Michael Chapman

Professor

  • 4111 Citations
  • 34 h-Index
1983 …2019
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Fingerprint Dive into the research topics where Michael Chapman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Arginine Kinase Medicine & Life Sciences
Dependovirus Medicine & Life Sciences
Canine Parvovirus Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Viruses Chemical Compounds
Capsid Medicine & Life Sciences
Proteins Medicine & Life Sciences
Rhinovirus Medicine & Life Sciences

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Projects 1983 2017

electron microscopy
assembly
parameterization
ribosomes
computer programs
Enzymes
Arginine Kinase
Nuclear magnetic resonance
Substrates
Dynamic models
Dependovirus
Viral Genes
Genetic Therapy
Cryoelectron Microscopy
Epitopes

Research Output 1986 2019

  • 4111 Citations
  • 34 h-Index
  • 102 Article

Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Meyer, N. L., Hu, G., Davulcu, O., Xie, Q., Noble, A. J., Yoshioka, C., Gingerich, D. S., Trzynka, A., David, L., Stagg, S. M. & Chapman, M., May 22 2019, In : eLife. 8

Research output: Contribution to journalArticle

Open Access
Gene therapy
Dependovirus
Viruses
Genetic Therapy
Electron Microscope Tomography
22 Citations (Scopus)

Adeno-associated virus (AAV) assembly-activating protein is not an essential requirement for capsid assembly of AAV serotypes 4, 5, and 11

Earley, L. F., Powers, J. M., Adachi, K., Baumgart, J. T., Meyer, N. L., Xie, Q., Chapman, M. & Nakai, H., 2017, In : Journal of Virology. 91, 3, e01980-16.

Research output: Contribution to journalArticle

Dependovirus
Virus Assembly
capsid
Capsid
serotypes
22 Citations (Scopus)

Adenoassociated virus (AAV) serotypes have distinctive interactions with domains of the cellular AAV receptor

Pillay, S., Zou, W., Cheng, F., Puschnik, A. S., Meyer, N. L., Ganaie, S. S., Deng, X., Wosen, J. E., Davulcu, O., Yan, Z., Engelhardt, J. F., Brown, K. E., Chapman, M., Qiu, J. & Carette, J. E., Sep 1 2017, In : Journal of Virology. 91, 18, e00391-17.

Research output: Contribution to journalArticle

Dependovirus
Virus Receptors
serotypes
Viruses
viruses
1 Citation (Scopus)

Elevated μs-ms timescale backbone dynamics in the transition state analog form of arginine kinase

Davulcu, O., Peng, Y., Brüschweiler, R., Skalicky, J. J. & Chapman, M., Apr 11 2017, (Accepted/In press) In : Journal of Structural Biology.

Research output: Contribution to journalArticle

Arginine Kinase
Enzymes
Magnetic Resonance Spectroscopy
Catalysis
Arginine
9 Citations (Scopus)

The 2.8 Å Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide

Xie, Q., Spear, J. M., Noble, A. J., Sousa, D. R., Meyer, N. L., Davulcu, O., Zhang, F., Linhardt, R. J., Stagg, S. M. & Chapman, M., Jun 16 2017, In : Molecular Therapy - Methods and Clinical Development. 5, p. 1-12 12 p.

Research output: Contribution to journalArticle

Heparinoids
Dependovirus
Electron Microscopy
Polysaccharides
Heparin