Mark Woods

Associate Professor

  • 3887 Citations
  • 28 h-Index
1985 …2019

Research output per year

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Research Output

2019

Crystal Structures of DOTMA Chelates from Ce3+ to Yb3+: Evidence for a Continuum of Metal Ion Hydration States

Woods, M., Payne, K. M., Valente, E. J., Kucera, B. E. & Young, V. G., Jul 25 2019, In : Chemistry - A European Journal. 25, 42, p. 9997-10005 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Differences in the relaxometric properties of regioisomeric benzyl-DOTA bifunctional chelators: Implications for molecular imaging

Rust, L., Payne, K. M., Carniato, F., Botta, M. & Woods, M., May 15 2019, In : Bioconjugate Chemistry. 30, 5, p. 1530-1538 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

Gadolinium chelate safety in pregnancy: Barely detectable gadolinium levels in the juvenile nonhuman primate after in utero exposure

Prola-Netto, J., Woods, M., Roberts, V., Sullivan, E., Miller, C. A., Frias, A. & Oh, K., Jan 1 2018, In : Radiology. 286, 1, p. 122-128 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

ParaCEST agents encapsulated in Reverse Nano-Assembled Capsules (RACs): How slow molecular tumbling can quench CEST contrast

Farashishiko, A., Slack, J. R., Botta, M. & Woods, M., Apr 1 2018, In : Frontiers in Chemistry. 6, APR, 96.

Research output: Contribution to journalArticle

1 Scopus citations

Response

Prola-Netto, J., Woods, M., Roberts, V., Frias, A. & Oh, K., Aug 1 2018, In : Radiology. 288, 2, p. 634-635 2 p.

Research output: Contribution to journalLetter

2017

Crosslinked shells for nano-assembled capsules: A new encapsulation method for smaller Gd3+-loaded capsules with exceedingly high relaxivities

Farashishiko, A., Plush, S. E., Maier, K. B., Dean Sherry, A. & Woods, M., Jan 1 2017, In : Chemical Communications. 53, 47, p. 6355-6358 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

On Water and its Effect on the Performance of T1-Shortening Contrast Agents

Payne, K. M., Wilds, J. M., Carniato, F., Botta, M. & Woods, M., 2017, (Accepted/In press) In : Israel Journal of Chemistry.

Research output: Contribution to journalArticle

2 Scopus citations
2016

Nano assembly and encapsulation; a versatile platform for slowing the rotation of polyanionic Gd3+-based MRI contrast agents

Farashishiko, A., Chacón, K. N., Blackburn, N. & Woods, M., 2016, (Accepted/In press) In : Contrast Media and Molecular Imaging.

Research output: Contribution to journalArticle

2 Scopus citations
19 Scopus citations
2015

Aggregation in amphiphilic macrocycle-substituted Gd3+ DOTA-type chelates is affected by the regiochemistry of substitution

Webber, B. C., Cassino, C., Botta, M. & Woods, M., Mar 2 2015, In : Inorganic Chemistry. 54, 5, p. 2085-2087 3 p.

Research output: Contribution to journalArticle

5 Scopus citations

Effect of repeated glucagon doses on hepatic glycogen in type 1 Diabetes: Implications for a bihormonal Closed-Loop system

Castle, J. R., Youssef, J. E., Bakhtiani, P. A., Cai, Y., Stobbe, J. M., Branigan, D., Ramsey, K., Jacobs, P., Reddy, R., Woods, M. & Ward, W. K., Nov 2015, In : Diabetes care. 38, 11, p. 2115-2119 5 p.

Research output: Contribution to journalArticle

17 Scopus citations

Gadolinium chelate contrast material in pregnancy: Fetal biodistribution in the nonhuman primate

Oh, K. Y., Roberts, V. H. J., Schabel, M. C., Grove, K. L., Woods, M. & Frias, A. E., Jul 1 2015, In : RADIOLOGY. 276, 1, p. 110-118 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Isomerism in benzyl-DOTA derived bifunctional chelators: Implications for molecular imaging

Payne, K. M. & Woods, M., Feb 18 2015, In : Bioconjugate Chemistry. 26, 2, p. 338-344 7 p.

Research output: Contribution to journalArticle

9 Scopus citations
2014

Human whole-blood 1H2O longitudinal relaxation with normal and high-relaxivity contrast reagents: Influence of trans-cell-membrane water exchange

Wilson, G. J., Woods, M., Springer, C. S., Bastawrous, S., Bhargava, P. & Maki, J. H., Dec 1 2014, In : Magnetic Resonance in Medicine. 72, 6, p. 1746-1754 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

The confluence of structure and dynamics in lanthanide(iii) chelates: How dynamics help define structure in solution

Webber, B. C. & Woods, M., Jan 7 2014, In : Dalton Transactions. 43, 1, p. 251-258 8 p.

Research output: Contribution to journalArticle

8 Scopus citations
6 Scopus citations
8 Scopus citations
2013

Coupling fast water exchange to slow molecular tumbling in Gd3+ chelates: Why faster is not always better

Avedano, S., Botta, M., Haigh, J. S., L. Longo, D. & Woods, M., Aug 5 2013, In : Inorganic Chemistry. 52, 15, p. 8436-8450 15 p.

Research output: Contribution to journalArticle

21 Scopus citations

Picture of a chelate in exchange: The crystal structure of NaHoDOTMA, a “semi”-hydrated chelate

Payne, K. M., Valente, E. J., Aime, S., Botta, M. & Woods, M., Feb 21 2013, In : Chemical Communications. 49, 23, p. 2320-2322 3 p.

Research output: Contribution to journalArticle

6 Scopus citations
2012

Chemical exchange saturation transfer is unaffected by modest changes in pressure

Webber, B. C., Carney, C. E. & Woods, M., Apr 1 2012, In : European Journal of Inorganic Chemistry. 12, p. 2040-2043 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Structural analysis of isomeric europium(III) chelates of NB-DOTMA

Webber, B. C. & Woods, M., Aug 6 2012, In : Inorganic Chemistry. 51, 15, p. 8576-8582 7 p.

Research output: Contribution to journalArticle

17 Scopus citations
2011

Analysis of the conformational behavior and stability of the SAP and TSAP isomers of lanthanide(III) NB-DOTA-type chelates

Tircso, G., Webber, B. C., Kucera, B. E., Young, V. G. & Woods, M., Sep 5 2011, In : Inorganic Chemistry. 50, 17, p. 7966-7979 14 p.

Research output: Contribution to journalArticle

31 Scopus citations

Imaging the extracellular pH of tumors by MRI after injection of a single cocktail of T 1 and T 2 contrast agents

Martinez, G. V., Zhang, X., García-Martín, M. L., Morse, D. L., Woods, M., Sherry, A. D. & Gillies, R. J., Dec 1 2011, In : NMR in biomedicine. 24, 10, p. 1380-1391 12 p.

Research output: Contribution to journalArticle

52 Scopus citations

Investigations into whole water, prototropic and amide proton exchange in lanthanide(III) DOTA-tetraamide chelates

Woods, M., Pasha, A., Zhao, P., Tircso, G., Chowdhury, S., Kiefer, G., Woessner, D. E. & Sherry, A. D., Jul 7 2011, In : Dalton Transactions. 40, 25, p. 6759-6764 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

LDL-based nanoparticles for contrast enhanced MRI of atheroplaques in mouse models

Yamakoshi, Y., Qiao, H., Lowell, A. N., Woods, M., Paulose, B., Nakao, Y., Zhang, H., Liu, T., Lund-Katz, S. & Zhou, R., Aug 21 2011, In : Chemical Communications. 47, 31, p. 8835-8837 3 p.

Research output: Contribution to journalArticle

23 Scopus citations

Properties, solution state behavior, and crystal structures of chelates of DOTMA

Aime, S., Botta, M., Garda, Z., Kucera, B. E., Tircso, G., Young, V. G. & Woods, M., Sep 5 2011, In : Inorganic Chemistry. 50, 17, p. 7955-7965 11 p.

Research output: Contribution to journalArticle

57 Scopus citations

Strategies for labeling proteins with PARACEST agents

Vasalatiy, O., Zhao, P., Woods, M., Marconescu, A., Castillo-Muzquiz, A., Thorpe, P., Kiefer, G. E. & Dean Sherry, A., Feb 1 2011, In : Bioorganic and Medicinal Chemistry. 19, 3, p. 1106-1114 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Towards the rational design of MRI contrast agents: δ-Substitution of lanthanide(III) NB-DOTA-tetraamide chelates influences but does not control coordination geometry

Carney, C. E., Tran, A. D., Wang, J., Schabel, M. C., Sherry, A. D. & Woods, M., Sep 5 2011, In : Chemistry - A European Journal. 17, 37, p. 10372-10378 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
2010

CEST and PARACEST MR contrast agents

Hancu, I., Dixon, W. T., Woods, M., Vinogradov, E., Sherry, A. D. & Lenkinski, R. E., Oct 1 2010, In : Acta Radiologica. 51, 8, p. 910-923 14 p.

Research output: Contribution to journalReview article

80 Scopus citations

Polymeric PARACEST MRI contrast agents as potential reporters for gene therapy

Wu, Y., Carney, C. E., Denton, M., Hart, E., Zhao, P., Streblow, D. N., Sherry, A. D. & Woods, M., Dec 7 2010, In : Organic and Biomolecular Chemistry. 8, 23, p. 5333-5338 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

The population of SAP and TSAP isomers in cyclen-based lanthanide(III) chelates is substantially affected by solvent

Miller, K. J., Saherwala, A. A., Webber, B. C., Wu, Y., Sherry, A. D. & Woods, M., Oct 4 2010, In : Inorganic Chemistry. 49, 19, p. 8662-8664 3 p.

Research output: Contribution to journalArticle

29 Scopus citations
2009

Effect of the regiochemistry of butyl amide substituents on the solution-state structures of lanthanide(III) DOTA-tetraamide complexes

Mani, T., Tircsó, G., Zhao, P., Sherry, A. D. & Woods, M., Nov 2 2009, In : Inorganic Chemistry. 48, 21, p. 10338-10345 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Nanoassembled capsules as delivery vehicles for large payloads of high relaxivity Gd3+ agents

Plush, S. E., Woods, M., Zhou, Y. F., Kadali, S. B., Wong, M. S. & Sherry, A. D., Nov 4 2009, In : Journal of the American Chemical Society. 131, 43, p. 15918-15923 6 p.

Research output: Contribution to journalArticle

33 Scopus citations
11 Scopus citations

Synthesis and evaluation of lanthanide ion DOTA-tetraamide complexes bearing peripheral hydroxyl groups

Pasha, A., Lin, M., Tircsó, G., Rostollan, C. L., Woods, M., Kiefer, G. E., Sherry, A. D. & Sun, X., Mar 1 2009, In : Journal of Biological Inorganic Chemistry. 14, 3, p. 421-438 18 p.

Research output: Contribution to journalArticle

14 Scopus citations
2008

Chemical exchange saturation transfer contrast agents for magnetic resonance imaging

Sherry, A. D. & Woods, M., Sep 1 2008, In : Annual Review of Biomedical Engineering. 10, p. 391-411 21 p.

Research output: Contribution to journalReview article

247 Scopus citations

Modulation of water exchange in europium(III) DOTA-tetraamide complexes via electronic substituent effects

Ratnakar, S. J., Woods, M., Lubag, A. J. M., Kovács, Z. & Sherry, A. D., Jan 9 2008, In : Journal of the American Chemical Society. 130, 1, p. 6-7 2 p.

Research output: Contribution to journalArticle

58 Scopus citations

Polymeric PARACEST agents for enhancing MRI contrast sensitivity

Wu, Y., Zhou, Y., Ouari, O., Woods, M., Zhao, P., Soesbe, T. C., Kiefer, G. E. & Sherry, A. D., Oct 22 2008, In : Journal of the American Chemical Society. 130, 42, p. 13854-13855 2 p.

Research output: Contribution to journalArticle

55 Scopus citations

Synthesis and relaxometric studies of a dendrimer-based pH-responsive MRI contrast agent

Ali, M. M., Woods, M., Caravan, P., Opina, A. C. L., Spiller, M., Fettinger, J. C. & Sherry, A. D., Aug 18 2008, In : Chemistry - A European Journal. 14, 24, p. 7250-7258 9 p.

Research output: Contribution to journalArticle

81 Scopus citations

The effect of the amide substituent on the biodistribution and tolerance of lanthanide(iii) dota-tetraamide derivatives

Woods, M., Caravan, P., Geraldes, C. F. G. C., Greenfield, M. T., Kiefer, G. E., Lin, M., McMillan, K., Prata, M. I. M., Santos, A. C., Sun, X., Wang, J., Zhang, S., Zhao, P. & Sherry, A. D., Dec 1 2008, In : Investigative Radiology. 43, 12, p. 861-870 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Towards the rational design of MRI contrast agents: Electron spin relaxation is largely unaffected by the coordination geometry of gadolinium(III)-DOTA-type complexes

Borel, A., Bean, J. F., Clarkson, R. B., Helm, L., Moriggi, L., Sherry, A. D. & Woods, M., Mar 17 2008, In : Chemistry - A European Journal. 14, 9, p. 2658-2667 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2007

A bridge to coordination isomer selection in lanthanide(III) DOTA-tetraamide complexes

Vipond, J., Woods, M., Zhao, P., Tircsó, G., Ren, J., Bott, S. G., Ogrin, D., Kiefer, G. E., Kovacs, Z. & Sherry, A. D., Apr 2 2007, In : Inorganic Chemistry. 46, 7, p. 2584-2595 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Albumin-binding PARACEST agents

Ali, M. M., Woods, M., Suh, E. H., Kovacs, Z., Tircsó, G., Zhao, P., Kodibagkar, V. D. & Sherry, A. D., Aug 1 2007, In : Journal of Biological Inorganic Chemistry. 12, 6, p. 855-865 11 p.

Research output: Contribution to journalArticle

30 Scopus citations

PARACEST contrast agents

Sherry, A. D. & Woods, M., Jan 1 2007, Molecular and Cellular MR Imaging. CRC Press, p. 101-122 22 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Potentiometric and relaxometric properties of a gadolinium-based MRI contrast agent for sensing tissue pH

Kálmán, F. K., Woods, M., Caravan, P., Jurek, P., Spiller, M., Tircsó, G., Király, R., Brúcher, E. & Sherry, A. D., Jun 25 2007, In : Inorganic Chemistry. 46, 13, p. 5260-5270 11 p.

Research output: Contribution to journalArticle

91 Scopus citations

Spectral properties of a bifunctional PARACEST europium chelate: An intermediate for targeted imaging applications

Adair, C., Woods, M., Zhao, P., Pasha, A., Winter, P. M., Lanza, G. M., Athey, P., Sherry, A. D. & Kiefer, G. E., May 18 2007, In : Contrast Media and Molecular Imaging. 2, 1, p. 55-58 4 p.

Research output: Contribution to journalArticle

23 Scopus citations
2006

Europium(III) macrocyclic complexes with alcohol pendant groups as chemical exchange saturation transfer agents

Woods, M., Woessner, D. E., Zhao, P., Pasha, A., Yang, M. Y., Huang, C. H., Vasalitiy, O., Morrow, J. R. & Sherry, A. D., Aug 9 2006, In : Journal of the American Chemical Society. 128, 31, p. 10155-10162 8 p.

Research output: Contribution to journalArticle

55 Scopus citations

Paramagnetic lanthanide complexes as PARACEST agents for medical imaging

Woods, M., Woessner, D. E. & Sherry, A. D., May 26 2006, In : Chemical Society Reviews. 35, 6, p. 500-511 12 p.

Research output: Contribution to journalArticle

298 Scopus citations
2005

Bifunctional chelators: An important tool in the development of inorganic pharmaceuticals

Woods, M. & Sherry, A. D., Jan 1 2005, In : Chimica Oggi. 23, 1, p. 31-34 4 p.

Research output: Contribution to journalReview article

4 Scopus citations

Structural and chiroptical properties of the two coordination isomers of YbDOTA-type complexes

Di Bari, L., Pescitelli, G., Sherry, A. D. & Woods, M., Nov 14 2005, In : Inorganic Chemistry. 44, 23, p. 8391-8398 8 p.

Research output: Contribution to journalArticle

45 Scopus citations