Michael Klein

Professor

  • Source: Scopus
  • Calculated based on no. of publications stored in Pure and citations from Scopus
1974 …2020

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  • 2020

    A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration

    International AMD Genomics Consortium (IAMDGC), Dec 1 2020, In: Scientific Reports. 10, 1, 1584.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    6 Scopus citations
  • Incidence of Macular Atrophy after Untreated Neovascular Age-Related Macular Degeneration: Age-Related Eye Disease Study Report 40

    Christakis, P. G., Agrón, E., Klein, M. L., Clemons, T. E., Campbell, J. P., Ferris, F. L., Chew, E. Y. & Keenan, T. D., Jun 2020, In: Ophthalmology. 127, 6, p. 784-792 9 p.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • 2019

    Assessment of Novel Genome-Wide Significant Gene Loci and Lesion Growth in Geographic Atrophy Secondary to Age-Related Macular Degeneration

    Grassmann, F., Harsch, S., Brandl, C., Kiel, C., Nürnberg, P., Toliat, M. R., Fleckenstein, M., Pfau, M., Schmitz-Valckenberg, S., Holz, F. G., Chew, E. Y., Swaroop, A., Ratnapriya, R., Klein, M. L., Mulyukov, Z., Zamiri, P. & Weber, B. H. F., Aug 2019, In: JAMA ophthalmology. 137, 8, p. 867-876 10 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17

    Age-Related Eye Disease Study 2 Research Group, Feb 2019, In: Ophthalmology. 126, 2, p. 261-273 13 p.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • 4 Scopus citations
  • Precursors and Development of Geographic Atrophy with Autofluorescence Imaging: Age-Related Eye Disease Study 2 Report Number 18

    Age-Related Eye Disease Study 2 Research Group, Sep 2019, In: Ophthalmology Retina. 3, 9, p. 724-733 10 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • 2018

    Genome-wide analysis of disease progression in age-related macular degeneration

    AREDS2 Research Group, Mar 1 2018, In: Human molecular genetics. 27, 5, p. 929-940 12 p.

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations
  • Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16

    AREDS2 Research Group, Dec 2018, In: Ophthalmology. 125, 12, p. 1913-1928 16 p.

    Research output: Contribution to journalArticlepeer-review

    44 Scopus citations
  • 2017

    Bivariate analysis of age-related macular degeneration progression using genetic risk scores

    Ding, Y., Liu, Y., Yan, Q., Fritsche, L. G., Cook, R. J., Clemons, T., Ratnapriya, R., Klein, M. L., Abecasis, G. R., Swaroop, A., Chew, E. Y., Weeks, D. E. & Chen, W., May 2017, In: Genetics. 206, 1, p. 119-133 15 p.

    Research output: Contribution to journalArticlepeer-review

    23 Scopus citations
  • CLINICOPATHOLOGIC CORRELATION of RETINAL ANGIOMATOUS PROLIFERATION TREATED with RANIBIZUMAB

    Skalet, A. H., Miller, A. K., Klein, M. L., Lauer, A. K. & Wilson, D. J., Aug 1 2017, In: Retina. 37, 8, p. 1620-1624 5 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

    International AMD Genomics Consortium (IAMDGC), Mar 27 2017, In: Genome Medicine. 9, 1, 29.

    Research output: Contribution to journalArticlepeer-review

    35 Scopus citations
  • Recombinant haplotypes narrow the ARMS2/HTRA1 association signal for age-related macular degeneration

    International AMD Genomics Consortium (IAMDGC), Feb 2017, In: Genetics. 205, 2, p. 919-924 6 p.

    Research output: Contribution to journalArticlepeer-review

    31 Scopus citations
  • 2016

    A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

    Fritsche, L. G., Igl, W., Bailey, J. N. C., Grassmann, F., Sengupta, S., Bragg-Gresham, J. L., Burdon, K. P., Hebbring, S. J., Wen, C., Gorski, M., Kim, I. K., Cho, D., Zack, D., Souied, E., Scholl, H. P. N., Bala, E., ELee, K., Hunter, D. J., Sardell, R. J., Mitchell, P. & 142 others, Merriam, J. E., Cipriani, V., Hoffman, J. D., Schick, T., Lechanteur, Y. T. E., Guymer, R. H., Johnson, M. P., Jiang, Y., Stanton, C. M., Buitendijk, G. H. S., Zhan, X., Kwong, A. M., Boleda, A., Brooks, M., Gieser, L., Ratnapriya, R., Branham, K. E., Foerster, J. R., Heckenlively, J. R., Othman, M. I., Vote, B. J., Liang, H. H., Souzeau, E., McAllister, I. L., Isaacs, T., Hall, J., Lake, S., Mackey, D. A., Constable, I. J., Craig, J. E., Kitchner, T. E., Yang, Z., Su, Z., Luo, H., Chen, D., Ouyang, H., Flagg, K., Lin, D., Mao, G., Ferreyra, H., Stark, K., Von Strachwitz, C. N., Wolf, A., Brandl, C., Rudolph, G., Olden, M., Morrison, M. A., Morgan, D. J., Schu, M., Ahn, J., Silvestri, G., Tsironi, E. E., Park, K. H., Farrer, L. A., Orlin, A., Brucker, A., Li, M., Curcio, C. A., Mohand-Sa'd, S., Sahel, J. A., Audo, I., Benchaboune, M., Cree, A. J., Rennie, C. A., Goverdhan, S. V., Grunin, M., Hagbi-Levi, S., Campochiaro, P., Katsanis, N., Holz, F. G., Blond, F., Blanché, H., Deleuze, J. F. O., Igo, R. P., Truitt, B., Peachey, N. S., Meuer, S. M., Myers, C. E., Moore, E. L., Klein, R., Hauser, M. A., Postel, E. A., Courtenay, M. D., Schwartz, S. G., Kovach, J. L., Scott, W. K., Liew, G., Tan, A. G., Gopinath, B., Merriam, J. C., Smith, R. T., Khan, J. C., Shahid, H., Moore, A. T., McGrath, J. A., Laux, R., Brantley, M. A., Agarwal, A., Ersoy, L., Caramoy, A., Langmann, T., Saksens, N. T. M., Jong, E. K., Hoyng, C. B., Cain, M. S., Richardson, A. J., Martin, T. M., Blangero, J., Weeks, D. E., Dhillon, B., Van Duijn, C. M., Doheny, K. F., Romm, J., Klaver, C. C. W., Hayward, C., Gorin, M. B., Klein, M. L., Baird, P. N., Den Hollander, A. I., Fauser, S., WYates, J. R., Allikmets, R., Wang, J. J., Schaumberg, D. A., Klein, B. E. K., Hagstrom, S. A., Chowers, I., Lotery, A. J., Léveillard, T., Zhang, K., Brilliant, M. H., Hewitt, A. W., Swaroop, A., Chew, E. Y., Pericak-Vance, M. A., DeAngelis, M., Stambolian, D., Haines, J. L., Iyengar, S. K., Weber, B. H. F., Abecasis, G. R. & Heid, I. M., Feb 1 2016, In: Nature genetics. 48, 2, p. 134-143 10 p.

    Research output: Contribution to journalArticlepeer-review

    529 Scopus citations
  • 2015

    Clinical and genetic factors associated with progression of geographic atrophy lesions in age-related macular degeneration

    Grassmann, F., Fleckenstein, M., Chew, E. Y., Strunz, T., Schmitz-Valckenberg, S., Göbel, A. P., Klein, M. L., Ratnapriya, R., Swaroop, A., Holz, F. G. & Weber, B. H. F., May 11 2015, In: PloS one. 10, 5, e0126636.

    Research output: Contribution to journalArticlepeer-review

    41 Scopus citations
  • Genetic testing in persons with age-related macular degeneration and the use of the AREDS supplements: To test or not to test?

    Chew, E. Y., Klein, M. L., Clemons, T. E., Agrón, E. & Abecasis, G. R., Jan 1 2015, In: Ophthalmology. 122, 1, p. 212-215 4 p.

    Research output: Contribution to journalArticlepeer-review

    37 Scopus citations
  • Joint Associations of Diet, Lifestyle, and Genes with Age-Related Macular Degeneration

    Meyers, K. J., Liu, Z., Millen, A. E., Iyengar, S. K., Blodi, B. A., Johnson, E., Snodderly, D. M., Klein, M. L., Gehrs, K. M., Tinker, L., Sarto, G. E., Robinson, J., Wallace, R. B. & Mares, J. A., Nov 2015, In: Ophthalmology. 122, 11, p. 2286-2294 9 p.

    Research output: Contribution to journalArticlepeer-review

    34 Scopus citations
  • Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials

    Willoughby, A. S., Ying, G. S., Toth, C. A., Maguire, M. G., Burns, R. E., Grunwald, J. E., Daniel, E., Jaffe, G. J., Williams, D. F., Beardsley, S., Bennett, S., Cantrill, H., Chan-Tram, C., Cheshier, H., Damato, K., Davies, J., Dev, S., Enloe, J., Follano, G., Gilbert, P. & 842 others, Johnson, J., Jones, T., Mayleben, L., Mittra, R., Moos, M., Neist, R., Oestreich, N., Quiram, P., Ramsay, R., Ryan, E., Schindeldecker, S., Snater, J., Steele, T., Selders, D., Tonsfeldt, J., Valardi, S., Fish, G. E., Aguado, H. A., Arceneaux, S., Arnwine, J., Bell, K., Bell, T., Boleman, B., Bradley, P., Callanan, D., Coors, L., Creighton, J., Crew, T., Cummings, K., Dock, C., Duignan, K., Fuller, D., Gray, K., Hendrix, B., Hesse, N., Jaramillo, D., Jost, B., Lash, S., Lonsdale, L., Mackens, M., Mutz, K., Potts, M., Sanchez, B., Snyder, W., Solley, W., Tarter, C., Wang, R., Williams, P., Perkins, S. L., Anderson, N., Arnold, A., Blais, P., Googe, J., Higdon, T. T., Hunt, C., Johnson, M., Miller, J., Moore, M., Morris, C. K., Morris, C., Oelrich, S., Oliver, K., Seitz, V., Whetstone, J., Doft, B. H., Bedel, J., Bergren, R., Borthwick, A., Conrad, P., Fec, A., Fulwylie, C., Ingram, W., Latham, S., Lester, G., Liu, J., Lobes, L., Lucko, N. M., Mechling, H., Merlotti, L., McBroom, K., Olsen, K., Puskas, D., Rath, P., Schmucker, M., Schueckler, L., Schultz, C., Shultz, H., Steinberg, D., Vyas, A., Whale, K., Yeckel, K., Orth, D. H., Arredondo, L. S., Brown, S., Ciscato, B. J., Civantos, J. M., Figliulo, C., Hasan, S., Kosinski, B., Muir, D., Nelson, K., Packo, K., Pollack, J. S., Rezaei, K., Shelton, G., Townsend-Patrick, S., Walsh, M., Richard McDonald, H., Ansari, N., Bye, A., Fu, A. D., Grout, S., Indermill, C., Johnson, R. N., Michael Jumper, J., Linares, S., Lujan, B. J., Munden, A., Persons, M., Rodriguez, R., Rose, J. M., Teske, B., Urias, Y., Young, S., Dreyer, R. F., Daniel, H., Connaughton, M., Handelman, I., Hobbs, S., Hoerner, C., Hudson, D., Kopfer, M., Lee, M., Lemley, C., Logan, J., Ma, C., Mallet, C., Milliron, A., Peters, M., Wohlsein, H., Pearlman, J. A., Andrews, M., Bartlett, M., Carlson, N., Cox, E., Equi, R., Gonzalez, M., Griffin, S., Hogue, F., Kennedy, L., Kryuchkov, L., Lopez, C., Lopez, D., Luevano, B., McKenna, E., Patel, A., Reed, B., Secor, N., Sison, I. R., Tsai, T., Varghis, N., Waller, B., Wendel, R., Yebra, R., Roth, D. B., Deinzer, J., Fine, H., Green, F., Green, S., Keyser, B., Leff, S., Leviton, A., Martir, A., Mosenthine, K., Muscle, S., Okoren, L., Parker, S., Prenner, J., Price, N., Rogers, D., Rosas, L., Schlosser, A., Studenko, L., Tantum, T., Wheatley, H., Trese, M. T., Aaberg, T., Bezaire, D., Bridges, C., Bryant, D., Capone, A., Coleman, M., Consolo, C., Cook, C., Dulong, C., Garretson, B., Grooten, T., Hammersley, J., Hassan, T., Jessick, H., Jones, N., Kinsman, C., Krumlauf, J., Lewis, S., Locke, H., Margherio, A., Markus, D., Marsh, T., Neal, S., Noffke, A., Oh, K., Pence, C., Preston, L., Raphaelian, P., Regan, V. R., Roberts, P., Ruby, A., Sarrafizadeh, R., Scherf, M., Scott, S., Sneed, S., Staples, L., Terry, B., Trese, M. T., Videtich, J., Williams, G., Zajechowski, M., Joseph, D. P., Blinder, K., Boyd, L., Buckley, S., Crow, M., Dinatale, A., Engelbrecht, N., Forke, B., Gabel, D., Grand, G., Grillion-Cerone, J., Holekamp, N., Kelly, C., Nobel, G., Pepple, K., Raeber, M., Kumar Rao, P., Ressel, T., Schremp, S., Sgorlon, M., Shears, S., Thomas, M., Timma, C., Vaughn, A., Walters, C., Weeks, R., Wehmeier, J., Wright, T., Berinstein, D. M., Ayyad, A., Barazi, M. K., Bickhart, E., Brady, T., Byank, L., Cronise, A., Denny, V., Dunn, C., Flory, M., Frantz, R., Garfinkel, R. A., Gilbert, W., Lai, M. M., Melamud, A., Newgen, J., Newton, S., Oliver, D., Osman, M., Sanders, R., Von Fricken, M., Dugel, P., Arenas, S., Balea, G., Bartoli, D., Bucci, J., Cornelius, J. A., Dickens, S., Doherty, D., Dunlap, H., Goldenberg, D., Jamal, K., Jimenez, N., Kavanagh, N., Kunimoto, D., Martin, J., Miner, J., Mobley, S., Park, D., Quinlan, E., Sipperley, J., Slagle, C., Smith, D., Yafchak, M., Yager, R., Flaxel, C. J., Bailey, S., Francis, P., Howell, C., Hwang, T., Ira, S., Klein, M., Lauer, A., Liesegang, T., Lundquist, A., Nolte, S., Nolte, S. K., Pickell, S., Pope, S., Rossi, J., Schain, M., Steinkamp, P., Toomey, M. D., Vahrenwald, D., West, K., Hubbard, B., Andelman, S., Bergstrom, C., Brower, J., Cribbs, B., Curtis, L., Dobbs, J., Dubois, L., Gaultney, J., Gibbs, D., Jordan, D., Leef, D., Martin, D. F., Myles, R., Olsen, T., Schwent, B., Srivastava, S., Waldron, R., Antoszyk, A. N., Balasubramaniam, U., Brooks, D., Brown, J., Browning, D., Clark, L., Ennis, S., Held, S., Helms, J. V., Herby, J., Karow, A., Leotaud, P., Massimino, C., McClain, D., McOwen, M., Mindel, J., Pereira, C., Pierce, R., Powers, M., Price, A., Rohrer, J., Sanders, J., Avery, R. L., Avery, K., Basefsky, J., Beckner, L., Castellarin, A., Couvillion, S., Giust, J., Giust, M., Nasir, M., Pieramici, D., Rabena, M., Risard, S., See, R., Smith, J., Wan, L., Bakri, S. J., Abu-Yaghi, N., Barkmeier, A., Berg, K., Burrington, J., Edwards, A., Goddard, S., Howard, S., Iezzi, R., Lewison, D., Link, T., McCannel, C. A., Overend, J., Pach, J., Ruszczyk, M., Shultz, R., Stephan, C., Vogen, D., Bradford, R. H., Bergman, V., Burris, R., Butt, A., Daniels, B., Dwiggins, C., Fransen, S., Guerrero, T., Haivala, D., Harris, A., Icks, S., Kingsley, R., Redden, L., Richmond, R., Ross, B., White, K., Youngberg, M., Topping, T. M., Chong, S., Ciotti, M., Cleary, T., Corey, E., Donovan, D., Frederick, A., Freese, L., Graham, M., Gud, N., Howard, T., Jones, M., Morley, M., Moses, K., Stone, J., Ty, R., Wiegand, T., Williams, L., Winder, B., Awh, C. C., Amonette, M., Arrindell, E., Beck, D., Busbee, B., Dilback, A., Downs, S., Guidry, A., Gutow, G., Hardin, J., Hines, S., Hutchins, E., Lacivita, K., Lester, A., Malott, L., McCain, M., Miracle, J., Moffat, K., Palazzotta, L., Robinson, K., Sonkin, P., Travis, A., Wallace, R. T., Winters, K. J., Wray, J., Harris, A. E., Bunnell, M., Crooks, K., Fitzgerald, R., Javid, C., Kew, C., Kill, E., Kline, P., Kreienkamp, J., Martinez, M., Ann Moore, R., Saavedra, E., Taylor, L., Walsh, M., Wilson, L., Ciulla, T. A., Coyle, E., Harrington, T., Harris, C., Hood, C., Kerr, I., Maturi, R., Moore, D., Morrow, S., Savage, J., Sink, B., Steele, T., Thukral, N., Wilburn, J., Walker, J. P., Banks, J., Ciampaglia, D., Dyshanowitz, D., Frederick, J., Tom Ghuman, A., Grodin, R., Kiesel, C., Knips, E., McCue, J., Ortiz, M., Peters, C., Raskauskas, P., Schoeman, E., Sharma, A., Wing, G., Youngblood, R., Chandra, S. R., Altaweel, M., Blodi, B., Burke, K., Dietzman, K. A., Gottlieb, J., Knutson, G., Krolnik, D., Michael Nork, T., Olson, S., Peterson, J., Reed, S., Soderling, B., Somers, G., Stevens, T., Wealti, A., Bearelly, S., Branchaud, B., Bryant, J. W., Crowell, S., Fekrat, S., Gammage, M., Harrison, C., Jones, S., McClain, N., McCuen, B., Mruthyunjaya, P., Queen, J., Sarin, N., Skalak, C., Skelly, M., Suner, I., Tomany, R., Welch, L., Park, S. S., Cassidy, A., Chandra, K., Good, I., Imson, K., Kaur, S., Metzler, H., Morse, L., Redenbo, E., Salvador, M., Telander, D., Thomas, M., Wallace, C., Barr, C. C., Battcher, A., Bottorff, M., Chasteen, M., Clark, K., Denning, D., Schoen, D., Schultz, A., Tempel, E., Wheeler, L., Whittington, G. K., Stone, T. W., Blevins, T., Buck, M., Cruz, L., Heath, W., Holcomb, D., Isernhagen, R., Kidd, T., Kitchens, J., Sears, C., Slade, E., Van Arsdall, J., Vanhoose, B., Wolfe, J., Wood, W., Zilis, J., Crooks, C., Disney, L., Liu, M., Petty, S., Sall, S., Folk, J. C., Aly, T., Brotherton, A., Critser, D., Hinz, C. J., Karakas, S., Kirschner, V., Lester, C., Montague, C., Russell, S., Stockman, H., Taylor, B., Verdick, R., Walshire, J., Thompson, J. T., Connell, B., Constantine, M., Davis, J. L., Holsapple, G., Hunter, L., Lenane, C. N., Mitchell, R., Russel, L., Sjaarda, R., Brown, D. M., Benz, M., Burns, L., Carranza, J. G., Fish, R., Goates, D., Hay, S., Jeffers, T., Kegley, E., Kubecka, D., McGilvra, S., Richter, B., Sneed, V., Stoever, C., Tellez, I., Wong, T., Kim, I., Andreoli, C., Barresi, L., Brett, S., Callahan, C., Capaccioli, K., Carli, W., Coppola, M., Emmanuel, N., Evans, C., Fagan, A., Grillo, M., Head, J., Kieser, T., Lee, E., Lord, U., Miretsky, E., Palitsch, K., Petrin, T., Reader, L., Reznichenko, S., Robertson, M., Smith, J., Vavvas, D., Wells, J., Cahill, C., Lloyd Clark, W., Henry, K., Johnson, D., Miller, P., Oliver, L., Spivey, R., Swinford, T., Taylor, M., Lambert, M., Chase, K., Fredrickson, D., Khawly, J., Lazarte, V., Lowd, D., Miller, P., Willis, A., Ferrone, P. J., Almonte, M., Arnott, R., Aviles, I., Carbon, S., Chitjian, M., Damore, K., Elliott, C., Fastenberg, D., Golub, B., Graham, K., Lavorna, A., Murphy, L., Palomo, A., Puglisi, C., Rhee, D., Romero, J., Rosenblatt, B., Salcedo, G., Schlameuss, M., Shakin, E., Sookhai, V., Kaiser, R., Affel, E., Brown, G., Centinaro, C., Fine, D., Fineman, M., Formoso, M., Garg, S., Grande, L., Herbert, C., Ho, A., Hsu, J., Jay, M., Lavetsky, L., Liebenbaum, E., Maguire, J., Monsonego, J., O'Connor, L., Pierce, L., Regillo, C., Rosario, M., Spirn, M., Vander, J., Walsh, J., Davidorf, F. H., Barnett, A., Chang, S., Christoforidis, J., Elliott, J., Justice, H., Letson, A., McKinney, K., Perry, J., Salerno, J. A., Savage, S., Shelley, S., Singerman, L. J., Coney, J., Dubois, J., Dubois, K., Greanoff, G., Himmelman, D., Ilc, M., McNamara, E., Novak, M., Pendergast, S., Rath, S., Smith-Brewer, S., Tanner, V., Weiss, D. E., Zegarra, H., Halperin, L., Aramayo, P., Dhalla, M., Fernandez, B., Fernandez, C., Lopez, J., Lopez, M., Mariano, J., Murphy, K., Sherley, C., Veksler, R., Rahhal, F., Babikian, R., Boyer, D., Hami, S., Kessinger, J., Kurokouchi, J., Mukarram, S., Pachman, S., Protacio, E., Sierra, J., Tabandeh, H., Zamboni, A., Elman, M., Belz, J., Butcher, T., Cain, T., Coffey, T., Firestone, D., Gore, N., Singletary, P., Sotirakos, P., Starr, J., Meredith, T. A., Barnhart, C. J., Cantrell, D., Esquejo-Leon, R., Houghton, O., Kaur, H., Ndure, F., Glatzer, R., Joffe, L., Schindler, R., Fine, S. L., Katz, M., Brightwell-Arnold, M., Glaser, R., Hall, J., Harkins, S., Huang, J., Khvatov, A., McWilliams, K., Peskin, E., Pistilli, M., Ryan, S., Schnader, A., Afrani-Sakyi, J., Balsley, B., Bennett, L. S., Brooks, A., Brower-Lingsch, A., Bruce, L., Busian, D., Choong, J., Cloaninger, L., DeCroos, F. C., Dubois, E., El-Dairi, M., Gach, S., Hall, K., Hawks, T., Huang, C., Heydary, C., Ho, A., Kini, S., McCall, M., Muhammad, D., Nicholson, J., Rieves, P., Shields, K., Specker, A., Stinnett, S., Subramaniam, S., Tenbrink, P., Towe, A., Welch, K., Williams, N., Winter, K., Young, E., Alexander, J., Flannagan, E., Martin, E. R., Parker, C., Sepielli, K., Shannon, T., Whearry, C., Redford, M., Kopfer, M. R., Ferris, F. L., Dupont, J., Friedman, L. M., Bressler, S. B., Demets, D. L., Friedlander, M., Johnson, M. W., Lindblad, A., Losordo, D. W. & Miller, F. G., Sep 1 2015, In: Ophthalmology. 122, 9, p. 1846-1853.e5

    Research output: Contribution to journalArticlepeer-review

    78 Scopus citations
  • 2014

    No clinically significant association between CFH and ARMS2 genotypes and response to nutritional supplements: AREDS report number 38

    Chew, E. Y., Klein, M. L., Clemons, T. E., Agrón, E., Ratnapriya, R., Edwards, A. O., Fritsche, L. G., Swaroop, A. & Abecasis, G. R., Nov 1 2014, In: Ophthalmology. 121, 11, p. 2173-2180 8 p.

    Research output: Contribution to journalArticlepeer-review

    58 Scopus citations
  • Prevalence of anti-retinal autoantibodies in different stages of Age-related macular degeneration

    Adamus, G., Chew, E. Y., Ferris, F. L. & Klein, M. L., Dec 8 2014, In: BMC ophthalmology. 14, 1, 154.

    Research output: Contribution to journalArticlepeer-review

    19 Scopus citations
  • Quantitative optical coherence tomography angiography of choroidal neovascularization in age-related macular degeneration

    Jia, Y., Bailey, S. T., Wilson, D. J., Tan, O., Klein, M. L., Flaxel, C. J., Potsaid, B., Liu, J. J., Lu, C. D., Kraus, M. F., Fujimoto, J. G. & Huang, D., Jul 2014, In: Ophthalmology. 121, 7, p. 1435-1444 10 p.

    Research output: Contribution to journalArticlepeer-review

    520 Scopus citations
  • Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration

    Ratnapriya, R., Zhan, X., Fariss, R. N., Branham, K. E., Zipprer, D., Chakarova, C. F., Sergeev, Y. V., Campos, M. M., Othman, M., Friedman, J. S., Maminishkis, A., Waseem, N. H., Brooks, M., Rajasimha, H. K., Edwards, A. O., Lotery, A., Klein, B. E., Truitt, B. J., Li, B., Schaumberg, D. A. & 47 others, Morgan, D. J., Morrison, M. A., Souied, E., Tsironi, E. E., Grassmann, F., Fishman, G. A., Silvestri, G., Scholl, H. P. N., Kim, I. K., Ramke, J., Tuo, J., Merriam, J. E., Merriam, J. C., Park, K. H., Olson, L. M., Farrer, L. A., Johnson, M. P., Peachey, N. S., Lathrop, M., Baron, R. V., Igo, R. P., Klein, R., Hagstrom, S. A., Kamatani, Y., Martin, T. M., Jiang, Y., Conley, Y., Sahel, J. A., Zack, D. J., Chan, C. C., Pericak-Vance, M. A., Jacobson, S. G., Gorin, M. B., Klein, M. L., Allikmets, R., Iyengar, S. K., Weber, B. H., Haines, J. L., Léveillard, T., Deangelis, M. M., Stambolian, D., Weeks, D. E., Bhattacharya, S. S., Chew, E. Y., Heckenlively, J. R., Abecasis, G. R. & Swaroop, A., Nov 1 2014, In: Human molecular genetics. 23, 21, p. 5827-5837 11 p.

    Research output: Contribution to journalArticlepeer-review

    33 Scopus citations
  • Risk of geographic atrophy in the comparison of age-related macular degeneration treatments trials

    Grunwald, J. E., Daniel, E., Huang, J., Ying, G. S., Maguire, M. G., Toth, C. A., Jaffe, G. J., Fine, S. L., Blodi, B., Klein, M. L., Martin, A. A., Hagstrom, S. A. & Martin, D. F., Jan 2014, In: Ophthalmology. 121, 1, p. 150-161 12 p.

    Research output: Contribution to journalArticlepeer-review

    332 Scopus citations
  • Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression AREDS2 report no. 3

    Chew, E. Y., Clemons, T. E., SanGiovanni, J. P., Danis, R. P., Ferris, F. L., Elman, M. J., Antoszyk, A. N., Ruby, A. J., Orth, D., Bressler, S. B., Fish, G. E., Hubbard, G. B., Klein, M. L., Chandra, S. R., Blodi, B. A., Domalpally, A., Friberg, T., Wong, W. T., Rosenfeld, P. J., Agrón, E. & 3 others, Toth, C. A., Bernstein, P. S. & Sperduto, R. D., Feb 2014, In: JAMA ophthalmology. 132, 2, p. 142-149 8 p.

    Research output: Contribution to journalArticlepeer-review

    199 Scopus citations
  • 2013

    Baseline predictors for one-year visual outcomes with ranibizumab or bevacizumab for neovascular age-related macular degeneration

    Ying, G. S., Huang, J., Maguire, M. G., Jaffe, G. J., Grunwald, J. E., Toth, C., Daniel, E., Klein, M., Pieramici, D., Wells, J. & Martin, D. F., Jan 2013, In: Ophthalmology. 120, 1, p. 122-129 8 p.

    Research output: Contribution to journalArticlepeer-review

    189 Scopus citations
  • Genetic determinants of macular pigments in women the carotenoids in age-related eye disease study

    Meyers, K. J., Johnson, E. J., Bernstein, P. S., Iyengar, S. K., Engelman, C. D., Karki, C. K., Liu, Z., Igo, R. P., Truitt, B., Klein, M. L., Snodderly, D. M., Blodi, B. A., Gehrs, K. M., Sarto, G. E., Wallace, R. B., Robinson, J., LeBlanc, E. S., Hageman, G., Tinker, L. & Mares, J. A., 2013, In: Investigative Ophthalmology and Visual Science. 54, 3, p. 2333-2345 13 p.

    Research output: Contribution to journalArticlepeer-review

    59 Scopus citations
  • Genetic evidence for role of carotenoids in age-related macular degeneration in the carotenoids in age-related eye disease study (CAREDS)

    Meyers, K. J., Mares, J. A., Igo, R. P., Truitt, B., Liu, Z., Millen, A. E., Klein, M., Johnson, E. J., Engelman, C. D., Karki, C. K., Blodi, B., Gehrs, K., Tinker, L., Wallace, R., Robinson, J., LeBlanc, E. S., Sarto, G., Bernstein, P. S., SanGiovanni, J. P. & Iyengar, S. K., Dec 17 2013, In: Investigative Ophthalmology and Visual Science. 55, 1, p. 587-599 13 p.

    Research output: Contribution to journalArticlepeer-review

    78 Scopus citations
  • Lutein/zeaxanthin for the treatment of age-related cataract: AREDS2 randomized trial report no. 4

    Chew, E. Y., SanGiovanni, J. P., Ferris, F. L., Wong, W. T., Agron, E., Clemons, T. E., Sperduto, R., Danis, R., Chandra, S. R., Blodi, B. A., Domalpally, A., Elman, M. J., Antoszyk, A. N., Ruby, A. J., Orth, D., Bressler, S. B., Fish, G. E., Hubbard, G. B., Klein, M. L., Friberg, T. R. & 3 others, Rosenfeld, P. J., Toth, C. A. & Bernstein, P., Jul 2013, In: JAMA ophthalmology. 131, 7, p. 843-850 8 p.

    Research output: Contribution to journalArticlepeer-review

    83 Scopus citations
  • Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: The Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial

    Chew, E. Y., Clemons, T. E., SanGiovanni, J. P., Danis, R., Ferris, F. L., Elman, M., Antoszyk, A., Ruby, A., Orth, D., Bressler, S., Fish, G., Hubbard, B., Klein, M., Chandra, S., Blodi, B., Domalpally, A., Friberg, T., Wong, W., Rosenfeld, P., Agron, E. & 3 others, Toth, C., Bernstein, P. & Sperdut, R., May 15 2013, In: JAMA - Journal of the American Medical Association. 309, 19, p. 2005-2015 11 p.

    Research output: Contribution to journalArticlepeer-review

    681 Scopus citations
  • Pharmacogenetics for genes associated with age-related macular degeneration in the comparison of AMD treatments trials (CATT)

    Hagstrom, S. A., Ying, G. S., Pauer, G. J. T., Sturgill-Short, G. M., Huang, J., Callanan, D. G., Kim, I. K., Klein, M. L., Maguire, M. G. & Martin, D. F., Mar 2013, In: Ophthalmology. 120, 3, p. 593-599 7 p.

    Research output: Contribution to journalArticlepeer-review

    110 Scopus citations
  • Seven new loci associated with age-related macular degeneration

    Fritsche, L. G., Chen, W., Schu, M., Yaspan, B. L., Yu, Y., Thorleifsson, G., Zack, D. J., Arakawa, S., Cipriani, V., Ripke, S., Igo, R. P., Buitendijk, G. H. S., Sim, X., Weeks, D. E., Guymer, R. H., Merriam, J. E., Francis, P. J., Hannum, G., Agarwal, A., Armbrecht, A. M. & 136 others, Audo, I., Aung, T., Barile, G. R., Benchaboune, M., Bird, A. C., Bishop, P. N., Branham, K. E., Brooks, M., Brucker, A. J., Cade, W. H., Cain, M. S., Campochiaro, P. A., Chan, C. C., Cheng, C. Y., Chew, E. Y., Chin, K. A., Chowers, I., Clayton, D. G., Cojocaru, R., Conley, Y. P., Cornes, B. K., Daly, M. J., Dhillon, B., Edwards, A. O., Evangelou, E., Fagerness, J., Ferreyra, H. A., Friedman, J. S., Geirsdottir, A., George, R. J., Gieger, C., Gupta, N., Hagstrom, S. A., Harding, S. P., Haritoglou, C., Heckenlively, J. R., Holz, F. G., Hughes, G., Ioannidis, J. P. A., Ishibashi, T., Joseph, P., Jun, G., Kamatani, Y., Katsanis, N., N Keilhauer, C., Khan, J. C., Kim, I. K., Kiyohara, Y., Klein, B. E. K., Klein, R., Kovach, J. L., Kozak, I., Lee, C. J., Lee, K. E., Lichtner, P., Lotery, A. J., Meitinger, T., Mitchell, P., Mohand-Saïd, S., Moore, A. T., Morgan, D. J., Morrison, M. A., Myers, C. E., Naj, A. C., Nakamura, Y., Okada, Y., Orlin, A., Ortube, M. C., Othman, M. I., Pappas, C., Park, K. H., Pauer, G. J. T., Peachey, N. S., Poch, O., Priya, R. R., Reynolds, R., Richardson, A. J., Ripp, R., Rudolph, G., Ryu, E., Sahel, J. A., Schaumberg, D. A., Scholl, H. P. N., Schwartz, S. G., Scott, W. K., Shahid, H., Sigurdsson, H., Silvestri, G., Sivakumaran, T. A., Smith, R. T., Sobrin, L., Souied, E. H., Stambolian, D. E., Stefansson, H., Sturgill-Short, G. M., Takahashi, A., Tosakulwong, N., Truitt, B. J., Tsironi, E. E., Uitterlinden, A. G., Van Duijn, C. M., Vijaya, L., Vingerling, J. R., Vithana, E. N., Webster, A. R., Wichmann, H. E., Winkler, T. W., Wong, T. Y., Wright, A. F., Zelenika, D., Zhang, M., Zhao, L., Zhang, K., Klein, M. L., Hageman, G. S., Lathrop, G. M., Stefansson, K., Allikmets, R., Baird, P. N., Gorin, M. B., Wang, J. J., Klaver, C. C. W., Seddon, J. M., Pericak-Vance, M. A., Iyengar, S. K., Yates, J. R. W., Swaroop, A., Weber, B. H. F., Kubo, M., Deangelis, M. M., Léveillard, T., Thorsteinsdottir, U., Haines, J. L., Farrer, L. A., Heid, I. M. & Abecasis, G. R., Apr 2013, In: Nature genetics. 45, 4, p. 433-439 7 p.

    Research output: Contribution to journalArticlepeer-review

    531 Scopus citations
  • 2012

    Hypomethylation of the IL17RC Promoter Associates with Age-Related Macular Degeneration

    Wei, L., Liu, B., Tuo, J., Shen, D., Chen, P., Li, Z., Liu, X., Ni, J., Dagur, P., Sen, H. N., Jawad, S., Ling, D., Park, S., Chakrabarty, S., Meyerle, C., Agron, E., Ferris, F. L., Chew, E. Y., McCoy, J. P., Blum, E. & 6 others, Francis, P. J., Klein, M. L., Guymer, R. H., Baird, P. N., Chan, C. C. & Nussenblatt, R. B., Nov 29 2012, In: Cell Reports. 2, 5, p. 1151-1158 8 p.

    Research output: Contribution to journalArticlepeer-review

    107 Scopus citations
  • The related transcriptional enhancer factor-1 Isoform, TEAD4216, can repress vascular endothelial growth factor expression in mammalian cells

    Appukuttan, B., McFarland, T. J., Stempel, A., Kassem, J. B., Hartzell, M., Zhang, Y., Bond, D., West, K., Wilson, R., Stout, A., Pan, Y., Ilias, H., Robertson, K., Klein, M. L., Wilson, D., Smith, J. R. & Stout, J. T., Jun 22 2012, In: PloS one. 7, 6, e31260.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • 2011

    A 32 kb critical region excluding Y402H in CFH mediates risk for age-related macular degeneration

    Sivakumaran, T. A., Igo, R. P., Kidd, J. M., Itsara, A., Kopplin, L. J., Chen, W., Hagstrom, S. A., Peachey, N. S., Francis, P. J., Klein, M. L., Chew, E. Y., Ramprasad, V. L., Tay, W. T., Mitchell, P., Seielstad, M., Stambolian, D. E., Edwards, A. O., Lee, K. E., Leontiev, D. V., Jun, G. & 20 others, Wang, Y., Tian, L., Qiu, F., Henning, A. K., LaFramboise, T., Sen, P., Aarthi, M., George, R., Raman, R., Das, M. K., Vijaya, L., Kumaramanickavel, G., Wong, T. Y., Swaroop, A., Abecasis, G. R., Klein, R., Klein, B. E. K., Nickerson, D. A., Eichler, E. E. & Iyengar, S. K., Oct 12 2011, In: PloS one. 6, 10, e25598.

    Research output: Contribution to journalArticlepeer-review

    39 Scopus citations
  • 30 Scopus citations
  • Complement component C5a Promotes Expression of IL-22 and IL-17 from Human T cells and its Implication in Age-related Macular Degeneration

    Liu, B., Wei, L., Meyerle, C., Tuo, J., Sen, H. N., Li, Z., Chakrabarty, S., Agron, E., Chan, C. C., Klein, M. L., Chew, E., Ferris, F. & Nussenblatt, R. B., Jul 15 2011, In: Journal of translational medicine. 9, 1, 111.

    Research output: Contribution to journalArticlepeer-review

    105 Scopus citations
  • Evidence of association of APOE with age-related macular degeneration - a pooled analysis of 15 studies

    Mckay, G. J., Patterson, C. C., Chakravarthy, U., Dasari, S., Klaver, C. C., Vingerling, J. R., Ho, L., de Jong, P. T. V. M., Fletcher, A. E., Young, I. S., Seland, J. H., Rahu, M., Soubrane, G., Tomazzoli, L., Topouzis, F., Vioque, J., Hingorani, A. D., Sofat, R., Dean, M., Sawitzke, J. & 30 others, Seddon, J. M., Peter, I., Webster, A. R., Moore, A. T., Yates, J. R. W., Cipriani, V., Fritsche, L. G., Weber, B. H. F., Keilhauer, C. N., Lotery, A. J., Ennis, S., Klein, M. L., Francis, P. J., Stambolian, D., Orlin, A., Gorin, M. B., Weeks, D. E., Kuo, C. L., Swaroop, A., Othman, M., Kanda, A., Chen, W., Abecasis, G. R., Wright, A. F., Hayward, C., Baird, P. N., Guymer, R. H., Attia, J., Thakkinstian, A. & Silvestri, G., Dec 2011, In: Human mutation. 32, 12, p. 1407-1416 10 p.

    Research output: Contribution to journalArticlepeer-review

    86 Scopus citations
  • Healthy lifestyles related to subsequent prevalence of age-related macular degeneration

    Mares, J. A., Voland, R. P., Sondel, S. A., Millen, A. E., LaRowe, T., Moeller, S. M., Klein, M. L., Blodi, B. A., Chappell, R. J., Tinker, L., Ritenbaugh, C., Gehrs, K. M., Sarto, G. E., Johnson, E., Snodderly, D. M. & Wallace, R. B., Apr 2011, In: Archives of ophthalmology. 129, 4, p. 470-480 11 p.

    Research output: Contribution to journalArticlepeer-review

    98 Scopus citations
  • Risk assessment model for development of advanced age-related macular degeneration

    Klein, M. L., Francis, P. J., Ferris, F. L., Hamon, S. C. & Clemons, T. E., Dec 2011, In: Archives of ophthalmology. 129, 12, p. 1543-1550 8 p.

    Research output: Contribution to journalArticlepeer-review

    48 Scopus citations
  • Vitamin D status and early age-related macular degeneration in postmenopausal women

    Millen, A. E., Voland, R., Sondel, S. A., Parekh, N., Horst, R. L., Wallace, R. B., Hageman, G. S., Chappell, R., Blodi, B. A., Klein, M. L., Gehrs, K. M., Sarto, G. E. & Mares, J. A., Apr 2011, In: Archives of ophthalmology. 129, 4, p. 481-489 9 p.

    Research output: Contribution to journalArticlepeer-review

    90 Scopus citations
  • 2010

    Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

    Chen, W., Stambolian, D., Edwards, A. O., Branham, K. E., Othman, M., Jakobsdottir, J., Tosakulwong, N., Pericak-Vance, M. A., Campochiaro, P. A., Klein, M. L., Tan, P. L., Conley, Y. P., Kanda, A., Kopplin, L., Li, Y., Augustaitis, K. J., Karoukis, A. J., Scott, W. K., Agarwal, A., Kovach, J. L. & 46 others, Schwartz, S. G., Postel, E. A., Brooks, M., Baratz, K. H., Brown, W. L., Brucker, A. J., Orlin, A., Brown, G., Ho, A., Regillo, C., Donoso, L., Tian, L., Kaderli, B., Hadley, D., Hagstrom, S. A., Peachey, N. S., Klein, R., Klein, B. E. K., Gotoh, N., Yamashiro, K., Ferris, F., Fagerness, J. A., Reynolds, R., Farrer, L. A., Kim, I. K., Miller, J. W., Cortón, M., Carracedo, A., Sanchez-Salorio, M., Pugh, E. W., Doheny, K. F., Brion, M., DeAngelis, M. M., Weeks, D. E., Zack, D. J., Chew, E. Y., Heckenlively, J. R., Yoshimura, N., Iyengar, S. K., Francis, P. J., Katsanis, N., Seddon, J. M., Haines, J. L., Gorin, M. B., Abecasis, G. R. & Swaroop, A., Apr 20 2010, In: Proceedings of the National Academy of Sciences of the United States of America. 107, 16, p. 7401-7406 6 p.

    Research output: Contribution to journalArticlepeer-review

    389 Scopus citations
  • Genome-wide association identifies SKIV2L and MYRIP as protective factors for age-related macular degeneration

    Kopplin, L. J., Igo, R. P., Wang, Y., Sivakumaran, T. A., Hagstrom, S. A., Peachey, N. S., Francis, P. J., Klein, M. L., Sangiovanni, J. P., Chew, E. Y., Pauer, G. J. T., Sturgill, G. M., Joshi, T., Tian, L., Xi, Q., Henning, A. K., Lee, K. E., Klein, R., Klein, B. E. K. & Iyengar, S. K., Dec 2010, In: Genes and Immunity. 11, 8, p. 609-621 13 p.

    Research output: Contribution to journalArticlepeer-review

    48 Scopus citations
  • Natural History of Drusenoid Pigment Epithelial Detachment in Age-Related Macular Degeneration: Age-Related Eye Disease Study Report No. 28

    Cukras, C., Agrón, E., Klein, M. L., Ferris, F. L., Chew, E. Y., Gensler, G. & Wong, W. T., Mar 2010, In: Ophthalmology. 117, 3, p. 489-499 11 p.

    Research output: Contribution to journalArticlepeer-review

    92 Scopus citations
  • Progression of geographic atrophy and genotype in age-related macular degeneration

    Klein, M. L., Ferris, F. L., Francis, P. J., Lindblad, A. S., Chew, E. Y., Hamon, S. C. & Ott, J., 2010, In: Ophthalmology. 117, 8, p. 1554-1559.e1

    Research output: Contribution to journalArticlepeer-review

    53 Scopus citations
  • 2009

    Change in area of geographic atrophy in the age-related eye disease study: AREDS report number 26

    Lindblad, A. S., Lloyd, P. C., Clemons, T. E., Gensler, G. R., Ferris, F. L., Klein, M. L. & Armstrong, J. R., Sep 2009, In: Archives of ophthalmology. 127, 9, p. 1168-1174 7 p.

    Research output: Contribution to journalArticlepeer-review

    142 Scopus citations
  • Mitochondrial DNA variants of respiratory complex I that uniquely characterize haplogroup T2 are associated with increased risk of age-related macular degeneration

    SanGiovanni, J. P., Arking, D. E., Iyengar, S. K., Elashoff, M., Clemons, T. E., Reed, G. F., Henning, A. K., Sivakumaran, T. A., Xu, X., DeWan, A., Agrón, E., Rochtchina, E., Sue, C. M., Wang, J. J., Mitchell, P., Hoh, J., Francis, P. J., Klein, M. L., Chew, E. Y. & Chakravarti, A., May 12 2009, In: PloS one. 4, 5, e5508.

    Research output: Contribution to journalArticlepeer-review

    73 Scopus citations
  • Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss

    Francis, P. J., Hamon, S. C., Ott, J., Weleber, R. G. & Klein, M. L., May 2009, In: Journal of medical genetics. 46, 5, p. 300-307 8 p.

    Research output: Contribution to journalArticlepeer-review

    107 Scopus citations
  • 2008

    Associations between age-related nuclear cataract and lutein and zeaxanthin in the diet and serum in the carotenoids in the age-related eye disease study (CAREDS), an ancillary study of the Women's Health Initiative

    Moeller, S. M., Voland, R., Tinker, L., Blodi, B. A., Klein, M. L., Gehrs, K. M., Johnson, E. J., Snodderly, D. M., Wallace, R. B., Chappell, R. J., Parekh, N., Ritenbaugh, C. & Mares, J. A., Mar 2008, In: Archives of ophthalmology. 126, 3, p. 354-364 11 p.

    Research output: Contribution to journalArticlepeer-review

    82 Scopus citations
  • CFH and LOC387715/ARMS2 Genotypes and Treatment with Antioxidants and Zinc for Age-Related Macular Degeneration

    Klein, M. L., Francis, P. J., Rosner, B., Reynolds, R., Hamon, S. C., Schultz, D. W., Ott, J. & Seddon, J. M., Jun 2008, In: Ophthalmology. 115, 6, p. 1019-1025 7 p.

    Research output: Contribution to journalArticlepeer-review

    133 Scopus citations
  • Clinicopathologic correlation of retinal angiomatous proliferation

    Monson, D. M., Smith, J. R., Klein, M. L. & Wilson, D. J., Dec 2008, In: Archives of ophthalmology. 126, 12, p. 1664-1668 5 p.

    Research output: Contribution to journalArticlepeer-review

    43 Scopus citations
  • Joint effects of polymorphisms in the HTRA1, LOC387715/ARMS2, and CFH genes on AMD in a Caucasian population

    Francis, P. J., Zhang, H., DeWan, A., Hoh, J. & Klein, M. L., Aug 4 2008, In: Molecular vision. 14, p. 1395-1400 6 p.

    Research output: Contribution to journalArticlepeer-review

    60 Scopus citations