Maureen Hoatlin

Associate Professor

  • 5016 Citations
  • 35 h-Index
1985 …2013
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Research Output 1985 2013

  • 5016 Citations
  • 35 h-Index
  • 63 Article
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Article
2013
101 Citations (Scopus)

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

Shen, H., Fridley, B. L., Song, H., Lawrenson, K., Cunningham, J. M., Ramus, S. J., Cicek, M. S., Tyrer, J., Stram, D., Larson, M. C., Köbel, M., Ziogas, A., Zheng, W., Yang, H. P., Wu, A. H., Wozniak, E. L., Ling Woo, Y., Winterhoff, B., Wik, E., Whittemore, A. S. & 148 others, Wentzensen, N., Palmieri Weber, R., Vitonis, A. F., Vincent, D., Vierkant, R. A., Vergote, I., Van Den Berg, D., Van Altena, A. M., Tworoger, S. S., Thompson, P. J., Tessier, D. C., Terry, K. L., Teo, S. H., Templeman, C., Stram, D. O., Southey, M. C., Sieh, W., Siddiqui, N., Shvetsov, Y. B., Shu, X. O., Shridhar, V., Wang-Gohrke, S., Severi, G., Schwaab, I., Salvesen, H. B., Rzepecka, I. K., Runnebaum, I. B., Anne Rossing, M., Rodriguez-Rodriguez, L., Risch, H. A., Renner, S. P., Poole, E. M., Pike, M. C., Phelan, C. M., Pelttari, L. M., Pejovic, T., Paul, J., Orlow, I., Zawiah Omar, S., Olson, S. H., Odunsi, K., Nickels, S., Nevanlinna, H., Ness, R. B., Narod, S. A., Nakanishi, T., Moysich, K. B., Monteiro, A. N. A., Moes-Sosnowska, J., Modugno, F., Menon, U., McLaughlin, J. R., McGuire, V., Matsuo, K., Mat Adenan, N. A., Massuger, L. F. A. G., Lurie, G., Lundvall, L., Lubiński, J., Lissowska, J., Levine, D. A., Leminen, A., Lee, A. W., Le, N. D., Lambrechts, S., Lambrechts, D., Kupryjanczyk, J., Krakstad, C., Konecny, G. E., Krüger Kjaer, S., Kiemeney, L. A., Kelemen, L. E., Keeney, G. L., Karlan, B. Y., Karevan, R., Kalli, K. R., Kajiyama, H., Ji, B. T., Jensen, A., Jakubowska, A., Iversen, E., Hosono, S., Høgdall, C. K., Høgdall, E., Hoatlin, M., Hillemanns, P., Heitz, F., Hein, R., Harter, P., Halle, M. K., Hall, P., Gronwald, J., Gore, M., Goodman, M. T., Giles, G. G., Gentry-Maharaj, A., Garcia-Closas, M., Flanagan, J. M., Fasching, P. A., Ekici, A. B., Edwards, R., Eccles, D., Easton, D. F., Dürst, M., Du Bois, A., Dörk, T., Doherty, J. A., Despierre, E., Dansonka-Mieszkowska, A., Cybulski, C., Cramer, D. W., Cook, L. S., Chen, X., Charbonneau, B., Chang-Claude, J., Campbell, I., Butzow, R., Bunker, C. H., Brueggmann, D., Brown, R., Brooks-Wilson, A., Brinton, L. A., Bogdanova, N., Block, M. S., Benjamin, E., Beesley, J., Beckmann, M. W., Bandera, E. V., Baglietto, L., Bacot, F., Armasu, S. M., Antonenkova, N., Anton-Culver, H., Aben, K. K., Liang, D., Wu, X., Lu, K., Hildebrandt, M. A. T., Schildkraut, J. M., Sellers, T. A., Huntsman, D., Berchuck, A., Chenevix-Trench, G., Gayther, S. A., Pharoah, P. D. P., Laird, P. W., Goode, E. L. & Leigh Pearce, C., 2013, In : Nature Communications. 4, 1628.

Research output: Contribution to journalArticle

Epigenomics
genes
Ovarian Neoplasms
Genes
cancer
218 Citations (Scopus)

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

Pharoah, P. D. P., Tsai, Y. Y., Ramus, S. J., Phelan, C. M., Goode, E. L., Lawrenson, K., Buckley, M., Fridley, B. L., Tyrer, J. P., Shen, H., Weber, R., Karevan, R., Larson, M. C., Song, H., Tessier, D. C., Bacot, F., Vincent, D., Cunningham, J. M., Dennis, J., Dicks, E. & 148 others, Aben, K. K., Anton-Culver, H., Antonenkova, N., Armasu, S. M., Baglietto, L., Bandera, E. V., Beckmann, M. W., Birrer, M. J., Bloom, G., Bogdanova, N., Brenton, J. D., Brinton, L. A., Brooks-Wilson, A., Brown, R., Butzow, R., Campbell, I., Carney, M. E., Carvalho, R. S., Chang-Claude, J., Chen, Y. A., Chen, Z., Chow, W. H., Cicek, M. S., Coetzee, G., Cook, L. S., Cramer, D. W., Cybulski, C., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J. A., Dörk, T., Du Bois, A., Dürst, M., Eccles, D., Edwards, R., Ekici, A. B., Fasching, P. A., Fenstermacher, D., Flanagan, J., Gao, Y. T., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G., Gjyshi, A., Gore, M., Gronwald, J., Guo, Q., Halle, M. K., Harter, P., Hein, A., Heitz, F., Hillemanns, P., Hoatlin, M., Høgdall, E., Høgdall, C. K., Hosono, S., Jakubowska, A., Jensen, A., Kalli, K. R., Karlan, B. Y., Kelemen, L. E., Kiemeney, L. A., Kjaer, S. K., Konecny, G. E., Krakstad, C., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Le, N. D., Lee, N., Lee, J., Leminen, A., Lim, B. K., Lissowska, J., Lubiński, J., Lundvall, L., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S., Orlow, I., Paul, J., Pejovic, T., Pelttari, L. M., Permuth-Wey, J., Pike, M. C., Poole, E. M., Qu, X., Risch, H. A., Rodriguez-Rodriguez, L., Rossing, M. A., Rudolph, A., Runnebaum, I., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shen, H., Shridhar, V., Shu, X. O., Sieh, W., Southey, M. C., Spellman, P., Tajima, K., Teo, S. H., Terry, K. L., Thompson, P. J., Timorek, A., Tworoger, S. S., Van Altena, A. M., Van Den Berg, D., Vergote, I., Vierkant, R. A., Vitonis, A. F., Wang-Gohrke, S., Wentzensen, N., Whittemore, A. S., Wik, E., Winterhoff, B., Woo, Y. L., Wu, A. H., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Goodman, M. T., Hall, P., Easton, D. F., Pearce, C. L., Berchuck, A., Chenevix-Trench, G., Iversen, E., Monteiro, A. N. A., Gayther, S. A., Schildkraut, J. M. & Sellers, T. A., Apr 2013, In : Nature Genetics. 45, 4, p. 362-370 9 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Ovarian Neoplasms
Meta-Analysis
Genome
Nucleic Acid Regulatory Sequences
70 Citations (Scopus)

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

Permuth-Wey, J., Lawrenson, K., Shen, H. C., Velkova, A., Tyrer, J. P., Chen, Z., Lin, H. Y., Ann Chen, Y., Tsai, Y. Y., Qu, X., Ramus, S. J., Karevan, R., Lee, J., Lee, N., Larson, M. C., Aben, K. K., Anton-Culver, H., Antonenkova, N., Antoniou, A. C., Armasu, S. M. & 158 others, Bacot, F., Baglietto, L., Bandera, E. V., Barnholtz-Sloan, J., Beckmann, M. W., Birrer, M. J., Bloom, G., Bogdanova, N., Brinton, L. A., Brooks-Wilson, A., Brown, R., Butzow, R., Cai, Q., Campbell, I., Chang-Claude, J., Chanock, S., Chenevix-Trench, G., Cheng, J. Q., Cicek, M. S., Coetzee, G. A., Cook, L. S., Couch, F. J., Cramer, D. W., Cunningham, J. M., Dansonka-Mieszkowska, A., Despierre, E., Doherty, J. A., Dörk, T., Du Bois, A., Dürst, M., Easton, D. F., Eccles, D., Edwards, R., Ekici, A. B., Fasching, P. A., Fenstermacher, D. A., Flanagan, J. M., Garcia-Closas, M., Gentry-Maharaj, A., Giles, G. G., Glasspool, R. M., Gonzalez-Bosquet, J., Goodman, M. T., Gore, M., Górski, B., Gronwald, J., Hall, P., Halle, M. K., Harter, P., Heitz, F., Hillemanns, P., Hoatlin, M., Høgdall, C. K., Høgdall, E., Hosono, S., Jakubowska, A., Jensen, A., Jim, H., Kalli, K. R., Karlan, B. Y., Kaye, S. B., Kelemen, L. E., Kiemeney, L. A., Kikkawa, F., Konecny, G. E., Krakstad, C., Krüger Kjaer, S., Kupryjanczyk, J., Lambrechts, D., Lambrechts, S., Lancaster, J. M., Le, N. D., Leminen, A., Levine, D. A., Liang, D., Kiong Lim, B., Lin, J., Lissowska, J., Lu, K. H., Lubiński, J., Lurie, G., Massuger, L. F. A. G., Matsuo, K., McGuire, V., McLaughlin, J. R., Menon, U., Modugno, F., Moysich, K. B., Nakanishi, T., Narod, S. A., Nedergaard, L., Ness, R. B., Nevanlinna, H., Nickels, S., Noushmehr, H., Odunsi, K., Olson, S. H., Orlow, I., Paul, J., Pearce, C. L., Pejovic, T., Pelttari, L. M., Pike, M. C., Poole, E. M., Raska, P., Renner, S. P., Risch, H. A., Rodriguez-Rodriguez, L., Anne Rossing, M., Rudolph, A., Runnebaum, I. B., Rzepecka, I. K., Salvesen, H. B., Schwaab, I., Severi, G., Shridhar, V., Shu, X. O., Shvetsov, Y. B., Sieh, W., Song, H., Southey, M. C., Spiewankiewicz, B., Stram, D., Sutphen, R., Teo, S. H., Terry, K. L., Tessier, D. C., Thompson, P. J., Tworoger, S. S., Van Altena, A. M., Vergote, I., Vierkant, R. A., Vincent, D., Vitonis, A. F., Wang-Gohrke, S., Palmieri Weber, R., Wentzensen, N., Whittemore, A. S., Wik, E., Wilkens, L. R., Winterhoff, B., Ling Woo, Y., Wu, A. H., Xiang, Y. B., Yang, H. P., Zheng, W., Ziogas, A., Zulkifli, F., Phelan, C. M., Iversen, E., Schildkraut, J. M., Berchuck, A., Fridley, B. L., Goode, E. L., Pharoah, P. D. P., Monteiro, A. N. A., Sellers, T. A. & Gayther, S. A., 2013, In : Nature Communications. 4, 1627.

Research output: Contribution to journalArticle

loci
Polymorphism
Ovarian Neoplasms
cancer
MicroRNAs
333 Citations (Scopus)

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

Bojesen, S. E., Pooley, K. A., Johnatty, S. E., Beesley, J., Michailidou, K., Tyrer, J. P., Edwards, S. L., Pickett, H. A., Shen, H. C., Smart, C. E., Hillman, K. M., Mai, P. L., Lawrenson, K., Stutz, M. D., Lu, Y., Karevan, R., Woods, N., Johnston, R. L., French, J. D., Chen, X. & 417 others, Weischer, M., Nielsen, S. F., Maranian, M. J., Ghoussaini, M., Ahmed, S., Baynes, C., Bolla, M. K., Wang, Q., Dennis, J., McGuffog, L., Barrowdale, D., Lee, A., Healey, S., Lush, M., Tessier, D. C., Vincent, D., Bacot, F., Vergote, I., Lambrechts, S., Despierre, E., Risch, H. A., González-Neira, A., Rossing, M. A., Pita, G., Doherty, J. A., Álvarez, N., Larson, M. C., Fridley, B. L., Schoof, N., Chang-Claude, J., Cicek, M. S., Peto, J., Kalli, K. R., Broeks, A., Armasu, S. M., Schmidt, M. K., Braaf, L. M., Winterhoff, B., Nevanlinna, H., Konecny, G. E., Lambrechts, D., Rogmann, L., Guénel, P., Teoman, A., Milne, R. L., Garcia, J. J., Cox, A., Shridhar, V., Burwinkel, B., Marme, F., Hein, R., Sawyer, E. J., Haiman, C. A., Wang-Gohrke, S., Andrulis, I. L., Moysich, K. B., Hopper, J. L., Odunsi, K., Lindblom, A., Giles, G. G., Brenner, H., Simard, J., Lurie, G., Fasching, P. A., Carney, M. E., Radice, P., Wilkens, L. R., Swerdlow, A., Goodman, M. T., Brauch, H., Garcia-Closas, M., Hillemanns, P., Winqvist, R., Dürst, M., Devilee, P., Runnebaum, I., Jakubowska, A., Lubinski, J., Mannermaa, A., Butzow, R., Bogdanova, N. V., Dörk, T., Pelttari, L. M., Zheng, W., Leminen, A., Anton-Culver, H., Bunker, C. H., Kristensen, V., Ness, R. B., Muir, K., Edwards, R., Meindl, A., Heitz, F., Matsuo, K., Du Bois, A., Wu, A. H., Harter, P., Teo, S. H., Schwaab, I., Shu, X. O., Blot, W., Hosono, S., Kang, D., Nakanishi, T., Hartman, M., Yatabe, Y., Hamann, U., Karlan, B. Y., Sangrajrang, S., Kjaer, S. K., Gaborieau, V., Jensen, A., Eccles, D., Høgdall, E., Shen, C. Y., Brown, J., Woo, Y. L., Shah, M., Azmi, M. A. N., Luben, R., Omar, S. Z., Czene, K., Vierkant, R. A., Nordestgaard, B. G., Flyger, H., Vachon, C., Olson, J. E., Wang, X., Levine, D. A., Rudolph, A., Weber, R. P., Flesch-Janys, D., Iversen, E., Nickels, S., Schildkraut, J. M., Silva, I. D. S., Cramer, D. W., Gibson, L., Terry, K. L., Fletcher, O., Vitonis, A. F., Van Der Schoot, C. E., Poole, E. M., Hogervorst, F. B. L., Tworoger, S. S., Liu, J., Bandera, E. V., Li, J., Olson, S. H., Humphreys, K., Orlow, I., Blomqvist, C., Rodriguez-Rodriguez, L., Aittomäki, K., Salvesen, H. B., Muranen, T. A., Wik, E., Brouwers, B., Krakstad, C., Wauters, E., Halle, M. K., Wildiers, H., Kiemeney, L. A., Mulot, C., Aben, K. K., Laurent-Puig, P., Altena, A. M., Truong, T., Massuger, L. F. A. G., Benitez, J., Pejovic, T., Perez, J. I. A., Hoatlin, M., Zamora, M. P., Cook, L. S., Balasubramanian, S. P., Kelemen, L. E., Schneeweiss, A., Le, N. D., Sohn, C., Brooks-Wilson, A., Tomlinson, I., Kerin, M. J., Miller, N., Cybulski, C., Henderson, B. E., Menkiszak, J., Schumacher, F., Wentzensen, N., Le Marchand, L., Yang, H. P., Mulligan, A. M., Glendon, G., Engelholm, S. A., Knight, J. A., Høgdall, C. K., Apicella, C., Gore, M., Tsimiklis, H., Song, H., Southey, M. C., Jager, A., Den Ouweland, A. M. W., Brown, R., Martens, J. W. M., Flanagan, J. M., Kriege, M., Paul, J., Margolin, S., Siddiqui, N., Severi, G., Whittemore, A. S., Baglietto, L., McGuire, V., Stegmaier, C., Sieh, W., Müller, H., Arndt, V., Labrèche, F., Gao, Y. T., Goldberg, M. S., Yang, G., Dumont, M., McLaughlin, J. R., Hartmann, A., Ekici, A. B., Beckmann, M. W., Phelan, C. M., Lux, M. P., Permuth-Wey, J., Peissel, B., Sellers, T. A., Ficarazzi, F., Barile, M., Ziogas, A., Ashworth, A., Gentry-Maharaj, A., Jones, M., Ramus, S. J., Orr, N., Menon, U., Pearce, C. L., Brüning, T., Pike, M. C., Ko, Y. D., Lissowska, J., Figueroa, J., Kupryjanczyk, J., Chanock, S. J., Dansonka-Mieszkowska, A., Jukkola-Vuorinen, A., Rzepecka, I. K., Pylkäs, K., Bidzinski, M., Kauppila, S., Hollestelle, A., Seynaeve, C., Tollenaar, R. A. E. M., Durda, K., Jaworska, K., Hartikainen, J. M., Kosma, V. M., Kataja, V., Antonenkova, N. N., Long, J., Shrubsole, M., Deming-Halverson, S., Lophatananon, A., Siriwanarangsan, P., Stewart-Brown, S., Ditsch, N., Lichtner, P., Schmutzler, R. K., Ito, H., Iwata, H., Tajima, K., Tseng, C. C., Stram, D. O., Van Den Berg, D., Yip, C. H., Ikram, M. K., Teh, Y. C., Cai, H., Lu, W., Signorello, L. B., Cai, Q., Noh, D. Y., Yoo, K. Y., Miao, H., Iau, P. T. C., Teo, Y. Y., McKay, J., Shapiro, C., Ademuyiwa, F., Fountzilas, G., Hsiung, C. N., Yu, J. C., Hou, M. F., Healey, C. S., Luccarini, C., Peock, S., Stoppa-Lyonnet, D., Peterlongo, P., Rebbeck, T. R., Piedmonte, M., Singer, C. F., Friedman, E., Thomassen, M., Offit, K., Hansen, T. V. O., Neuhausen, S. L., Szabo, C. I., Blanco, I., Garber, J., Narod, S. A., Weitzel, J. N., Montagna, M., Olah, E., Godwin, A. K., Yannoukakos, D., Goldgar, D. E., Caldes, T., Imyanitov, E. N., Tihomirova, L., Arun, B. K., Campbell, I., Mensenkamp, A. R., Van Asperen, C. J., Van Roozendaal, K. E. P., Meijers-Heijboer, H., Collée, J. M., Oosterwijk, J. C., Hooning, M. J., Rookus, M. A., Van Der Luijt, R. B., Os, T. A. M., Evans, D. G., Frost, D., Fineberg, E., Barwell, J., Walker, L., Kennedy, M. J., Platte, R., Davidson, R., Ellis, S. D., Cole, T., Bressac-De Paillerets, B., Buecher, B., Damiola, F., Faivre, L., Frenay, M., Sinilnikova, O. M., Caron, O., Giraud, S., Mazoyer, S., Bonadona, V., Caux-Moncoutier, V., Toloczko-Grabarek, A., Gronwald, J., Byrski, T., Spurdle, A. B., Bonanni, B., Zaffaroni, D., Giannini, G., Bernard, L., Dolcetti, R., Manoukian, S., Arnold, N., Engel, C., Deissler, H., Rhiem, K., Niederacher, D., Plendl, H., Sutter, C., Wappenschmidt, B., Borg, Å., Melin, B., Rantala, J., Soller, M., Nathanson, K. L., Domchek, S. M., Rodriguez, G. C., Salani, R., Kaulich, D. G., Tea, M. K., Paluch, S. S., Laitman, Y., Skytte, A. B., Kruse, T. A., Jensen, U. B., Robson, M., Gerdes, A. M., Ejlertsen, B., Foretova, L., Savage, S. A., Lester, J., Soucy, P., Kuchenbaecker, K. B., Olswold, C., Cunningham, J. M., Slager, S., Pankratz, V. S., Dicks, E., Lakhani, S. R., Couch, F. J., Hall, P., Monteiro, A. N. A., Gayther, S. A., Pharoah, P. D. P., Reddel, R. R., Goode, E. L., Greene, M. H., Easton, D. F., Berchuck, A., Antoniou, A. C., Chenevix-Trench, G. & Dunning, A. M., Apr 2013, In : Nature Genetics. 45, 4, p. 371-384 14 p.

Research output: Contribution to journalArticle

Telomere
Ovarian Neoplasms
Single Nucleotide Polymorphism
Breast Neoplasms
Alleles
2012
48 Citations (Scopus)

A Ubiquitin-Binding Protein, FAAP20, Links RNF8-Mediated Ubiquitination to the Fanconi Anemia DNA Repair Network

Yan, Z., Guo, R., Paramasivam, M., Shen, W., Ling, C., Fox, D., Wang, Y., Oostra, A. B., Kuehl, J., Lee, D. Y., Takata, M., Hoatlin, M., Schindler, D., Joenje, H., de Winter, J. P., Li, L., Seidman, M. M. & Wang, W., Jul 13 2012, In : Molecular Cell. 47, 1, p. 61-75 15 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Ubiquitination
Ubiquitin
DNA Repair
Carrier Proteins
36 Citations (Scopus)

BRCAness profile of sporadic ovarian cancer predicts disease recurrence

Wysham, W. Z., Mhawech-Fauceglia, P., Li, H., Hays, L., Syriac, S., Skrepnik, T., Wright, J., Pande, N., Hoatlin, M. & Pejovic, T., Jan 11 2012, In : PLoS One. 7, 1, e30042.

Research output: Contribution to journalArticle

ovarian neoplasms
relapse
homologous recombination
Ovarian Neoplasms
Homologous Recombination
11 Citations (Scopus)

Targeting the fanconi anemia pathway to identify tailored anticancer therapeutics

Jenkins, C., Kan, J. & Hoatlin, M., 2012, In : Anemia. 2012, 481583.

Research output: Contribution to journalArticle

Fanconi Anemia
Neoplasms
Therapeutics
Recombinational DNA Repair
Multiprotein Complexes
2011
7 Citations (Scopus)

Evidence for complete epistasis of null mutations in murine Fanconi anemia genes Fanca and Fancg

Van de Vrugt, H. J., Koomen, M., Bakker, S., Berns, M. A. D., Cheng, N. C., van der Valk, M. A., de Vries, Y., Rooimans, M. A., Oostra, A. B., Hoatlin, M., te Riele, H., Joenje, H. & Arwert, F., Dec 10 2011, In : DNA Repair. 10, 12, p. 1252-1261 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Genes
Ligases
Ubiquitin
Mutation
2010
140 Citations (Scopus)

A Histone-Fold Complex and FANCM Form a Conserved DNA-Remodeling Complex to Maintain Genome Stability

Yan, Z., Delannoy, M., Ling, C., Daee, D., Osman, F., Muniandy, P. A., Shen, X., Oostra, A. B., Du, H., Steltenpool, J., Lin, T., Schuster, B., Décaillet, C., Stasiak, A., Stasiak, A. Z., Stone, S., Hoatlin, M., Schindler, D., Woodcock, C. L., Joenje, H. & 8 others, Sen, R., de Winter, J. P., Li, L., Seidman, M. M., Whitby, M. C., Myung, K., Constantinou, A. & Wang, W., Mar 26 2010, In : Molecular Cell. 37, 6, p. 865-878 14 p.

Research output: Contribution to journalArticle

Genomic Instability
Histones
DNA
DNA Replication
DNA Damage

A new FAN of the stalled replication fork

Hoatlin, M., Nov 1 2010, In : Cell Cycle. 9, 21, p. 4261-4262 2 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Structure-specific recognition protein 1 facilitates microtubule growth and bundling required for mitosis

Zeng, S. X., Li, Y., Jin, Y., Zhang, Q., Keller, D. M., McQuaw, C. M., Barklis, E., Stone, S., Hoatlin, M., Zhao, Y. & Lu, H., Feb 2010, In : Molecular and Cellular Biology. 30, 4, p. 935-947 13 p.

Research output: Contribution to journalArticle

Mitosis
Microtubules
Growth
Proteins
Chromosomes
2009
28 Citations (Scopus)

A novel cell-free screen identifies a potent inhibitor of the fanconi anemia pathway

Lanclais, I., Sobeck, A., Stone, S., LaChapelle, A. & Hoatlin, M., Feb 15 2009, In : International Journal of Cancer. 124, 4, p. 783-792 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Naphthoquinones
Cisplatin
Xenopus
DNA Damage
30 Citations (Scopus)

Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

Landais, I., Hiddingh, S., McCarroll, M., Yang, C., Sun, A., Turker, M., Snyder, J. P. & Hoatlin, M., Dec 31 2009, In : Molecular Cancer. 8, 133.

Research output: Contribution to journalArticle

Fanconi Anemia
Curcumin
Ataxia
DNA Repair
DNA Damage
28 Citations (Scopus)

The Fanconi anemia protein FANCM is controlled by FANCD2 and the ATR/ATM pathways

Sobeck, A., Stone, S., Landais, I., de Graaf, B. & Hoatlin, M., Sep 18 2009, In : Journal of Biological Chemistry. 284, 38, p. 25560-25568 9 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Automatic teller machines
DNA Damage
Fanconi Anemia
DNA
13 Citations (Scopus)

Transcriptional activation by the Mixl1 homeodomain protein in differentiating mouse embryonic stem cells

Zhang, H., Fraser, S. T., Papazoglu, C., Hoatlin, M. & Baron, M. H., Dec 2009, In : Stem Cells. 27, 12, p. 2884-2895 12 p.

Research output: Contribution to journalArticle

Homeodomain Proteins
Mesoderm
Embryonic Stem Cells
Base Pairing
Transcriptional Activation
2008
66 Citations (Scopus)

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

Wilson, J. B., Yamamoto, K., Marriott, A. S., Hussain, S., Sung, P., Hoatlin, M., Mathew, C. G., Takata, M., Thompson, L. H., Kupfer, G. M. & Jones, N. J., Jun 12 2008, In : Oncogene. 27, 26, p. 3641-3652 12 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Recombinational DNA Repair
Fanconi Anemia Complementation Group G Protein
Serine
Fanconi Anemia Complementation Group Proteins
51 Citations (Scopus)

Fanconi anemia proteins stabilize replication forks

Wang, L. C., Stone, S., Hoatlin, M. & Gautier, J., Dec 1 2008, In : DNA Repair. 7, 12, p. 1973-1981 9 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
DNA Replication
DNA
DNA Repair
125 Citations (Scopus)

RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability

Xu, D., Guo, R., Sobeck, A., Bachrati, C. Z., Yang, J., Enomoto, T., Brown, G. W., Hoatlin, M., Hickson, I. D. & Wang, W., Oct 15 2008, In : Genes and Development. 22, 20, p. 2843-2855 13 p.

Research output: Contribution to journalArticle

Sister Chromatid Exchange
Genomic Instability
Bloom Syndrome
Oligonucleotides
Proteins
2007
29 Citations (Scopus)

DNA structure-induced recruitment and activation of the Fanconi anemia pathway protein FANCD2

Sobeck, A., Stone, S. & Hoatlin, M., Jun 2007, In : Molecular and Cellular Biology. 27, 12, p. 4283-4292 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
DNA
Xenopus laevis
DNA Replication
107 Citations (Scopus)

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

Ling, C., Ishiai, M., Ali, A. M., Medhurst, A. L., Neveling, K., Kalb, R., Yan, Z., Xue, Y., Oostra, A. B., Auerbach, A. D., Hoatlin, M., Schindler, D., Joenje, H., De Winter, J. P., Takata, M., Meetei, A. R. & Wang, W., Apr 18 2007, In : EMBO Journal. 26, 8, p. 2104-2114 11 p.

Research output: Contribution to journalArticle

Fanconi Anemia
DNA Damage
Chemical activation
DNA
Fanconi Anemia Complementation Group Proteins
7 Citations (Scopus)

Identification, developmental expression and regulation of the Xenopus ortholog of human FANCG/XRCC9

Stone, S., Sobeck, A., van Kogelenberg, M., de Graaf, B., Joenje, H., Christian, J. & Hoatlin, M., Jul 2007, In : Genes to Cells. 12, 7, p. 841-851 11 p.

Research output: Contribution to journalArticle

Xenopus
Fanconi Anemia
Protein Isoforms
Leucine Zippers
Bone Neoplasms
2006
80 Citations (Scopus)

Fanconi anemia proteins are required to prevent accumulation of replication-associated DNA double-strand breaks

Sobeck, A., Stone, S., Costanzo, V., De Graaf, B., Reuter, T., De Winter, J., Wallisch, M., Akkari, Y., Olson, S., Wang, W., Joenje, H., Christian, J. L., Lupardus, P. J., Cimprich, K. A., Gautier, J. & Hoatlin, M., Jan 2006, In : Molecular and Cellular Biology. 26, 2, p. 425-437 13 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Double-Stranded DNA Breaks
Mitomycin
Chromatin
DNA Breaks
19 Citations (Scopus)

The nuclear accumulation of the Fanconi anemia protein FANCE depends on FANCC

Léveillé, F., Ferrer, M., Medhurst, A. L., Laghmani, E. H., Rooimans, M. A., Bier, P., Steltenpool, J., Titus, T. A., Postlethwait, J. H., Hoatlin, M., Joenje, H. & de Winter, J. P., May 10 2006, In : DNA Repair. 5, 5, p. 556-565 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
Nuclear Export Signals
Nuclear Localization Signals
Repair
2005
329 Citations (Scopus)

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M

Meetei, A. R., Medhurst, A. L., Ling, C., Xue, Y., Singh, T. R., Bier, P., Steltenpool, J., Stone, S., Dokal, I., Mathew, C. G., Hoatlin, M., Joenje, H., De Winter, J. P. & Wang, W., Sep 2005, In : Nature Genetics. 37, 9, p. 958-963 6 p.

Research output: Contribution to journalArticle

Archaeal DNA
Fanconi Anemia
DNA Repair
Proteins
DNA Damage
136 Citations (Scopus)

BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

Yin, J., Sobeck, A., Xu, C., Meetei, A. R., Hoatlin, M., Li, L. & Wang, W., Apr 6 2005, In : EMBO Journal. 24, 7, p. 1465-1476 12 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Genes
Bloom Syndrome
Genome
Dwarfism
2004
190 Citations (Scopus)

Heterogeneity in Fanconi anemia: Evidence for 2 new genetic subtypes

Levitus, M., Rooimans, M. A., Steltenpool, J., Cool, N. F. C., Oostra, A. B., Mathew, C. G., Hoatlin, M., Waisfisz, Q., Arwert, F., De Winter, J. P. & Joenje, H., Apr 1 2004, In : Blood. 103, 7, p. 2498-2503 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Genes
Cells
Fanconi Anemia Complementation Group D2 Protein
Defects
52 Citations (Scopus)

The Fanconi anemia gene product FANCF is a flexible adaptor protein

Léveillé, F., Blom, E., Medhurst, A. L., Bier, P., Laghmani, E. H., Johnson, M., Rooimans, M. A., Sobeck, A., Waisfisz, Q., Arwert, F., Patel, K. J., Hoatlin, M., Joenje, H. & De Winter, J. P., Sep 17 2004, In : Journal of Biological Chemistry. 279, 38, p. 39421-39430 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
Fanconi Anemia Complementation Group F Protein
Genes
Amino Acids
223 Citations (Scopus)

X-linked inheritance of Fanconi anemia complementation group B

Meetei, A. R., Levitus, M., Xue, Y., Medhurst, A. L., Zwaan, M., Ling, C., Rooimans, M. A., Bier, P., Hoatlin, M., Pals, G., De Winter, J. P., Wang, W. & Joenje, H., Nov 2004, In : Nature Genetics. 36, 11, p. 1219-1224 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia
X-Linked Genes
BRCA2 Gene
X Chromosome Inactivation
Chromosomal Instability
2003
273 Citations (Scopus)

A multiprotein nuclear complex connects fanconi anemia and bloom syndrome

Meetei, A. R., Sechi, S., Wallisch, M., Yang, D., Young, M. K., Joenje, H., Hoatlin, M. & Wang, W., May 2003, In : Molecular and Cellular Biology. 23, 10, p. 3417-3426 10 p.

Research output: Contribution to journalArticle

Bloom Syndrome
Fanconi Syndrome
Fanconi Anemia
Multiprotein Complexes
Fanconi Anemia Complementation Group Proteins
433 Citations (Scopus)

A novel ubiquitin ligase is deficient in Fanconi anemia

Meetei, A. R., De Winter, J. P., Medhurst, A. L., Wallisch, M., Waisfisz, Q., Van de Vrugt, H. J., Oostra, A. B., Yan, Z., Ling, C., Bishop, C. E., Hoatlin, M., Joenje, H. & Wang, W., Oct 1 2003, In : Nature Genetics. 35, 2, p. 165-170 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Ligases
Ubiquitin
Fanconi Anemia Complementation Group Proteins
Bone Neoplasms
21 Citations (Scopus)

FANCD2 protein is expressed in proliferating cells of human tissues that are cancer-prone in Fanconi anaemia

Hölzel, M., van Diest, P. J., Bier, P., Wallisch, M., Hoatlin, M., Joenje, H. & de Winter, J. P., Oct 1 2003, In : Journal of Pathology. 201, 2, p. 198-203 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group D2 Protein
Fanconi Anemia
Neoplasms
Fanconi Anemia Complementation Group Proteins
Epithelium
41 Citations (Scopus)

Genetic reversion in an acute myelogenous leukemia cell line from a Fanconi anemia patient with biallelic mutations in BRCA2

Ikeda, H., Matsushita, M., Waisfisz, Q., Kinoshita, A., Oostra, A. B., Nieuwint, A. W. M., De Winter, J. P., Hoatlin, M., Kawai, Y., Sasaki, M. S., D'Andrea, A. D., Kawakami, Y. & Joenje, H., May 15 2003, In : Cancer Research. 63, 10, p. 2688-2694 7 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Acute Myeloid Leukemia
Cell Line
Mutation
Myeloid Cells
45 Citations (Scopus)

Yeast two-hybrid screens imply involvement of fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport

Reuter, T. Y., Medhurst, A. L., Waisfisz, Q., Zhi, Y., Herterich, S., Hoehn, H., Gross, H. J., Joenje, H., Hoatlin, M., Mathew, C. G. & Huber, P. A. J., Oct 1 2003, In : Experimental Cell Research. 289, 2, p. 211-221 11 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
Yeasts
Genes
Proteins
2002
16 Citations (Scopus)

Characterization, expression and complex formation of the murine Fanconi anaemia gene product Fancg

Van De Vrugt, H. J., Koomen, M., Berns, M. A. D., De Vries, Y., Rooimans, M. A., Van Der Weel, L., Blom, E., De Groot, J., Schepers, R. J., Stone, S., Hoatlin, M., Cheng, N. C., Joenje, H. & Arwert, F., 2002, In : Genes to Cells. 7, 3, p. 333-342 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Genes
Proteins
Chromosome Disorders
Gastrin-Secreting Cells
128 Citations (Scopus)

FANCE: The link between Fanconi anaemia complex assembly and activity

Pace, P., Johnson, M., Tan, W. M., Mosedale, G., Sng, C., Hoatlin, M., De Winter, J., Joenje, H., Gergely, F. & Patel, K. J., Jul 1 2002, In : EMBO Journal. 21, 13, p. 3414-3423 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Chromosome Breakage
Fanconi Anemia Complementation Group E Protein
Chromosomes
Fanconi Anemia Complementation Group D2 Protein
22 Citations (Scopus)

Fanconi anemia protein complex is a novel target of the IKK signalsome

Otsuki, T., Young, D. B., Sasaki, D. T., Pando, M. P., Li, J., Manning, A., Hoekstra, M., Hoatlin, M., Mercurio, F. & Liu, J. M., 2002, In : Journal of Cellular Biochemistry. 86, 4, p. 613-623 11 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
Phosphotransferases
Cells
Inborn Genetic Diseases
25 Citations (Scopus)

The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific

Dai, M., Chevallier, N., Stone, S., Heinrich, M., McConnell, M., Reuter, T., Broxmeyer, H. E., Licht, J. D., Lu, L. & Hoatlin, M., Jul 19 2002, In : Journal of Biological Chemistry. 277, 29, p. 26327-26334 8 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Zinc Fingers
Zinc
Cell Cycle
Cells
2001
4 Citations (Scopus)

Foci on Fanconi

Hoatlin, M. & Reuter, T., 2001, In : Trends in Molecular Medicine. 7, 6, p. 237-239 3 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
Genomic Instability
DNA Damage
Yeasts
2000
35 Citations (Scopus)

Aberrant Fanconi anaemia protein profiles in acute myeloid leukaemia cells

Xie, Y., De Winter, J. P., Waisfisz, Q., Nieuwint, A. W. M., Scheper, R. J., Arwert, F., Hoatlin, M., Ossenkoppele, G. J., Schuurhuis, G. J. & Joenje, H., 2000, In : British Journal of Haematology. 111, 4, p. 1057-1064 8 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
Myeloid Cells
Acute Myeloid Leukemia
Cell Line
28 Citations (Scopus)

Cloning and characterization of murine fanconi anemia group A gene: Fanca protein is expressed in lymphoid tissues, testis, and ovary

Van De Vrugt, H. J., Cheng, N. C., De Vries, Y., Rooimans, M. A., De Groot, J., Scheper, R. J., Zhi, Y., Hoatlin, M., Joenje, H. & Arwert, F., 2000, In : Mammalian Genome. 11, 4, p. 326-331 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Lymphoid Tissue
Testis
Organism Cloning
Ovary
21 Citations (Scopus)

Posttranscriptional cell cycle-dependent regulation of human FANCC expression

Heinrich, M., Silvey, K. V., Stone, S., Zigler, A. J., Griffith, D. J., Montalto, M., Chai, L., Zhi, Y. & Hoatlin, M., Jun 15 2000, In : Blood. 95, 12, p. 3970-3977 8 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Cell Cycle
Fanconi Anemia Complementation Group Proteins
Cells
Proteasome Endopeptidase Complex
228 Citations (Scopus)

The Fanconi anaemia gene FANCF encodes a novel protein with homology to ROM

De Winter, J. P., Rooimans, M. A., Van Der Weel, L., Van Berkel, C. G. M., Alon, N., Bosnoyan-Collins, L., De Groot, J., Zhi, Y., Waisfisz, Q., Pronk, J. C., Arwert, F., Mathew, C. G., Scheper, R. J., Hoatlin, M., Buchwald, M. & Joenje, H., 2000, In : Nature Genetics. 24, 1, p. 15-16 2 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group F Protein
Molecular Sequence Data
Fanconi Anemia
Amino Acid Sequence Homology
RNA-Binding Proteins
170 Citations (Scopus)

The Fanconi anemia protein FANCF forms a nuclear complex with FANCA, FANCC and FANCG

De Winter, J. P., Van Der Weel, L., De Groot, J., Stone, S., Waisfisz, Q., Arwert, F., Scheper, R. J., Kruyt, F. A. E., Hoatlin, M. & Joenje, H., Nov 1 2000, In : Human Molecular Genetics. 9, 18, p. 2665-2674 10 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
Amino Acid Sequence Homology
Chromosome Breakage
Chromosomal Instability
1999
106 Citations (Scopus)

A novel BTB/POZ transcriptional repressor protein interacts with the Fanconi anemia group C protein and PLZF

Hoatlin, M., Yu, Z., Ball, H., Silvey, K., Melnick, A., Stone, S., Arai, S., Hawe, N., Owen, G., Zelent, A. & Licht, J. D., Dec 1 1999, In : Blood. 94, 11, p. 3737-3747 11 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group C Protein
Repressor Proteins
Fanconi Anemia
Zinc Fingers
Zinc
122 Citations (Scopus)

A physical complex of the Fanconi anemia proteins FANCG/XRCC9 and FANCA

Waisfisz, Q., De Winter, J. P., Kruyt, F. A. E., De Groot, J., Van Der Weel, L., Dijkmans, L. M., Zhi, Y., Arwert, F., Scheper, R. J., Youssoufian, H., Hoatlin, M. & Joenje, H., Aug 31 1999, In : Proceedings of the National Academy of Sciences of the United States of America. 96, 18, p. 10320-10325 6 p.

Research output: Contribution to journalArticle

Fanconi Anemia Complementation Group Proteins
Fanconi Anemia
Fanconi Anemia Complementation Group A Protein
Phenotype
Chromosomal Instability
149 Citations (Scopus)

Spontaneous functional correction of homozygous Fanconi anaemia alleles reveals novel mechanistic basis for reverse mosaicism

Waisfisz, Q., Morgan, N. V., Savino, M., De Winter, J. P., Van Berkel, C. G. M., Hoatlin, M., Ianzano, L., Gibson, R. A., Arwert, F., Savoia, A., Mathew, C. G., Pronk, J. C. & Joenje, H., Aug 1999, In : Nature Genetics. 22, 4, p. 379-383 5 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Frameshift Mutation
Mosaicism
Missense Mutation
Alleles
1998
5 Citations (Scopus)

An array of novel murine spleen focus-forming viruses that activate the erythropoietin receptor

Gomez-Lucia, E., Yu, Z., Nabavi, M., Zhang, W., Kabat, D. & Hoatlin, M., May 1998, In : Journal of Virology. 72, 5, p. 3742-3750 9 p.

Research output: Contribution to journalArticle

Spleen Focus-Forming Viruses
Erythropoietin Receptors
env Genes
erythropoietin
spleen
61 Citations (Scopus)

DNA cross-linker-induced G2/M arrest in group C Fanconi anemia lymphoblasts reflects normal checkpoint function

Heinrich, M., Hoatlin, M., Zigler, A. J., Silvey, K. V., Bakke, A. C., Keeble, W. W., Zhi, Y., Reifsteck, C. A., Grompe, M., Brown, M. G., Magenis, R. E., Olson, S. & Bagby, G. C., Jan 1 1998, In : Blood. 91, 1, p. 275-287 13 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Cells
DNA
Cell Cycle
Mitomycin
10 Citations (Scopus)

Expression of the Fanconi anemia group C gene in hematopoietic cells is not influenced by oxidative stress, cross-linking agents, radiation, heat, or mitotic inhibitory factors

Tower, P. A., Christianson, T. A., Peters, S. T., Ostroski, M. L., Hoatlin, M., Zigler, A. J., Heinrich, M., Rathbun, R. K., Keeble, W., Faulkner, G. R. & Bagby G.C., J., 1998, In : Experimental Hematology. 26, 1, p. 19-26 8 p.

Research output: Contribution to journalArticle

Fanconi Anemia
Oxidative Stress
Hot Temperature
Radiation
Messenger RNA
2 Citations (Scopus)

Origin and rapid evolution of a novel murine erythroleukemia virus of the spleen focus-forming virus family

Hoatlin, M., Gomez-Lucia, E., Lilly, F., Beckstead, J. H. & Kabat, D., May 1998, In : Journal of Virology. 72, 5, p. 3602-3609 8 p.

Research output: Contribution to journalArticle

Spleen Focus-Forming Viruses
Leukemia, Erythroblastic, Acute
spleen
Viruses
viruses