Patrizia Caposio

Assistant Scientist

  • 965 Citations
  • 21 h-Index
20012019

Research output per year

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Research Output

  • 965 Citations
  • 21 h-Index
  • 35 Article
  • 2 Review article
  • 1 Editorial
2019

Cancer diagnostic and predictive biomarkers 2018

Buonaguro, F. M., Caposio, P., Tornesello, M. L., De Re, V. & Franco, R., 2019, In : BioMed Research International. 2019, 3879015.

Research output: Contribution to journalEditorial

1 Scopus citations

Human Cytomegalovirus US28 ligand binding activity is required for latency in CD34+ hematopoietic progenitor cells and humanized NSG mice

Crawford, L. B., Caposio, P., Kreklywich, C., Pham, A. H., Hancock, M. H., Jones, T. A., Smith, P. P., Yurochko, A. D., Nelson, J. A. & Streblow, D. N., Jan 1 2019, In : mBio. 10, 4, e01889-19.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

OR14I1 is a receptor for the human cytomegalovirus pentameric complex and defines viral epithelial cell tropism

Xiaofei, E., Meraner, P., Lu, P., Perreira, J. M., Aker, A. M., McDougall, W. M., Zhuge, R., Chan, G. C., Gerstein, R. M., Caposio, P., Yurochko, A. D., Brass, A. L. & Kowalik, T. F., Apr 2 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7043-7052 10 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Stabilization and formulation of a recombinant Human Cytomegalovirus vector for use as a candidate HIV-1 vaccine

Kumru, O. S., Saleh-Birdjandi, S., Antunez, L. R., Sayeed, E., Robinson, D., van den Worm, S., Diemer, G. S., Perez, W., Caposio, P., Früh, K., Joshi, S. B. & Volkin, D. B., Oct 16 2019, In : Vaccine. 37, 44, p. 6696-6706 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2018

Human cytomegalovirus encodes a novel FLT3 receptor ligand necessary for hematopoietic cell differentiation and viral reactivation

Crawford, L. B., Kim, J. H., Collins-McMillen, D., Lee, B. J., Landais, I., Held, C., Nelson, J. A., Yurochko, A. D. & Caposio, P., Mar 1 2018, In : mBio. 9, 2, e00682-18.

Research output: Contribution to journalArticle

14 Scopus citations
2017

Cloning, assembly, and modification of the primary human cytomegalovirus isolate Toledo by yeast-based transformation-associated recombination

Vashee, S., Stockwell, T. B., Alperovich, N., Denisova, E. A., Gibson, D. G., Cady, K. C., Miller, K., Kannan, K., Malouli, D., Crawford, L. B., Voorhies, A. A., Bruening, E., Caposio, P. & Frueh, K., Sep 1 2017, In : mSphere. 2, 5, e00331-17.

Research output: Contribution to journalArticle

6 Scopus citations

Human cytomegalovirus induces cellular and humoral virus-specific immune responses in humanized BLT mice

Crawford, L. B., Tempel, R., Streblow, D., Kreklywich, C., Smith, P., Picker, L., Nelson, J. & Caposio, P., Dec 1 2017, In : Scientific Reports. 7, 1, 937.

Research output: Contribution to journalArticle

17 Scopus citations
2016

Complex interplay of the UL136 isoforms balances cytomegalovirus replication and Latency

Caviness, K., Bughio, F., Crawford, L. B., Streblow, D. N., Nelson, J. A., Caposio, P. & Goodrum, F., Mar 1 2016, In : mBio. 7, 2, e01986-15.

Research output: Contribution to journalArticle

22 Scopus citations
12 Scopus citations
2015

A cytomegalovirus-based vaccine provides long-lasting protection against lethal Ebola virus challenge after a single dose

Tsuda, Y., Parkins, C. J., Caposio, P., Feldmann, F., Botto, S., Ball, S., Messaoudi, I., Cicin-Sain, L., Feldmann, H. & Jarvis, M. A., Jan 1 2015, In : Vaccine. 33, 19, p. 2261-2266 6 p.

Research output: Contribution to journalArticle

33 Scopus citations

Humanized mouse models of human cytomegalovirus infection

Crawford, L. B., Streblow, D. N., Hakki, M., Nelson, J. A. & Caposio, P., Jun 29 2015, In : Current Opinion in Virology. 13, p. 86-92 7 p.

Research output: Contribution to journalReview article

23 Scopus citations
2014

Human cytomegalovirus-encoded pUL7 is a novel CEACAM1-like molecule responsible for promotion of angiogenesis

MacManiman, J. D., Meuser, A., Botto, S., Smith, P. P., Liu, F., Jarvis, M. A., Nelson, J. A. & Caposio, P., 2014, In : mBio. 5, 6, p. e02035

Research output: Contribution to journalArticle

Human cytomegalovirus-encoded pUL7 is a novel CEACAM1-like molecule responsible for promotion of angiogenesis

Macmaniman, J. D., Meuser, A., Botto, S., Smith, P. P., Liu, F., Jarvis, M. A., Nelson, J. A. & Caposio, P., Sep 26 2014, In : mBio. 5, 6, e02035-14.

Research output: Contribution to journalArticle

21 Scopus citations
2012

A cytomegalovirus-based vaccine expressing a single tumor-specific CD8 + T-cell epitope delays tumor growth in a murine model of prostate cancer

Klyushnenkova, E. N., Kouiavskaia, D. V., Parkins, C. J., Caposio, P., Botto, S., Alexander, R. B. & Jarvis, M. A., Jun 1 2012, In : Journal of Immunotherapy. 35, 5, p. 390-399 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

A single-dose cytomegalovirus-based vaccine encoding tetanus toxin fragment C induces sustained levels of protective tetanus toxin antibodies in mice

Tierney, R., Nakai, T., Parkins, C. J., Caposio, P., Fairweather, N. F., Sesardic, D. & Jarvis, M. A., Apr 26 2012, In : Vaccine. 30, 20, p. 3047-3052 6 p.

Research output: Contribution to journalArticle

15 Scopus citations
2011

A novel human cytomegalovirus locus modulates cell type-specific outcomes of infection

Umashankar, M., Petrucelli, A., Cicchini, L., Caposio, P., Kreklywich, C. N., Rak, M., Bughio, F., Goldman, D. C., Hamlin, K. L., Nelson, J. A., Fleming, W. H., Streblow, D. N. & Goodrum, F., Dec 2011, In : PLoS pathogens. 7, 12, e1002444.

Research output: Contribution to journalArticle

80 Scopus citations

A replicating cytomegalovirus-based vaccine encoding a single Ebola virus nucleoprotein CTL epitope confers protection against Ebola virus

Tsuda, Y., Caposio, P., Parkins, C. J., Botto, S., Messaoudi, I., Cicin-Sain, L., Feldmann, H. & Jarvis, M. A., Aug 2011, In : PLoS neglected tropical diseases. 5, 8, e1275.

Research output: Contribution to journalArticle

65 Scopus citations

IL-6 in human cytomegalovirus secretome promotes angiogenesis and survival of endothelial cells through the stimulation of survivin

Botto, S., Streblow, D. N., DeFilippis, V., White, L., Kreklywich, C. N., Smith, P. P. & Caposio, P., Jan 6 2011, In : Blood. 117, 1, p. 352-361 10 p.

Research output: Contribution to journalArticle

67 Scopus citations

The role of cytomegalovirus in angiogenesis

Caposio, P., Orloff, S. L. & Streblow, D. N., May 1 2011, In : Virus Research. 157, 2, p. 204-211 8 p.

Research output: Contribution to journalArticle

48 Scopus citations
2010
15 Scopus citations

The interferon-inducible gene IFI16 secretome of endothelial cells drives the early steps of the inflammatory response

Baggetta, R., De Andrea, M., Gariano, G. R., Mondini, M., Rittà, M., Caposio, P., Cappello, P., Giovarelli, M., Gariglio, M. & Landolfo, S., Aug 1 2010, In : European Journal of Immunology. 40, 8, p. 2182-2189 8 p.

Research output: Contribution to journalArticle

28 Scopus citations
2009

Fine-tuning of catalytic properties of catechol 1,2-dioxygenase by active site tailoring

Caglio, R., Valetti, F., Caposio, P., Gribaudo, G., Pessione, E. & Giunta, C., Apr 17 2009, In : ChemBioChem. 10, 6, p. 1015-1024 10 p.

Research output: Contribution to journalArticle

20 Scopus citations
2008

New cell-based indicator assays for the detection of human cytomegalovirus infection and screening of inhibitors of viral immediate-early 2 protein activity

Luganini, A., Caposio, P., Mondini, M., Landolfo, S. & Gribaudo, G., Dec 1 2008, In : Journal of Applied Microbiology. 105, 6, p. 1791-1801 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

Phosphorothioate-modified oligodeoxynucleotides inhibit human cytomegalovirus replication by blocking virus entry

Luganini, A., Caposio, P., Landolfo, S. & Gribaudo, G., Mar 2008, In : Antimicrobial agents and chemotherapy. 52, 3, p. 1111-1120 10 p.

Research output: Contribution to journalArticle

32 Scopus citations
2007

Activation of the virus-induced IKK/NF-κB signalling axis is critical for the replication of human cytomegalovirus in quiescent cells

Caposio, P., Luganini, A., Hahn, G., Landolfo, S. & Gribaudo, G., Aug 1 2007, In : Cellular Microbiology. 9, 8, p. 2040-2054 15 p.

Research output: Contribution to journalArticle

37 Scopus citations

A novel role of the interferon-inducible protein IFI16 as inducer of proinflammatory molecules in endothelial cells

Caposio, P., Gugliesi, F., Zannetti, C., Sponza, S., Mondini, M., Medico, E., Hiscott, J., Young, H. A., Gribaudo, G., Gariglio, M. & Landolfo, S., Nov 16 2007, In : Journal of Biological Chemistry. 282, 46, p. 33515-33529 15 p.

Research output: Contribution to journalArticle

51 Scopus citations

Imbalance between activin A and follistatin drives postburn hypertrophic scar formation in human skin

Fumagalli, M., Musso, T., Vermi, W., Scutera, S., Daniele, R., Alotto, D., Cambieri, I., Ostorero, A., Gentili, F., Caposio, P., Zucca, M., Sozzani, S., Stella, M. & Castagnoli, C., Jul 1 2007, In : Experimental Dermatology. 16, 7, p. 600-610 11 p.

Research output: Contribution to journalArticle

41 Scopus citations

Targeting the NF-κB pathway through pharmacological inhibition of IKK2 prevents human cytomegalovirus replication and virus-induced inflammatory response in infected endothelial cells

Caposio, P., Musso, T., Luganini, A., Inoue, H., Gariglio, M., Landolfo, S. & Gribaudo, G., Mar 1 2007, In : Antiviral Research. 73, 3, p. 175-184 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2006

The expression of p16INK4a tumor suppressor is upregulated by human cytomegalovirus infection and required for optimal viral replication

Zannetti, C., Mondini, M., De Andrea, M., Caposio, P., Hara, E., Peters, G., Gribaudo, G., Gariglio, M. & Landolfo, S., May 25 2006, In : Virology. 349, 1, p. 79-86 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2004

Debridement and local application of tetracycline-loaded fibres in the management of persistent periodontitis: Results after 12 months

Aimetti, M., Romano, F., Torta, I., Cirillo, D., Caposio, P. & Romagnoli, R., Mar 1 2004, In : Journal of Clinical Periodontology. 31, 3, p. 166-172 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Evidence that the Human Cytomegalovirus 46-kDa UL72 protein is not an active dUTPase but a late protein dispensable for replication in fibroblasts

Caposio, P., Riera, L., Hahn, G., Landolfo, S. & Gribaudo, G., Aug 1 2004, In : Virology. 325, 2, p. 264-276 13 p.

Research output: Contribution to journalArticle

23 Scopus citations

Human Cytomegalovirus Stimulates Cellular IKK2 Activity and Requires the Enzyme for Productive Replication

Caposio, P., Dreano, M., Garotta, G., Gribaudo, G. & Landolfo, S., Mar 2004, In : Journal of virology. 78, 6, p. 3190-3195 6 p.

Research output: Contribution to journalArticle

33 Scopus citations
2003

Human cytomegalovirus requires cellular deoxycytidylate deaminase for replication in quiescent cells

Gribaudo, G., Riera, L., Caposio, P., Maley, F. & Landolfo, S., Jun 1 2003, In : Journal of General Virology. 84, 6, p. 1437-1441 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Molecular approaches to the identification and treatment monitoring of periodontal pathogens

Caposio, P., Torta, I., Romano, F., Aimetti, M., Romagnoli, R., Marchiaro, G. & Cirillo, D. M., Jan 1 2003, In : New Microbiologica. 26, 1, p. 121-124 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

The oxygenase component of phenol hydroxylase from Acinetobacter radioresistens S13

Divari, S., Valetti, F., Caposio, P., Pessione, E., Cavaletto, M., Griva, E., Gribaudo, G., Gilardi, G. & Giunta, C., May 1 2003, In : European Journal of Biochemistry. 270, 10, p. 2244-2253 10 p.

Research output: Contribution to journalArticle

32 Scopus citations
2002

Cloning and characterization of two catechol 1,2-dioxygenase genes from Acinetobacter radioresistens S13

Caposio, P., Pessione, E., Giuffrida, G., Conti, A., Landolfo, S., Giunta, C. & Gribaudo, G., Mar 4 2002, In : Research in Microbiology. 153, 2, p. 69-74 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Human cytomegalovirus infection induces cellular thymidylate synthase gene expression in quiescent fibroblasts

Gribaudo, G., Riera, L., Rudge, T. L., Caposio, P., Johnson, L. F. & Landolfo, S., Dec 1 2002, In : Journal of General Virology. 83, 12, p. 2983-2993 11 p.

Research output: Contribution to journalReview article

Open Access
28 Scopus citations
2001

The catechol 1,2 dioxygenase system of Acinetobacter radioresistens: Isoenzymes, inductors and gene localisation

Pessione, E., Giuffrida, M. G., Mazzoli, R., Caposio, P., Landolfo, S., Conti, A., Giunta, C. & Gribaudo, G., Oct 4 2001, In : Biological Chemistry. 382, 8, p. 1253-1261 9 p.

Research output: Contribution to journalArticle

16 Scopus citations