Mark Asquith

Research Assistant Professor

  • 1069 Citations
  • 16 h-Index
20102019
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Research Output 2010 2019

  • 1069 Citations
  • 16 h-Index
  • 29 Article
  • 2 Review article
  • 1 Chapter
  • 1 Short survey
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Article
2019

Controlling for contaminants in low-biomass 16S rRNA gene sequencing experiments

Karstens, L., Asquith, M., Davin, S., Fair, D., Gregory, W. T., Wolfe, A. J., Braun, J. & McWeeney, S., Jul 1 2019, In : mSystems. 4, 4, e00290-19.

Research output: Contribution to journalArticle

Open Access
Biomass
rRNA Genes
Sequencing
microbial communities
Genes
1 Citation (Scopus)

Disruption of Intestinal Homeostasis and Intestinal Microbiota During Experimental Autoimmune Uveitis

Janowitz, C., Nakamura, Y. K., Metea, C., Gligor, A., Yu, W., Karstens, L., Rosenbaum, J. J., Asquith, M. & Lin, P., Jan 2 2019, In : Investigative ophthalmology & visual science. 60, 1, p. 420-429 10 p.

Research output: Contribution to journalArticle

Uveitis
Homeostasis
Permeability
Peptides
Dysbiosis

HLA Alleles Associated With Risk of Ankylosing Spondylitis and Rheumatoid Arthritis Influence the Gut Microbiome

Asquith, M., Sternes, P. R., Costello, M. E., Karstens, L., Diamond, S., Martin, T., Li, Z., Marshall, M. S., Spector, T. D., le Cao, K. A., Rosenbaum, J. J. & Brown, M. A., Jan 1 2019, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

Ankylosing Spondylitis
Rheumatoid Arthritis
Alleles
Microbiota
Genotype
2018
2 Citations (Scopus)
Microbiota
Biomass
Urinary Tract
Vagina
Urinary Tract Infections
17 Citations (Scopus)

Effects of HLA-B27 on Gut Microbiota in Experimental Spondyloarthritis Implicate an Ecological Model of Dysbiosis

Gill, T., Asquith, M., Brooks, S. R., Rosenbaum, J. J. & Colbert, R. A., Jan 1 2018, (Accepted/In press) In : Arthritis and Rheumatology.

Research output: Contribution to journalArticle

Dysbiosis
HLA-B27 Antigen
Transgenic Rats
Inbred F344 Rats
HLA-B7 Antigen
3 Citations (Scopus)

Spondyloarthritis, acute anterior uveitis, and fungi: Updating the catterall-king hypothesis

Laurence, M., Asquith, M. & Rosenbaum, J. J., Apr 1 2018, In : Frontiers in Medicine. 5, APR, 80.

Research output: Contribution to journalArticle

Anterior Uveitis
Psoriasis
Multiple Sclerosis
Fungi
Mycoses
2 Citations (Scopus)

Spondyloarthritis, acute anterior uveitis, and fungi: Updating the Catterall-King hypothesis

Laurence, M., Asquith, M. & Rosenbaum, J. J., Apr 1 2018, In : Frontiers in Medicine. 5, APR, 80.

Research output: Contribution to journalArticle

Open Access
Anterior Uveitis
Psoriasis
Multiple Sclerosis
Fungi
Mycoses
4 Citations (Scopus)

The microbiome and HLA-B27-associated acute anterior uveitis

Rosenbaum, J. J. & Asquith, M., Jan 1 2018, (Accepted/In press) In : Nature Reviews Rheumatology.

Research output: Contribution to journalArticle

Anterior Uveitis
HLA-B27 Antigen
Microbiota
Dysbiosis
Reactive Arthritis
2017
9 Citations (Scopus)

Estrogen protection against EAE modulates the microbiota and mucosal-associated regulatory cells

Benedek, G., Zhang, J., Nguyen, H., Kent, G., Seifert, H. A., Davin, S., Stauffer, P., Vandenbark, A., Karstens, L., Asquith, M. & Offner, H., Sep 15 2017, In : Journal of Neuroimmunology. 310, p. 51-59 9 p.

Research output: Contribution to journalArticle

Encephalomyelitis
Microbiota
Estrogens
Gonadal Steroid Hormones
Multiple Sclerosis
12 Citations (Scopus)

Intestinal Metabolites Are Profoundly Altered in the Context of HLA-B27 Expression and Functionally Modulate Disease in a Rat Model of Spondyloarthritis

Asquith, M., Davin, S., Stauffer, P., Michell, C., Janowitz, C., Lin, P., Ensign-Lewis, J., Kinchen, J. M., Koop, D. & Rosenbaum, J. J., Oct 1 2017, In : Arthritis & rheumatology (Hoboken, N.J.). 69, 10, p. 1984-1995 12 p.

Research output: Contribution to journalArticle

HLA-B27 Antigen
Transgenic Rats
Propionates
Microbiota
Inflammation
16 Citations (Scopus)

Short chain fatty acids ameliorate immune-mediated uveitis partially by altering migration of lymphocytes from the intestine

Nakamura, Y. K., Janowitz, C., Metea, C., Asquith, M., Karstens, L., Rosenbaum, J. J. & Lin, P., Dec 1 2017, In : Scientific Reports. 7, 1, 11745.

Research output: Contribution to journalArticle

Volatile Fatty Acids
Uveitis
Intestines
Lymphocytes
Lymph Nodes
2016
6 Citations (Scopus)

Does the Microbiome Cause B27-related Acute Anterior Uveitis?

Rosenbaum, J. J., Lin, P. & Asquith, M., Mar 20 2016, (Accepted/In press) In : Ocular Immunology and Inflammation. p. 1-5 5 p.

Research output: Contribution to journalArticle

Anterior Uveitis
Microbiota
Dysbiosis
Molecular Mimicry
Bacterial Translocation
59 Citations (Scopus)

Does the urinary microbiome play a role in urgency urinary incontinence and its severity?

Karstens, L., Asquith, M., Davin, S., Stauffer, P., Fair, D., Gregory, W. T., Rowsenbaum, J. T., McWeeney, S. & Nardos, R., Jul 27 2016, In : Frontiers in cellular and infection microbiology. 6, JUL, 78.

Research output: Contribution to journalArticle

Microbiota
Urinary Incontinence
Bacteria
Urinary Tract
Urinary Bladder
37 Citations (Scopus)

Gut microbial alterations associated with protection from autoimmune uveitis

Nakamura, Y. K., Metea, C., Karstens, L., Asquith, M., Gruner, H., Moscibrocki, C., Lee, I., Brislawn, C. J., Jansson, J. K., Rosenbaum, J. J. & Lin, P., Jul 1 2016, In : Investigative Ophthalmology and Visual Science. 57, 8, p. 3747-3758 12 p.

Research output: Contribution to journalArticle

Uveitis
Anti-Bacterial Agents
Eragrostis
Gastrointestinal Contents
Cluster Analysis
30 Citations (Scopus)

Perturbed Mucosal Immunity and Dysbiosis Accompany Clinical Disease in a Rat Model of Spondyloarthritis

Asquith, M., Stauffer, P., Davin, S., Mitchell, C., Lin, P. & Rosenbaum, J. J., Sep 1 2016, In : Arthritis and Rheumatology. 68, 9, p. 2151-2162 12 p.

Research output: Contribution to journalArticle

Dysbiosis
Mucosal Immunity
Th17 Cells
Bacteria
Immunoglobulin A
18 Citations (Scopus)
Spondylarthropathies
Microbiota
Ankylosing Spondylitis
Reactive Arthritis
Endoplasmic Reticulum Stress
10 Citations (Scopus)

The microbiome, HLA, and the pathogenesis of uveitis

Rosenbaum, J. J., Lin, P. & Asquith, M., Jan 1 2016, In : Japanese Journal of Ophthalmology. 60, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Microbiota
Uveitis
Immune System
Bacteria
2015
14 Citations (Scopus)
Anterior Uveitis
Optical Coherence Tomography
Cell Differentiation
Uveitis
Anterior Chamber
49 Citations (Scopus)

The intestinal microbiome in spondyloarthritis

Gill, T., Asquith, M., Rosenbaum, J. J. & Colbert, R. A., Aug 24 2015, In : Current Opinion in Rheumatology. 27, 4, p. 319-325 7 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Dysbiosis
Juvenile Arthritis
Clostridium
Ankylosing Spondylitis
2014
29 Citations (Scopus)

Chronic Ethanol Consumption Modulates Growth Factor Release, Mucosal Cytokine Production, and MicroRNA Expression in Nonhuman Primates

Asquith, M., Pasala, S., Engelmann, F., Haberthur, K., Meyer, C., Park, B., Grant, K. K. & Messaoudi, I., 2014, In : Alcoholism: Clinical and Experimental Research. 38, 4, p. 980-993 14 p.

Research output: Contribution to journalArticle

MicroRNAs
Primates
Intercellular Signaling Peptides and Proteins
Ethanol
Cytokines
17 Citations (Scopus)

Does the microbiome play a causal role in spondyloarthritis?

Rosenbaum, J. J., Lin, P., Asquith, M., Costello, M. E., Kenna, T. J. & Brown, M. A., 2014, In : Clinical Rheumatology. 33, 6, p. 763-767 5 p.

Research output: Contribution to journalArticle

Microbiota
HLA-B27 Antigen
Transgenic Rats
beta 2-Microglobulin
Joint Diseases
113 Citations (Scopus)

HLA-B27 and human β2-microglobulin affect the gut microbiota of transgenic rats

Lin, P., Bach, M., Asquith, M., Lee, A. Y., Akileswaran, L., Stauffer, P., Davin, S., Pan, Y., Cambronne, E., Dorris, M., Debelius, J. W., Lauber, C. L., Ackermann, G., Baeza, Y. V., Gill, T., Knight, R., Colbert, R. A., Taurog, J. D., Van Gelder, R. N. & Rosenbaum, J. J., Aug 20 2014, In : PLoS One. 9, 8, e105684.

Research output: Contribution to journalArticle

Transgenic Rats
HLA-B27 Antigen
intestinal microorganisms
Rats
genetically modified organisms
40 Citations (Scopus)

The role of the gut and microbes in the pathogenesis of spondyloarthritis

Asquith, M., Elewaut, D., Lin, P. & Rosenbaum, J. J., 2014, In : Best Practice and Research: Clinical Rheumatology. 28, 5, p. 687-702 16 p.

Research output: Contribution to journalArticle

Inflammatory Bowel Diseases
Culture Techniques
Microbiota
Inflammation
Health
2013
7 Citations (Scopus)

Genome-wide analysis of t cell responses during acute and latent simian varicella virus infections in rhesus macaques

Haberthur, K., Kraft, A., Arnold, N., Park, B., Meyer, C., Asquith, M., Dewane, J. & Messaoudi, I., 2013, In : Journal of Virology. 87, 21, p. 11751-11761 11 p.

Research output: Contribution to journalArticle

Cercopithecine herpesvirus 9
Human herpesvirus 3
Human Herpesvirus 3
Chickenpox
Virus Diseases
10 Citations (Scopus)

Moderate alcohol consumption enhances vaccine-induced responses in rhesus macaques

Messaoudi, I., Asquith, M., Engelmann, F., Park, B., Brown, M., Rau, A., Shaw, J. & Grant, K. K., Dec 17 2013, In : Vaccine. 32, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

Macaca mulatta
Vaccinia
Alcohol Drinking
Vaccinium
Ethanol
2012
254 Citations (Scopus)

IL-1β mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4 + Th17 cells

Coccia, M., Harrison, O. J., Schiering, C., Asquith, M., Becher, B., Powrie, F. & Maloy, K. J., Aug 2012, In : Journal of Experimental Medicine. 209, 9, p. 1595-1609 15 p.

Research output: Contribution to journalArticle

Th17 Cells
Interleukin-17
Interleukin-1
Lymphocytes
Inflammation
2010
107 Citations (Scopus)

OX40 is required for regulatory T cell-mediated control of colitis

Griseri, T., Asquith, M., Thompson, C. & Powrie, F., Apr 12 2010, In : Journal of Experimental Medicine. 207, 4, p. 699-709 11 p.

Research output: Contribution to journalArticle

Regulatory T-Lymphocytes
Colitis
Colon
Gastrointestinal Tract
Homeostasis
68 Citations (Scopus)

Pathogenic and protective roles of MyD88 in leukocytes and epithelial cells in mouse models of inflammatory bowel disease

Asquith, M., Boulard, O., Powrie, F. & Maloy, K. J., 2010, In : Gastroenterology. 139, 2

Research output: Contribution to journalArticle

Toll-Like Receptors
Inflammatory Bowel Diseases
Leukocytes
Epithelial Cells
Intestines
23 Citations (Scopus)

TLR2-independent induction and regulation of chronic intestinal inflammation

Boulard, O., Asquith, M., Powrie, F. & Maloy, K. J., Feb 2010, In : European Journal of Immunology. 40, 2, p. 516-524 9 p.

Research output: Contribution to journalArticle

Inflammation
Th1 Cells
Tight Junctions
Adaptive Immunity
Inflammatory Bowel Diseases