Maureen Hoatlin

Associate Professor

  • 5207 Citations
  • 35 h-Index
1985 …2013

Research output per year

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Research Output

  • 5207 Citations
  • 35 h-Index
  • 57 Article
  • 4 Review article
  • 2 Comment/debate
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Article
2013

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

Shen, H., Fridley, B. L., Song, H., Lawrenson, K., Cunningham, J. M., Ramus, S. J., Cicek, M. S., Tyrer, J., Stram, D., Larson, M. C., Köbel, M., Ziogas, A., Zheng, W., Yang, H. P., Wu, A. H., Wozniak, E. L., Ling Woo, Y., Winterhoff, B., Wik, E., Whittemore, A. S. & 148 others, Wentzensen, N., Palmieri Weber, R., Vitonis, A. F., Vincent, D., Vierkant, R. A., Vergote, I., Van Den Berg, D., Van Altena, A. M., Tworoger, S. S., Thompson, P. J., Tessier, D. C., Terry, K. L., Teo, S. H., Templeman, C., Stram, D. O., Southey, M. C., Sieh, W., Siddiqui, N., Shvetsov, Y. B., Shu, X. O., Shridhar, V., Wang-Gohrke, S., Severi, G., Schwaab, I., Salvesen, H. B., Rzepecka, I. K., Runnebaum, I. B., Anne Rossing, M., Rodriguez-Rodriguez, L., Risch, H. A., Renner, S. P., Poole, E. M., Pike, M. C., Phelan, C. M., Pelttari, L. M., Pejovic, T., Paul, J., Orlow, I., Zawiah Omar, S., Olson, S. H., Odunsi, K., Nickels, S., Nevanlinna, H., Ness, R. B., Narod, S. A., Nakanishi, T., Moysich, K. B., Monteiro, A. N. A., Moes-Sosnowska, J., Modugno, F., Menon, U., McLaughlin, J. R., McGuire, V., Matsuo, K., Mat Adenan, N. A., Massuger, L. F. A. G., Lurie, G., Lundvall, L., Lubiński, J., Lissowska, J., Levine, D. A., Leminen, A., Lee, A. W., Le, N. D., Lambrechts, S., Lambrechts, D., Kupryjanczyk, J., Krakstad, C., Konecny, G. E., Krüger Kjaer, S., Kiemeney, L. A., Kelemen, L. E., Keeney, G. L., Karlan, B. Y., Karevan, R., Kalli, K. R., Kajiyama, H., Ji, B. T., Jensen, A., Jakubowska, A., Iversen, E., Hosono, S., Høgdall, C. K., Høgdall, E., Hoatlin, M., Hillemanns, P., Heitz, F., Hein, R., Harter, P., Halle, M. K., Hall, P., Gronwald, J., Gore, M., Goodman, M. T., Giles, G. G., Gentry-Maharaj, A., Garcia-Closas, M., Flanagan, J. M., Fasching, P. A., Ekici, A. B., Edwards, R., Eccles, D., Easton, D. F., Dürst, M., Du Bois, A., Dörk, T., Doherty, J. A., Despierre, E., Dansonka-Mieszkowska, A., Cybulski, C., Cramer, D. W., Cook, L. S., Chen, X., Charbonneau, B., Chang-Claude, J., Campbell, I., Butzow, R., Bunker, C. H., Brueggmann, D., Brown, R., Brooks-Wilson, A., Brinton, L. A., Bogdanova, N., Block, M. S., Benjamin, E., Beesley, J., Beckmann, M. W., Bandera, E. V., Baglietto, L., Bacot, F., Armasu, S. M., Antonenkova, N., Anton-Culver, H., Aben, K. K., Liang, D., Wu, X., Lu, K., Hildebrandt, M. A. T., Schildkraut, J. M., Sellers, T. A., Huntsman, D., Berchuck, A., Chenevix-Trench, G., Gayther, S. A., Pharoah, P. D. P., Laird, P. W., Goode, E. L. & Leigh Pearce, C., 2013, In : Nature communications. 4, 1628.

Research output: Contribution to journalArticle

109 Scopus citations

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Pharoah, P. D. P., Tsai, Y. Y., Ramus, S. J., Phelan, C. M., Goode, E. L., Lawrenson, K., Buckley, M., Fridley, B. L., Tyrer, J. P., Shen, H., Weber, R., Karevan, R., Larson, M. C., Song, H., Tessier, D. C., Bacot, F., Vincent, D., Cunningham, J. M., Dennis, J., Dicks, E. & 148 others, Aben, K. K., Anton-Culver, H., Antonenkova, N., Armasu, S. M., Baglietto, L., Bandera, E. V., Beckmann, M. W., Birrer, M. J., Bloom, G., Bogdanova, N., Brenton, J. D., Brinton, L. A., Brooks-Wilson, A., Brown, R., Butzow, R., Campbell, I., Carney, M. E., Carvalho, R. S., Chang-Claude, J., Chen, Y. A., Chen, Z., Chow, W. H., Cicek, M. S., Coetzee, G., Cook, L. S., Cramer, D. W., Cybulski, C., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J. A., Dörk, T., Du Bois, A., Dürst, M., Eccles, D., Edwards, R., Ekici, A. B., Fasching, P. A., Fenstermacher, D., Flanagan, J., Gao, Y. T., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G., Gjyshi, A., Gore, M., Gronwald, J., Guo, Q., Halle, M. K., Harter, P., Hein, A., Heitz, F., Hillemanns, P., Hoatlin, M., Høgdall, E., Høgdall, C. K., Hosono, S., Jakubowska, A., Jensen, A., Kalli, K. R., Karlan, B. Y., Kelemen, L. E., Kiemeney, L. A., Kjaer, S. K., Konecny, G. E., Krakstad, C., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Le, N. D., Lee, N., Lee, J., Leminen, A., Lim, B. K., Lissowska, J., Lubiński, J., Lundvall, L., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S., Orlow, I., Paul, J., Pejovic, T., Pelttari, L. M., Permuth-Wey, J., Pike, M. C., Poole, E. M., Qu, X., Risch, H. A., Rodriguez-Rodriguez, L., Rossing, M. A., Rudolph, A., Runnebaum, I., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shen, H., Shridhar, V., Shu, X. O., Sieh, W., Southey, M. C., Spellman, P., Tajima, K., Teo, S. H., Terry, K. L., Thompson, P. J., Timorek, A., Tworoger, S. S., Van Altena, A. M., Van Den Berg, D., Vergote, I., Vierkant, R. A., Vitonis, A. F., Wang-Gohrke, S., Wentzensen, N., Whittemore, A. S., Wik, E., Winterhoff, B., Woo, Y. L., Wu, A. H., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Goodman, M. T., Hall, P., Easton, D. F., Pearce, C. L., Berchuck, A., Chenevix-Trench, G., Iversen, E., Monteiro, A. N. A., Gayther, S. A., Schildkraut, J. M. & Sellers, T. A., Apr 2013, In : Nature genetics. 45, 4, p. 362-370 9 p.

Research output: Contribution to journalArticle

237 Scopus citations

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

Permuth-Wey, J., Lawrenson, K., Shen, H. C., Velkova, A., Tyrer, J. P., Chen, Z., Lin, H. Y., Ann Chen, Y., Tsai, Y. Y., Qu, X., Ramus, S. J., Karevan, R., Lee, J., Lee, N., Larson, M. C., Aben, K. K., Anton-Culver, H., Antonenkova, N., Antoniou, A. C., Armasu, S. M. & 158 others, Bacot, F., Baglietto, L., Bandera, E. V., Barnholtz-Sloan, J., Beckmann, M. W., Birrer, M. J., Bloom, G., Bogdanova, N., Brinton, L. A., Brooks-Wilson, A., Brown, R., Butzow, R., Cai, Q., Campbell, I., Chang-Claude, J., Chanock, S., Chenevix-Trench, G., Cheng, J. Q., Cicek, M. S., Coetzee, G. A., Cook, L. S., Couch, F. J., Cramer, D. W., Cunningham, J. M., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J. A., Dörk, T., Du Bois, A., Dürst, M., Easton, D. F., Eccles, D., Edwards, R., Ekici, A. B., Fasching, P. A., Fenstermacher, D. A., Flanagan, J. M., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G. G., Glasspool, R. M., Gonzalez-Bosquet, J., Goodman, M. T., Gore, M., Górski, B., Gronwald, J., Hall, P., Halle, M. K., Harter, P., Heitz, F., Hillemanns, P., Hoatlin, M., Høgdall, C. K., Høgdall, E., Hosono, S., Jakubowska, A., Jensen, A., Jim, H., Kalli, K. R., Karlan, B. Y., Kaye, S. B., Kelemen, L. E., Kiemeney, L. A., Kikkawa, F., Konecny, G. E., Krakstad, C., Krüger Kjaer, S., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Lancaster, J. M., Le, N. D., Leminen, A., Levine, D. A., Liang, D., Kiong Lim, B., Lin, J., Lissowska, J., Lu, K. H., Lubiński, J., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Nedergaard, L., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S. H., Orlow, I., Paul, J., Pearce, C. L., Pejovic, T., Pelttari, L. M., Pike, M. C., Poole, E. M., Raska, P., Renner, S. P., Risch, H. A., Rodriguez-Rodriguez, L., Anne Rossing, M., Rudolph, A., Runnebaum, I. B., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shridhar, V., Shu, X. O., Shvetsov, Y. B., Sieh, W., Song, H., Southey, M. C., Spiewankiewicz, B., Stram, D., Sutphen, R., Teo, S. H., Terry, K. L., Tessier, D. C., Thompson, P. J., Tworoger, S. S., Van Altena, A. M., Vergote, I., Vierkant, R. A., Vincent, D., Vitonis, A. F., Wang-Gohrke, S., Palmieri Weber, R., Wentzensen, N., Whittemore, A. S., Wik, E., Wilkens, L. R., Winterhoff, B., Ling Woo, Y., Wu, A. H., Xiang, Y. B., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Phelan, C. M., Iversen, E., Schildkraut, J. M., Berchuck, A., Fridley, B. L., Goode, E. L., Pharoah, P. D. P., Monteiro, A. N. A., Sellers, T. A. & Gayther, S. A., 2013, In : Nature communications. 4, 1627.

Research output: Contribution to journalArticle

74 Scopus citations

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Bojesen, S. E., Pooley, K. A., Johnatty, S. E., Beesley, J., Michailidou, K., Tyrer, J. P., Edwards, S. L., Pickett, H. A., Shen, H. C., Smart, C. E., Hillman, K. M., Mai, P. L., Lawrenson, K., Stutz, M. D., Lu, Y., Karevan, R., Woods, N., Johnston, R. L., French, J. D., Chen, X. & 417 others, Weischer, M., Nielsen, S. F., Maranian, M. J., Ghoussaini, M., Ahmed, S., Baynes, C., Bolla, M. K., Wang, Q., Dennis, J., McGuffog, L., Barrowdale, D., Lee, A., Healey, S., Lush, M., Tessier, D. C., Vincent, D., Bacot, F., Vergote, I., Lambrechts, S., Despierre, E., Risch, H. A., González-Neira, A., Rossing, M. A., Pita, G., Doherty, J. A., Álvarez, N., Larson, M. C., Fridley, B. L., Schoof, N., Chang-Claude, J., Cicek, M. S., Peto, J., Kalli, K. R., Broeks, A., Armasu, S. M., Schmidt, M. K., Braaf, L. M., Winterhoff, B., Nevanlinna, H., Konecny, G. E., Lambrechts, D., Rogmann, L., Guénel, P., Teoman, A., Milne, R. L., Garcia, J. J., Cox, A., Shridhar, V., Burwinkel, B., Marme, F., Hein, R., Sawyer, E. J., Haiman, C. A., Wang-Gohrke, S., Andrulis, I. L., Moysich, K. B., Hopper, J. L., Odunsi, K., Lindblom, A., Giles, G. G., Brenner, H., Simard, J., Lurie, G., Fasching, P. A., Carney, M. E., Radice, P., Wilkens, L. R., Swerdlow, A., Goodman, M. T., Brauch, H., Garcia-Closas, M., Hillemanns, P., Winqvist, R., Dürst, M., Devilee, P., Runnebaum, I., Jakubowska, A., Lubinski, J., Mannermaa, A., Butzow, R., Bogdanova, N. V., Dörk, T., Pelttari, L. M., Zheng, W., Leminen, A., Anton-Culver, H., Bunker, C. H., Kristensen, V., Ness, R. B., Muir, K., Edwards, R., Meindl, A., Heitz, F., Matsuo, K., Du Bois, A., Wu, A. H., Harter, P., Teo, S. H., Schwaab, I., Shu, X. O., Blot, W., Hosono, S., Kang, D., Nakanishi, T., Hartman, M., Yatabe, Y., Hamann, U., Karlan, B. Y., Sangrajrang, S., Kjaer, S. K., Gaborieau, V., Jensen, A., Eccles, D., Høgdall, E., Shen, C. Y., Brown, J., Woo, Y. L., Shah, M., Azmi, M. A. N., Luben, R., Omar, S. Z., Czene, K., Vierkant, R. A., Nordestgaard, B. G., Flyger, H., Vachon, C., Olson, J. E., Wang, X., Levine, D. A., Rudolph, A., Weber, R. P., Flesch-Janys, D., Iversen, E., Nickels, S., Schildkraut, J. M., Silva, I. D. S., Cramer, D. W., Gibson, L., Terry, K. L., Fletcher, O., Vitonis, A. F., Van Der Schoot, C. E., Poole, E. M., Hogervorst, F. B. L., Tworoger, S. S., Liu, J., Bandera, E. V., Li, J., Olson, S. H., Humphreys, K., Orlow, I., Blomqvist, C., Rodriguez-Rodriguez, L., Aittomäki, K., Salvesen, H. B., Muranen, T. A., Wik, E., Brouwers, B., Krakstad, C., Wauters, E., Halle, M. K., Wildiers, H., Kiemeney, L. A., Mulot, C., Aben, K. K., Laurent-Puig, P., Altena, A. M., Truong, T., Massuger, L. F. A. G., Benitez, J., Pejovic, T., Perez, J. I. A., Hoatlin, M., Zamora, M. P., Cook, L. S., Balasubramanian, S. P., Kelemen, L. E., Schneeweiss, A., Le, N. D., Sohn, C., Brooks-Wilson, A., Tomlinson, I., Kerin, M. J., Miller, N., Cybulski, C., Henderson, B. E., Menkiszak, J., Schumacher, F., Wentzensen, N., Le Marchand, L., Yang, H. P., Mulligan, A. M., Glendon, G., Engelholm, S. A., Knight, J. A., Høgdall, C. K., Apicella, C., Gore, M., Tsimiklis, H., Song, H., Southey, M. C., Jager, A., Den Ouweland, A. M. W., Brown, R., Martens, J. W. M., Flanagan, J. M., Kriege, M., Paul, J., Margolin, S., Siddiqui, N., Severi, G., Whittemore, A. S., Baglietto, L., McGuire, V., Stegmaier, C., Sieh, W., Müller, H., Arndt, V., Labrèche, F., Gao, Y. T., Goldberg, M. S., Yang, G., Dumont, M., McLaughlin, J. R., Hartmann, A., Ekici, A. B., Beckmann, M. W., Phelan, C. M., Lux, M. P., Permuth-Wey, J., Peissel, B., Sellers, T. A., Ficarazzi, F., Barile, M., Ziogas, A., Ashworth, A., Gentry-Maharaj, A., Jones, M., Ramus, S. J., Orr, N., Menon, U., Pearce, C. L., Brüning, T., Pike, M. C., Ko, Y. D., Lissowska, J., Figueroa, J., Kupryjanczyk, J., Chanock, S. J., Dansonka-Mieszkowska, A., Jukkola-Vuorinen, A., Rzepecka, I. K., Pylkäs, K., Bidzinski, M., Kauppila, S., Hollestelle, A., Seynaeve, C., Tollenaar, R. A. E. M., Durda, K., Jaworska, K., Hartikainen, J. M., Kosma, V. M., Kataja, V., Antonenkova, N. N., Long, J., Shrubsole, M., Deming-Halverson, S., Lophatananon, A., Siriwanarangsan, P., Stewart-Brown, S., Ditsch, N., Lichtner, P., Schmutzler, R. K., Ito, H., Iwata, H., Tajima, K., Tseng, C. C., Stram, D. O., Van Den Berg, D., Yip, C. H., Ikram, M. K., Teh, Y. C., Cai, H., Lu, W., Signorello, L. B., Cai, Q., Noh, D. Y., Yoo, K. Y., Miao, H., Iau, P. T. C., Teo, Y. Y., McKay, J., Shapiro, C., Ademuyiwa, F., Fountzilas, G., Hsiung, C. N., Yu, J. C., Hou, M. F., Healey, C. S., Luccarini, C., Peock, S., Stoppa-Lyonnet, D., Peterlongo, P., Rebbeck, T. R., Piedmonte, M., Singer, C. F., Friedman, E., Thomassen, M., Offit, K., Hansen, T. V. O., Neuhausen, S. L., Szabo, C. I., Blanco, I., Garber, J., Narod, S. A., Weitzel, J. N., Montagna, M., Olah, E., Godwin, A. K., Yannoukakos, D., Goldgar, D. E., Caldes, T., Imyanitov, E. N., Tihomirova, L., Arun, B. K., Campbell, I., Mensenkamp, A. R., Van Asperen, C. J., Van Roozendaal, K. E. P., Meijers-Heijboer, H., Collée, J. M., Oosterwijk, J. C., Hooning, M. J., Rookus, M. A., Van Der Luijt, R. B., Os, T. A. M., Evans, D. G., Frost, D., Fineberg, E., Barwell, J., Walker, L., Kennedy, M. J., Platte, R., Davidson, R., Ellis, S. D., Cole, T., Bressac-De Paillerets, B., Buecher, B., Damiola, F., Faivre, L., Frenay, M., Sinilnikova, O. M., Caron, O., Giraud, S., Mazoyer, S., Bonadona, V., Caux-Moncoutier, V., Toloczko-Grabarek, A., Gronwald, J., Byrski, T., Spurdle, A. B., Bonanni, B., Zaffaroni, D., Giannini, G., Bernard, L., Dolcetti, R., Manoukian, S., Arnold, N., Engel, C., Deissler, H., Rhiem, K., Niederacher, D., Plendl, H., Sutter, C., Wappenschmidt, B., Borg, Å., Melin, B., Rantala, J., Soller, M., Nathanson, K. L., Domchek, S. M., Rodriguez, G. C., Salani, R., Kaulich, D. G., Tea, M. K., Paluch, S. S., Laitman, Y., Skytte, A. B., Kruse, T. A., Jensen, U. B., Robson, M., Gerdes, A. M., Ejlertsen, B., Foretova, L., Savage, S. A., Lester, J., Soucy, P., Kuchenbaecker, K. B., Olswold, C., Cunningham, J. M., Slager, S., Pankratz, V. S., Dicks, E., Lakhani, S. R., Couch, F. J., Hall, P., Monteiro, A. N. A., Gayther, S. A., Pharoah, P. D. P., Reddel, R. R., Goode, E. L., Greene, M. H., Easton, D. F., Berchuck, A., Antoniou, A. C., Chenevix-Trench, G. & Dunning, A. M., Apr 2013, In : Nature genetics. 45, 4, p. 371-384 14 p.

Research output: Contribution to journalArticle

363 Scopus citations
2012

A Ubiquitin-Binding Protein, FAAP20, Links RNF8-Mediated Ubiquitination to the Fanconi Anemia DNA Repair Network

Yan, Z., Guo, R., Paramasivam, M., Shen, W., Ling, C., Fox, D., Wang, Y., Oostra, A. B., Kuehl, J., Lee, D. Y., Takata, M., Hoatlin, M. E., Schindler, D., Joenje, H., de Winter, J. P., Li, L., Seidman, M. M. & Wang, W., Jul 13 2012, In : Molecular Cell. 47, 1, p. 61-75 15 p.

Research output: Contribution to journalArticle

49 Scopus citations

BRCAness profile of sporadic ovarian cancer predicts disease recurrence

Wysham, W. Z., Mhawech-Fauceglia, P., Li, H., Hays, L., Syriac, S., Skrepnik, T., Wright, J., Pande, N., Hoatlin, M. & Pejovic, T., Jan 11 2012, In : PloS one. 7, 1, e30042.

Research output: Contribution to journalArticle

43 Scopus citations
2011

Evidence for complete epistasis of null mutations in murine Fanconi anemia genes Fanca and Fancg

Van de Vrugt, H. J., Koomen, M., Bakker, S., Berns, M. A. D., Cheng, N. C., van der Valk, M. A., de Vries, Y., Rooimans, M. A., Oostra, A. B., Hoatlin, M. E., te Riele, H., Joenje, H. & Arwert, F., Dec 10 2011, In : DNA Repair. 10, 12, p. 1252-1261 10 p.

Research output: Contribution to journalArticle

7 Scopus citations
2010

A Histone-Fold Complex and FANCM Form a Conserved DNA-Remodeling Complex to Maintain Genome Stability

Yan, Z., Delannoy, M., Ling, C., Daee, D., Osman, F., Muniandy, P. A., Shen, X., Oostra, A. B., Du, H., Steltenpool, J., Lin, T., Schuster, B., Décaillet, C., Stasiak, A., Stasiak, A. Z., Stone, S., Hoatlin, M. E., Schindler, D., Woodcock, C. L., Joenje, H. & 8 others, Sen, R., de Winter, J. P., Li, L., Seidman, M. M., Whitby, M. C., Myung, K., Constantinou, A. & Wang, W., Mar 26 2010, In : Molecular Cell. 37, 6, p. 865-878 14 p.

Research output: Contribution to journalArticle

151 Scopus citations

Structure-specific recognition protein 1 facilitates microtubule growth and bundling required for mitosis

Zeng, S. X., Li, Y., Jin, Y., Zhang, Q., Keller, D. M., McQuaw, C. M., Barklis, E., Stone, S., Hoatlin, M., Zhao, Y. & Lu, H., Feb 2010, In : Molecular and cellular biology. 30, 4, p. 935-947 13 p.

Research output: Contribution to journalArticle

18 Scopus citations
2009

A novel cell-free screen identifies a potent inhibitor of the fanconi anemia pathway

Lanclais, I., Sobeck, A., Stone, S., LaChapelle, A. & Hoatlin, M. E., Feb 15 2009, In : International Journal of Cancer. 124, 4, p. 783-792 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

Landais, I., Hiddingh, S., McCarroll, M., Yang, C., Sun, A., Turker, M. S., Snyder, J. P. & Hoatlin, M. E., Dec 31 2009, In : Molecular Cancer. 8, 133.

Research output: Contribution to journalArticle

33 Scopus citations

The Fanconi anemia protein FANCM is controlled by FANCD2 and the ATR/ATM pathways

Sobeck, A., Stone, S., Landais, I., de Graaf, B. & Hoatlin, M. E., Sep 18 2009, In : Journal of Biological Chemistry. 284, 38, p. 25560-25568 9 p.

Research output: Contribution to journalArticle

30 Scopus citations

Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells

Zhang, H., Fraser, S. T., Papazoglu, C., Hoatlin, M. E. & Baron, M. H., Dec 2009, In : Stem Cells. 27, 12, p. 2884-2895 12 p.

Research output: Contribution to journalArticle

13 Scopus citations
2008

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

Wilson, J. B., Yamamoto, K., Marriott, A. S., Hussain, S., Sung, P., Hoatlin, M. E., Mathew, C. G., Takata, M., Thompson, L. H., Kupfer, G. M. & Jones, N. J., Jun 12 2008, In : Oncogene. 27, 26, p. 3641-3652 12 p.

Research output: Contribution to journalArticle

67 Scopus citations

Fanconi anemia proteins stabilize replication forks

Wang, L. C., Stone, S., Hoatlin, M. E. & Gautier, J., Dec 1 2008, In : DNA Repair. 7, 12, p. 1973-1981 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability

Xu, D., Guo, R., Sobeck, A., Bachrati, C. Z., Yang, J., Enomoto, T., Brown, G. W., Hoatlin, M. E., Hickson, I. D. & Wang, W., Oct 15 2008, In : Genes and Development. 22, 20, p. 2843-2855 13 p.

Research output: Contribution to journalArticle

130 Scopus citations
2007

DNA structure-induced recruitment and activation of the Fanconi anemia pathway protein FANCD2

Sobeck, A., Stone, S. & Hoatlin, M. E., Jun 2007, In : Molecular and cellular biology. 27, 12, p. 4283-4292 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

Ling, C., Ishiai, M., Ali, A. M., Medhurst, A. L., Neveling, K., Kalb, R., Yan, Z., Xue, Y., Oostra, A. B., Auerbach, A. D., Hoatlin, M. E., Schindler, D., Joenje, H., De Winter, J. P., Takata, M., Meetei, A. R. & Wang, W., Apr 18 2007, In : EMBO Journal. 26, 8, p. 2104-2114 11 p.

Research output: Contribution to journalArticle

110 Scopus citations

Identification, developmental expression and regulation of the Xenopus ortholog of human FANCG/XRCC9

Stone, S., Sobeck, A., van Kogelenberg, M., de Graaf, B., Joenje, H., Christian, J. & Hoatlin, M. E., Jul 1 2007, In : Genes to Cells. 12, 7, p. 841-851 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2006

Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks

Sobeck, A., Stone, S., Costanzo, V., De Graaf, B., Reuter, T., De Winter, J., Wallisch, M., Akkari, Y., Olson, S., Wang, W., Joenje, H., Christian, J. L., Lupardus, P. J., Cimprich, K. A., Gautier, J. & Hoatlin, M. E., Jan 2006, In : Molecular and cellular biology. 26, 2, p. 425-437 13 p.

Research output: Contribution to journalArticle

82 Scopus citations

The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC

Léveillé, F., Ferrer, M., Medhurst, A. L., Laghmani, E. H., Rooimans, M. A., Bier, P., Steltenpool, J., Titus, T. A., Postlethwait, J. H., Hoatlin, M. E., Joenje, H. & de Winter, J. P., May 10 2006, In : DNA Repair. 5, 5, p. 556-565 10 p.

Research output: Contribution to journalArticle

19 Scopus citations
2005

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

Meetei, A. R., Medhurst, A. L., Ling, C., Xue, Y., Singh, T. R., Bier, P., Steltenpool, J., Stone, S., Dokal, I., Mathew, C. G., Hoatlin, M., Joenje, H., De Winter, J. P. & Wang, W., Sep 2005, In : Nature genetics. 37, 9, p. 958-963 6 p.

Research output: Contribution to journalArticle

338 Scopus citations

BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

Yin, J., Sobeck, A., Xu, C., Meetei, A. R., Hoatlin, M., Li, L. & Wang, W., Apr 6 2005, In : EMBO Journal. 24, 7, p. 1465-1476 12 p.

Research output: Contribution to journalArticle

138 Scopus citations
2004

Heterogeneity in Fanconi anemia: Evidence for 2 new genetic subtypes

Levitus, M., Rooimans, M. A., Steltenpool, J., Cool, N. F. C., Oostra, A. B., Mathew, C. G., Hoatlin, M. E., Waisfisz, Q., Arwert, F., De Winter, J. P. & Joenje, H., Apr 1 2004, In : Blood. 103, 7, p. 2498-2503 6 p.

Research output: Contribution to journalArticle

191 Scopus citations

The Fanconi anemia gene product FANCF is a flexible adaptor protein

Léveillé, F., Blom, E., Medhurst, A. L., Bier, P., Laghmani, E. H., Johnson, M., Rooimans, M. A., Sobeck, A., Waisfisz, Q., Arwert, F., Patel, K. J., Hoatlin, M. E., Joenje, H. & De Winter, J. P., Sep 17 2004, In : Journal of Biological Chemistry. 279, 38, p. 39421-39430 10 p.

Research output: Contribution to journalArticle

53 Scopus citations

X-linked inheritance of Fanconi anemia complementation group B

Meetei, A. R., Levitus, M., Xue, Y., Medhurst, A. L., Zwaan, M., Ling, C., Rooimans, M. A., Bier, P., Hoatlin, M., Pals, G., De Winter, J. P., Wang, W. & Joenje, H., Nov 1 2004, In : Nature genetics. 36, 11, p. 1219-1224 6 p.

Research output: Contribution to journalArticle

228 Scopus citations
2003

A multiprotein nuclear complex connects fanconi anemia and bloom syndrome

Meetei, A. R., Sechi, S., Wallisch, M., Yang, D., Young, M. K., Joenje, H., Hoatlin, M. E. & Wang, W., May 2003, In : Molecular and cellular biology. 23, 10, p. 3417-3426 10 p.

Research output: Contribution to journalArticle

279 Scopus citations

A novel ubiquitin ligase is deficient in Fanconi anemia

Meetei, A. R., De Winter, J. P., Medhurst, A. L., Wallisch, M., Waisfisz, Q., Van de Vrugt, H. J., Oostra, A. B., Yan, Z., Ling, C., Bishop, C. E., Hoatlin, M. E., Joenje, H. & Wang, W., Oct 1 2003, In : Nature genetics. 35, 2, p. 165-170 6 p.

Research output: Contribution to journalArticle

446 Scopus citations

FANCD2 protein is expressed in proliferating cells of human tissues that are cancer-prone in Fanconi anaemia

Hölzel, M., van Diest, P. J., Bier, P., Wallisch, M., Hoatlin, M. E., Joenje, H. & de Winter, J. P., Oct 1 2003, In : Journal of Pathology. 201, 2, p. 198-203 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2

Ikeda, H., Matsushita, M., Waisfisz, Q., Kinoshita, A., Oostra, A. B., Nieuwint, A. W. M., De Winter, J. P., Hoatlin, M. E., Kawai, Y., Sasaki, M. S., D'Andrea, A. D., Kawakami, Y. & Joenje, H., May 15 2003, In : Cancer Research. 63, 10, p. 2688-2694 7 p.

Research output: Contribution to journalArticle

45 Scopus citations

Yeast two-hybrid screens imply involvement of fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport

Reuter, T. Y., Medhurst, A. L., Waisfisz, Q., Zhi, Y., Herterich, S., Hoehn, H., Gross, H. J., Joenje, H., Hoatlin, M. E., Mathew, C. G. & Huber, P. A. J., Oct 1 2003, In : Experimental Cell Research. 289, 2, p. 211-221 11 p.

Research output: Contribution to journalArticle

46 Scopus citations
2002

Characterization, expression and complex formation of the murine Fanconi anaemia gene product Fancg

Van De Vrugt, H. J., Koomen, M., Berns, M. A. D., De Vries, Y., Rooimans, M. A., Van Der Weel, L., Blom, E., De Groot, J., Schepers, R. J., Stone, S., Hoatlin, M. E., Cheng, N. C., Joenje, H. & Arwert, F., Apr 9 2002, In : Genes to Cells. 7, 3, p. 333-342 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

Fance: The link between Fanconi anaemia complex assembly and activity

Pace, P., Johnson, M., Tan, W. M., Mosedale, G., Sng, C., Hoatlin, M., De Winter, J., Joenje, H., Gergely, F. & Patel, K. J., Jul 1 2002, In : EMBO Journal. 21, 13, p. 3414-3423 10 p.

Research output: Contribution to journalArticle

132 Scopus citations

Fanconi anemia protein complex is a novel target of the IKK signalsome

Otsuki, T., Young, D. B., Sasaki, D. T., Pando, M. P., Li, J., Manning, A., Hoekstra, M., Hoatlin, M. E., Mercurio, F. & Liu, J. M., Aug 14 2002, In : Journal of cellular biochemistry. 86, 4, p. 613-623 11 p.

Research output: Contribution to journalArticle

23 Scopus citations

The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific

Dai, M. S., Chevallier, N., Stone, S., Heinrich, M. C., McConnell, M., Reuter, T., Broxmeyer, H. E., Licht, J. D., Lu, L. & Hoatlin, M. E., Jul 19 2002, In : Journal of Biological Chemistry. 277, 29, p. 26327-26334 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
2000

Aberrant Fanconi anaemia protein profiles in acute myeloid leukaemia cells

Xie, Y., De Winter, J. P., Waisfisz, Q., Nieuwint, A. W. M., Scheper, R. J., Arwert, F., Hoatlin, M. E., Ossenkoppele, G. J., Schuurhuis, G. J. & Joenje, H., Dec 1 2000, In : British Journal of Haematology. 111, 4, p. 1057-1064 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Cloning and characterization of murine fanconi anemia group A gene: Fanca protein is expressed in lymphoid tissues, testis, and ovary

Van De Vrugt, H. J., Cheng, N. C., De Vries, Y., Rooimans, M. A., De Groot, J., Scheper, R. J., Zhi, Y., Hoatlin, M. E., Joenje, H. & Arwert, F., Apr 6 2000, In : Mammalian Genome. 11, 4, p. 326-331 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

Posttranscriptional cell cycle-dependent regulation of human FANCC expression

Heinrich, M. C., Silvey, K. V., Stone, S., Zigler, A. J., Griffith, D. J., Montalto, M., Chai, L., Zhi, Y. & Hoatlin, M. E., Jun 15 2000, In : Blood. 95, 12, p. 3970-3977 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM

De Winter, J. P., Rooimans, M. A., Van Der Weel, L., Van Berkel, C. G. M., Alon, N., Bosnoyan-Collins, L., De Groot, J., Zhi, Y., Waisfisz, Q., Pronk, J. C., Arwert, F., Mathew, C. G., Scheper, R. J., Hoatlin, M. E., Buchwald, M. & Joenje, H., 2000, In : Nature genetics. 24, 1, p. 15-16 2 p.

Research output: Contribution to journalArticle

230 Scopus citations

The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

De Winter, J. P., Van Der Weel, L., De Groot, J., Stone, S., Waisfisz, Q., Arwert, F., Scheper, R. J., Kruyt, F. A. E., Hoatlin, M. E. & Joenje, H., Nov 1 2000, In : Human molecular genetics. 9, 18, p. 2665-2674 10 p.

Research output: Contribution to journalArticle

Open Access
171 Scopus citations
1999

A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF

Hoatlin, M. E., Yu, Z., Ball, H., Silvey, K., Melnick, A., Stone, S., Arai, S., Hawe, N., Owen, G., Zelent, A. & Licht, J. D., Dec 1 1999, In : Blood. 94, 11, p. 3737-3747 11 p.

Research output: Contribution to journalArticle

107 Scopus citations

A physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCA

Waisfisz, Q., De Winter, J. P., Kruyt, F. A. E., De Groot, J., Van Der Weel, L., Dijkmans, L. M., Zhi, Y., Arwert, F., Scheper, R. J., Youssoufian, H., Hoatlin, M. E. & Joenje, H., Aug 31 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 18, p. 10320-10325 6 p.

Research output: Contribution to journalArticle

123 Scopus citations

Spontaneous functional correction of homozygous Fanconi anaemia alleles reveals novel mechanistic basis for reverse mosaicism

Waisfisz, Q., Morgan, N. V., Savino, M., De Winter, J. P., Van Berkel, C. G. M., Hoatlin, M. E., Ianzano, L., Gibson, R. A., Arwert, F., Savoia, A., Mathew, C. G., Pronk, J. C. & Joenje, H., Aug 1999, In : Nature genetics. 22, 4, p. 379-383 5 p.

Research output: Contribution to journalArticle

155 Scopus citations
1998

An array of novel murine spleen focus-forming viruses that activate the erythropoietin receptor

Gomez-Lucia, E., Yu, Z., Nabavi, M., Zhang, W., Kabat, D. & Hoatlin, M. E., May 1998, In : Journal of virology. 72, 5, p. 3742-3750 9 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

DNA cross-linker-induced G2/M arrest in group C Fanconi anemia lymphoblasts reflects normal checkpoint function

Heinrich, M. C., Hoatlin, M. E., Zigler, A. J., Silvey, K. V., Bakke, A. C., Keeble, W. W., Zhi, Y., Reifsteck, C. A., Grompe, M., Brown, M. G., Magenis, R. E., Olson, S. B. & Bagby, G. C., Jan 1 1998, In : Blood. 91, 1, p. 275-287 13 p.

Research output: Contribution to journalArticle

Open Access
61 Scopus citations

Expression of the Fanconi anemia group C gene in hematopoietic cells is not influenced by oxidative stress, cross-linking agents, radiation, heat, or mitotic inhibitory factors

Tower, P. A., Christianson, T. A., Peters, S. T., Ostroski, M. L., Hoatlin, M. E., Zigler, A. J., Heinrich, M. C., Rathbun, R. K., Keeble, W., Faulkner, G. R. & Bagby, J., Feb 19 1998, In : Experimental hematology. 26, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Origin and rapid evolution of a novel murine erythroleukemia virus of the spleen focus-forming virus family

Hoatlin, M. E., Gomez-Lucia, E., Lilly, F., Beckstead, J. H. & Kabat, D., May 1998, In : Journal of virology. 72, 5, p. 3602-3609 8 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

The Fanconi anemia group C gene product is located in both the nucleus and cytoplasm of human cells

Hoatlin, M. E., Christianson, T. A., Keeble, W. W., Hammond, A. T., Zhi, Y., Heinrich, M. C., Tower, P. A. & Bagby, G. C., Feb 15 1998, In : Blood. 91, 4, p. 1418-1425 8 p.

Research output: Contribution to journalArticle

63 Scopus citations
1996

Retroviral transfer of the recombinant human erythropoietin receptor gene into single hematopoietic stem/progenitor cells from human cord blood increases the number of erythropoietin-dependent erythroid colonies

Lu, L., Ge, Y., Li, Z. H., Keeble, W., Kabat, D., Bagby, G. C., Broxmeyer, H. E. & Hoatlin, M. E., Jan 15 1996, In : Blood. 87, 2, p. 525-534 10 p.

Research output: Contribution to journalArticle

Open Access
20 Scopus citations
1995

Deletions in one domain of the Friend virus-encoded membrane glycoprotein overcome host range restrictions for erythroleukemia

Hoatlin, M. E., Ferro, F. E., Geib, R. W., Fox, M. T., Kozak, S. L. & Kabat, D., Feb 1995, In : Journal of virology. 69, 2, p. 856-863 8 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations