Pamela Hughes

Associate Professor

  • 754 Citations
  • 12 h-Index
19982019
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Research Output 1998 2019

  • 754 Citations
  • 12 h-Index
  • 19 Article
  • 1 Chapter
  • 1 Comment/debate
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Article
2019
1 Citation (Scopus)

From Ripple to Mavericks

Lee, J. S., Bass, B. L., Hughes, P. & Davis-Blake, A., Jan 1 2019, In : Journal of Oral and Maxillofacial Surgery.

Research output: Contribution to journalArticle

How well do we manage the odontogenic keratocyst? A multicenter study

Kinard, B., Hansen, G., Newman, M., Dennis, P., Haeffs, T., Perez, S., Hamao-Sakamoto, A., Steed, M., Hughes, P., August, M. & Abramowicz, S., Apr 1 2019, In : Oral surgery, oral medicine, oral pathology and oral radiology. 127, 4, p. 282-288 7 p.

Research output: Contribution to journalArticle

Odontogenic Cysts
Multicenter Studies
Recurrence
Cystectomy
Decompression
2017
11 Citations (Scopus)

Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons

for UK Primary Sjögren's Syndrome Registry, 2017, In : PLoS Genetics. 13, 6, e1006820.

Research output: Contribution to journalArticle

Interferon Type I
interferons
Ligases
ligases
Protein Isoforms
12 Citations (Scopus)

Rare X Chromosome Abnormalities in Systemic Lupus Erythematosus and Sjögren's Syndrome

Sharma, R., Harris, V. M., Cavett, J., Kurien, B. T., Liu, K., Koelsch, K. A., Fayaaz, A., Chaudhari, K. S., Radfar, L., Lewis, D., Stone, D. U., Kaufman, C. E., Li, S., Segal, B., Wallace, D. J., Weisman, M. H., Venuturupalli, S., Kelly, J. A., Pons-Estel, B., Jonsson, R. & 29 others, Lu, X., Gottenberg, J. E., Anaya, J. M., Cunninghame-Graham, D. S., Huang, A. J. W., Brennan, M. T., Hughes, P., Alevizos, I., Miceli-Richard, C., Keystone, E. C., Bykerk, V. P., Hirschfield, G., Nordmark, G., Bucher, S. M., Eriksson, P., Omdal, R., Rhodus, N. L., Rischmueller, M., Rohrer, M., Wahren-Herlenius, M., Witte, T., Alarcón-Riquelme, M., Mariette, X., Lessard, C. J., Harley, J. B., Ng, W. F., Rasmussen, A., Sivils, K. L. & Scofield, R. H., Nov 1 2017, In : Arthritis and Rheumatology. 69, 11, p. 2187-2192 6 p.

Research output: Contribution to journalArticle

X Chromosome
Chromosome Aberrations
Systemic Lupus Erythematosus
Live Birth
Aneuploidy
2016
23 Citations (Scopus)

Klinefelter's syndrome (47,XXY) is in excess among men with Sjögren's syndrome

Harris, V. M., Sharma, R., Cavett, J., Kurien, B. T., Liu, K., Koelsch, K. A., Rasmussen, A., Radfar, L., Lewis, D., Stone, D. U., Kaufman, C. E., Li, S., Segal, B., Wallace, D. J., Weisman, M. H., Venuturupalli, S., Kelly, J. A., Alarcon-Riquelme, M. E., Pons-Estel, B., Jonsson, R. & 28 others, Lu, X., Gottenberg, J. E., Anaya, J. M., Cunninghame-Graham, D. S., Huang, A. J. W., Brennan, M. T., Hughes, P., Alevizos, I., Miceli-Richard, C., Keystone, E. C., Bykerk, V. P., Hirschfield, G., Xie, G., Ng, W. F., Nordmark, G., Bucher, S. M., Eriksson, P., Omdal, R., Rhodus, N. L., Rischmueller, M., Rohrer, M., Wahren-Herlenius, M., Witte, T., Mariette, X., Lessard, C. J., Harley, J. B., Sivils, K. L. & Scofield, R. H., Jul 1 2016, In : Clinical Immunology. 168, p. 25-29 5 p.

Research output: Contribution to journalArticle

Klinefelter Syndrome
X Chromosome
Systemic Lupus Erythematosus
Y Chromosome
Live Birth
10 Citations (Scopus)

Patients with Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif-Containing Protein 38 Show Greater Disease Severity

Wolska, N., Rybakowska, P., Rasmussen, A., Brown, M., Montgomery, C., Klopocki, A., Grundahl, K., Scofield, R. H., Radfar, L., Stone, D. U., Anaya, J. M., Ice, J. A., Lessard, C. J., Lewis, D. M., Rhodus, N. L., Gopalakrishnan, R., Huang, A. J. W., Hughes, P., Rohrer, M. D., Weisman, M. H. & 6 others, Venuturupalli, S., Guthridge, J. M., James, J. A., Sivils, K. L., Bagavant, H. & Deshmukh, U. S., Mar 1 2016, In : Arthritis and Rheumatology. 68, 3, p. 724-729 6 p.

Research output: Contribution to journalArticle

Autoantibodies
Anti-Idiotypic Antibodies
Cortactin
Serum
Minor Salivary Glands
13 Citations (Scopus)

Serum Markers of Bone Turnover and Angiogenesis in Patients with Bisphosphonate-Related Osteonecrosis of the Jaw after Discontinuation of Long-Term Intravenous Bisphosphonate Therapy

Thumbigere-Math, V., Michalowicz, B. S., Hughes, P., Basi, D. L., Tsai, M. L., Swenson, K. K., Rockwell, L. & Gopalakrishnan, R., Apr 1 2016, In : Journal of Oral and Maxillofacial Surgery. 74, 4, p. 738-746 9 p.

Research output: Contribution to journalArticle

Bisphosphonate-Associated Osteonecrosis of the Jaw
Bone Remodeling
Diphosphonates
Biomarkers
Vascular Endothelial Growth Factor A
43 Citations (Scopus)

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome

Liu, K., Kurien, B. T., Zimmerman, S. L., Kaufman, K. M., Taft, D. H., Kottyan, L. C., Lazaro, S., Weaver, C. A., Ice, J. A., Adler, A. J., Chodosh, J., Radfar, L., Rasmussen, A., Stone, D. U., Lewis, D. M., Li, S., Koelsch, K. A., Igoe, A., Talsania, M., Kumar, J. & 58 others, Maier-Moore, J. S., Harris, V. M., Gopalakrishnan, R., Jonsson, R., Lessard, J. A., Lu, X., Gottenberg, J. E., Anaya, J. M., Cunninghame-Graham, D. S., Huang, A. J. W., Brennan, M. T., Hughes, P., Illei, G. G., Miceli-Richard, C., Keystone, E. C., Bykerk, V. P., Hirschfield, G., Xie, G., Ng, W. F., Nordmark, G., Eriksson, P., Omdal, R., Rhodus, N. L., Rischmueller, M., Rohrer, M., Segal, B. M., Vyse, T. J., Wahren-Herlenius, M., Witte, T., Pons-Estel, B., Alarcón-Riquelme, M. E., Guthridge, J. M., James, J. A., Lessard, C. J., Kelly, J. A., Thompson, S. D., Gaffney, P. M., Montgomery, C. G., Edberg, J. C., Kimberly, R. P., Alarcón, G. S., Langefeld, C. L., Gilkeson, G. S., Kamen, D. L., Tsao, B. P., Joseph McCune, W., Salmon, J. E., Merrill, J. T., Weisman, M. H., Wallace, D. J., Utset, T. O., Bottinger, E. P., Amos, C. I., Siminovitch, K. A., Mariette, X., Sivils, K. L., Harley, J. B. & Hal Scofield, R., May 1 2016, In : Arthritis and Rheumatology. 68, 5, p. 1290-1300 11 p.

Research output: Contribution to journalArticle

Sexism
X Chromosome
Systemic Lupus Erythematosus
Autoimmune Diseases
Biliary Liver Cirrhosis
2015
9 Citations (Scopus)

Salivary proteomics in bisphosphonate-related osteonecrosis of the jaw

Thumbigere-Math, V., Michalowicz, B. S., de Jong, E. P., Griffin, T. J., Basi, D. L., Hughes, P., Tsai, M. L., Swenson, K. K., Rockwell, L. & Gopalakrishnan, R., Jan 1 2015, In : Oral Diseases. 21, 1, p. 46-56 11 p.

Research output: Contribution to journalArticle

Bisphosphonate-Associated Osteonecrosis of the Jaw
Proteomics
Biomarkers
Salivary Proteins and Peptides
Tandem Mass Spectrometry
2014
95 Citations (Scopus)

Comparison of the American-European Consensus Group Sjögren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort

Rasmussen, A., Ice, J. A., Li, H., Grundahl, K., Kelly, J. A., Radfar, L., Stone, D. U., Hefner, K. S., Anaya, J. M., Rohrer, M., Gopalakrishnan, R., Houston, G. D., Lewis, D. M., Chodosh, J., Harley, J. B., Hughes, P., Maier-Moore, J. S., Montgomery, C. G., Rhodus, N. L., Farris, A. D. & 5 others, Segal, B. M., Jonsson, R., Lessard, C. J., Scofield, R. H. & Moser Sivils, K. L., Jan 2014, In : Annals of the Rheumatic Diseases. 73, 1, p. 31-38 8 p.

Research output: Contribution to journalArticle

Rheumatology
Gene expression
Transcriptome
Minor Salivary Glands
Lacrimal Apparatus
2013
218 Citations (Scopus)

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome

Lessard, C. J., Li, H., Adrianto, I., Ice, J. A., Rasmussen, A., Grundahl, K. M., Kelly, J. A., Dozmorov, M. G., Miceli-Richard, C., Bowman, S., Lester, S., Eriksson, P., Eloranta, M. L., Brun, J. G., Gøransson, L. G., Harboe, E., Guthridge, J. M., Kaufman, K. M., Kvarnström, M., Jazebi, H. & 40 others, Graham, D. S. C., Grandits, M. E., Nazmul-Hossain, A. N. M., Patel, K., Adler, A. J., Maier-Moore, J. S., Farris, A. D., Brennan, M. T., Lessard, J. A., Chodosh, J., Gopalakrishnan, R., Hefner, K. S., Houston, G. D., Huang, A. J. W., Hughes, P., Lewis, D. M., Radfar, L., Rohrer, M. D., Stone, D. U., Wren, J. D., Vyse, T. J., Gaffney, P. M., James, J. A., Omdal, R., Wahren-Herlenius, M., Illei, G. G., Witte, T., Jonsson, R., Rischmueller, M., Rönnblom, L., Nordmark, G., Ng, W. F., Mariette, X., Anaya, J. M., Rhodus, N. L., Segal, B. M., Scofield, R. H., Montgomery, C. G., Harley, J. B. & Sivils, K. L., Nov 2013, In : Nature Genetics. 45, 11, p. 1284-1294 11 p.

Research output: Contribution to journalArticle

Adaptive Immunity
Innate Immunity
Keratoconjunctivitis Sicca
Xerostomia
HLA Antigens
2012
44 Citations (Scopus)

A retrospective study evaluating frequency and risk factors of osteonecrosis of the jaw in 576 cancer patients receiving intravenous bisphosphonates

Thumbigere-Math, V., Tu, L., Huckabay, S., Dudek, A. Z., Lunos, S., Basi, D. L., Hughes, P., Leach, J. W., Swenson, K. K. & Gopalakrishnan, R., Aug 2012, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 35, 4, p. 386-392 7 p.

Research output: Contribution to journalArticle

Osteonecrosis
Diphosphonates
Jaw
Retrospective Studies
Neoplasms
22 Citations (Scopus)

Human temporomandibular joint and myofascial pain biochemical profiles: A case-control study

Basi, D. L., Velly, A. M., Schiffman, E. L., Lenton, P. A., Besspiata, D. A., Rankin, A. M., Hughes, P., Swift, J. Q. & Kehl, L. J., May 2012, In : Journal of Oral Rehabilitation. 39, 5, p. 326-337 12 p.

Research output: Contribution to journalArticle

Temporomandibular Joint
Arthralgia
Case-Control Studies
Masseter Muscle
Temporomandibular Joint Disorders
2011
9 Citations (Scopus)

Genetics and genomics of Sjgren's syndrome: Research provides clues to pathogenesis and novel therapies

Segal, B. M., Nazmul-Hossain, A. N. M., Patel, K., Hughes, P., Moser, K. L. & Rhodus, N. L., Jun 2011, In : Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology and Endodontology. 111, 6, p. 673-680 8 p.

Research output: Contribution to journalArticle

Genomics
Research
Genes
Technology
B-Lymphocytes
21 Citations (Scopus)

Matrix metalloproteinase-9 expression in alveolar extraction sockets of zoledronic acid-treated rats

Basi, D. L., Hughes, P., Thumbigere-Math, V., Sabino, MA., Mariash, A., Lunos, S. A., Jensen, E. & Gopalakrishnan, R., Nov 2011, In : Journal of Oral and Maxillofacial Surgery. 69, 11, p. 2698-2707 10 p.

Research output: Contribution to journalArticle

zoledronic acid
Matrix Metalloproteinase 9
Tooth Extraction
Diphosphonates
Wound Healing
2009
1 Citation (Scopus)

Academic integrity in dental school: a call to action.

Hughes, P., Bean, C. Y., Duff, R. E., Duncan, J. P., Feldman, C. A., Guarente, J. F., Marucha, P. & Pousson, R. L., Jun 2009, In : The Journal of the American College of Dentists. 76, 2, p. 31-37 7 p.

Research output: Contribution to journalArticle

Dental Schools
Dentistry
Dental Education
Students
Education
59 Citations (Scopus)

Bisphosphonate-Related Osteonecrosis of the Jaw: Clinical Features, Risk Factors, Management, and Treatment Outcomes of 26 Patients

Thumbigere-Math, V., Sabino, MA. C., Gopalakrishnan, R., Huckabay, S., Dudek, A. Z., Basu, S., Hughes, P., Michalowicz, B. S., Leach, J. W., Swenson, K. K., Swift, J. Q., Adkinson, C. & Basi, D. L., Sep 2009, In : Journal of Oral and Maxillofacial Surgery. 67, 9, p. 1904-1913 10 p.

Research output: Contribution to journalArticle

Bisphosphonate-Associated Osteonecrosis of the Jaw
Osteonecrosis
Risk Management
Jaw
Diphosphonates
2008
96 Citations (Scopus)

Prevalence, severity, and predictors of fatigue in subjects with primary Sjögren's syndrome

Segal, B., Thomas, W., Rogers, T., Leon, J. M., Hughes, P., Patel, D., Patel, K., Novitzke, J., Rohrer, M., Gopalakrishnan, R., Myers, S., Nazmul-Hossain, A., Emamian, E., Huang, A., Rhodus, N. & Moser, K., Dec 15 2008, In : Arthritis Care and Research. 59, 12, p. 1780-1787 8 p.

Research output: Contribution to journalArticle

Fatigue
Mental Fatigue
Depression
Visual Analog Scale
1998
67 Citations (Scopus)

The effect of three finishing systems on four esthetic restorative materials

Hoelscher, D. C., Neme, A. M. L., Pink, F. E. & Hughes, P., Jan 1998, In : Operative Dentistry. 23, 1, p. 36-42 7 p.

Research output: Contribution to journalArticle

Esthetics
Aluminum Oxide
Bisphenol A-Glycidyl Methacrylate
Materials Testing
Glass Ionomer Cements