Motomi (Tomi) Mori

Professor

  • 10261 Citations
  • 54 h-Index
1988 …2020

Research output per year

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Research Output

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Article
2020

Simultaneous kinase inhibition with ibrutinib and BCL2 inhibition with venetoclax offers a therapeutic strategy for acute myeloid leukemia

Eide, C. A., Kurtz, S. E., Kaempf, A., Long, N., Agarwal, A., Tognon, C. E., Mori, M., Druker, B. J., Chang, B. H., Danilov, A. V. & Tyner, J. W., Jan 1 2020, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial

Zhang, Z., Garzotto, M., Davis, E. W., Mori, M., Stoller, W. A., Farris, P. E., Wong, C. P., Beaver, L. M., Thomas, G. V., Williams, D. E., Dashwood, R. H., Hendrix, D. A., Ho, E. & Shannon, J., Jan 2 2020, In : Nutrition and Cancer. 72, 1, p. 74-87 14 p.

Research output: Contribution to journalArticle

2019

Association Between Postpartum Breast Cancer Diagnosis and Metastasis and the Clinical Features Underlying Risk

Goddard, E. T., Bassale, S., Schedin, T., Jindal, S., Johnston, J., Cabral, E., Latour, E., Lyons, T. R., Mori, M., Schedin, P. J. & Borges, V. F., Jan 4 2019, In : JAMA Network Open. 2, 1, p. e186997

Research output: Contribution to journalArticle

Open Access

CSF1R inhibitors exhibit antitumor activity in acute myeloid leukemia by blocking paracrine signals from support cells

Edwards, D. K., Watanabe-Smith, K., Rofelty, A., Damnernsawad, A., Laderas, T., Lamble, A., Lind, E. F., Kaempf, A., Mori, M., Rosenberg, M., d’Almeida, A., Long, N., Agarwal, A., Sweeney, D. T., Loriaux, M., McWeeney, S. K. & Tyner, J. W., Feb 7 2019, In : Blood. 133, 6, p. 588-599 12 p.

Research output: Contribution to journalArticle

8 Scopus citations

Phase 1–2 study of vorinostat (SAHA), cladribine and rituximab (SCR) in relapsed B-cell non-Hodgkin lymphoma and previously untreated mantle cell lymphoma

Spurgeon, S., Sharma, K., Claxton, D. F., Ehmann, C., Pu, J., Shimko, S., Stewart, A., Subbiah, N., Palmbach, G., LeBlanc, F., Latour, E., Chen, Y., Mori, M. T., Hasanali, Z. & Epner, E. M., Jan 1 2019, In : British Journal of Haematology.

Research output: Contribution to journalArticle

2 Scopus citations
2018

A Phase II Study of Celecoxib with Irinotecan, 5-Fluorouracil, and Leucovorin in Patients with Previously Untreated Advanced or Metastatic Colorectal Cancer

Chen, E. Y., Blanke, C., Haller, D. G., Benson, A. B., Dragovich, T., Lenz, H. J., Robles, C., Li, H., Mori, M. T., Mattek, N., Sanborn, R. E. & Lopez, C., Dec 1 2018, In : American Journal of Clinical Oncology: Cancer Clinical Trials. 41, 12, p. 1193-1198 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Dual inhibition of JAK1/2 kinases and BCL2: a promising therapeutic strategy for acute myeloid leukemia

Kurtz, S. E., Eide, C. A., Kaempf, A., Mori, M., Tognon, C. E., Borate, U., Druker, B. J. & Tyner, J. W., Sep 1 2018, In : Leukemia. 32, 9, p. 2025-2028 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Functional genomic landscape of acute myeloid leukaemia

Tyner, J. W., Tognon, C. E., Bottomly, D., Wilmot, B., Kurtz, S. E., Savage, S. L., Long, N., Schultz, A. R., Traer, E., Abel, M., Agarwal, A., Blucher, A., Borate, U., Bryant, J., Burke, R., Carlos, A., Carpenter, R., Carroll, J., Chang, B. H., Coblentz, C. & 68 others, d’Almeida, A., Cook, R., Danilov, A., Dao, K. H. T., Degnin, M., Devine, D., Dibb, J., Edwards, D. K., Eide, C. A., English, I., Glover, J., Henson, R., Ho, H., Jemal, A., Johnson, K., Johnson, R., Junio, B., Kaempf, A., Leonard, J., Lin, C., Liu, S. Q., Lo, P., Loriaux, M. M., Luty, S., Macey, T., MacManiman, J., Martinez, J., Mori, M., Nelson, D., Nichols, C., Peters, J., Ramsdill, J., Rofelty, A., Schuff, R., Searles, R., Segerdell, E., Smith, R. L., Spurgeon, S. E., Sweeney, T., Thapa, A., Visser, C., Wagner, J., Watanabe-Smith, K., Werth, K., Wolf, J., White, L., Yates, A., Zhang, H., Cogle, C. R., Collins, R. H., Connolly, D. C., Deininger, M. W., Drusbosky, L., Hourigan, C. S., Jordan, C. T., Kropf, P., Lin, T. L., Martinez, M. E., Medeiros, B. C., Pallapati, R. R., Pollyea, D. A., Swords, R. T., Watts, J. M., Weir, S. J., Wiest, D. L., Winters, R. M., McWeeney, S. K. & Druker, B. J., Oct 25 2018, In : Nature. 562, 7728, p. 526-531 6 p.

Research output: Contribution to journalArticle

90 Scopus citations

IFNγ-activated dermal lymphatic vessels inhibit cytotoxic T cells in melanoma and inflamed skin

Lane, R. S., Femel, J., Breazeale, A. P., Loo, C. P., Thibault, G., Kaempf, A., Mori, M., Tsujikawa, T., Chang, Y. H. & Lund, A. W., Dec 1 2018, In : Journal of Experimental Medicine. 215, 12, p. 3057-3074 18 p.

Research output: Contribution to journalArticle

17 Scopus citations

Inhibition of interleukin-1 receptor-associated kinase-1 is a therapeutic strategy for acute myeloid leukemia subtypes

Hosseini, M. M., Kurtz, S. E., Abdelhamed, S., Mahmood, S., Davare, M. A., Kaempf, A., Elferich, J., McDermott, J. E., Liu, T., Payne, S. H., Shinde, U., Rodland, K. D., Mori, M., Druker, B. J., Singer, J. W. & Agarwal, A., Nov 1 2018, In : Leukemia. 32, 11, p. 2374-2387 14 p.

Research output: Contribution to journalArticle

7 Scopus citations

MiR-486-5p Downregulation Marks an Early Event in Colorectal Carcinogenesis

Kelley, K. A., Wieghard, N., Chin, Y., Potter, A., Mori, M. T., Wong, M., Chin, K-Y. & Tsikitis, V., Nov 1 2018, In : Diseases of the Colon and Rectum. 61, 11, p. 1290-1296 7 p.

Research output: Contribution to journalArticle

4 Scopus citations

Perceptions of control and unrealistic optimism in early-phase cancer trials

Jansen, L., Mahadevan, D., Appelbaum, P. S., Klein, W. M. P., Weinstein, N. D., Mori, M. T., Degnin, C. & Sulmasy, D. P., Feb 1 2018, In : Journal of Medical Ethics. 44, 2, p. 121-127 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

Assessing Community Cancer care after insurance ExpanSionS (ACCESS) study protocol

Angier, H., Huguet, N., Marino, M., Mori, M. T., Winters-Stone, K., Shannon, J. J., Raynor, L., Holderness, H. & Devoe, J., Sep 1 2017, In : Contemporary Clinical Trials Communications. 7, p. 136-140 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Comprehensive definition of human immunodominant CD8 antigens in tuberculosis

Lewinsohn, D., Swarbrick, G. M., Park, B., Cansler, M. E., Null, M. D., Toren, K. G., Baseke, J., Zalwango, S., Mayanja-Kizza, H., Malone, L. L., Nyendak, M., Wu, G., Guinn, K., McWeeney, S., Mori, M. T., Chervenak, K. A., Sherman, D. R., Boom, W. H. & Lewinsohn, D., Dec 1 2017, In : npj Vaccines. 2, 1, 8.

Research output: Contribution to journalArticle

14 Scopus citations

Molecularly targeted drug combinations demonstrate selective effectiveness for myeloid- and lymphoid-derived hematologic malignancies

Kurtz, S. E., Eide, C. A., Kaempf, A., Khanna, V., Savage, S. L., Rofelty, A., English, I., Ho, H., Pandya, R., Bolosky, W. J., Poon, H., Deininger, M. W., Collins, R., Swords, R. T., Watts, J., Pollyea, D. A., Medeiros, B. C., Traer, E., Tognon, C. E., Mori, M. & 2 others, Druker, B. J. & Tyner, J. W., Sep 5 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 36, p. E7554-E7563

Research output: Contribution to journalArticle

34 Scopus citations

Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis

Tsujikawa, T., Kumar, S., Borkar, R. N., Azimi, V., Thibault, G., Chang, Y. H., Balter, A., Kawashima, R., Choe, G., Sauer, D., El Rassi, E., Clayburgh, D., Kulesz-Martin, M., Lutz, E. R., Zheng, L., Jaffee, E. M., Leyshock, P., Margolin, A., Mori, M. T., Gray, J. & 2 others, Flint, P. & Coussens, L., Apr 4 2017, In : Cell Reports. 19, 1, p. 203-217 15 p.

Research output: Contribution to journalArticle

113 Scopus citations
6 Scopus citations

The rodent liver undergoes weaning-induced involution and supports breast cancer metastasis

Goddard, E. T., Hill, R. C., Nemkov, T., D’Alessandro, A., Hansen, K. C., Maller, O., Mongoue-Tchokote, S., Mori, M. T., Partridge, A. H., Borges, V. F. & Schedin, P., Feb 1 2017, In : Cancer Discovery. 7, 2, p. 177-187 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Variations in Unrealistic Optimism between Acceptors and Decliners of Early Phase Cancer Trials

Jansen, L., Mahadevan, D., Appelbaum, P. S., Klein, W. M. P., Weinstein, N. D., Mori, M. T., Degnin, C. & Sulmasy, D. P., Oct 1 2017, In : Journal of Empirical Research on Human Research Ethics. 12, 4, p. 280-288 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2016

A new statistical decision rule for single-arm phase II oncology trials

Chen, Y., Chen, Z. & Mori, M. T., Feb 1 2016, In : Statistical Methods in Medical Research. 25, 1, p. 118-132 15 p.

Research output: Contribution to journalArticle

3 Scopus citations

Clonal hematopoiesis as determined by the HUMARA assay is a marker for acquired mutations in epigenetic regulators in older women

Wiedmeier, J. E., Kato, C., Zhang, Z., Lee, H., Dunlap, J., Nutt, E., Rattray, R., McKay, S., Eide, C., Press, R., Mori, M. T., Druker, B. & Dao, K-H., Sep 1 2016, In : Experimental Hematology. 44, 9, p. 857-865.e5

Research output: Contribution to journalArticle

2 Scopus citations

Dispositional optimism and therapeutic expectations in early-phase oncology trials

Jansen, L., Mahadevan, D., Appelbaum, P. S., Klein, W. M. P., Weinstein, N. D., Mori, M. T., Daffé, R. & Sulmasy, D. P., 2016, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

17 Scopus citations

Durability of Vaccine-Induced Immunity Against Tetanus and Diphtheria Toxins: A Cross-sectional Analysis

Hammarlund, E., Thomas, A., Poore, E. A., Amanna, I. J., Rynko, A. E., Mori, M. T., Chen, Z. & Slifka, M., May 1 2016, In : Clinical Infectious Diseases. 62, 9, p. 1111-1118 8 p.

Research output: Contribution to journalArticle

17 Scopus citations

Effects of ω-3 Fatty Acids and Catechins on Fatty Acid Synthase in the Prostate: A Randomized Controlled Trial

Zhang, Z., Garzotto, M., Beer, T. M., Thuillier, P., Lieberman, S., Mori, M., Stoller, W. A., Farris, P. E. & Shannon, J., Nov 16 2016, In : Nutrition and Cancer. 68, 8, p. 1309-1319 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

MicroRNA signatures of colonic polyps on screening and histology

Tsikitis, V., Potter, A., Mori, M. T., Buckmeier, J. A., Preece, C. R., Harrington, C. C., Bartley, A. N., Bhattacharyya, A. K., Hamilton, S. R., Lance, M. P. & Thompson, P. A., Dec 1 2016, In : Cancer Prevention Research. 9, 12, p. 942-949 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

The Impact of unreaslistic optimism on informed consent in early-phase oncology trials

Jansen, L., Mahadevan, D., Appelbaum, P. S., Klein, W. M. P., Weinstein, N. D., Mori, M. T., Daffe, R. & Sulmasy, D. P., Sep 1 2016, In : IRB Ethics and Human Research. 38, 5, p. 1-7 7 p.

Research output: Contribution to journalArticle

6 Scopus citations

Treatment and Survival of Small-bowel Adenocarcinoma in the United States: A Comparison with Colon Cancer

Young, J. I., Mongoue-Tchokote, S., Wieghard, N., Mori, M. T., Vaccaro, G., Sheppard, B. & Tsikitis, V., Apr 1 2016, In : Diseases of the Colon and Rectum. 59, 4, p. 306-315 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
2015

A phase II study of sulforaphane-rich broccoli sprout extracts in men with recurrent prostate cancer

Alumkal, J. J., Slottke, R., Schwartzman, J., Cherala, G., Munar, M., Graff, J. N., Beer, T. M., Ryan, C. W., Koop, D. R., Gibbs, A., Gao, L., Flamiatos, J. F., Tucker, E., Kleinschmidt, R. & Mori, M., Apr 1 2015, In : Investigational New Drugs. 33, 2, p. 480-489 10 p.

Research output: Contribution to journalArticle

79 Scopus citations

Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes

Huan, J., Hornick, N. I., Goloviznina, N. A., Kamimae-Lanning, A. N., David, L., Wilmarth, P., Mori, M. T., Chevillet, J. R., Narla, A., Roberts, C., Loriaux, M., Chang, B. & Kurre, P., Jun 25 2015, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

40 Scopus citations

Sulforaphane bioavailability and chemopreventive activity in women scheduled for breast biopsy

Atwell, L. L., Zhang, Z., Mori, M. T., Farris, P. E., Vetto, J., Naik, A., Oh, K., Thuillier, P., Ho, E. & Shannon, J. J., Dec 1 2015, In : Cancer Prevention Research. 8, 12, p. 1184-1191 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2014

Assisted movement with proprioceptive stimulation reduces impairment and restores function in incomplete spinal cord injury

Backus, D., Cordo, P., Gillott, A., Kandilakis, C., Mori, M. & Raslan, A. M., Aug 2014, In : Archives of Physical Medicine and Rehabilitation. 95, 8, p. 1447-1453 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Differences in knowledge, attitudes, beliefs, and perceived risks regarding colorectal cancer screening among Chinese, Korean, and Vietnamese sub-groups

Le, T. D., Carney, P. A., Lee-Lin, F., Mori, M., Chen, Z., Leung, H., Lau, C. & Lieberman, D. A., Apr 2014, In : Journal of Community Health. 39, 2, p. 248-265 18 p.

Research output: Contribution to journalArticle

14 Scopus citations

Differential expression of microRNA-320a, -145, and -192 along the continuum of normal mucosa to high-grade dysplastic adenomas of the colorectum

Tsikitis, V. L., White, I., Mori, M., Potter, A., Bhattcharyya, A., Hamilton, S. R., Buckmeier, J., Lance, P. & Thompson, P., May 2014, In : American journal of surgery. 207, 5, p. 717-722 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Improving colorectal cancer screening in Asian Americans: Results of a randomized intervention study

Carney, P. A., Lee-Lin, F., Mongoue-Tchokote, S., Mori, M., Leung, H., Lau, C., Le, T. D. & Lieberman, D. A., Jun 1 2014, In : Cancer. 120, 11, p. 1702-1712 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Reducing misclassification bias in cervical dysplasia risk factor analysis with p16-based diagnoses

Meserve, E., Berlin, M., Mori, T., Krum, R. & Morgan, T. K., Jul 2014, In : Journal of lower genital tract disease. 18, 3, p. 266-272 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
25 Scopus citations
2013

Agent Orange as a risk factor for high-grade prostate cancer

Ansbaugh, N., Shannon, J., Mori, M., Farris, P. E. & Garzotto, M., Jul 1 2013, In : Cancer. 119, 13, p. 2399-2404 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Association between documented family history of cancer and screening for breast and colorectal cancer

Carney, P. A., O'Malley, J. P., Gough, A., Buckley, D. I., Wallace, J., Fagnan, L. J., Morris, C., Mori, M., Heintzman, J. D. & Lieberman, D., Nov 1 2013, In : Preventive medicine. 57, 5, p. 679-684 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Comparison of antibiograms developed for inpatients and primary care outpatients

McGregor, J. C., Bearden, D. T., Townes, J. M., Sharp, S. E., Gorman, P. N., Elman, M. R., Mori, M. & Smith, D. H., May 1 2013, In : Diagnostic Microbiology and Infectious Disease. 76, 1, p. 73-79 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Documentation and management of CKD in rural primary care

Rao, M. K., Morris, C. D., O'Malley, J. P., Davis, M. M., Mori, M. & Anderson, S., May 7 2013, In : Clinical Journal of the American Society of Nephrology. 8, 5, p. 739-748 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Fusion between Hematopoietic and Epithelial Cells in Adult Human Intestine

Silk, A. D., Gast, C. E., Davies, P. S., Fakhari, F. D., Vanderbeek, G. E., Mori, M. & Wong, M. H., Jan 30 2013, In : PloS one. 8, 1, e55572.

Research output: Contribution to journalArticle

15 Scopus citations

Patient activation and improved outcomes in HIV-infected patients

Marshall, R., Beach, M. C., Saha, S., Mori, T., Loveless, M. O., Hibbard, J. H., Cohn, J. A., Sharp, V. L. & Korthuis, P. T., May 1 2013, In : Journal of general internal medicine. 28, 5, p. 668-674 7 p.

Research output: Contribution to journalArticle

55 Scopus citations

Phase i trial of preoperative chemoradiation plus sorafenib for high-risk extremity soft tissue sarcomas with dynamic contrast-enhanced MRI correlates

Meyer, J. M., Perlewitz, K. S., Hayden, J. B., Doung, Y. C., Hung, A. Y., Vetto, J. T., Pommier, R. F., Mansoor, A., Beckett, B. R., Tudorica, A., Mori, M., Holtorf, M. L., Afzal, A., Woodward, W. J., Rodler, E. T., Jones, R. L., Huang, W. & Ryan, C. W., Dec 15 2013, In : Clinical Cancer Research. 19, 24, p. 6902-6911 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Provider practice characteristics that promote interpersonal continuity

Mittelstaedt, T. S., Mori, M., Lambert, W. E. & Saultz, J. W., Jul 1 2013, In : Journal of the American Board of Family Medicine. 26, 4, p. 356-365 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
2012

CD8 + T cells provide an immunologic signature of tuberculosis in young children

Lancioni, C., Nyendak, M., Kiguli, S., Zalwango, S., Mori, T., Mayanja-Kizza, H., Balyejusa, S., Null, M., Baseke, J., Mulindwa, D., Byrd, L., Swarbrick, G., Scott, C., Johnson, D. F., Malone, L. S., Mudido-Musoke, P., Boom, W. H., Lewinsohn, D. M. & Lewinsohn, D. A., Jan 15 2012, In : American journal of respiratory and critical care medicine. 185, 2, p. 206-212 7 p.

Research output: Contribution to journalArticle

38 Scopus citations
2011

A DNA methylation microarray-based study identifies ERG as a gene commonly methylated in prostate cancer

Schwartzman, J., Mongoue-Tchokote, S., Gibbs, A., Gao, L., Corless, C. L., Jin, J., Zarour, L., Higano, C., True, L. D., Vessella, R. L., Wilmot, B., Bottomly, D., McWeeney, S. K., Bova, S. G., Partin, A. W., Mori, M. & Alumkal, J. J., Oct 2011, In : Epigenetics. 6, 10, p. 1248-1256 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

Sequential immunization with a subtype B HIV-1 envelope quasispecies partially mimics the in Vivo development of neutralizing antibodies

Malherbe, D. C., Doria-Rose, N. A., Misher, L., Beckett, T., Puryear, W. B., Schuman, J. T., Kraft, Z., O'Malley, J., Mori, M., Srivastava, I., Barnett, S., Stamatatos, L. & Haigwood, N. L., Jun 1 2011, In : Journal of virology. 85, 11, p. 5262-5274 13 p.

Research output: Contribution to journalArticle

61 Scopus citations
2010

Adjuvant therapy and survival after resection of pancreatic adenocarcinoma: A population-based analysis

Mayo, S. C., Austin, D. F., Sheppard, B. C., Mori, M., Shipley, D. K. & Billingsley, K. G., Jun 15 2010, In : Cancer. 116, 12, p. 2932-2940 9 p.

Research output: Contribution to journalArticle

19 Scopus citations

Antiviral immunity following smallpox virus infection: A case-control study

Hammarlund, E., Lewis, M. W., Hanifin, J. M., Mori, M., Koudelka, C. W. & Slifka, M. K., Dec 1 2010, In : Journal of virology. 84, 24, p. 12754-12760 7 p.

Research output: Contribution to journalArticle

30 Scopus citations

Erythrocyte fatty acids and prostate cancer risk: A comparison of methods

Shannon, J., O'Malley, J., Mori, M., Garzotto, M., Palma, A. J. & King, I. B., Sep 1 2010, In : Prostaglandins Leukotrienes and Essential Fatty Acids. 83, 3, p. 161-169 9 p.

Research output: Contribution to journalArticle

19 Scopus citations