Mary Stenzel-Poore

Professor

  • 6779 Citations
  • 41 h-Index
1985 …2019

Research output per year

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Research Output

2019

Preconditioning in the Rhesus Macaque Induces a Proteomic Signature Following Cerebral Ischemia that Is Associated with Neuroprotection

Stevens, S. L., Liu, T., Bahjat, F. R., Petyuk, V. A., Schepmoes, A. A., Sontag, R. L., Gritsenko, M. A., Wu, C., Wang, S., Shukla, A. K., Jacobs, J. M., Smith, R. D., Rodland, K. D., Alexander West, G., Kohama, S. G., Glynn, C. & Stenzel-Poore, M. P., Aug 15 2019, In : Translational Stroke Research. 10, 4, p. 440-448 9 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Statistical detection of differentially abundant ions in mass spectrometry-based imaging experiments with complex designs

Bemis, K. A., Guo, D., Harry, A. J., Thomas, M., Lanekoff, I., Stenzel-Poore, M., Stevens, S. L., Laskin, J. & Vitek, O., Jan 1 2018, (Accepted/In press) In : International Journal of Mass Spectrometry.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Preclinical Development of a Prophylactic Neuroprotective Therapy for the Preventive Treatment of Anticipated Ischemia-Reperfusion Injury

Bahjat, F., Alexander West, G., Kohama, S., Glynn, C., Urbanski, H., Hobbs, T., Earl, E., Stevens, S. L. & Stenzel-Poore, M., Apr 5 2017, (Accepted/In press) In : Translational Stroke Research. p. 1-12 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

TLR sensing of bacterial spore-associated RNA triggers host immune responses with detrimental effects

Choo, M. K., Sano, Y., Kim, C., Yasuda, K., Li, X. D., Lin, X., Stenzel-Poore, M., Alexopoulou, L., Ghosh, S., Latz, E., Rifkin, I. R., Chen, Z. J., Stewart, G. C., Chong, H. & Park, J. M., May 1 2017, In : Journal of Experimental Medicine. 214, 5, p. 1297-1311 15 p.

Research output: Contribution to journalArticle

8 Scopus citations

Translational Stroke Research: Vision and Opportunities

Bosetti, F., Koenig, J. I., Ayata, C., Back, S., Becker, K., Broderick, J. P., Carmichael, T. T., Cho, S., Cipolla, M. J., Corbett, D., Corriveau, R. A., Cramer, S. C., Ferguson, A. R., Finklestein, S. P., Ford, B. D., Furie, K. L., Hemmen, T. M., Iadecola, C., Jakeman, L. B., Janis, S. & 22 others, Jauch, E. C., Johnston, K. C., Kochanek, P. M., Kohn, H., Lo, E. H., Lyden, P. D., Mallard, C., McCullough, L. D., McGavern, L. M., Meschia, J. F., Moy, C. S., Perez-Pinzon, M. A., Ramadan, I., Savitz, S. I., Schwamm, L. H., Steinberg, G. K., Stenzel-Poore, M., Tymianski, M., Warach, S., Wechsler, L. R., Zhang, J. H. & Koroshetz, W., Jul 27 2017, (Accepted/In press) In : Stroke.

Research output: Contribution to journalArticle

28 Scopus citations
2016

Cytosolic receptor melanoma differentiation-associated protein 5 mediates preconditioning-induced neuroprotection against cerebral ischemic injury

Gesuete, R., Christensen, S. N., Bahjat, F. R., Packard, A. E. B., Stevens, S. L., Liu, M., Salazar, A. M. & Stenzel-Poore, M. P., Jan 1 2016, In : Stroke. 47, 1, p. 262-266 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Role of circulating immune cells in stroke and preconditioning- induced protection

Gesuete, R., Stevens, S. L. & Stenzel-Poore, M. P., Jan 1 2016, Acta Neurochirurgica, Supplementum. Springer-Verlag Wien, p. 39-44 6 p. (Acta Neurochirurgica, Supplementum; vol. 121).

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations
2015

CpG preconditioning regulates miRNA expression that modulates genomic reprogramming associated with neuroprotection against ischemic injury

Vartanian, K. B., Mitchell, H. D., Stevens, S. L., Conrad, V. K., McDermott, J. E. & Stenzel-Poore, M. P., Feb 2 2015, In : Journal of Cerebral Blood Flow and Metabolism. 35, 2, p. 257-266 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

GDF10 is a signal for axonal sprouting and functional recovery after stroke

Li, S., Nie, E. H., Yin, Y., Benowitz, L. I., Tung, S., Vinters, H. V., Bahjat, F. R., Stenzel-Poore, M. P., Kawaguchi, R., Coppola, G. & Carmichael, S. T., Nov 25 2015, In : Nature Neuroscience. 18, 12, p. 1737-1745 9 p.

Research output: Contribution to journalArticle

60 Scopus citations
2014

Immunological Mechanisms and Therapies in Brain Injuries and Stroke

Chen, J., Hu, X., Stenzel-Poore, M. & Zhang, J. H., Jan 1 2014, Springer New York. 386 p.

Research output: Book/ReportBook

1 Scopus citations

Matrix effects in biological mass spectrometry imaging: Identification and compensation

Lanekoff, I., Stevens, S. L., Stenzel-Poore, M. P. & Laskin, J., Jun 16 2014, In : Analyst. 139, 14, p. 3528-3532 5 p.

Research output: Contribution to journalArticle

43 Scopus citations

Reprogramming the response to stroke by preconditioning

Stevens, S. L., Vartanian, K. B. & Stenzel-Poore, M. P., Aug 2014, In : Stroke. 45, 8, p. 2527-2531 5 p.

Research output: Contribution to journalArticle

19 Scopus citations

Toll-like receptors and ischemic brain injury

Gesuete, R., Kohama, S. G. & Stenzel-Poore, M. P., May 2014, In : Journal of Neuropathology and Experimental Neurology. 73, 5, p. 378-386 9 p.

Research output: Contribution to journalReview article

58 Scopus citations

Toll-like receptors in ischemic stroke and other acute brain injuries

Bahjat, F., Gesuete, R. & Stenzel-Poore, M., Jan 1 2014, Immunological Mechanisms and Therapies in Brain Injuries and Stroke. Springer New York, p. 97-120 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2013

Modeling emergence in neuroprotective regulatory networks

Sanfilippo, A. P., Haack, J. N., McDermott, J. E., Stevens, S. L. & Stenzel-Poore, M., 2013, Complex Sciences - 2nd International Conference, COMPLEX 2012, Revised Selected Papers. Springer Verlag, Vol. 126 LNICST. p. 291-302 12 p. (Lecture Notes of the Institute for Computer Sciences, Social-Informatics and Telecommunications Engineering, LNICST; vol. 126 LNICST).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Steps to Translate Preconditioning from Basic Research to the Clinic

Bahjat, F. R., Gesuete, R. & Stenzel-Poore, M. P., Jan 1 2013, In : Translational Stroke Research. 4, 1, p. 89-103 15 p.

Research output: Contribution to journalReview article

17 Scopus citations

The genomics of preconditioning and ischemic tolerance

Vartanian, K. B., Stevens, S. L. & Stenzel-Poore, M., Jan 1 2013, Innate Tolerance in the CNS: Translational Neuroprotection by Pre- and Post-Conditioning. Springer New York, p. 363-386 24 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2012

Changes in Spontaneous Activity Assessed by Accelerometry Correlate with Extent of Cerebral Ischemia-Reperfusion Injury in the Nonhuman Primate

Urbanski, H. F., Kohama, S. G., West, G. A., Glynn, C., Williams-Karnesky, R. L., Earl, E., Neuringer, M. N., Renner, L., Weiss, A., Stenzel-Poore, M. & Bahjat, F. R., Dec 1 2012, In : Translational Stroke Research. 3, 4, p. 442-451 10 p.

Research output: Contribution to journalArticle

5 Scopus citations
45 Scopus citations
12 Scopus citations

Identification and validation of ifit1 as an important innate immune bottleneck

McDermott, J. E., Vartanian, K. B., Mitchell, H., Stevens, S. L., Sanfilippo, A. & Stenzel-Poore, M. P., Jun 20 2012, In : PloS one. 7, 6, e36465.

Research output: Contribution to journalArticle

17 Scopus citations

Modeling Dynamic Regulatory Processes in Stroke

McDermott, J. E., Jarman, K., Taylor, R., Lancaster, M., Shankaran, H., Vartanian, K. B., Stevens, S. L., Stenzel-Poore, M. P. & Sanfilippo, A., Oct 1 2012, In : PLoS computational biology. 8, 10, e1002722.

Research output: Contribution to journalArticle

1 Scopus citations

Poly-ICLC preconditioning protects the blood-brain barrier against ischemic injury in vitro through type i interferon signaling

Gesuete, R., Packard, A. E. B., Vartanian, K. B., Conrad, V. K., Stevens, S. L., Bahjat, F. R., Yang, T. & Stenzel-Poore, M. P., Nov 1 2012, In : Journal of Neurochemistry. 123, SUPPL. 2, p. 75-85 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

Poly-IC preconditioning protects against cerebral and renal ischemia-reperfusion injury

Packard, A. E. B., Hedges, J. C., Bahjat, F. R., Stevens, S. L., Conlin, M. J., Salazar, A. M. & Stenzel-Poore, M. P., Feb 1 2012, In : Journal of Cerebral Blood Flow and Metabolism. 32, 2, p. 242-247 6 p.

Research output: Contribution to journalArticle

29 Scopus citations

TLR9 bone marrow chimeric mice define a role for cerebral TNF in neuroprotection induced by CpG preconditioning

Packard, A. E. B., Leung, P. Y., Vartanian, K. B., Stevens, S. L., Bahjat, F. R. & Stenzel-Poore, M. P., Dec 1 2012, In : Journal of Cerebral Blood Flow and Metabolism. 32, 12, p. 2193-2200 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Toll-like receptor 7 preconditioning induces robust neuroprotection against stroke by a novel type i interferon-mediated mechanism

Leung, P. Y., Stevens, S. L., Packard, A. E. B., Lessov, N. S., Yang, T., Conrad, V. K., Van Den Dungen, N. N. A. M., Simon, R. P. & Stenzel-Poore, M. P., May 1 2012, In : Stroke. 43, 5, p. 1383-1389 7 p.

Research output: Contribution to journalArticle

48 Scopus citations

Toll-like receptor agonists as antecedent therapy for ischemic brain injury: Advancing preclinical studies to the nonhuman primate

Bahjat, F., Vartanian, K. B., West, G. A. & Stenzel-Poore, M., Jan 1 2012, Translational Stroke Research: From Target Selection to Clinical Trials. Springer New York, p. 205-230 26 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2011

Corticotropin-releasing hormone (CRH) transgenic mice display hyperphagia with increased Agouti-related protein mRNA in the hypothalamic arcuate nucleus

Nakayama, S., Nishiyama, M., Iwasaki, Y., Shinahara, M., Okada, Y., Tsuda, M., Okazaki, M., Tsugita, M., Taguchi, T., Makino, S., Poore, M. P. S., Hashimoto, K. & Terada, Y., May 13 2011, In : Endocrine Journal. 58, 4, p. 279-286 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

CRF receptor antagonist astressin-B reverses and prevents alopecia in CRF over-expressing mice

Wang, L., Million, M., Rivier, J., Rivier, C., Craft, N., Stenzel-Poore, M. P. & Taché, Y., Feb 28 2011, In : PloS one. 6, 2, e16377.

Research output: Contribution to journalArticle

23 Scopus citations

Defining the players in higher-order networks: Predictive modeling for reverse engineering functional influence networks

McDermott, J. E., Archuleta, M., Stevens, S. L., Stenzel-Poore, M. P. & Sanfilippo, A., Dec 1 2011, Pacific Symposium on Biocomputing 2011, PSB 2011. p. 314-325 12 p. (Pacific Symposium on Biocomputing 2011, PSB 2011).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

11 Scopus citations

Dissection of corticotropin-releasing factor system involvement in locomotor sensitivity to methamphetamine

Giardino, W. J., Pastor, R., Anacker, A. M. J., Spangler, E., Cote, D. M., Li, J., Stenzel-Poore, M. P., Phillips, T. J. & Ryabinin, A. E., Feb 1 2011, In : Genes, Brain and Behavior. 10, 1, p. 78-89 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Ethanol concentration-dependent effects and the role of stress on ethanol drinking in corticotropin-releasing factor type 1 and double type 1 and 2 receptor knockout mice

Pastor, R., Reed, C., Burkhart-Kasch, S., Li, N., Sharpe, A. L., Coste, S. C., Stenzel-Poore, M. P. & Phillips, T. J., Nov 1 2011, In : Psychopharmacology. 218, 1, p. 169-177 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury

Vartanian, K. B., Stevens, S. L., Marsh, B. J., Williams-Karnesky, R., Lessov, N. S. & Stenzel-Poore, M. P., Oct 14 2011, In : Journal of Neuroinflammation. 8, 140.

Research output: Contribution to journalArticle

92 Scopus citations

Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury

Stevens, S. L., Leung, P. Y., Vartanian, K. B., Gopalan, B., Yang, T., Simon, R. P. & Stenzel-Poore, M. P., Jun 8 2011, In : Journal of Neuroscience. 31, 23, p. 8456-8463 8 p.

Research output: Contribution to journalArticle

88 Scopus citations

Proof of concept: Pharmacological preconditioning with a Toll-like receptor agonist protects against cerebrovascular injury in a primate model of stroke

Bahjat, F. R., Williams-Karnesky, R. L., Kohama, S. G., West, G. A., Doyle, K. P., Spector, M. D., Hobbs, T. R. & Stenzel-Poore, M. P., May 1 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 5, p. 1229-1242 14 p.

Research output: Contribution to journalArticle

39 Scopus citations
2010

An integrated approach to predictive genomic analytics

McDermott, J. E., Baddeley, B., Stevens, S., Sanfilippo, A., Riensche, R., Stenzel-Poore, M., Taylor, R. & Jensen, R., Oct 25 2010, 2010 ACM International Conference on Bioinformatics and Computational Biology, ACM-BCB 2010. p. 390-393 4 p. (2010 ACM International Conference on Bioinformatics and Computational Biology, ACM-BCB 2010).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

CRF2 null mutation increases sensitivity to isolation rearing effects on locomotor activity in mice

Gresack, J., Powell, S., Geyer, M., Poore, M. S., Coste, S. & Risbrough, V., Aug 1 2010, In : Neuropeptides. 44, 4, p. 349-353 5 p.

Research output: Contribution to journalArticle

8 Scopus citations

Isolation rearing-induced deficits in contextual fear learning do not require CRF2 receptors

Gresack, J. E., Risbrough, V. B., Scott, C. N., Coste, S., Stenzel-Poore, M., Geyer, M. A. & Powell, S. B., May 1 2010, In : Behavioural Brain Research. 209, 1, p. 80-84 5 p.

Research output: Contribution to journalArticle

34 Scopus citations

Toll-Like receptor tolerance as a mechanism for neuroprotection

Vartanian, K. B. & Stenzel-Poore, M. P., Dec 1 2010, In : Translational Stroke Research. 1, 4, p. 252-260 9 p.

Research output: Contribution to journalReview article

37 Scopus citations
2009

Adenosine and stroke: Maximizing the therapeutic potential of adenosine as a prophylactic and acute neuroprotectant

Williams-Karnesky, R. L. & Stenzel-Poore, M. P., Oct 12 2009, In : Current Neuropharmacology. 7, 3, p. 217-227 11 p.

Research output: Contribution to journalReview article

34 Scopus citations

A new model of cortical stroke in the rhesus macaque

West, G. A., Golshani, K. J., Doyle, K. P., Lessov, N. S., Hobbs, T. R., Kohama, S. G., Pike, M. M., Kroenke, C. D., Grafe, M. R., Spector, M. D., Tobar, E. T., Simon, R. P. & Stenzel-Poore, M. P., Jun 1 2009, In : Journal of Cerebral Blood Flow and Metabolism. 29, 6, p. 1175-1186 12 p.

Research output: Contribution to journalArticle

41 Scopus citations

Corticotropin-releasing factor-overexpressing mice exhibit reduced neuronal activation in the arcuate nucleus and food intake in response to fasting

Stengel, A., Goebel, M., Million, M., Stenzel-Poore, M. P., Kobelt, P., Mönnikes, H., Taché, Y. & Wang, L., Jan 1 2009, In : Endocrinology. 150, 1, p. 153-160 8 p.

Research output: Contribution to journalArticle

24 Scopus citations

CRF 1 and CRF 2 receptors are required for potentiated startle to contextual but not discrete cues

Risbrough, V. B., Geyer, M. A., Hauger, R. L., Coste, S., Stenzel-Poore, M., Wurst, W. & Holsboer, F., May 1 2009, In : Neuropsychopharmacology. 34, 6, p. 1494-1503 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

CRF enhancement of GIRK channel-mediated transmission in dopamine neurons

Beckstead, M. J., Gantz, S. C., Ford, C. P., Stenzel-Poore, M. P., Phillips, P. E. M., Mark, G. P. & Williams, J. T., Jul 1 2009, In : Neuropsychopharmacology. 34, 8, p. 1926-1935 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Inflammation and the emerging role of the toll-like receptor system in acute brain ischemia

Marsh, B. J., Stevens, S. L., Hunter, B. & Stenzel-Poore, M. P., Mar 1 2009, In : Stroke. 40, 3 SUPPL. 1, p. S34-S37

Research output: Contribution to journalArticle

37 Scopus citations

It's all in the family: Multiple toll-like receptors offer promise as novel therapeutic targets for stroke neuroprotection

Leung, P. Y., Packard, A. E. B. & Stenzel-Poore, M. P., Jun 19 2009, In : Future Neurology. 4, 2, p. 201-208 8 p.

Research output: Contribution to journalReview article

13 Scopus citations

Plasma adiponectin levels are increased despite insulin resistance in corticotropin-releasing hormone transgenic mice, an animal model of Cushing syndrome

Shinahara, M., Nishiyama, M., Iwasaki, Y., Nakayama, S., Noguchi, T., Kambayashi, M., Okada, Y., Tsuda, M., Stenzel-Poore, M. P., Hashimoto, K. & Terada, Y., Nov 9 2009, In : Endocrine Journal. 56, 7, p. 879-886 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Systemic lipopolysaccharide protects the brain from ischemic injury by reprogramming the response of the brain to stroke: A critical role for IRF3

Marsh, B., Stevens, S. L., Packard, A. E. B., Gopalan, B., Hunter, B., Leung, P. Y., Harrington, C. A. & Stenzel-Poore, M. P., Aug 5 2009, In : Journal of Neuroscience. 29, 31, p. 9839-9849 11 p.

Research output: Contribution to journalArticle

148 Scopus citations

Toll-like receptor signaling in endogenous neuroprotection and stroke

Marsh, B. J., Williams-Karnesky, R. L. & Stenzel-Poore, M. P., Feb 6 2009, In : Neuroscience. 158, 3, p. 1007-1020 14 p.

Research output: Contribution to journalReview article

178 Scopus citations
2008

Corticotropin-releasing factor-1 receptor involvement in behavioral neuroadaptation to ethanol: A urocortin1-independent mechanism

Pastor, R., McKinnon, C. S., Scibelli, A. C., Burkhart-Kasch, S., Reed, C., Ryabinin, A. E., Coste, S. C., Stenzel-Poore, M. P. & Phillips, T. J., Jul 1 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 26, p. 9070-9075 6 p.

Research output: Contribution to journalArticle

52 Scopus citations