Paul Spellman

Professor

  • 66935 Citations
  • 61 h-Index
1992 …2021
If you made any changes in Pure, your changes will be visible here soon.

Research Output 1998 2019

2017
5 Citations (Scopus)

ΔN-ASPP2, a novel isoform of the ASPP2 tumor suppressor, promotes cellular survival

Van Hook, K., Wang, Z., Chen, D., Nold, C., Zhu, Z., Anur, P., Lee, H. J., Yu, Z., Sheppard, B., Dai, M., Sears, R., Spellman, P. & Lopez, C., Jan 22 2017, In : Biochemical and Biophysical Research Communications. 482, 4, p. 1271-1277 7 p.

Research output: Contribution to journalArticle

p53 Genes
DNA Damage
Tumors
Protein Isoforms
Apoptosis
2016
1 Citation (Scopus)

ARTIK-52 induces replication-dependent DNA damage and p53 activation exclusively in cells of prostate and breast cancer origin

Fleyshman, D., Cheney, P., Ströse, A., Mudambi, S., Safina, A., Commane, M., Purmal, A., Morgan, K., Wang, N. J., Gray, J., Spellman, P., Issaeva, N. & Gurova, K., Feb 1 2016, In : Cell Cycle. 15, 3, p. 455-470 16 p.

Research output: Contribution to journalArticle

Androgen Receptors
DNA Damage
Prostatic Neoplasms
Breast Neoplasms
Androgens
381 Citations (Scopus)

Comprehensive Molecular Characterization of Papillary Renal-Cell Carcinoma

Linehan, W. M., Spellman, P., Ricketts, C. J., Creighton, C. J., Fei, S. S., Davis, C., Wheeler, D. A., Murray, B. A., Schmidt, L., Vocke, C. D., Peto, M., Al Mamun, A. A. M., Shinbrot, E., Sethi, A., Brooks, S., Rathmell, W. K., Brooks, A. N., Hoadley, K. A., Robertson, A. G., Brooks, D. & 208 others, Bowlby, R., Sadeghi, S., Shen, H., Weisenberger, D. J., Bootwalla, M., Baylin, S. B., Laird, P. W., Cherniack, A. D., Saksena, G., Haake, S., Li, J., Liang, H., Lu, Y., Mills, G., Akbani, R., Leiserson, M. D. M., Raphael, B. J., Anur, P., Bottaro, D., Albiges, L., Barnabas, N., Choueiri, T. K., Czerniak, B., Godwin, A. K., Hakimi, A. A., Ho, T. H., Hsieh, J., Ittmann, M., Kim, W. Y., Krishnan, B., Merino, M. J., Shaw, K. R. M., Reuter, V. E., Reznik, E., Shelley, C. S., Shuch, B., Signoretti, S., Srinivasan, R., Tamboli, P., Thomas, G., Tickoo, S., Burnett, K., Crain, D., Gardner, J., Lau, K., Mallery, D., Morris, S., Paulauskis, J. D., Penny, R. J., Shelton, C., Shelton, W. T., Sherman, M., Thompson, E., Yena, P., Avedon, M. T., Bowen, J., Gastier-Foster, J. M., Gerken, M., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Santos, T., Wise, L., Zmuda, E., Demchok, J. A., Felau, I., Hutter, C. M., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zenklusen, J. C., Zhang, J., Ayala, B., Baboud, J., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Ally, A., Balasundaram, M., Balu, S., Beroukhim, R., Bodenheimer, T., Buhay, C., Butterfield, Y. S. N., Carlsen, R., Carter, S. L., Chao, H., Chuah, E., Clarke, A., Covington, K. R., Dahdouli, M., Dewal, N., Dhalla, N., Doddapaneni, H. V., Drummond, J. A., Gabriel, S. B., Gibbs, R. A., Guin, R., Hale, W., Hawes, A., Hayes, D. N., Holt, R. A., Hoyle, A. P., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kalra, D., Kovar, C., Lewis, L., Li, J., Ma, Y., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Morton, D., Mose, L. E., Mungall, A. J., Muzny, D., Parker, J. S., Perou, C. M., Roach, J., Schein, J. E., Schumacher, S. E., Shi, Y., Simons, J. V., Sipahimalani, P., Skelly, T., Soloway, M. G., Sougnez, C., Tam, A., Tan, D., Thiessen, N., Veluvolu, U., Wang, M., Wilkerson, M. D., Wong, T., Wu, J., Xi, L., Zhou, J., Bedford, J., Chen, F., Fu, Y., Gerstein, M., Haussler, D., Kasaian, K., Lai, P., Ling, S., Radenbaugh, A., Van Den Berg, D., Weinstein, J. N., Zhu, J., Albert, M., Alexopoulou, I., Andersen, J. J., Auman, J. T., Bartlett, J., Bastacky, S., Bergsten, J., Blute, M. L., Boice, L., Bollag, R. J., Boyd, J., Castle, E., Chen, Y. B., Cheville, J. C., Curley, E., Davies, B., DeVolk, A., Dhir, R., Dike, L., Eckman, J., Engel, J., Harr, J., Hrebinko, R., Huang, M., Huelsenbeck-Dill, L., Iacocca, M., Jacobs, B., Lobis, M., Maranchie, J. K., McMeekin, S., Myers, J., Nelson, J., Parfitt, J., Parwani, A., Petrelli, N., Rabeno, B., Roy, S., Salner, A. L., Slaton, J., Stanton, M., Thompson, R. H., Thorne, L., Tucker, K., Weinberger, P. M., Winemiller, C., Zach, L. A. & Zuna, R., Jan 14 2016, In : New England Journal of Medicine. 374, 2, p. 135-145 11 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Antioxidant Response Elements
CpG Islands
Kidney Neoplasms
Phenotype
36 Citations (Scopus)

FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer

Fu, X., Jeselsohn, R., Pereira, R., Hollingsworth, E. F., Creighton, C. J., Li, F., Shea, M., Nardone, A., De Angelis, C., Heiser, L., Anur, P., Wang, N., Grasso, C. S., Spellman, P., Griffith, O. L., Tsimelzon, A., Gutierrez, C., Huang, S., Edwards, D. P., Trivedi, M. V. & 7 others, Rimawi, M. F., Lopez-Terrada, D., Hilsenbeck, S. G., Gray, J., Brown, M., Osborne, C. K. & Schiff, R., Oct 25 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 43, p. E6600-E6609

Research output: Contribution to journalArticle

Interleukin-8
Transcriptome
Estrogen Receptors
Breast Neoplasms
Hepatocyte Nuclear Factor 3-alpha
5 Citations (Scopus)

Genome co-amplification upregulates a mitotic gene network activity that predicts outcome and response to mitotic protein inhibitors in breast cancer

Hu, Z., Mao, J. H., Curtis, C., Huang, G., Gu, S., Heiser, L., Lenburg, M. E., Korkola, J., Bayani, N., Samarajiwa, S., Seoane, J. A., Dane, M., Esch, A., Feiler, H., Wang, N. J., Hardwicke, M. A., Laquerre, S., Jackson, J., Wood, K., Weber, B. & 5 others, Spellman, P., Aparicio, S., Wooster, R., Caldas, C. & Gray, J., Jul 1 2016, In : Breast Cancer Research. 18, 1, 70.

Research output: Contribution to journalArticle

Spindle Apparatus
Gene Regulatory Networks
Up-Regulation
Genome
Breast Neoplasms
23 Citations (Scopus)

Identification of shared TCR sequences from T cells in human breast cancer Using emulsion RT-PCR

Munson, D. J., Egelston, C. A., Chiotti, K. E., Parra, Z. E., Bruno, T. C., Moore, B. L., Nakano, T. A., Simons, D. L., Jimenez, G., Yim, J. H., Rozanov, D., Falta, M. T., Fontenot, A. P., Reynolds, P. R., Leach, S. M., Borges, V. F., Kappler, J. W., Spellman, P., Lee, P. P. & Slansky, J. E., Jul 19 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 29, p. 8272-8277 6 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
Emulsions
Breast Neoplasms
T-Lymphocytes
Polymerase Chain Reaction
81 Citations (Scopus)

Inferring causal molecular networks: Empirical assessment through a community-based effort

Hill, S. M., Heiser, L., Cokelaer, T., Unger, M., Nesser, N. K., Carlin, D. E., Zhang, Y., Sokolov, A., Paull, E. O., Wong, C. K., Graim, K., Bivol, A., Wang, H., Zhu, F., Afsari, B., Danilova, L. V., Favorov, A. V., Lee, W. S., Taylor, D., Hu, C. W. & 18 others, Long, B. L., Noren, D. P., Bisberg, A. J., Mills, G., Gray, J., Kellen, M., Norman, T., Friend, S., Qutub, A. A., Fertig, E. J., Guan, Y., Song, M., Stuart, J. M., Spellman, P., Koeppl, H., Stolovitzky, G., Saez-Rodriguez, J. & Mukherjee, S., Mar 30 2016, In : Nature Methods. 13, 4, p. 310-318 9 p.

Research output: Contribution to journalArticle

Phosphoproteins
Learning
Nonlinear Dynamics
Computer Simulation
Visualization
12 Citations (Scopus)

Patient-specific factors influence somatic variation patterns in von Hippel-Lindau disease renal tumours

Fei, S. S., Mitchell, A. D., Heskett, M. B., Vocke, C. D., Ricketts, C. J., Peto, M., Wang, N. J., Sonmez, M. K., Linehan, W. M. & Spellman, P., May 13 2016, In : Nature Communications. 7, 11588.

Research output: Contribution to journalArticle

von Hippel-Lindau Disease
Tumors
tumors
Kidney
Neoplasms
2015
115 Citations (Scopus)

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

Alioto, T. S., Buchhalter, I., Derdak, S., Hutter, B., Eldridge, M. D., Hovig, E., Heisler, L. E., Beck, T. A., Simpson, J. T., Tonon, L., Sertier, A. S., Patch, A. M., Jäger, N., Ginsbach, P., Drews, R., Paramasivam, N., Kabbe, R., Chotewutmontri, S., Diessl, N., Previti, C. & 63 others, Schmidt, S., Brors, B., Feuerbach, L., Heinold, M., Gröbner, S., Korshunov, A., Tarpey, P. S., Butler, A. P., Hinton, J., Jones, D., Menzies, A., Raine, K., Shepherd, R., Stebbings, L., Teague, J. W., Ribeca, P., Giner, F. C., Beltran, S., Raineri, E., Dabad, M., Heath, S. C., Gut, M., Denroche, R. E., Harding, N. J., Yamaguchi, T. N., Fujimoto, A., Nakagawa, H., Quesada, V., Valdés-Mas, R., Nakken, S., Vodák, D., Bower, L., Lynch, A. G., Anderson, C. L., Waddell, N., Pearson, J. V., Grimmond, S. M., Peto, M., Spellman, P., He, M., Kandoth, C., Lee, S., Zhang, J., Létourneau, L., Ma, S., Seth, S., Torrents, D., Xi, L., Wheeler, D. A., López-Otín, C., Campo, E., Campbell, P. J., Boutros, P. C., Puente, X. S., Gerhard, D. S., Pfister, S. M., McPherson, J. D., Hudson, T. J., Schlesner, M., Lichter, P., Eils, R., Jones, D. T. W. & Gut, I. G., Dec 9 2015, In : Nature Communications. 6, 10001.

Research output: Contribution to journalArticle

sequencing
genome
mutations
Genes
cancer
2 Citations (Scopus)

A humanized leucine zipper-TRAIL hybrid induces apoptosis of tumors both in vitro and in vivo

Rozanov, D., Spellman, P., Savinov, A. & Strongin, A. Y., Apr 7 2015, In : PLoS One. 10, 4, e0122980.

Research output: Contribution to journalArticle

Leucine Zippers
leucine zipper
Tumors
apoptosis
Apoptosis
21 Citations (Scopus)

Association of somatic mutations of ADAMTS genes with chemotherapy sensitivity and survival in high-grade serous ovarian carcinoma

Liu, Y., Yasukawa, M., Chen, K., Hu, L., Broaddus, R. R., Ding, L., Mardis, E. R., Spellman, P., Levine, D. A., Mills, G., Shmulevich, I., Sood, A. K. & Zhang, W., 2015, In : JAMA oncology. 1, 4, p. 486-494 9 p.

Research output: Contribution to journalArticle

Carcinoma
Drug Therapy
Mutation
Survival
Ovarian Neoplasms

Colon and ovarian translocations

Spellman, P., Jan 1 2015, Chromosomal Translocations and Genome Rearrangements in Cancer. Springer International Publishing, p. 417-426 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tumors
Colon
Genes
Neoplasms
Genome
10 Citations (Scopus)

Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

Korkola, J., Collisson, E. A., Heiser, L., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N. J., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Feiler, H., Lu, Y., Mills, G., Spellman, P., Tomlin, C. & 3 others, Mukherjee, S., Gray, J. & Jakkula, L., Jul 16 2015, In : PLoS One. 10, 7, e0133219.

Research output: Contribution to journalArticle

phosphatidylinositol 3-kinase
Phosphatidylinositol 3-Kinases
breast neoplasms
Breast Neoplasms
mutation
21 Citations (Scopus)

Erratum: Functionally defined therapeutic targets in diffuse intrinsic pontine glioma(Nature Medicine (2015) 21 (555-559) DOI: 10.1038/nm.3855)

Grasso, C. S., Tang, Y., Truffaux, N., Berlow, N. E., Liu, L., Debily, M. A., Quist, M. J., Davis, L., Huang, E. C., Woo, P. J., Ponnuswami, A., Chen, S., Johung, T. B., Sun, W., Kogiso, M., Du, Y., Qi, L., Huang, Y., Hütt-Cabezas, M., Warren, K. E. & 20 others, Le Dret, L., Meltzer, P. S., Mao, H., Quezado, M., Van Vuurden, D. G., Abraham, J., Fouladi, M., Svalina, M. N., Wang, N., Hawkins, C., Nazarian, J., Alonso, M. M., Raabe, E. H., Hulleman, E., Spellman, P., Li, X. N., Keller, C., Pal, R., Grill, J. & Monje, M., Jul 7 2015, In : Nature Medicine. 21, 7, p. 827 1 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Erratum to Modeling precision treatment of breast cancer [Genome Biology, 14, (2013), R110]

Daemen, A., Griffith, O. L., Heiser, L., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R. & 7 others, Lu, Y., Mills, G., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. & Gray, J., May 12 2015, In : Genome Biology. 16, 1, 95.

Research output: Contribution to journalArticle

breast neoplasms
cancer
genome
Genome
Breast Neoplasms
56 Citations (Scopus)

Exome sequencing of cell-free DNA from metastatic cancer patients identifies clinically actionable mutations distinct from primary disease

Butler, T. M., Johnson-Camacho, K., Peto, M., Wang, N. J., Macey, T. A., Korkola, J., Koppie, T., Corless, C., Gray, J. & Spellman, P., Aug 28 2015, In : PLoS One. 10, 8, e0136407.

Research output: Contribution to journalArticle

Exome
Tumors
mutation
Mutation
neoplasms
190 Citations (Scopus)

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma

Grasso, C. S., Tang, Y., Truffaux, N., Berlow, N. E., Liu, L., Debily, M. A., Quist, M. J., Davis, L., Huang, E. C., Woo, P. J., Ponnuswami, A., Chen, S., Johung, T. B., Sun, W., Kogiso, M., Du, Y., Qi, L., Huang, Y., Hütt-Cabezas, M., Warren, K. E. & 20 others, Le Dret, L., Meltzer, P. S., Mao, H., Quezado, M., Van Vuurden, D. G., Abraham, J., Fouladi, M., Svalina, M. N., Wang, N., Hawkins, C., Nazarian, J., Alonso, M. M., Raabe, E. H., Hulleman, E., Spellman, P., Li, X. N., Keller, C., Pal, R., Grill, J. & Monje, M., May 4 2015, In : Nature Medicine. 21, 6, p. 555-559 5 p.

Research output: Contribution to journalArticle

Glioma
Histone Demethylases
Histone Deacetylase Inhibitors
Heterografts
RNA
29 Citations (Scopus)

Non-random fragmentation patterns in circulating cell-free DNA reflect epigenetic regulation

Ivanov, M., Baranova, A., Butler, T., Spellman, P. & Mileyko, V., Dec 16 2015, In : BMC Genomics. 16, 13, S1.

Research output: Contribution to journalArticle

Epigenomics
DNA
Genes
Transcription Initiation Site
DNA Fragmentation
57 Citations (Scopus)

Phylogenetic analyses of melanoma reveal complex patterns of metastatic dissemination

Sanborn, J. Z., Chung, J., Purdom, E., Wang, N. J., Kakavand, H., Wilmott, J. S., Butler, T., Thompson, J. F., Mann, G. J., Haydu, L. E., Saw, R. P. M., Busam, K. J., Lo, R. S., Collisson, E. A., Hur, J. S., Spellman, P., Cleaver, J. E., Gray, J., Huh, N., Murali, R. & 3 others, Scolyer, R. A., Bastian, B. C. & Cho, R. J., Sep 1 2015, In : Proceedings of the National Academy of Sciences of the United States of America. 112, 35, p. 10995-11000 6 p.

Research output: Contribution to journalArticle

Melanoma
Neoplasm Metastasis
Neoplasms
Virus Integration
Exome

Predictive sparse morphometric context for classification of histology sections

Chang, H., Spellman, P. & Parvin, B., Jul 21 2015, Proceedings - International Symposium on Biomedical Imaging. IEEE Computer Society, Vol. 2015-July. p. 1004-1007 4 p. 7164040

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Histology
Tumors
Glossaries
Scalability
Neoplasms
12 Citations (Scopus)

Src and STAT3 inhibitors synergize to promote tumor inhibition in renal cell carcinoma

Lue, H. W., Cole, B., Rao, S. A. M., Podolak, J., Van Gaest, A., King, C., Eide, C. A., Wilmot, B., Xue, C., Spellman, P., Heiser, L., Tyner, J. & Thomas, G., 2015, In : Oncotarget. 6, 42, p. 44675-44687 13 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Neoplasms
Cell Survival
Cell Proliferation
Organ Size
11 Citations (Scopus)

Stacked Predictive Sparse Decomposition for Classification of Histology Sections

Chang, H., Zhou, Y., Borowsky, A., Barner, K., Spellman, P. & Parvin, B., May 1 2015, In : International Journal of Computer Vision. 113, 1, p. 3-18 16 p.

Research output: Contribution to journalArticle

Histology
Decomposition
Tumors
Nuclear properties
Glossaries
4 Citations (Scopus)

TRAIL-based high throughput screening reveals a link between TRAIL-mediated apoptosis and glutathione reductase, a key component of oxidative stress response

Rozanov, D., Cheltsov, A., Sergienko, E., Vasile, S., Golubkov, V., Aleshin, A. E., Levin, T., Traer, E., Hann, B., Freimuth, J., Alexeev, N., Alekseyev, M. A., Budko, S. P., Ba¨chinger, H. P. & Spellman, P., Jun 15 2015, In : PLoS One. 10, 6, e0129566.

Research output: Contribution to journalArticle

Oxidative stress
Glutathione Reductase
glutathione-disulfide reductase
stress response
Screening
2014
61 Citations (Scopus)

Classification of histology sections via multispectral convolutional sparse coding

Zhou, Y., Chang, H., Barner, K., Spellman, P. & Parvin, B., Sep 24 2014, Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition. IEEE Computer Society, p. 3081-3088 8 p. 6909790

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Histology
Filter banks
Convolution
Tumors
Microscopes
1835 Citations (Scopus)

Comprehensive molecular profiling of lung adenocarcinoma: The cancer genome atlas research network

Collisson, E. A., Campbell, J. D., Brooks, A. N., Berger, A. H., Lee, W., Chmielecki, J., Beer, D. G., Cope, L., Creighton, C. J., Danilova, L., Ding, L., Getz, G., Hammerman, P. S., Hayes, D. N., Hernandez, B., Herman, J. G., Heymach, J. V., Jurisica, I., Kucherlapati, R., Kwiatkowski, D. & 290 others, Ladanyi, M., Robertson, G., Schultz, N., Shen, R., Sinha, R., Sougnez, C., Tsao, M. S., Travis, W. D., Weinstein, J. N., Wigle, D. A., Wilkerson, M. D., Chu, A., Cherniack, A. D., Hadjipanayis, A., Rosenberg, M., Weisenberger, D. J., Laird, P. W., Radenbaugh, A., Ma, S., Stuart, J. M., Byers, L. A., Baylin, S. B., Govindan, R., Meyerson, M., Gabriel, S. B., Cibulskis, K., Kim, J., Stewart, C., Lichtenstein, L., Lander, E. S., Lawrence, M. S., Getz, E., Fulton, R., Fulton, L. L., McLellan, M. D., Wilson, R. K., Ye, K., Fronick, C. C., Maher, C. A., Miller, C. A., Wendl, M. C., Cabanski, C., Mardis, E., Wheeler, D., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Chuah, E., Dhalla, N., Guin, R., Hirst, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Varhol, R., Robertson, A. G., Wye, N., Thiessen, N., Holt, R. A., Jones, S. J. M., Marra, M. A., Imielinski, M., Onofrio, R. C., Hodis, E., Zack, T., Helman, E., Pedamallu, C. S., Mesirov, J., Saksena, G., Schumacher, S. E., Carter, S. L., Garraway, L., Beroukhim, R., Lee, S., Mahadeshwar, H. S., Pantazi, A., Protopopov, A., Ren, X., Seth, S., Song, X., Tang, J., Yang, L., Zhang, J., Chen, P. C., Parfenov, M., Xu, A. W., Santoso, N., Chin, L., Park, P. J., Hoadley, K. A., Auman, J. T., Meng, S., Shi, Y., Buda, E., Waring, S., Veluvolu, U., Tan, D., Mieczkowski, P. A., Jones, C. D., Simons, J. V., Soloway, M. G., Bodenheimer, T., Jefferys, S. R., Roach, J., Hoyle, A. P., Wu, J., Balu, S., Singh, D., Prins, J. F., Marron, J. S., Parker, J. S., Perou, C. M., Liu, J., Maglinte, D. T., Lai, P. H., Bootwalla, M. S., Van Den Berg, D. J., Triche, T., Cho, J., DiCara, D., Heiman, D., Lin, P., Mallard, W., Voet, D., Zhang, H., Zou, L., Noble, M. S., Gehlenborg, N., Thorvaldsdottir, H., Nazaire, M. D., Robinson, J., Aksoy, B. A., Ciriello, G., Taylor, B. S., Dresdner, G., Gao, J., Gross, B., Seshan, V. E., Reva, B., Sumer, S. O., Weinhold, N., Sander, C., Ng, S., Zhu, J., Benz, C. C., Yau, C., Haussler, D., Spellman, P., Kimes, P. K., Broom, B. M., Wang, J., Lu, Y., Ng, P. K. S., Diao, L., Liu, W., Amos, C. I., Akbani, R., Mills, G., Curley, E., Paulauskis, J., Lau, K., Morris, S., Shelton, T., Mallery, D., Gardner, J., Penny, R., Saller, C., Tarvin, K., Richards, W. G., Cerfolio, R., Bryant, A., Raymond, D. P., Pennell, N. A., Farver, C., Czerwinski, C., Huelsenbeck-Dill, L., Iacocca, M., Petrelli, N., Rabeno, B., Brown, J., Bauer, T., Dolzhanskiy, C. O., Potapova, O., Rotin, D., Voronina, O., Nemirovich-Danchenko, E., Fedosenko, K. V., Gal, A., Behera, M., Ramalingam, S. S., Sica, G., Flieder, D., Boyd, J., Weaver, J. E., Kohl, B., Thinh, D. H. Q., Sandusky, G., Juhl, H., Duhig, E., Illei, P., Gabrielson, E., Shin, J., Lee, B., Rogers, K., Trusty, D., Brock, M. V., Williamson, C., Burks, E., Rieger-Christ, K., Holway, A., Sullivan, T., Asiedu, M. K., Kosari, F., Rekhtman, N., Zakowski, M., Rusch, V. W., Zippile, P., Suh, J., Pass, H., Goparaju, C., Owusu-Sarpong, Y., Bartlett, J. M. S., Kodeeswaran, S., Parfitt, J., Sekhon, H., Albert, M., Eckman, J., Myers, J. B., Morrison, C., Gaudioso, C., Borgia, J. A., Bonomi, P., Pool, M., Liptay, M. J., Moiseenko, F., Zaytseva, I., Dienemann, H., Meister, M., Schnabel, P. A., Muley, T. R., Peifer, M., Gomez-Fernandez, C., Herbert, L., Egea, S., Huang, M., Thorne, L. B., Boice, L., Salazar, A. H., Funkhouser, W. K., Rathmell, W. K., Dhir, R., Yousem, S. A., Dacic, S., Schneider, F., Siegfried, J. M., Hajek, R., Watson, M. A., McDonald, S., Meyers, B., Clarke, B., Yang, I. A., Fong, K. M., Hunter, L., Windsor, M., Bowman, R. V., Peters, S., Letovanec, I., Khan, K. Z., Jensen, M. A., Snyder, E. E., Srinivasan, D., Kahn, A. B., Baboud, J., Pot, D. A., Shaw, K. R. M., Sheth, M., Davidsen, T., Demchok, J. A., Yang, L., Wang, Z., Tarnuzzer, R., Zenklusen, J. C., Ozenberger, B. A., Sofia, H. J. & Cheney, R., 2014, In : Nature. 511, 7511, p. 543-550 8 p.

Research output: Contribution to journalArticle

Atlases
Genome
Mutation
Research
Neoplasms
27 Citations (Scopus)

Detecting cancer by monitoring circulating tumor DNA.

Spellman, P. & Gray, J., 2014, In : Nature Medicine. 20, 5, p. 474-475 2 p.

Research output: Contribution to journalArticle

Neoplasm DNA
Tumor Biomarkers
Non-Small Cell Lung Carcinoma
DNA
Neoplasms
8 Citations (Scopus)

Erratum: The somatic genomic landscape of glioblastoma (Cell (2013) 155 (462-477))

Brennan, C. W., Verhaak, R. G. W., McKenna, A., Campos, B., Noushmehr, H., Salama, S. R., Zheng, S., Chakravarty, D., Sanborn, J. Z., Berman, S. H., Beroukhim, R., Bernard, B., Wu, C. J., Genovese, G., Shmulevich, I., Barnholtz-Sloan, J., Zou, L., Vegesna, R., Shukla, S. A., Ciriello, G. & 38 others, Yung, W. K., Zhang, W., Sougnez, C., Mikkelsen, T., Aldape, K., Bigner, D. D., Van Meir, E. G., Prados, M., Sloan, A., Black, K. L., Eschbacher, J., Finocchiaro, G., Friedman, W., Andrews, D. W., Guha, A., Iacocca, M., O'Neill, B. P., Foltz, G., Myers, J., Weisenberger, D. J., Penny, R., Kucherlapati, R., Perou, C. M., Hayes, D. N., Gibbs, R., Marra, M., Mills, G., Lander, E., Spellman, P., Wilson, R., Sander, C., Weinstein, J., Meyerson, M., Gabriel, S., Laird, P. W., Haussler, D., Getz, G. & Chin, L., Apr 24 2014, In : Cell. 157, 3, p. 753 1 p.

Research output: Contribution to journalArticle

28 Citations (Scopus)

Global optimization of somatic variant identification in cancer genomes with a global community challenge

Boutros, P. C., Ewing, A. D., Ellrott, K., Norman, T. C., Dang, K. K., Hu, Y., Kellen, M. R., Suver, C., Bare, J. C., Stein, L. D., Spellman, P., Stolovitzky, G., Friend, S. H., Margolin, A. & Stuart, J. M., 2014, In : Nature Genetics. 46, 4, p. 318-319 2 p.

Research output: Contribution to journalArticle

DNA Mutational Analysis
Crowdsourcing
High-Throughput Screening Assays
Genetic Databases
Human Genome
117 Citations (Scopus)

Integrated analysis of germline and somatic variants in ovarian cancer

Kanchi, K. L., Johnson, K. J., Lu, C., McLellan, M. D., Leiserson, M. D. M., Wendl, M. C., Zhang, Q., Koboldt, D. C., Xie, M., Kandoth, C., McMichael, J. F., Wyczalkowski, M. A., Larson, D. E., Schmidt, H. K., Miller, C. A., Fulton, R. S., Spellman, P., Mardis, E. R., Druley, T. E., Graubert, T. A. & 4 others, Goodfellow, P. J., Raphael, B. J., Wilson, R. K. & Ding, L., Jan 22 2014, In : Nature Communications. 5, 3156.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Genes
cancer
Exome
Loss of Heterozygosity
40 Citations (Scopus)

Overcoming endocrine resistance due to reduced PTEN levels in estrogen receptor-positive breast cancer by co-targeting mammalian target of rapamycin, protein kinase B, or mitogen-activated protein kinase kinase

Fu, X., Creighton, C. J., Biswal, N. C., Kumar, V., Shea, M., Herrera, S., Contreras, A., Gutierrez, C., Wang, T., Nanda, S., Giuliano, M., Morrison, G., Nardone, A., Karlin, K. L., Westbrook, T. F., Heiser, L., Anur, P., Spellman, P., Guichard, S. M., Smith, P. D. & 10 others, Davies, B. R., Klinowska, T., Lee, A. V., Mills, G., Rimawi, M. F., Hilsenbeck, S. G., Gray, J., Joshi, A., Osborne, C. K. & Schiff, R., Sep 11 2014, In : Breast Cancer Research. 16, 5, 430.

Research output: Contribution to journalArticle

TOR Serine-Threonine Kinases
Proto-Oncogene Proteins c-akt
Mitogen-Activated Protein Kinase Kinases
Phosphatidylinositol 3-Kinase
Phosphoric Monoester Hydrolases
298 Citations (Scopus)

The somatic genomic landscape of chromophobe renal cell carcinoma

The Cancer Genome Atlas Research Network, 2014, In : Cancer Cell. 26, 3, p. 319-330 12 p.

Research output: Contribution to journalArticle

Mitochondrial DNA
Renal Cell Carcinoma
Kidney Neoplasms
Oxidative Phosphorylation
Nephrons
42 Citations (Scopus)

Transcription Restores DNA Repair to Heterochromatin, Determining Regional Mutation Rates in Cancer Genomes

Zheng, C., Wang, N. J., Chung, J., Moslehi, H., Sanborn, J. Z., Hur, J. S., Collisson, E. A., Vemula, S. S., Naujokas, A., Chiotti, K. E., Cheng, J. B., Fassihi, H., Blumberg, A. J., Bailey, C. V., Fudem, G. M., Mihm, F. G., Cunningham, B. B., Neuhaus, I. M., Liao, W., Oh, D. H. & 10 others, Cleaver, J. E., LeBoit, P. E., Costello, J. F., Lehmann, A. R., Gray, J., Spellman, P., Arron, S. T., Huh, N., Purdom, E. & Cho, R. J., Nov 20 2014, In : Cell Reports. 9, 4, p. 1228-1234 7 p.

Research output: Contribution to journalArticle

Heterochromatin
Mutation Rate
Transcription
DNA Repair
Repair

Understanding and Using Information about Cancer Genomes

Spellman, P., Stuart, J. & Gray, J., Mar 2014, The Molecular Basis of Cancer: Fourth Edition. Elsevier Inc.

Research output: Chapter in Book/Report/Conference proceedingChapter

Genome
Neoplasms
2013
10 Citations (Scopus)

A robust prognostic signature for hormone-positive node-negative breast cancer

Griffith, O. L., Pepin, F., Enache, O. M., Heiser, L., Collisson, E. A., Spellman, P. & Gray, J., Oct 11 2013, In : Genome Medicine. 5, 10, 92.

Research output: Contribution to journalArticle

Hormones
Breast Neoplasms
Recurrence
Genes
Survival Analysis

Characterization of tissue histopathology via predictive sparse decomposition and spatial pyramid matching

Chang, H., Nayak, N., Spellman, P. & Parvin, B., 2013, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). PART 2 ed. Vol. 8150 LNCS. p. 91-98 8 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8150 LNCS, no. PART 2).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Histology
Pyramid
Tumors
Tumor
Tissue
26 Citations (Scopus)

Characterization of tissue histopathology via predictive sparse decomposition and spatial pyramid matching.

Chang, H., Nayak, N., Spellman, P. & Parvin, B., 2013, Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. Pt 2 ed. Vol. 16. p. 91-98 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Histology
Neoplasms
Atlases
Sample Size
Genome
24 Citations (Scopus)

Classification of tumor histology via morphometric context

Chang, H., Borowsky, A., Spellman, P. & Parvin, B., 2013, Proceedings of the IEEE Computer Society Conference on Computer Vision and Pattern Recognition. p. 2203-2210 8 p. 6619130

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Histology
Tumors
Tissue
Agglomeration
Genes
12 Citations (Scopus)

Classification of tumor histopathology via sparse feature learning

Nayak, N., Chang, H., Borowsky, A., Spellman, P. & Parvin, B., 2013, Proceedings - International Symposium on Biomedical Imaging. p. 410-413 4 p. 6556499

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Glioblastoma
Tumors
Histology
Learning
Carcinoma
23 Citations (Scopus)

Classification of tumor histopathology via sparse feature learning

Nayak, N., Chang, H., Borowsky, A., Spellman, P. & Parvin, B., 2013, Proceedings - International Symposium on Biomedical Imaging. p. 1348-1351 4 p. 6556782

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Glioblastoma
Tumors
Histology
Learning
Carcinoma
1382 Citations (Scopus)

Comprehensivemolecular characterization of clear cell renal cell carcinoma

Creighton, C. J., Morgan, M., Gunaratne, P. H., Wheeler, D. A., Gibbs, R. A., Robertson, G., Chu, A., Beroukhim, R., Cibulskis, K., Signoretti, S., Vandin, F., Wu, H. T., Raphael, B. J., Verhaak, R. G. W., Tamboli, P., Torres-Garcia, W., Akbani, R., Weinstein, J. N., Reuter, V., Hsieh, J. J. & 268 others, Brannon, A. R., Hakimi, A. A., Jacobsen, A., Ciriello, G., Reva, B., Ricketts, C. J., Linehan, W. M., Stuart, J. M., Rathmell, W. K., Hui, S., Laird, P. W., Muzny, D., Davis, C., Liu, X., Chang, K., Kakkar, N., Treviño, L. R., Benton, S., Reid, J. G., Morton, D., Doddapaneni, H., Yi, H., Lewis, L., Huyen, D., Kovar, C., Zhu, Y., Santibanez, J., Min, W., Hale, W., Kalra, D., Getz, G., Lawrence, M. S., Sougnez, C., Carter, S. L., Sivachenko, A., Lee, L., Stewart, C., Voet, D., Fisher, S., Gabriel, S. B., Lander, E., Schumacher, S. E., Tabak, B., Saksena, G., Onofrio, R. C., Cherniack, A. D., Gentry, J., Ardlie, K., Meyerson, M., Chun, H. J. E., Mungall, A. J., Sipahimalani, P., Stoll, D., Ally, A., Balasundaram, M., Butterfield, Y. S. N., Carlsen, R., Carter, C., Chuah, E., Coope, R. J. N., Dhalla, N., Gorski, S., Guin, R., Hirst, C., Hirst, M., Holt, R. A., Lebovitz, C., Lee, D., Li, H. I., Mayo, M., Moore, R. A., Pleasance, E., Plettner, P., Schein, J. E., Shafiei, A., Slobodan, J. R., Tam, A., Thiessen, N., Varhol, R. J., Wye, N., Zhao, Y., Birol, I., Jones, S. J. M., Marra, M. A., Auman, J. T., Tan, D., Jones, C. D., Hoadley, K. A., Mieczkowski, P. A., Mose, L. E., Jefferys, S. R., Topal, M. D., Liquori, C., Turman, Y. J., Yan, S., Waring, S., Buda, E., Walsh, J., Wu, J., Bodenheimer, T., Hoyle, A. P., Simons, J. V., Soloway, M. G., Balu, S., Parker, J. S., Hayes, D. N., Perou, C. M., Kucherlapati, R., Park, P., Triche, T., Weisenberger, D. J., Lai, P. H., Bootwalla, M. S., Maglinte, D. T., Mahurkar, S., Berman, B. P., Van Den Berg, D. J., Cope, L., Baylin, S. B., Noble, M. S., DiCara, D., Zhang, H., Cho, J., Heiman, D. I., Gehlenborg, N., Mallard, W., Pei, L., Frazer, S., Stojanov, P., Liu, Y., Zhou, L., Kim, J., Chin, L., Benz, C., Yau, C., Reynolds, S. M., Shmulevich, I., Vegesna, R., Kim, H., Wei, Z., Cogdell, D., Jonasch, E., Ding, Z., Lu, Y., Zhang, N., Unruh, A. K., Casasent, T. D., Wakefield, C., Tsavachidou, D., Mills, G., Gao, J., Cerami, E., Gross, B., Aksoy, B. A., Sinha, R., Weinhold, N., Sumer, S. O., Taylor, B. S., Shen, R., Ostrovnaya, I., Berger, M. F., Ladanyi, M., Sander, C., Fei, S. S., Stout, A., Spellman, P., Rubin, D. L., Liu, T. T., Sam, N., Paull, E. O., Carlin, D., Goldstein, T., Waltman, P., Ellrott, K., Jing, Z., Haussler, D., Xiao, W., Shelton, C., Gardner, J., Penny, R., Sherman, M., Mallery, D., Morris, S., Paulauskis, J., Burnett, K., Shelton, T., Kaelin, W. G., Choueiri, T., Atkins, M. B., Curley, E., Tickoo, S., Thorne, L., Boice, L., Mei, H., Fisher, J. C., Vocke, C. D., Peterson, J., Worrell, R., Merino, M. J., Schmidt, L. S., Czerniak, B. A., Aldape, K. D., Wood, C. G., Boyd, J., Weaver, J. E., Iacocca, M. V., Petrelli, N., Witkin, G., Brown, J., Czerwinski, C., Huelsenbeck-Dill, L., Rabeno, B., Myers, J., Morrison, C., Bergsten, J., Eckman, J., Harr, J., Smith, C., Tucker, K., Zach, L. A., Bshara, W., Gaudioso, C., Dhir, R., Maranchie, J., Nelson, J., Parwani, A., Potapova, C. O., Fedosenko, K., Cheville, J. C., Thompson, R. H., Mosquera, J. M., Rubin, M. A., Blute, M. L., Pihl, T., Jensen, M., Sfeir, R., Kahn, A., Chu, A., Kothiyal, P., Snyder, E., Pontius, J., Ayala, B., Backus, M., Walton, J., Baboud, J., Berton, D., Nicholls, M., Srinivasan, D., Raman, R., Girshik, S., Kigonya, P., Alonso, S., Sanbhadti, R., Barletta, S., Pot, D., Sheth, M., Demchok, J. A., Davidsen, T., Wang, Z., Yang, L., Tarnuzzer, R. W., Zhang, J., Eley, G., Ferguson, M. L., Mills Shaw, K. R., Guyer, M. S., Ozenberger, B. A. & Sofia, H. J., 2013, In : Nature. 499, 7456, p. 43-49 7 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Genes
PTEN Phosphohydrolase
Acetyl-CoA Carboxylase
Pentose Phosphate Pathway
219 Citations (Scopus)

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Pharoah, P. D. P., Tsai, Y. Y., Ramus, S. J., Phelan, C. M., Goode, E. L., Lawrenson, K., Buckley, M., Fridley, B. L., Tyrer, J. P., Shen, H., Weber, R., Karevan, R., Larson, M. C., Song, H., Tessier, D. C., Bacot, F., Vincent, D., Cunningham, J. M., Dennis, J., Dicks, E. & 148 others, Aben, K. K., Anton-Culver, H., Antonenkova, N., Armasu, S. M., Baglietto, L., Bandera, E. V., Beckmann, M. W., Birrer, M. J., Bloom, G., Bogdanova, N., Brenton, J. D., Brinton, L. A., Brooks-Wilson, A., Brown, R., Butzow, R., Campbell, I., Carney, M. E., Carvalho, R. S., Chang-Claude, J., Chen, Y. A., Chen, Z., Chow, W. H., Cicek, M. S., Coetzee, G., Cook, L. S., Cramer, D. W., Cybulski, C., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J. A., Dörk, T., Du Bois, A., Dürst, M., Eccles, D., Edwards, R., Ekici, A. B., Fasching, P. A., Fenstermacher, D., Flanagan, J., Gao, Y. T., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G., Gjyshi, A., Gore, M., Gronwald, J., Guo, Q., Halle, M. K., Harter, P., Hein, A., Heitz, F., Hillemanns, P., Hoatlin, M., Høgdall, E., Høgdall, C. K., Hosono, S., Jakubowska, A., Jensen, A., Kalli, K. R., Karlan, B. Y., Kelemen, L. E., Kiemeney, L. A., Kjaer, S. K., Konecny, G. E., Krakstad, C., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Le, N. D., Lee, N., Lee, J., Leminen, A., Lim, B. K., Lissowska, J., Lubiński, J., Lundvall, L., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S., Orlow, I., Paul, J., Pejovic, T., Pelttari, L. M., Permuth-Wey, J., Pike, M. C., Poole, E. M., Qu, X., Risch, H. A., Rodriguez-Rodriguez, L., Rossing, M. A., Rudolph, A., Runnebaum, I., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shen, H., Shridhar, V., Shu, X. O., Sieh, W., Southey, M. C., Spellman, P., Tajima, K., Teo, S. H., Terry, K. L., Thompson, P. J., Timorek, A., Tworoger, S. S., Van Altena, A. M., Van Den Berg, D., Vergote, I., Vierkant, R. A., Vitonis, A. F., Wang-Gohrke, S., Wentzensen, N., Whittemore, A. S., Wik, E., Winterhoff, B., Woo, Y. L., Wu, A. H., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Goodman, M. T., Hall, P., Easton, D. F., Pearce, C. L., Berchuck, A., Chenevix-Trench, G., Iversen, E., Monteiro, A. N. A., Gayther, S. A., Schildkraut, J. M. & Sellers, T. A., Apr 2013, In : Nature Genetics. 45, 4, p. 362-370 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Ovarian Neoplasms
Meta-Analysis
Genome
Nucleic Acid Regulatory Sequences
11 Citations (Scopus)

HER-2 gene amplification in human breast cancer without concurrent HER-2 over-expression

Luoh, S-W., Ramsey, B., Newell, A. H., Troxell, M., Hu, Z., Chin, K-Y., Spellman, P., Olson, S. & Keenan, E., 2013, In : SpringerPlus. 2, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

erbB-1 Genes
Gene Amplification
Breast Neoplasms
GRB7 Adaptor Protein
Proteins
42 Citations (Scopus)

Integrated analysis of genome-wide DNA methylation and gene expression profiles in molecular subtypes of breast cancer

Rhee, J. K., Kim, K., Chae, H., Evans, J., Yan, P., Zhang, B. T., Gray, J., Spellman, P., Huang, T. H. M., Nephew, K. P. & Kim, S., Oct 2013, In : Nucleic Acids Research. 41, 18, p. 8464-8474 11 p.

Research output: Contribution to journalArticle

DNA Methylation
Transcriptome
Genome
Breast Neoplasms
Gene Expression
59 Citations (Scopus)

Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association

Chang, H., Han, J., Borowsky, A., Loss, L., Gray, J., Spellman, P. & Parvin, B., 2013, In : IEEE Transactions on Medical Imaging. 32, 4, p. 670-682 13 p., 6374258.

Research output: Contribution to journalArticle

Glioblastoma
Tumors
Tissue
Neoplasms
Bioinformatics
14 Citations (Scopus)

Methods and challenges in timing chromosomal abnormalities within cancer samples.

Purdom, E., Ho, C., Grasso, C. S., Quist, M. J., Cho, R. J. & Spellman, P., Dec 15 2013, In : Bioinformatics (Oxford, England). 29, 24, p. 3113-3120 8 p.

Research output: Contribution to journalArticle

Chromosome Aberrations
Tumors
Timing
Tumor
Cancer
126 Citations (Scopus)

Modeling precision treatment of breast cancer.

Daemen, A., Griffith, O. L., Heiser, L., Wang, N. J., Enache, O. M., Sanborn, Z., Pepin, F., Durinck, S., Korkola, J., Griffith, M., Hur, J. S., Huh, N., Chung, J., Cope, L., Fackler, M. J., Umbricht, C., Sukumar, S., Seth, P., Sukhatme, V. P., Jakkula, L. R. & 7 others, Lu, Y., Mills, G., Cho, R. J., Collisson, E. A., van't Veer, L. J., Spellman, P. & Gray, J., 2013, In : Genome Biology. 14, 10

Research output: Contribution to journalArticle

breast neoplasms
cancer
Breast Neoplasms
therapeutics
modeling

Molecular Correlates of Morphometric Subtypes in Glioblastoma Multiforme

Chang, H., Fontenay, G. V., Bilgin, C. C., Borowsky, A., Spellman, P. & Parvin, B., Dec 2013, Computational Systems Biology: From Molecular Mechanisms to Disease: Second Edition. Elsevier Inc., p. 423-454 32 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Glioblastoma
Tissue
Genes
Genome
Histology
16 Citations (Scopus)

Phospholipid Scramblase 1, an interferon-regulated gene located at 3q23, is regulated by SnoN/SkiL in ovarian cancer cells

Kodigepalli, K. M., Anur, P., Spellman, P., Sims, P. J. & Nanjundan, M., Apr 26 2013, In : Molecular Cancer. 12, 1, 32.

Research output: Contribution to journalArticle

Phospholipid Transfer Proteins
Ovarian Neoplasms
Interferons
Messenger RNA
Genes
253 Citations (Scopus)

Prognostically relevant gene signatures of high-grade serous ovarian carcinoma

Verhaak, R. G. W., Tamayo, P., Yang, J. Y., Hubbard, D., Zhang, H., Creighton, C. J., Fereday, S., Lawrence, M., Carter, S. L., Mermel, C. H., Kostic, A. D., Etemadmoghadam, D., Saksena, G., Cibulskis, K., Duraisamy, S., Levanon, K., Sougnez, C., Tsherniak, A., Gomez, S., Onofrio, R. & 21 others, Gabriel, S., Chin, L., Zhang, N., Spellman, P., Zhang, Y., Akbani, R., Hoadley, K. A., Kahn, A., Köbel, M., Huntsman, D., Soslow, R. A., Defazio, A., Birrer, M. J., Gray, J., Weinstein, J. N., Bowtell, D. D., Drapkin, R., Mesirov, J. P., Getz, G., Levine, D. A. & Meyerson, M., Jan 2 2013, In : Journal of Clinical Investigation. 123, 1, p. 517-525 9 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Carcinoma
Genes
Platinum
Survival
22 Citations (Scopus)

Stacked predictive sparse coding for classification of distinct regions in tumor histopathology

Chang, H., Zhou, Y., Spellman, P. & Parvin, B., 2013, Proceedings of the IEEE International Conference on Computer Vision. Institute of Electrical and Electronics Engineers Inc., p. 169-176 8 p. 6751130

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tumors
Histology
Cell culture
Spatial distribution
Classifiers