumway, D., Daly, M., Wang, T. J. C., Fitzgerald, T. J., Laurie, F., Marshall, D. T., Raben, D., Constine, L., Thomas, C. R. & Kachnic, L. A., Aug 1 2018, In: Clinical Cancer Research. 24, 15, p. 3500-3509 10 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Scalable Open Science Approach for Mutation Calling of Tumor Exomes Using Multiple Genomic Pipelines

    MC3 Working Group & The Cancer Genome Atlas Research Network, Mar 28 2018, In: Cell Systems. 6, 3, p. 271-281.e7

    Research output: Contribution to journalArticlepeer-review

    168 Scopus citations
  • Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

    The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 282-296.e4

    Research output: Contribution to journalArticlepeer-review

    120 Scopus citations
  • Spatial Organization and Molecular Correlation of Tumor-Infiltrating Lymphocytes Using Deep Learning on Pathology Images

    The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 181-193.e7

    Research output: Contribution to journalArticlepeer-review

    209 Scopus citations
  • Systematic Analysis of Splice-Site-Creating Mutations in Cancer

    The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 270-281.e3

    Research output: Contribution to journalArticlepeer-review

    78 Scopus citations
  • The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

    The Cancer Genome Atlas Research Network, Apr 3 2018, In: Cell Reports. 23, 1, p. 313-326.e5

    Research output: Contribution to journalArticlepeer-review

    192 Scopus citations
  • The Immune Landscape of Cancer

    The Cancer Genome Atlas Research Network, Apr 17 2018, In: Immunity. 48, 4, p. 812-830.e14

    Research output: Contribution to journalArticlepeer-review

    940 Scopus citations
  • The Integrated Genomic Landscape of Thymic Epithelial Tumors

    The Cancer Genome Atlas Network, Feb 12 2018, In: Cancer Cell. 33, 2, p. 244-258.e10

    Research output: Contribution to journalArticlepeer-review

    77 Scopus citations
  • 2017

    Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

    The Cancer Genome Atlas Research Network, Nov 2 2017, In: Cell. 171, 4, p. 950-965.e28

    Research output: Contribution to journalArticlepeer-review

    265 Scopus citations
  • Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

    Hill, S. M., Nesser, N. K., Johnson-Camacho, K., Jeffress, M., Johnson, A., Boniface, C., Spencer, S. E. F., Lu, Y., Heiser, L. M., Lawrence, Y., Pande, N. T., Korkola, J. E., Gray, J. W., Mills, G. B., Mukherjee, S. & Spellman, P. T., Jan 25 2017, In: Cell Systems. 4, 1, p. 73-83.e10

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations
  • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

    Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B. & 251 others, Akbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., McWilliams, R., Chaffee, K., Oberg, A., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R. T., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J. J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In: Cancer Cell. 32, 2, p. 185-203.e13

    Research output: Contribution to journalArticlepeer-review

    526 Scopus citations
  • Physiologically activated mammary fibroblasts promote postpartum mammary cancer

    Guo, Q., Minnier, J., Burchard, J., Chiotti, K., Spellman, P. & Schedin, P., Mar 23 2017, In: JCI Insight. 2, 6, p. e89206

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • ΔN-ASPP2, a novel isoform of the ASPP2 tumor suppressor, promotes cellular survival

    Van Hook, K., Wang, Z., Chen, D., Nold, C., Zhu, Z., Anur, P., Lee, H. J., Yu, Z., Sheppard, B., Dai, M. S., Sears, R., Spellman, P. & Lopez, C. D., Jan 22 2017, In: Biochemical and Biophysical Research Communications. 482, 4, p. 1271-1277 7 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • 2016

    ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin

    Fleyshman, D., Cheney, P., Ströse, A., Mudambi, S., Safina, A., Commane, M., Purmal, A., Morgan, K., Wang, N. J., Gray, J., Spellman, P. T., Issaeva, N. & Gurova, K., Feb 1 2016, In: Cell Cycle. 15, 3, p. 455-470 16 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

    Linehan, W. M., Spellman, P. T., Ricketts, C. J., Creighton, C. J., Fei, S. S., Davis, C., Wheeler, D. A., Murray, B. A., Schmidt, L., Vocke, C. D., Peto, M., Al Mamun, A. A. M., Shinbrot, E., Sethi, A., Brooks, S., Rathmell, W. K., Brooks, A. N., Hoadley, K. A., Robertson, A. G., Brooks, D. & 208 others, Bowlby, R., Sadeghi, S., Shen, H., Weisenberger, D. J., Bootwalla, M., Baylin, S. B., Laird, P. W., Cherniack, A. D., Saksena, G., Haake, S., Li, J., Liang, H., Lu, Y., Mills, G. B., Akbani, R., Leiserson, M. D. M., Raphael, B. J., Anur, P., Bottaro, D., Albiges, L., Barnabas, N., Choueiri, T. K., Czerniak, B., Godwin, A. K., Hakimi, A. A., Ho, T. H., Hsieh, J., Ittmann, M., Kim, W. Y., Krishnan, B., Merino, M. J., Shaw, K. R. M., Reuter, V. E., Reznik, E., Shelley, C. S., Shuch, B., Signoretti, S., Srinivasan, R., Tamboli, P., Thomas, G., Tickoo, S., Burnett, K., Crain, D., Gardner, J., Lau, K., Mallery, D., Morris, S., Paulauskis, J. D., Penny, R. J., Shelton, C., Shelton, W. T., Sherman, M., Thompson, E., Yena, P., Avedon, M. T., Bowen, J., Gastier-Foster, J. M., Gerken, M., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Santos, T., Wise, L., Zmuda, E., Demchok, J. A., Felau, I., Hutter, C. M., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zenklusen, J. C., Zhang, J., Ayala, B., Baboud, J., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Ally, A., Balasundaram, M., Balu, S., Beroukhim, R., Bodenheimer, T., Buhay, C., Butterfield, Y. S. N., Carlsen, R., Carter, S. L., Chao, H., Chuah, E., Clarke, A., Covington, K. R., Dahdouli, M., Dewal, N., Dhalla, N., Doddapaneni, H. V., Drummond, J. A., Gabriel, S. B., Gibbs, R. A., Guin, R., Hale, W., Hawes, A., Hayes, D. N., Holt, R. A., Hoyle, A. P., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kalra, D., Kovar, C., Lewis, L., Li, J., Ma, Y., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Morton, D., Mose, L. E., Mungall, A. J., Muzny, D., Parker, J. S., Perou, C. M., Roach, J., Schein, J. E., Schumacher, S. E., Shi, Y., Simons, J. V., Sipahimalani, P., Skelly, T., Soloway, M. G., Sougnez, C., Tam, A., Tan, D., Thiessen, N., Veluvolu, U., Wang, M., Wilkerson, M. D., Wong, T., Wu, J., Xi, L., Zhou, J., Bedford, J., Chen, F., Fu, Y., Gerstein, M., Haussler, D., Kasaian, K., Lai, P., Ling, S., Radenbaugh, A., Van Den Berg, D., Weinstein, J. N., Zhu, J., Albert, M., Alexopoulou, I., Andersen, J. J., Auman, J. T., Bartlett, J., Bastacky, S., Bergsten, J., Blute, M. L., Boice, L., Bollag, R. J., Boyd, J., Castle, E., Chen, Y. B., Cheville, J. C., Curley, E., Davies, B., DeVolk, A., Dhir, R., Dike, L., Eckman, J., Engel, J., Harr, J., Hrebinko, R., Huang, M., Huelsenbeck-Dill, L., Iacocca, M., Jacobs, B., Lobis, M., Maranchie, J. K., McMeekin, S., Myers, J., Nelson, J., Parfitt, J., Parwani, A., Petrelli, N., Rabeno, B., Roy, S., Salner, A. L., Slaton, J., Stanton, M., Thompson, R. H., Thorne, L., Tucker, K., Weinberger, P. M., Winemiller, C., Zach, L. A. & Zuna, R., Jan 14 2016, In: New England Journal of Medicine. 374, 2, p. 135-145 11 p.

    Research output: Contribution to journalArticlepeer-review

    650 Scopus citations
  • FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

    Fu, X., Jeselsohn, R., Pereira, R., Hollingsworth, E. F., Creighton, C. J., Li, F., Shea, M., Nardone, A., De Angelis, C., Heiser, L. M., Anur, P., Wang, N., Grasso, C. S., Spellman, P. T., Griffith, O. L., Tsimelzon, A., Gutierrez, C., Huang, S., Edwards, D. P., Trivedi, M. V. & 7 others, Rimawi, M. F., Lopez-Terrada, D., Hilsenbeck, S. G., Gray, J. W., Brown, M., Osborne, C. K. & Schiff, R., Oct 25 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 43, p. E6600-E6609

    Research output: Contribution to journalArticlepeer-review

    78 Scopus citations
  • Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

    Hu, Z., Mao, J. H., Curtis, C., Huang, G., Gu, S., Heiser, L., Lenburg, M. E., Korkola, J. E., Bayani, N., Samarajiwa, S., Seoane, J. A., Dane, M., Esch, A., Feiler, H. S., Wang, N. J., Hardwicke, M. A., Laquerre, S., Jackson, J., Wood, K., Weber, B. & 5 others, Spellman, P. T., Aparicio, S., Wooster, R., Caldas, C. & Gray, J. W., Jul 1 2016, In: Breast Cancer Research. 18, 1, 70.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Identification of shared TCR sequences from T cells in human breast cancer Using emulsion RT-PCR

    Munson, D. J., Egelston, C. A., Chiotti, K. E., Parra, Z. E., Bruno, T. C., Moore, B. L., Nakano, T. A., Simons, D. L., Jimenez, G., Yim, J. H., Rozanov, D. V., Falta, M. T., Fontenot, A. P., Reynolds, P. R., Leach, S. M., Borges, V. F., Kappler, J. W., Spellman, P. T., Lee, P. P. & Slansky, J. E., Jul 19 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 29, p. 8272-8277 6 p.

    Research output: Contribution to journalArticlepeer-review

    34 Scopus citations
  • Inferring causal molecular networks: Empirical assessment through a community-based effort

    Hill, S. M., Heiser, L. M., Cokelaer, T., Linger, M., Nesser, N. K., Carlin, D. E., Zhang, Y., Sokolov, A., Paull, E. O., Wong, C. K., Graim, K., Bivol, A., Wang, H., Zhu, F., Afsari, B., Danilova, L. V., Favorov, A. V., Lee, W. S., Taylor, D., Hu, C. W. & 115 others, Long, B. L., Noren, D. P., Bisberg, A. J., Mills, G. B., Gray, J. W., Kellen, M., Norman, T., Friend, S., Qutub, A. A., Fertig, E. J., Guan, Y., Song, M., Stuart, J. M., Spellman, P. T., Koeppl, H., Stolovitzky, G., Saez-Rodriguez, J., Mukherjee, S., Al-Ouran, R., Anton, B., Arodz, T., Sichani, O. A., Bagheri, N., Berlow, N., Bohler, A., Bonet, J., Bonneau, R., Budak, G., Bunescu, R., Caglar, M., Cai, B., Cai, C., Carlon, A., Chen, L., Ciaccio, M. F., Cooper, G., Coort, S., Creighton, C. J., Daneshmand, S. M. H., De La Fuente, A., Di Camillo, B., Dutta-Moscato, J., Emmett, K., Evelo, C., Fassia, M. K. H., Finotello, F., Finkle, J. D., Gao, X., Garcia-Garcia, J., Ghosh, S., Giaretta, A., Großeholz, R., Guinney, J., Hafemeister, C., Hahn, O., Haider, S., Hase, T., Hodgson, J., Hoff, B., Hsu, C. H., Hu, Y., Huang, X., Jalili, M., Jiang, X., Kacprowski, T., Kaderali, L., Kang, M., Kannan, V., Kikuchi, K., Kim, D. C., Kitano, H., Knapp, B., Komatsoulis, G., Krämer, A., Kursa, M. B., Kutmon, M., Li, Y., Liang, X., Liu, Z., Liu, Y., Lu, S., Lu, X., Manfrini, M., Matos, M. R. A., Meerzaman, D., Min, W., Müller, C. L., Neapolitan, R. E., Oliva, B., Opiyo, S. O., Pal, R., Palinkas, A., Planas-Iglesias, J., Poglayen, D., Sambo, F., Sanavia, T., Sharifi-Zarchi, A., Slawek, J., Streck, A., Strunz, S., Tegnér, J., Thobe, K., Toffolo, G. M., Trifoglio, E., Unger, M., Wan, Q., Welch, L., Wu, J. J., Xue, A. Y., Yamanaka, R., Yan, C., Zairis, S., Zengerling, M., Zenil, H. & Zi, Z., Mar 30 2016, In: Nature Methods. 13, 4, p. 310-322 13 p.

    Research output: Contribution to journalArticlepeer-review

    126 Scopus citations
  • Patient-specific factors influence somatic variation patterns in von Hippel-Lindau disease renal tumours

    Fei, S. S., Mitchell, A. D., Heskett, M. B., Vocke, C. D., Ricketts, C. J., Peto, M., Wang, N. J., Sönmez, K., Linehan, W. M. & Spellman, P. T., May 13 2016, In: Nature communications. 7, 11588.

    Research output: Contribution to journalArticlepeer-review

    16 Scopus citations
  • 2015

    A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

    Alioto, T. S., Buchhalter, I., Derdak, S., Hutter, B., Eldridge, M. D., Hovig, E., Heisler, L. E., Beck, T. A., Simpson, J. T., Tonon, L., Sertier, A. S., Patch, A. M., Jäger, N., Ginsbach, P., Drews, R., Paramasivam, N., Kabbe, R., Chotewutmontri, S., Diessl, N., Previti, C. & 63 others, Schmidt, S., Brors, B., Feuerbach, L., Heinold, M., Gröbner, S., Korshunov, A., Tarpey, P. S., Butler, A. P., Hinton, J., Jones, D., Menzies, A., Raine, K., Shepherd, R., Stebbings, L., Teague, J. W., Ribeca, P., Giner, F. C., Beltran, S., Raineri, E., Dabad, M., Heath, S. C., Gut, M., Denroche, R. E., Harding, N. J., Yamaguchi, T. N., Fujimoto, A., Nakagawa, H., Quesada, V., Valdés-Mas, R., Nakken, S., Vodák, D., Bower, L., Lynch, A. G., Anderson, C. L., Waddell, N., Pearson, J. V., Grimmond, S. M., Peto, M., Spellman, P., He, M., Kandoth, C., Lee, S., Zhang, J., Létourneau, L., Ma, S., Seth, S., Torrents, D., Xi, L., Wheeler, D. A., López-Otín, C., Campo, E., Campbell, P. J., Boutros, P. C., Puente, X. S., Gerhard, D. S., Pfister, S. M., McPherson, J. D., Hudson, T. J., Schlesner, M., Lichter, P., Eils, R., Jones, D. T. W. & Gut, I. G., Dec 9 2015, In: Nature communications. 6, 10001.

    Research output: Contribution to journalArticlepeer-review

    162 Scopus citations
  • A humanized leucine zipper-TRAIL hybrid induces apoptosis of tumors both in vitro and in vivo

    Rozanov, D., Spellman, P., Savinov, A. & Strongin, A. Y., Apr 7 2015, In: PloS one. 10, 4, e0122980.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Association of somatic mutations of ADAMTS genes with chemotherapy sensitivity and survival in high-grade serous ovarian carcinoma

    Liu, Y., Yasukawa, M., Chen, K., Hu, L., Broaddus, R. R., Ding, L., Mardis, E. R., Spellman, P., Levine, D. A., Mills, G. B., Shmulevich, I., Sood, A. K. & Zhang, W., Jul 1 2015, In: JAMA Oncology. 1, 4, p. 486-494 9 p.

    Research output: Contribution to journalArticlepeer-review

    29 Scopus citations
  • Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

    Korkola, J. E., Collisson, E. A., Heiser, L., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N. J., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T., Tomlin, C. & 3 others, Mukherjee, S., Gray, J. W. & Jakkula, L., Jul 16 2015, In: PloS one. 10, 7, e0133219.

    Research output: Contribution to journalArticlepeer-review

    14 Scopus citations
  • Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease

    Butler, T. M., Johnson-Camacho, K., Peto, M., Wang, N. J., Macey, T. A., Korkola, J. E., Koppie, T. M., Corless, C. L., Gray, J. W. & Spellman, P. T., Aug 28 2015, In: PloS one. 10, 8, e0136407.

    Research output: Contribution to journalArticlepeer-review

    73 Scopus citations
  • Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

    Grasso, C. S., Tang, Y., Truffaux, N., Berlow, N. E., Liu, L., Debily, M. A., Quist, M. J., Davis, L. E., Huang, E. C., Woo, P. J., Ponnuswami, A., Chen, S., Johung, T. B., Sun, W., Kogiso, M., Du, Y., Qi, L., Huang, Y., Hütt-Cabezas, M., Warren, K. E. & 20 others, Le Dret, L., Meltzer, P. S., Mao, H., Quezado, M., Van Vuurden, D. G., Abraham, J., Fouladi, M., Svalina, M. N., Wang, N., Hawkins, C., Nazarian, J., Alonso, M. M., Raabe, E. H., Hulleman, E., Spellman, P. T., Li, X. N., Keller, C., Pal, R., Grill, J. & Monje, M., Jun 9 2015, In: Nature medicine. 21, 6, p. 555-559 5 p.

    Research output: Contribution to journalArticlepeer-review

    289 Scopus citations
  • Non-random fragmentation patterns in circulating cell-free DNA reflect epigenetic regulation

    Ivanov, M., Baranova, A., Butler, T., Spellman, P. & Mileyko, V., Dec 16 2015, In: BMC Genomics. 16, 13, S1.

    Research output: Contribution to journalArticlepeer-review

    54 Scopus citations
  • Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination

    Sanborn, J. Z., Chung, J., Purdom, E., Wang, N. J., Kakavand, H., Wilmott, J. S., Butler, T., Thompson, J. F., Mann, G. J., Haydu, L. E., Saw, R. P. M., Busam, K. J., Lo, R. S., Collisson, E. A., Hur, J. S., Spellman, P. T., Cleaver, J. E., Gray, J. W., Huh, N., Murali, R. & 3 others, Scolyer, R. A., Bastian, B. C. & Cho, R. J., Sep 1 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 35, p. 10995-11000 6 p.

    Research output: Contribution to journalArticlepeer-review

    92 Scopus citations
  • Src and STAT3 inhibitors synergize to promote tumor inhibition in renal cell carcinoma

    Lue, H. W., Cole, B., Rao, S. A. M., Podolak, J., Van Gaest, A., King, C., Eide, C. A., Wilmot, B., Xue, C., Spellman, P. T., Heiser, L. M., Tyner, J. W. & Thomas, G. V., 2015, In: Oncotarget. 6, 42, p. 44675-44687 13 p.

    Research output: Contribution to journalArticlepeer-review

    22 Scopus citations
  • Stacked Predictive Sparse Decomposition for Classification of Histology Sections

    Chang, H., Zhou, Y., Borowsky, A., Barner, K., Spellman, P. & Parvin, B., May 1 2015, In: International Journal of Computer Vision. 113, 1, p. 3-18 16 p.

    Research output: Contribution to journalArticlepeer-review

    26 Scopus citations
  • TRAIL-based high throughput screening reveals a link between TRAIL-mediated apoptosis and glutathione reductase, a key component of oxidative stress response

    Rozanov, D., Cheltsov, A., Sergienko, E., Vasile, S., Golubkov, V., Aleshin, A. E., Levin, T., Traer, E., Hann, B., Freimuth, J., Alexeev, N., Alekseyev, M. A., Budko, S. P., Bächinger, H. P. & Spellman, P., Jun 15 2015, In: PloS one. 10, 6, e0129566.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • 2014

    Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

    Collisson, E. A., Campbell, J. D., Brooks, A. N., Berger, A. H., Lee, W., Chmielecki, J., Beer, D. G., Cope, L., Creighton, C. J., Danilova, L., Ding, L., Getz, G., Hammerman, P. S., Hayes, D. N., Hernandez, B., Herman, J. G., Heymach, J. V., Jurisica, I., Kucherlapati, R., Kwiatkowski, D. & 290 others, Ladanyi, M., Robertson, G., Schultz, N., Shen, R., Sinha, R., Sougnez, C., Tsao, M. S., Travis, W. D., Weinstein, J. N., Wigle, D. A., Wilkerson, M. D., Chu, A., Cherniack, A. D., Hadjipanayis, A., Rosenberg, M., Weisenberger, D. J., Laird, P. W., Radenbaugh, A., Ma, S., Stuart, J. M., Byers, L. A., Baylin, S. B., Govindan, R., Meyerson, M., Gabriel, S. B., Cibulskis, K., Kim, J., Stewart, C., Lichtenstein, L., Lander, E. S., Lawrence, M. S., Getz, E., Fulton, R., Fulton, L. L., McLellan, M. D., Wilson, R. K., Ye, K., Fronick, C. C., Maher, C. A., Miller, C. A., Wendl, M. C., Cabanski, C., Mardis, E., Wheeler, D., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Chuah, E., Dhalla, N., Guin, R., Hirst, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R., Robertson, A. G., Wye, N., Thiessen, N., Holt, R. A., Jones, S. J. M., Marra, M. A., Imielinski, M., Onofrio, R. C., Hodis, E., Zack, T., Helman, E., Pedamallu, C. S., Mesirov, J., Saksena, G., Schumacher, S. E., Carter, S. L., Garraway, L., Beroukhim, R., Lee, S., Mahadeshwar, H. S., Pantazi, A., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Yang, L., Zhang, J., Chen, P. C., Parfenov, M., Xu, A. W., Santoso, N., Chin, L., Park, P. J., Hoadley, K. A., Auman, J. T., Meng, S., Shi, Y., Buda, E., Waring, S., Veluvolu, U., Tan, D., Mieczkowski, P. A., Jones, C. D., Simons, J. V., Soloway, M. G., Bodenheimer, T., Jefferys, S. R., Roach, J., Hoyle, A. P., Wu, J., Balu, S., Singh, D., Prins, J. F., Marron, J. S., Parker, J. S., Perou, C. M., Liu, J., Maglinte, D. T., Lai, P. H., Bootwalla, M. S., Van Den Berg, D. J., Triche, T., Cho, J., DiCara, D., Heiman, D., Lin, P., Mallard, W., Voet, D., Zhang, H., Zou, L., Noble, M. S., Gehlenborg, N., Thorvaldsdottir, H., Nazaire, M. D., Robinson, J., Aksoy, B. A., Ciriello, G., Taylor, B. S., Dresdner, G., Gao, J., Gross, B., Seshan, V. E., Reva, B., Sumer, S. O., Weinhold, N., Sander, C., Ng, S., Zhu, J., Benz, C. C., Yau, C., Haussler, D., Spellman, P. T., Kimes, P. K., Broom, B. M., Wang, J., Lu, Y., Ng, P. K. S., Diao, L., Liu, W., Amos, C. I., Akbani, R., Mills, G. B., Curley, E., Paulauskis, J., Lau, K., Morris, S., Shelton, T., Mallery, D., Gardner, J., Penny, R., Saller, C., Tarvin, K., Richards, W. G., Cerfolio, R., Bryant, A., Raymond, D. P., Pennell, N. A., Farver, C., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Brown, J., Bauer, T., Dolzhanskiy, C. O., Potapova, O., Rotin, D., Voronina, O., Nemirovich-Danchenko, E., Fedosenko, K. V., Gal, A., Behera, M., Ramalingam, S. S., Sica, G., Flieder, D., Boyd, J., Weaver, J. E., Kohl, B., Thinh, D. H. Q., Sandusky, G., Juhl, H., Duhig, E., Illei, P., Gabrielson, E., Shin, J., Lee, B., Rogers, K., Trusty, D., Brock, M. V., Williamson, C., Burks, E., Rieger-Christ, K., Holway, A., Sullivan, T., Asiedu, M. K., Kosari, F., Rekhtman, N., Zakowski, M., Rusch, V. W., Zippile, P., Suh, J., Pass, H., Goparaju, C., Owusu-Sarpong, Y., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Sekhon, H., Albert, M., Eckman, J., Myers, J. B., Morrison, C., Gaudioso, C., Borgia, J. A., Bonomi, P., Pool, M., Liptay, M. J., Moiseenko, F., Zaytseva, I., Dienemann, H., Meister, M., Schnabel, P. A., Muley, T. R., Peifer, M., Gomez-Fernandez, C., Herbert, L., Egea, S., Huang, M., Thorne, L. B., Boice, L., Salazar, A. H., Funkhouser, W. K., Rathmell, W. K., Dhir, R., Yousem, S. A., Dacic, S., Schneider, F., Siegfried, J. M., Hajek, R., Watson, M. A., McDonald, S., Meyers, B., Clarke, B., Yang, I. A., Fong, K. M., Hunter, L., Windsor, M., Bowman, R. V., Peters, S., Letovanec, I., Khan, K. Z., Jensen, M. A., Snyder, E. E., Srinivasan, D., Kahn, A. B., Baboud, J., Pot, D. A., Shaw, K. R. M., Sheth, M., Davidsen, T., Demchok, J. A., Yang, L., Wang, Z., Tarnuzzer, R., Zenklusen, J. C., Ozenberger, B. A., Sofia, H. J. & Cheney, R., 2014, In: Nature. 511, 7511, p. 543-550 8 p.

    Research output: Contribution to journalArticlepeer-review

    2830 Scopus citations
  • Integrated analysis of germline and somatic variants in ovarian cancer

    Kanchi, K. L., Johnson, K. J., Lu, C., McLellan, M. D., Leiserson, M. D. M., Wendl, M. C., Zhang, Q., Koboldt, D. C., Xie, M., Kandoth, C., McMichael, J. F., Wyczalkowski, M. A., Larson, D. E., Schmidt, H. K., Miller, C. A., Fulton, R. S., Spellman, P. T., Mardis, E. R., Druley, T. E., Graubert, T. A. & 4 others, Goodfellow, P. J., Raphael, B. J., Wilson, R. K. & Ding, L., Jan 22 2014, In: Nature communications. 5, 3156.

    Research output: Contribution to journalArticlepeer-review

    172 Scopus citations
  • Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

    The Cancer Genome Atlas Research Network, Aug 14 2014, In: Cell. 158, 4, p. 929-944 16 p.

    Research output: Contribution to journalArticlepeer-review

    843 Scopus citations
  • Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase

    Fu, X., Creighton, C. J., Biswal, N. C., Kumar, V., Shea, M., Herrera, S., Contreras, A., Gutierrez, C., Wang, T., Nanda, S., Giuliano, M., Morrison, G., Nardone, A., Karlin, K. L., Westbrook, T. F., Heiser, L. M., Anur, P., Spellman, P., Guichard, S. M., Smith, P. D. & 10 others, Davies, B. R., Klinowska, T., Lee, A. V., Mills, G. B., Rimawi, M. F., Hilsenbeck, S. G., Gray, J. W., Joshi, A., Osborne, C. K. & Schiff, R., Sep 11 2014, In: Breast Cancer Research. 16, 5, 430.

    Research output: Contribution to journalArticlepeer-review

    55 Scopus citations
  • The somatic genomic landscape of chromophobe renal cell carcinoma

    The Cancer Genome Atlas Research Network, 2014, In: Cancer Cell. 26, 3, p. 319-330 12 p.

    Research output: Contribution to journalArticlepeer-review

    446 Scopus citations
  • Transcription Restores DNA Repair to Heterochromatin, Determining Regional Mutation Rates in Cancer Genomes

    Zheng, C. L., Wang, N. J., Chung, J., Moslehi, H., Sanborn, J. Z., Hur, J. S., Collisson, E. A., Vemula, S. S., Naujokas, A., Chiotti, K. E., Cheng, J. B., Fassihi, H., Blumberg, A. J., Bailey, C. V., Fudem, G. M., Mihm, F. G., Cunningham, B. B., Neuhaus, I. M., Liao, W., Oh, D. H. & 10 others, Cleaver, J. E., LeBoit, P. E., Costello, J. F., Lehmann, A. R., Gray, J. W., Spellman, P. T., Arron, S. T., Huh, N., Purdom, E. & Cho, R. J., Nov 20 2014, In: Cell Reports. 9, 4, p. 1228-1234 7 p.

    Research output: Contribution to journalArticlepeer-review

    62 Scopus citations
  • 2013

    A robust prognostic signature for hormone-positive node-negative breast cancer

    Griffith, O. L., Pepin, F., Enache, O. M., Heiser, L. M., Collisson, E. A., Spellman, P. T. & Gray, J. W., Oct 11 2013, In: Genome Medicine. 5, 10, 92.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • Comprehensivemolecular characterization of clear cell renal cell carcinoma

    Creighton, C. J., Morgan, M., Gunaratne, P. H., Wheeler, D. A., Gibbs, R. A., Robertson, G., Chu, A., Beroukhim, R., Cibulskis, K., Signoretti, S., Vandin, F., Wu, H. T., Raphael, B. J., Verhaak, R. G. W., Tamboli, P., Torres-Garcia, W., Akbani, R., Weinstein, J. N., Reuter, V., Hsieh, J. J. & 268 others, Brannon, A. R., Hakimi, A. A., Jacobsen, A., Ciriello, G., Reva, B., Ricketts, C. J., Linehan, W. M., Stuart, J. M., Rathmell, W. K., Hui, S., Laird, P. W., Muzny, D., Davis, C., Liu, X., Chang, K., Kakkar, N., Treviño, L. R., Benton, S., Reid, J. G., Morton, D., Doddapaneni, H., Yi, H., Lewis, L., Huyen, D., Kovar, C., Zhu, Y., Santibanez, J., Min, W., Hale, W., Kalra, D., Getz, G., Lawrence, M. S., Sougnez, C., Carter, S. L., Sivachenko, A., Lee, L., Stewart, C., Voet, D., Fisher, S., Gabriel, S. B., Lander, E., Schumacher, S. E., Tabak, B., Saksena, G., Onofrio, R. C., Cherniack, A. D., Gentry, J., Ardlie, K., Meyerson, M., Chun, H. J. E., Mungall, A. J., Sipahimalani, P., Stoll, D., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chuah, E., Coope, R. J. N., Dhalla, N., Gorski, S., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lebovitz, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Pleasance, E., Plettner, P., Schein, J. E., Shafiei, A., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Auman, J. T., Tan, D., Jones, C. D., Hoadley, K. A., Mieczkowski, P. A., Mose, L. E., Jefferys, S. R., Topal, M. D., Liquori, C., Turman, Y. J., Yan, S., Waring, S., Buda, E., Walsh, J., Wu, J., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Kucherlapati, R., Park, P., Triche, T., Weisenberger, D. J., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Mahurkar, S., Berman, B. P., Van Den Berg, D. J., Cope, L., Baylin, S. B., Noble, M. S., DiCara, D., Zhang, H., Cho, J., Heiman, D. I., Gehlenborg, N., Mallard, W., Pei, L., Frazer, S., Stojanov, P., Liu, Y., Zhou, L., Kim, J., Chin, L., Benz, C., Yau, C., Reynolds, S. M., Shmulevich, I., Vegesna, R., Kim, H., Wei, Z., Cogdell, D., Jonasch, E., Ding, Z., Lu, Y., Zhang, N., Unruh, A. K., Casasent, T. D., Wakefield, C., Tsavachidou, D., Mills, G. B., Gao, J., Cerami, E., Gross, B., Aksoy, B. A., Sinha, R., Weinhold, N., Sumer, S. O., Taylor, B. S., Shen, R., Ostrovnaya, I., Berger, M. F., Ladanyi, M., Sander, C., Fei, S. S., Stout, A., Spellman, P. T., Rubin, D. L., Liu, T. T., Sam, N., Paull, E. O., Carlin, D., Goldstein, T., Waltman, P., Ellrott, K., Jing, Z., Haussler, D., Xiao, W., Shelton, C., Gardner, J., Penny, R., Sherman, M., Mallery, D., Morris, S., Paulauskis, J., Burnett, K., Shelton, T., Kaelin, W. G., Choueiri, T., Atkins, M. B., Curley, E., Tickoo, S., Thorne, L., Boice, L., Mei, H., Fisher, J. C., Vocke, C. D., Peterson, J., Worrell, R., Merino, M. J., Schmidt, L. S., Czerniak, B. A., Aldape, K. D., Wood, C. G., Boyd, J., Weaver, J. E., Iacocca, M. V., Petrelli, N., Witkin, G., Brown, J., Czerwinski, C., Huelsenbeck-Dill, L., Rabeno, B., Myers, J., Morrison, C., Bergsten, J., Eckman, J., Harr, J., Smith, C., Tucker, K., Zach, L. A., Bshara, W., Gaudioso, C., Dhir, R., Maranchie, J., Nelson, J., Parwani, A., Potapova, C. O., Fedosenko, K., Cheville, J. C., Thompson, R. H., Mosquera, J. M., Rubin, M. A., Blute, M. L., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Davidsen, T., Wang, Z., Yang, L., Tarnuzzer, R. W., Zhang, J., Eley, G., Ferguson, M. L., Mills Shaw, K. R., Guyer, M. S., Ozenberger, B. A. & Sofia, H. J., 2013, In: Nature. 499, 7456, p. 43-49 7 p.

    Research output: Contribution to journalArticlepeer-review

    1932 Scopus citations
  • GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

    Pharoah, P. D. P., Tsai, Y. Y., Ramus, S. J., Phelan, C. M., Goode, E. L., Lawrenson, K., Buckley, M., Fridley, B. L., Tyrer, J. P., Shen, H., Weber, R., Karevan, R., Larson, M. C., Song, H., Tessier, D. C., Bacot, F., Vincent, D., Cunningham, J. M., Dennis, J., Dicks, E. & 148 others, Aben, K. K., Anton-Culver, H., Antonenkova, N., Armasu, S. M., Baglietto, L., Bandera, E. V., Beckmann, M. W., Birrer, M. J., Bloom, G., Bogdanova, N., Brenton, J. D., Brinton, L. A., Brooks-Wilson, A., Brown, R., Butzow, R., Campbell, I., Carney, M. E., Carvalho, R. S., Chang-Claude, J., Chen, Y. A., Chen, Z., Chow, W. H., Cicek, M. S., Coetzee, G., Cook, L. S., Cramer, D. W., Cybulski, C., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J. A., Dörk, T., Du Bois, A., Dürst, M., Eccles, D., Edwards, R., Ekici, A. B., Fasching, P. A., Fenstermacher, D., Flanagan, J., Gao, Y. T., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G., Gjyshi, A., Gore, M., Gronwald, J., Guo, Q., Halle, M. K., Harter, P., Hein, A., Heitz, F., Hillemanns, P., Hoatlin, M., Høgdall, E., Høgdall, C. K., Hosono, S., Jakubowska, A., Jensen, A., Kalli, K. R., Karlan, B. Y., Kelemen, L. E., Kiemeney, L. A., Kjaer, S. K., Konecny, G. E., Krakstad, C., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Le, N. D., Lee, N., Lee, J., Leminen, A., Lim, B. K., Lissowska, J., Lubiński, J., Lundvall, L., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S., Orlow, I., Paul, J., Pejovic, T., Pelttari, L. M., Permuth-Wey, J., Pike, M. C., Poole, E. M., Qu, X., Risch, H. A., Rodriguez-Rodriguez, L., Rossing, M. A., Rudolph, A., Runnebaum, I., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shen, H., Shridhar, V., Shu, X. O., Sieh, W., Southey, M. C., Spellman, P., Tajima, K., Teo, S. H., Terry, K. L., Thompson, P. J., Timorek, A., Tworoger, S. S., Van Altena, A. M., Van Den Berg, D., Vergote, I., Vierkant, R. A., Vitonis, A. F., Wang-Gohrke, S., Wentzensen, N., Whittemore, A. S., Wik, E., Winterhoff, B., Woo, Y. L., Wu, A. H., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Goodman, M. T., Hall, P., Easton, D. F., Pearce, C. L., Berchuck, A., Chenevix-Trench, G., Iversen, E., Monteiro, A. N. A., Gayther, S. A., Schildkraut, J. M. & Sellers, T. A., Apr 2013, In: Nature genetics. 45, 4, p. 362-370 9 p.

    Research output: Contribution to journalArticlepeer-review

    254 Scopus citations
  • HER-2 gene amplification in human breast cancer without concurrent HER-2 over-expression

    Luoh, S. W., Ramsey, B., Newell, A. H., Troxell, M., Hu, Z., Chin, K., Spellman, P., Olson, S. & Keenan, E., 2013, In: SpringerPlus. 2, 1, p. 1-10 10 p., 386.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer

    Rhee, J. K., Kim, K., Chae, H., Evans, J., Yan, P., Zhang, B. T., Gray, J., Spellman, P., Huang, T. H. M., Nephew, K. P. & Kim, S., Oct 2013, In: Nucleic acids research. 41, 18, p. 8464-8474 11 p.

    Research output: Contribution to journalArticlepeer-review

    47 Scopus citations
  • Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association

    Chang, H., Han, J., Borowsky, A., Loss, L., Gray, J. W., Spellman, P. T. & Parvin, B., 2013, In: IEEE Transactions on Medical Imaging. 32, 4, p. 670-682 13 p., 6374258.

    Research output: Contribution to journalArticlepeer-review

    74 Scopus citations
  • Methods and challenges in timing chromosomal abnormalities within cancer samples

    Purdom, E., Ho, C., Grasso, C. S., Quist, M. J., Cho, R. J., Spellman, P. & Kelso, J., Dec 15 2013, In: Bioinformatics. 29, 24, p. 3113-3120 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    17 Scopus citations
  • Modeling precision treatment of breast cancer

    Daemen, A., Griffith, O. L., Heiser, L. M., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J. E., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R. & 7 others, Lu, Y., Mills, G. B., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. T. & Gray, J. W., Dec 10 2013, In: Genome biology. 14, 10, R110.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    169 Scopus citations
  • Phospholipid Scramblase 1, an interferon-regulated gene located at 3q23, is regulated by SnoN/SkiL in ovarian cancer cells

    Kodigepalli, K. M., Anur, P., Spellman, P., Sims, P. J. & Nanjundan, M., Apr 26 2013, In: Molecular Cancer. 12, 1, 32.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

    Verhaak, R. G. W., Tamayo, P., Yang, J. Y., Hubbard, D., Zhang, H., Creighton, C. J., Fereday, S., Lawrence, M., Carter, S. L., Mermel, C. H., Kostic, A. D., Etemadmoghadam, D., Saksena, G., Cibulskis, K., Duraisamy, S., Levanon, K., Sougnez, C., Tsherniak, A., Gomez, S., Onofrio, R. & 21 others, Gabriel, S., Chin, L., Zhang, N., Spellman, P. T., Zhang, Y., Akbani, R., Hoadley, K. A., Kahn, A., Köbel, M., Huntsman, D., Soslow, R. A., Defazio, A., Birrer, M. J., Gray, J. W., Weinstein, J. N., Bowtell, D. D., Drapkin, R., Mesirov, J. P., Getz, G., Levine, D. A. & Meyerson, M., Jan 2 2013, In: Journal of Clinical Investigation. 123, 1, p. 517-525 9 p.

    Research output: Contribution to journalArticlepeer-review

    366 Scopus citations
  • The cancer genome atlas pan-cancer analysis project

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    Research output: Contribution to journalArticlepeer-review

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  • The somatic genomic landscape of glioblastoma

    TCGA Research Network, Oct 10 2013, In: Cell. 155, 2, p. 462 1 p.

    Research output: Contribution to journalArticlepeer-review

    2466 Scopus citations