Matthew Ford &ndash; Publications

2019

Chronic ethanol drinking increases during the luteal menstrual cycle phase in rhesus monkeys: implication of progesterone and related neurosteroids

Dozier, B., Stull, C. A., Baker, E. J., Ford, M., Jensen, J. P., Finn, D. D. & Grant, K. K., Jan 1 2019, (Accepted/In press) In : Psychopharmacology.

Research output: Contribution to journal › Article

Luteal Phase

Macaca mulatta

Drinking

Progesterone

Neurotransmitter Agents

1 Citation (Scopus)

Detecting Neurodevelopmental Effects of Early-Gestation Ethanol Exposure: A Nonhuman Primate Model of Ethanol Drinking During Pregnancy

Jimenez, V. A., Wang, X., Newman, N., Walter, N. A. R., Gonzales, S., Lo, J., Ford, M., Cuzon Carlson, V., Grant, K. K. & Kroenke, C. C., Jan 1 2019, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journal › Article

Primates

Drinking

Ethanol

Alcohols

Pregnancy

Genotype Differences in Sensitivity to the Anticonvulsant Effect of the Synthetic Neurosteroid Ganaxolone during Chronic Ethanol Withdrawal

Nipper, M. A., Jensen, J. P., Helms, M. L., Ford, M., Crabbe, J. J., Rossi, D. J. & Finn, D. D., Jan 15 2019, In : Neuroscience. 397, p. 127-137 11 p.

Research output: Contribution to journal › Article

Anticonvulsants

Pregnanolone

Neurotransmitter Agents

Seizures

Ethanol

Modulation of Gpr39, a G-protein coupled receptor associated with alcohol use in non-human primates, curbs ethanol intake in mice

Cuzon Carlson, V., Ford, M., Carlson, T. L., Lomniczi, A., Grant, K. K., Ferguson, B. & Cervera-Juanes, R. P., Jan 1 2019, In : Neuropsychopharmacology.

Research output: Contribution to journal › Article

G-Protein-Coupled Receptors

Primates

Ethanol

Alcohols

Nucleus Accumbens

2018

3 Citations (Scopus)

Cross-Species Translational Findings in the Discriminative Stimulus Effects of Ethanol

Allen, D. C., Ford, M. & Grant, K. K., Jan 1 2018, Current Topics in Behavioral Neurosciences. Springer Verlag, p. 95-111 17 p. (Current Topics in Behavioral Neurosciences; vol. 39).

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Ethanol

Laboratory Animals

Optogenetics

GABA Receptors

Glutamate Receptors

2017

19 Citations (Scopus)

CNS-wide sexually dimorphic induction of the major histocompatibility complex 1 pathway with aging

Mangold, C. A., Masser, D. R., Stanford, D. R., Bixler, G. V., Pisupati, A., Giles, C. B., Wren, J. D., Ford, M., Sonntag, W. E. & Freeman, W. M., 2017, In : Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 72, 1, p. 16-29 14 p.

Research output: Contribution to journal › Article

Major Histocompatibility Complex

Central Nervous System

Neuronal Plasticity

Synapses

Histamine H2 Receptors

6 Citations (Scopus)

Control of chronic excessive alcohol drinking by genetic manipulation of the Edinger-Westphal nucleus urocortin-1 neuropeptide system

Giardino, W. J., Rodriguez, E. D., Smith, M. L., Ford, M., Galili, D., Mitchell, S., Chen, A. & Ryabinin, A., Jan 1 2017, In : Translational Psychiatry. 7, 1, e1021.

Research output: Contribution to journal › Article

Urocortins

Neuropeptides

Alcohol Drinking

Alcohols

Neurons

5 Citations (Scopus)

Ethanol withdrawal-induced dysregulation of neurosteroid levels in plasma, cortex, and hippocampus in genetic animal models of high and low withdrawal

Jensen, J. P., Nipper, M. A., Helms, M. L., Ford, M., Crabbe, J. J., Rossi, D. J. & Finn, D. D., Jun 29 2017, (Accepted/In press) In : Psychopharmacology. p. 1-19 19 p.

Research output: Contribution to journal › Article

Genetic Models

Neurotransmitter Agents

Hippocampus

Seizures

Ethanol

14 Citations (Scopus)

Sexually divergent DNA methylation patterns with hippocampal aging

Masser, D. R., Hadad, N., Porter, H. L., Mangold, C. A., Unnikrishnan, A., Ford, M., Giles, C. B., Georgescu, C., Dozmorov, M. G., Wren, J. D., Richardson, A., Stanford, D. R. & Freeman, W. M., 2017, (Accepted/In press) In : Aging Cell.

Research output: Contribution to journal › Article

DNA Methylation

Methylation

Genome

Epigenomics

Sex Characteristics

30 Citations (Scopus)

Sexually divergent induction of microglial-associated neuroinflammation with hippocampal aging

Mangold, C. A., Wronowski, B., Du, M., Masser, D. R., Hadad, N., Bixler, G. V., Brucklacher, R. M., Ford, M., Sonntag, W. E. & Freeman, W. M., Jul 21 2017, In : Journal of Neuroinflammation. 14, 1, 141.

Research output: Contribution to journal › Article

Sex Characteristics

Gene Expression

Hippocampus

Gene Expression Regulation

Microglia

2016

20 Citations (Scopus)

Absence of genomic hypomethylation or regulation of cytosine-modifying enzymes with aging in male and female mice

Hadad, N., Masser, D. R., Logan, S., Wronowski, B., Mangold, C. A., Clark, N., Otalora, L., Unnikrishnan, A., Ford, M., Giles, C. B., Wren, J. D., Richardson, A., Sonntag, W. E., Stanford, D. R. & Freeman, W., Jul 13 2016, In : Epigenetics and Chromatin. 9, 1, 30.

Research output: Contribution to journal › Article

Cytosine

Methylation

Enzymes

Dioxygenases

Methyltransferases

2015

12 Citations (Scopus)

Effect of nucleus accumbens shell infusions of ganaxolone or gaboxadol on ethanol consumption in mice

Ramaker, M. J., Strong-Kaufman, M. N., Ford, M., Phillips, T. & Finn, D. D., Apr 1 2015, In : Psychopharmacology. 232, 8, p. 1415-1426 12 p.

Research output: Contribution to journal › Article

Nucleus Accumbens

Ethanol

GABA-A Receptors

Pregnanolone

Steroids

3 Citations (Scopus)

Nicotinic receptors in non-human primates: Analysis of genetic and functional conservation with humans

Shorey-Kendrick, L. E., Ford, M., Allen, D. C., Kuryatov, A., Lindstrom, J., Wilhelm, L., Grant, K. K. & Spindel, E., Jun 27 2015, In : Neuropharmacology. 96, PB, p. 263-273 11 p., 5737.

Research output: Contribution to journal › Article

Nicotinic Receptors

Nicotine

Primates

Macaca fascicularis

Macaca

5 Citations (Scopus)

Null Mutation of 5α-Reductase Type I Gene Alters Ethanol Consumption Patterns in a Sex-Dependent Manner

Ford, M., Nickel, J. D., Kaufman, M. N. & Finn, D. D., May 1 2015, In : Behavior Genetics. 45, 3, p. 341-353 13 p.

Research output: Contribution to journal › Article

ethanol

mutation

Oxidoreductases

Ethanol

Pregnanolone

12 Citations (Scopus)

Sex Differences in Ethanol’s Anxiolytic Effect and Chronic Ethanol Withdrawal Severity in Mice with a Null Mutation of the 5α-Reductase Type 1 Gene

Tanchuck-Nipper, M. A., Ford, M., Hertzberg, A., Beadles-Bohling, A., Cozzoli, D. K. & Finn, D. D., May 1 2015, In : Behavior Genetics. 45, 3, p. 354-367 14 p.

Research output: Contribution to journal › Article

tranquilizers

Anti-Anxiety Agents

gender differences

Sex Characteristics

ethanol

2014

7 Citations (Scopus)

Applications of schedule-induced polydipsia in rodents for the study of an excessive ethanol intake phenotype

Ford, M., 2014, In : Alcohol. 48, 3, p. 265-276 12 p.

Research output: Contribution to journal › Article

Polydipsia

Rodentia

Appointments and Schedules

Ethanol

food

13 Citations (Scopus)

Differences in the reinstatement of ethanol seeking with ganaxolone and gaboxadol

Ramaker, M. J., Ford, M., Phillips, T. & Finn, D. D., Jul 11 2014, In : Neuroscience. 272, p. 180-187 8 p.

Research output: Contribution to journal › Article

Ethanol

GABA-A Receptors

Pregnanolone

Alcohols

Aptitude

21 Citations (Scopus)

Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice

Crabbe, J. J., Metten, P., Belknap, J., Spence, S. E., Cameron, A. J., Schlumbohm, J. P., Huang, L. C., Barkley-Levenson, A. M., Ford, M. & Phillips, T., Feb 2014, In : Genes, Brain and Behavior. 13, 2, p. 236-246 11 p.

Research output: Contribution to journal › Article

Drinking

Ethanol

Behavioral Genetics

Alcohols

Phenotype

12 Citations (Scopus)

Quantification of ten neuroactive steroids in plasma in Withdrawal Seizure-Prone and -Resistant mice during chronic ethanol withdrawal

Snelling, C., Tanchuck-Nipper, M. A., Ford, M., Jensen, J. P., Cozzoli, D. K., Ramaker, M. J., Helms, M., Crabbe, J. J., Rossi, D. J. & Finn, D. D., Sep 1 2014, In : Psychopharmacology. 231, 17, p. 3401-3414 14 p.

Research output: Contribution to journal › Article

Seizures

Ethanol

Steroids

Pregnanolone

Gas Chromatography-Mass Spectrometry

2013

6 Citations (Scopus)

Contribution of NMDA glutamate and nicotinic acetylcholine receptor mechanisms in the discrimination of ethanolnicotine mixtures

Ford, M., Davis, N. L., McCracken, A. D. & Grant, K. K., Oct 2013, In : Behavioural Pharmacology. 24, 7, p. 617-622 6 p.

Research output: Contribution to journal › Article

Nicotinic Receptors

N-Methylaspartate

Nicotine

Glutamic Acid

Ethanol

30 Citations (Scopus)

The Influence of Fetal Ethanol Exposure on Subsequent Development of the Cerebral Cortex as Revealed by Magnetic Resonance Imaging

Leigland, L. A., Ford, M., Lerch, J. P. & Kroenke, C. C., Jun 2013, In : Alcoholism: Clinical and Experimental Research. 37, 6, p. 924-932 9 p.

Research output: Contribution to journal › Article

Magnetic resonance

Fetal Alcohol Spectrum Disorders

Cerebral Cortex

Ethanol

Magnetic Resonance Imaging

11 Citations (Scopus)

The relationship between adjunctive drinking, blood ethanol concentration and plasma corticosterone across fixed-time intervals of food delivery in two inbred mouse strains

Ford, M., Steele, A. M., McCracken, A. D., Finn, D. D. & Grant, K. K., Nov 2013, In : Psychoneuroendocrinology. 38, 11, p. 2598-2610 13 p.

Research output: Contribution to journal › Article

Inbred Strains Mice

Corticosterone

Drinking

Ethanol

Food

2012

25 Citations (Scopus)

A genetic animal model of differential sensitivity to methamphetamine reinforcement

Shabani, S., Dobbs, L. K., Ford, M., Mark, G., Finn, D. D. & Phillips, T., Jun 2012, In : Neuropharmacology. 62, 7, p. 2168-2176 9 p.

Research output: Contribution to journal › Article

Methamphetamine

Genetic Models

Animal Models

Drinking

Intraventricular Infusions

13 Citations (Scopus)

Discrimination of ethanol-nicotine drug mixtures in mice: Dual interactive mechanisms of overshadowing and potentiation

Ford, M., McCracken, A. D., Davis, N. L., Ryabinin, A. & Grant, K. K., Dec 2012, In : Psychopharmacology. 224, 4, p. 537-548 12 p.

Research output: Contribution to journal › Article

Nicotine

Ethanol

Pharmaceutical Preparations

Discrimination (Psychology)

Stimulus Generalization

18 Citations (Scopus)

Effect of ganaxolone and THIP on operant and limited-access ethanol self-administration

Ramaker, M. J., Strong, M. N., Ford, M. & Finn, D. D., Sep 2012, In : Neuropharmacology. 63, 4, p. 555-564 10 p.

Research output: Contribution to journal › Article

Self Administration

Ethanol

GABA-A Receptors

Pregnanolone

Neurotransmitter Agents

2011

26 Citations (Scopus)

Alteration of ethanol drinking in mice via modulation of the GABA A receptor with ganaxolone, finasteride, and gaboxadol

Ramaker, M. J., Ford, M., Fretwell, A. M. & Finn, D. D., Nov 2011, In : Alcoholism: Clinical and Experimental Research. 35, 11, p. 1994-2007 14 p.

Research output: Contribution to journal › Article

Finasteride

GABA-A Receptors

Drinking

Neurotransmitter Agents

Ethanol

37 Citations (Scopus)

Assessment of GABA-B, metabotropic glutamate, and opioid receptor involvement in an animal model of binge drinking

Tanchuck, M. A., Yoneyama, N., Ford, M., Fretwell, A. M. & Finn, D. D., Feb 2011, In : Alcohol. 45, 1, p. 33-44 12 p.

Research output: Contribution to journal › Article

Aminobutyrates

Binge Drinking

self-administration

Metabotropic Glutamate Receptors

Opioid Receptors

34 Citations (Scopus)

Role of training dose in drug discrimination: A review

Stolerman, I. P., Childs, E., Ford, M. & Grant, K. K., Sep 2011, In : Behavioural Pharmacology. 22, 5-6, p. 415-429 15 p.

Research output: Contribution to journal › Article

Pharmaceutical Preparations

Pharmacology

Hallucinogens

Opioid Analgesics

Neurotransmitter Agents

11 Citations (Scopus)

The Influence of Selection for Ethanol Withdrawal Severity on Traits Associated With Ethanol Self-Administration and Reinforcement

Ford, M., Fretwell, A. M., Anacker, A. M. J., Crabbe, J. J., Mark, G. & Finn, D. D., Feb 2011, In : Alcoholism: Clinical and Experimental Research. 35, 2, p. 326-337 12 p.

Research output: Contribution to journal › Article

Self Administration

Reinforcement

Ethanol

Cues

Seizures

2010

45 Citations (Scopus)

Manipulation of GABAergic steroids: Sex differences in the effects on alcohol drinking- and withdrawal-related behaviors

Finn, D. D., Beckley, E. H., Kaufman, K. R. & Ford, M., Jan 2010, In : Hormones and Behavior. 57, 1, p. 12-22 11 p.

Research output: Contribution to journal › Article

Sex Characteristics

Alcohol Drinking

Ethanol

Steroids

Pregnanolone

14 Citations (Scopus)

Repeated ethanol administration modifies the temporal structure of sucrose intake patterns in mice: Effects associated with behavioral sensitization

Pastor, R., Kamens, H. M., McKinnon, C. S., Ford, M. & Phillips, T., 2010, In : Addiction Biology. 15, 3, p. 324-335 12 p.

Research output: Contribution to journal › Article

Sucrose

Ethanol

Pharmaceutical Preparations

GABA-B Receptors

Aminobutyrates

2009

14 Citations (Scopus)

Selected line difference in the effects of ethanol dependence and withdrawal on allopregnanolone levels and 5α-Reductase Enzyme Activity and Expression

Tanchuck, M. A., Long, S. L., Ford, M., Hashimoto, J., Crabbe, J. J., Roselli, C., Wiren, K. & Finn, D. D., Dec 2009, In : Alcoholism: Clinical and Experimental Research. 33, 12, p. 2077-2087 11 p.

Research output: Contribution to journal › Article

Pregnanolone

Enzyme activity

Oxidoreductases

Ethanol

Seizures

24 Citations (Scopus)

The influence of mecamylamine on ethanol and sucrose self-administration

Ford, M., Fretwell, A. M., Nickel, J. D., Mark, G., Strong, M. N., Yoneyama, N. & Finn, D. D., Sep 2009, In : Neuropharmacology. 57, 3, p. 250-258 9 p.

Research output: Contribution to journal › Article

Mecamylamine

Self Administration

Sucrose

Ethanol

Drinking

2008

20 Citations (Scopus)

Ethanol intake patterns in female mice: Influence of allopregnanolone and the inhibition of its synthesis

Ford, M., Beckley, E. H., Nickel, J. D., Eddy, S. & Finn, D. D., Sep 1 2008, In : Drug and Alcohol Dependence. 97, 1-2, p. 73-85 13 p.

Research output: Contribution to journal › Article

Pregnanolone

Ethanol

self-administration

manipulation

brain

36 Citations (Scopus)

Inhibition of 5α-reduced steroid biosynthesis impedes acquisition of ethanol drinking in male C57BL/6J mice

Ford, M., Yoneyama, N., Strong, M. N., Fretwell, A., Tanchuck, M. & Finn, D. D., Aug 2008, In : Alcoholism: Clinical and Experimental Research. 32, 8, p. 1408-1416 9 p.

Research output: Contribution to journal › Article

Finasteride

Biosynthesis

Inbred C57BL Mouse

Drinking

Ethanol

28 Citations (Scopus)

Reinstatement of ethanol and sucrose seeking by the neurosteroid allopregnanolone in C57BL/6 mice

Finn, D. D., Mark, G., Fretwell, A. M., Gililland-Kaufman, K. R., Strong, M. N. & Ford, M., Dec 2008, In : Psychopharmacology. 201, 3, p. 423-433 11 p.

Research output: Contribution to journal › Article

Pregnanolone

Inbred C57BL Mouse

Neurotransmitter Agents

Sucrose

Ethanol

19 Citations (Scopus)

The neurosteroid environment in the hippocampus exerts bi-directional effects on seizure susceptibility in mice

Gililland-Kaufman, K. R., Tanchuck, M. A., Ford, M., Crabbe, J. J., Beadles-Bohling, A. S., Snelling, C., Mark, G. & Finn, D. D., Dec 3 2008, In : Brain Research. 1243, p. 113-123 11 p.

Research output: Contribution to journal › Article

Pregnanolone

Neurotransmitter Agents

Hippocampus

Seizures

Anticonvulsants

176 Citations (Scopus)

Voluntary ethanol consumption in 22 inbred mouse strains

Yoneyama, N., Crabbe, J. J., Ford, M., Murillo, A. & Finn, D. D., May 2008, In : Alcohol. 42, 3, p. 149-160 12 p.

Research output: Contribution to journal › Article

Inbred Strains Mice

Ethanol

Bottles

Saccharin

water

2007

43 Citations (Scopus)

Allopregnanolone influences the consummatory processes that govern ethanol drinking in C57BL/6J mice

Ford, M., Mark, G., Nickel, J. D., Phillips, T. & Finn, D. D., May 16 2007, In : Behavioural Brain Research. 179, 2, p. 265-272 8 p.

Research output: Contribution to journal › Article

Pregnanolone

Inbred C57BL Mouse

Drinking

Ethanol

Self Administration

18 Citations (Scopus)

Influence of reinforcement schedule on ethanol consumption patterns in non-food restricted male C57BL/6J mice

Ford, M., Fretwell, A. M., Mark, G. & Finn, D. D., Feb 2007, In : Alcohol. 41, 1, p. 21-29 9 p.

Research output: Contribution to journal › Article

Reinforcement Schedule

Inbred C57BL Mouse

reinforcement

Reinforcement

Ethanol

217 Citations (Scopus)

Mouse inbred strain differences in ethanol drinking to intoxication

Rhodes, J. S., Ford, M., Yu, C. H., Brown, L. L., Finn, D. D., Garland, T. & Crabbe, J. J., Feb 2007, In : Genes, Brain and Behavior. 6, 1, p. 1-18 18 p.

Research output: Contribution to journal › Article

Inbred Strains Mice

Drinking

Ethanol

Water

Photoperiod

2006

109 Citations (Scopus)

A new look at the 5α-reductase inhibitor finasteride

Finn, D. D., Beadles-Bohling, A. S., Beckley, E. H., Ford, M., Gililland, K. R., Gorin-Meyer, R. E. & Wiren, K., Mar 2006, In : CNS Drug Reviews. 12, 1, p. 53-76 24 p.

Research output: Contribution to journal › Article

Finasteride

Oxidoreductases

Steroids

20-alpha-Dihydroprogesterone

Protein Isoforms

49 Citations (Scopus)

Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: Potential role of endogenous neurosteroids?

Ford, M., Nickel, J. D. & Finn, D. D., Aug 2006, In : Alcohol. 37, 1, p. 23-33 11 p.

Research output: Contribution to journal › Article

Finasteride

Inbred C57BL Mouse

withdrawal

Neurotransmitter Agents

Ethanol

2005

70 Citations (Scopus)

Neurosteroid modulators of GABAA receptors differentially modulate ethanol intake patterns in male C57BL/6J mice

Ford, M., Nickel, J. D., Phillips, T. & Finn, D. D., Sep 2005, In : Alcoholism: Clinical and Experimental Research. 29, 9, p. 1630-1640 11 p.

Research output: Contribution to journal › Article

Pregnanolone

GABA-A Receptors

Inbred C57BL Mouse

Modulators

Neurotransmitter Agents

2004

34 Citations (Scopus)

Determination of an Estradiol Dose-Response Relationship in the Modulation of Ethanol Intake

Ford, M., Eldridge, J. C. & Samson, H. H., Jan 2004, In : Alcoholism: Clinical and Experimental Research. 28, 1, p. 20-28 9 p.

Research output: Contribution to journal › Article

Estradiol

Ethanol

Modulation

Self Administration

Plasmas

70 Citations (Scopus)

Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL/6 mice

Finn, D. D., Sinnott, R. S., Ford, M., Long, S. L., Tanchuck, M. A. & Phillips, T., 2004, In : Neuroscience. 123, 4, p. 813-819 7 p.

Research output: Contribution to journal › Article

Pregnanolone

Inbred C57BL Mouse

Sex Characteristics

Ethanol

Injections

75 Citations (Scopus)

The role of pregnane neurosteroids in ethanol withdrawal: Behavioral genetic approaches

Finn, D. D., Ford, M., Wiren, K., Roselli, C. & Crabbe, J. J., Feb 2004, In : Pharmacology and Therapeutics. 101, 2, p. 91-112 22 p.

Research output: Contribution to journal › Article

Pregnanolone

Behavioral Genetics

Pregnanes

Neurotransmitter Agents

Ethanol

2002

39 Citations (Scopus)

Ethanol consumption in the female Long-Evans rat: A modulatory role of estradiol

Ford, M., Eldridge, J. C. & Samson, H. H., 2002, In : Alcohol. 26, 2, p. 103-113 11 p.

Research output: Contribution to journal › Article

Long Evans Rats

Rats

Estradiol

Ethanol

Group

60 Citations (Scopus)

Microanalysis of ethanol self-administration: Estrous cycle phase-related changes in consumption patterns

Ford, M. & Eldridge, J. C., 2002, In : Alcoholism: Clinical and Experimental Research. 26, 5, p. 635-643 9 p.

Research output: Contribution to journal › Article

Self Administration

Estrous Cycle

Microanalysis

Ethanol

Estrus