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  • 16 Similar Profiles
Macular Degeneration Medicine & Life Sciences
Genes Medicine & Life Sciences
Therapeutics Medicine & Life Sciences
Eye Diseases Medicine & Life Sciences
Visual Acuity Medicine & Life Sciences
Light Coagulation Medicine & Life Sciences
Choroidal Neovascularization Medicine & Life Sciences
Geographic Atrophy Medicine & Life Sciences

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Projects 1979 2016

Macular Degeneration
Genetic Predisposition to Disease
Joints
Genes
Phenotype

GENETICS OF AGE RELATED MACULAR DEGENERATION

Klein, M.

National Institutes of Health

8/1/987/31/08

Project: Research projectResearch Project

Macular Degeneration
Genes
Therapeutics
Genetic Association Studies
Pedigree

PARALLEL COMPUTER FOR MEMBRANE AND PROTEIN SIMULATIONS

Klein, M.

National Institutes of Health

9/30/939/29/94

Project: Research projectBiomedical Research Support Shared Instrumentation Grants

Membrane Proteins
Proteins
Nuclear magnetic resonance
Membranes
Processing

CENTRAL VEIN OCCLUSION STUDY - PARTICIPATING CENTER

Klein, M.

National Institutes of Health

3/1/882/28/94

Project: Research projectCooperative Clinical Research--Cooperative Agreements, Research Project--Cooperative Agreements

Veins
Macular Edema
Reading
Therapeutics
Retinal Vein

MACULAR PHOTOCOAGULATION STUDY

Klein, M.

National Institutes of Health

1/1/797/31/85

Project: Research projectResearch Project--Cooperative Agreements

Research Output 1974 2017

  • 12120 Citations
  • 57 h-Index
  • 149 Article
  • 1 Chapter

Bivariate analysis of age-related macular degeneration progression using genetic risk scores

Ding, Y., Liu, Y., Yan, Q., Fritsche, L. G., Cook, R. J., Clemons, T., Ratnapriya, R., Klein, M. L., Abecasis, G. R., Swaroop, A., Chew, E. Y., Weeks, D. E. & Chen, W. May 1 2017 In : Genetics. 206, 1, p. 119-133 15 p.

Research output: Research - peer-reviewArticle

Macular Degeneration
Eye Diseases
Disease Progression
Demography
Blindness

CLINICOPATHOLOGIC CORRELATION of RETINAL ANGIOMATOUS PROLIFERATION TREATED with RANIBIZUMAB

Skalet, A. H., Miller, A. K., Klein, M. L., Lauer, A. K. & Wilson, D. J. Aug 1 2017 In : Retina. 37, 8, p. 1620-1624 5 p.

Research output: Research - peer-reviewArticle

Ranibizumab
Optical Coherence Tomography
Bruch Membrane
Retinal Pigment Epithelium
Macular Degeneration
3 Citations

Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits

Grassmann, F. , Kiel, C. , Zimmermann, M. E. , Gorski, M. , Grassmann, V. , Stark, K. , Heid, I. M. , Weber, B. H. F. , Fritsche, L. G. , Igl, W. , Bailey, J. N. C. , Sengupta, S. , Bragg-Gresham, J. L. , Burdon, K. P. , Hebbring, S. J. , Wen, C. , Kim, I. K. , Cho, D. , Zack, D. , Souied, E. & 146 others Scholl, H. P. N., Bala, E., Lee, K. E., Hunter, D. J., Sardell, R. J., Mitchell, P., Merriam, J. E., Cipriani, V., Hoffman, J. D., Schick, T., Lechanteur, Y. T. E., Guymer, R. H., Johnson, M. P., Jiang, Y., Stanton, C. M., Buitendijk, G. H. S., Zhan, X., Kwong, A. M., Boleda, A., Brooks, M., Gieser, L., Ratnapriya, R., Branham, K. E., Foerster, J. R., Heckenlively, J. R., Othman, M. I., Vote, B. J., Liang, H. H., Souzeau, E., McAllister, I. L., Isaacs, T., Hall, J., Lake, S., Mackey, D. A., Constable, I. J., Craig, J. E., Kitchner, T. E., Yang, Z., Su, Z., Luo, H., Chen, D., Ouyang, H., Flagg, K., Lin, D., Mao, G., Ferreyra, H., von Strachwitz, C. N., Wolf, A., Brandl, C., Rudolph, G., Olden, M., Morrison, M. A., Morgan, D. J., Schu, M., Ahn, J., Silvestri, G., Tsironi, E. E., Park, K. H., Farrer, L. A., Orlin, A., Brucker, A., Li, M., Curcio, C. A., Mohand-Saïd, S., Sahel, J. A., Audo, I., Benchaboune, M., Cree, A. J., Rennie, C. A., Goverdhan, S. V., Grunin, M., Hagbi-Levi, S., Campochiaro, P., Katsanis, N., Holz, F. G., Blond, F., Blanché, H., Deleuze, J. F., Igo, R. P., Truitt, B., Peachey, N. S., Meuer, S. M., Myers, C. E., Moore, E. L., Klein, R., Hauser, M. A., Postel, E. A., Courtenay, M. D., Schwartz, S. G., Kovach, J. L., Scott, W. K., Liew, G., Tan, A. G., Gopinath, B., Merriam, J. C., Smith, R. T., Khan, J. C., Shahid, H., Moore, A. T., McGrath, J. A., Laux, R., Brantley, M. A., Agarwal, A., Ersoy, L., Caramoy, A., Langmann, T., Saksens, N. T. M., de Jong, E. K., Hoyng, C. B., Cain, M. S., Richardson, A. J., Martin, T. M., Blangero, J., Weeks, D. E., Dhillon, B., van Duijn, C. M., Doheny, K. F., Romm, J., Klaver, C. C. W., Hayward, C., Gorin, M. B., Klein, M. L., Baird, P. N., den Hollander, A. I., Fauser, S., Yates, J. R. W., Allikmets, R., Wang, J. J., Schaumberg, D. A., Klein, B. E. K., Hagstrom, S. A., Chowers, I., Lotery, A. J., Léveillard, T., Zhang, K., Brilliant, M. H., Hewitt, A. W., Swaroop, A., Chew, E. Y., Pericak-Vance, M. A., DeAngelis, M., Stambolian, D., Haines, J. L., Iyengar, S. K., Abecasis, G. R. & International AMD Genomics Consortium (IAMDGC) Mar 27 2017 In : Genome Medicine. 9, 1, 29

Research output: Research - peer-reviewArticle

Genetic Pleiotropy
Macular Degeneration
Autoimmune Diseases
Genome
Lipid Metabolism Disorders
2 Citations

Recombinant haplotypes narrow the ARMS2/HTRA1 association signal for age-related macular degeneration

Grassmann, F. , Heid, I. M. , Weber, B. H. F. , Fritsche, L. G. , Igl, W. , Bailey, J. N. , Grassmann, F. , Sengupta, S. , Bragg-Gresham, J. L. , Burdon, K. P. , Hebbring, S. J. , Wen, C. , Gorski, M. , Kim, I. K. , Cho, D. , Zack, D. , Souied, E. , Scholl, H. P. , Bala, E. , Lee, K. E. & 146 others Hunter, D. J., Sardell, R. J., Mitchell, P., Merriam, J. E., Cipriani, V., Hoffman, J. D., Schick, T., Lechanteur, Y. T., Guymer, R. H., Johnson, M. P., Jiang, Y., Stanton, C. M., Buitendijk, G. H., Zhan, X., Kwong, A. M., Boleda, A., Brooks, M., Gieser, L., Ratnapriya, R., Branham, K. E., Foerster, J. R., Heckenlively, J. R., Othman, M. I., Vote, B. J., Liang, H. H., Souzeau, E., McAllister, I. L., Isaacs, T., Hall, J., Lake, S., Mackey, D. A., Constable, I. J., Craig, J. E., Kitchner, T. E., Yang, Z., Su, Z., Luo, H., Chen, D., Ouyang, H., Flagg, K., Lin, D., Mao, G., Ferreyra, H., Stark, K., von Strachwitz, C. N., Wolf, A., Brandl, C., Rudolph, G., Olden, M., Morrison, M. A., Morgan, D. J., Schu, M., Ahn, J., Silvestri, G., Tsironi, E. E., Park, K. H., Farrer, L. A., Orlin, A., Brucker, A., Li, M., Curcio, C. A., Mohand-Saïd, S., Sahel, J. A., Audo, I., Benchaboune, M., Cree, A. J., Rennie, C. A., Goverdhan, S. V., Grunin, M., Hagbi-Levi, S., Campochiaro, P., Katsanis, N., Holz, F. G., Blond, F., Blanché, H., Deleuze, J. F., Igo, R. P., Truitt, B., Peachey, N. S., Meuer, S. M., Myers, C. E., Moore, E. L., Klein, R., Hauser, M. A., Postel, E. A., Courtenay, M. D., Schwartz, S. G., Kovach, J. L., Scott, W. K., Liew, G., Tan, A. G., Gopinath, B., Merriam, J. C., Smith, R. T., Khan, J. C., Shahid, H., Moore, A. T., McGrath, J. A., Laux, R., Brantley, M., Agarwal, A., Ersoy, L., Caramoy, A., Langmann, T., Saksens, N. T., de Jong, E. K., Hoyng, C. B., Cain, M. S., Richardson, A. J., Martin, T. M., Blangero, J., Weeks, D. E., Dhillon, B., van Duijn, C. M., Doheny, K. F., Romm, J., Klaver, C. C., Hayward, C., Gorin, M. B., Klein, M. L., Baird, P. N., den Hollander, A. I., Fauser, S., Yates, J. R., Allikmets, R., Wang, J. J., Schaumberg, D. A., Klein, B. E., Hagstrom, S. A., Chowers, I., Lotery, A. J., Léveillard, T., Zhang, K., Brilliant, M. H., Hewitt, A. W., Swaroop, A., Chew, E. Y., Pericak-Vance, M. A., Deangelis, M., Stambolian, D., Haines, J. L., Iyengar, S. K., Weber, B. H., Abecasis, G. R., Heid, I. M. & International AMD Genomics Consortium (IAMDGC) Feb 1 2017 In : Genetics. 205, 2, p. 919-924 6 p.

Research output: Research - peer-reviewArticle

Macular Degeneration
Haplotypes
Genes
Blindness
Genomics
101 Citations

A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants

Fritsche, L. G. , Igl, W. , Bailey, J. N. C. , Grassmann, F. , Sengupta, S. , Bragg-Gresham, J. L. , Burdon, K. P. , Hebbring, S. J. , Wen, C. , Gorski, M. , Kim, I. K. , Cho, D. , Zack, D. , Souied, E. , Scholl, H. P. N. , Bala, E. , ELee, K. , Hunter, D. J. , Sardell, R. J. , Mitchell, P. & 142 others Merriam, J. E., Cipriani, V., Hoffman, J. D., Schick, T., Lechanteur, Y. T. E., Guymer, R. H., Johnson, M. P., Jiang, Y., Stanton, C. M., Buitendijk, G. H. S., Zhan, X., Kwong, A. M., Boleda, A., Brooks, M., Gieser, L., Ratnapriya, R., Branham, K. E., Foerster, J. R., Heckenlively, J. R., Othman, M. I., Vote, B. J., Liang, H. H., Souzeau, E., McAllister, I. L., Isaacs, T., Hall, J., Lake, S., Mackey, D. A., Constable, I. J., Craig, J. E., Kitchner, T. E., Yang, Z., Su, Z., Luo, H., Chen, D., Ouyang, H., Flagg, K., Lin, D., Mao, G., Ferreyra, H., Stark, K., Von Strachwitz, C. N., Wolf, A., Brandl, C., Rudolph, G., Olden, M., Morrison, M. A., Morgan, D. J., Schu, M., Ahn, J., Silvestri, G., Tsironi, E. E., Park, K. H., Farrer, L. A., Orlin, A., Brucker, A., Li, M., Curcio, C. A., Mohand-Sa'd, S., Sahel, J. A., Audo, I., Benchaboune, M., Cree, A. J., Rennie, C. A., Goverdhan, S. V., Grunin, M., Hagbi-Levi, S., Campochiaro, P., Katsanis, N., Holz, F. G., Blond, F., Blanché, H., Deleuze, J. F. O., Igo, R. P., Truitt, B., Peachey, N. S., Meuer, S. M., Myers, C. E., Moore, E. L., Klein, R., Hauser, M. A., Postel, E. A., Courtenay, M. D., Schwartz, S. G., Kovach, J. L., Scott, W. K., Liew, G., Tan, A. G., Gopinath, B., Merriam, J. C., Smith, R. T., Khan, J. C., Shahid, H., Moore, A. T., McGrath, J. A., Laux, R., Brantley, M. A., Agarwal, A., Ersoy, L., Caramoy, A., Langmann, T., Saksens, N. T. M., Jong, E. K., Hoyng, C. B., Cain, M. S., Richardson, A. J., Martin, T. M., Blangero, J., Weeks, D. E., Dhillon, B., Van Duijn, C. M., Doheny, K. F., Romm, J., Klaver, C. C. W., Hayward, C., Gorin, M. B., Klein, M. L., Baird, P. N., Den Hollander, A. I., Fauser, S., WYates, J. R., Allikmets, R., Wang, J. J., Schaumberg, D. A., Klein, B. E. K., Hagstrom, S. A., Chowers, I., Lotery, A. J., Léveillard, T., Zhang, K., Brilliant, M. H., Hewitt, A. W., Swaroop, A., Chew, E. Y., Pericak-Vance, M. A., DeAngelis, M., Stambolian, D., Haines, J. L., Iyengar, S. K., Weber, B. H. F., Abecasis, G. R. & Heid, I. M. Feb 1 2016 In : Nature Genetics. 48, 2, p. 134-143 10 p.

Research output: Research - peer-reviewArticle

Genome-Wide Association Study
Macular Degeneration
Genes
Genetic Loci
Blindness