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Matthew Whorton

Assistant Scientist

  • 1384 Citations
  • 11 h-Index
20012017
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Research Output 2001 2017

  • 1384 Citations
  • 11 h-Index
  • 14 Article
  • 1 Chapter
  • 1 Comment/debate
38 Citations

Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating

Martin, G. M., Yoshioka, C., Rex, E. A., Fay, J. F., Xie, Q., Whorton, M. R., Chen, J. Z. & Shyng, S. L., Jan 16 2017, In : eLife. 6, e24149

Research output: Contribution to journal › Article

KATP Channels
Glyburide
Adenosine Triphosphate
Hypoglycemic Agents
Conformations

Calcium-activated proteins visualized

Whorton, M., Dec 11 2014, In : Nature. 516, 7530, p. 176-178 3 p.

Research output: Contribution to journal › Comment/debate

Chloride Channels
X Ray Crystallography
Calcium
Proteins
21 Citations

Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system

Wang, W., Whorton, M. R. & MacKinnon, R., 2014, In : eLife. 3, p. e03671

Research output: Contribution to journal › Article

Membrane Lipids
GTP-Binding Proteins
Lipids
Neurons
Pacemakers
117 Citations

X-ray structure of the mammalian GIRK2-βγ G-protein complex

Whorton, M. R. & MacKinnon, R., 2013, In : Nature. 498, 7453, p. 190-197 8 p.

Research output: Contribution to journal › Article

Inwardly Rectifying Potassium Channel
GTP-Binding Proteins
X-Rays
Protein Subunits
G-Protein-Coupled Receptors
215 Citations

Crystal structure of the mammalian GIRK2 K + channel and gating regulation by G proteins, PIP 2, and sodium

Whorton, M. R. & MacKinnon, R., Sep 30 2011, In : Cell. 147, 1, p. 199-208 10 p.

Research output: Contribution to journal › Article

GTP-Binding Proteins
Crystal structure
Sodium
Physiology
Heart Rate